The Oncosearch | Oncotarget

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Christine B. Ambrosone, Allyson C. Young, Lara E. Sucheston, Dan Wang, Li Yan, Song Liu, Li Tang, Qiang Hu, Jo L. Freudenheim, Peter G. Shields, Carl D. Morrison, Kitaw Demissie, Michael J. Higgins

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 237-248

Keywords: DNA methylation, breast cancer, disparities, estrogen receptor, African-American, genome-wide

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer Research Paper

Gab-Yong Bae, So-Jung Choi, Ji-Seon Lee, Jisuk Jo, Jinseon Lee, Jhingook Kim, Hyuk-Jin Cha

Published Nov 29, 2013 · Vol. 4, No. 12 · pp. 2512-2522

Keywords: E-Cadherin, EGFR-MEK/ERK signaling, ZEB1, MMP2, Invasion

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

Jason U. Tilan, Congyi Lu, Susana Galli, Ewa Izycka-Swieszewska, Joshua P. Earnest, Asim Shabbir, Lindsay M. Everhart, Shuo Wang, Samantha Martin, Meredith Horton, Akanksha Mahajan, David Christian, Alison O'Neill, Hongkun Wang, Tingting Zhuang, Magdalena Czarnecka, Michael D. Johnson, Jeffrey A. Toretsky, Joanna B. Kitlinska

Published Nov 26, 2013 · Vol. 4, No. 12 · pp. 2487-2501

Keywords: Neuropeptide Y, Ewing sarcoma, hypoxia, cancer stem cells, angiogenesis

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7 Research Paper

Zeran Wang, Yueyong Liu, Pengju Zhang, Weiguo Zhang, Weijing Wang, Kenneth Curr, Guangwei Wei, Jian-Hua Mao

Published Nov 25, 2013 · Vol. 4, No. 12 · pp. 2476-2486

Keywords: FAM83D, FBXW7, breast cancer, epithelial-mesenchymal transition, invasion

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Chiou-Tsun Tsai, Pei-Ming Yang, Ting-Rong Chern, Shu-Hui Chuang, Jung-Hsin Lin, Lars Klemm, Markus MÃ¼schen, Ching-Chow Chen

Published Nov 25, 2013 · Vol. 5, No. 1 · pp. 211-223

Keywords: AID, 5-aza-CdR, Zebularine, DNMT1

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Review

Jahangir Abdi, Guoan Chen, Hong Chang

Published Nov 24, 2013 · Vol. 4, No. 12 · pp. 2186-2207

Keywords: multiple myeloma, drug resistance, signaling pathways, oncogenes

Targeting nucleocytoplasmic transport in cancer therapy Review

Richard Hill, Bastien Cautain, Nuria de Pedro, Wolfgang Link

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 11-28

Keywords: Tumor suppressors, Cancer, Anti-cancer therapy, Nuclear export, nuclear import

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Florian Kopp, Ernst Wagner, Andreas Roidl

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 185-195

Keywords: breast cancer, lung cancer, miRNA, K-ras, cell cycle, proliferation

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Akinori Morita, Shinya Ariyasu, Soichiro Ohya, Ippei Takahashi, Bing Wang, Kaoru Tanaka, Takatoshi Uchida, Haruna Okazaki, Kengo Hanaya, Atsushi Enomoto, Mitsuru Nenoi, Masahiko Ikekita, Shin Aoki, Yoshio Hosoi

Published Nov 24, 2013 · Vol. 4, No. 12 · pp. 2439-2450

Keywords: p53, zinc chelator, zinc binding site, radiation, apoptosis

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer. Research Paper

Anastasia Wyce, Yan Degenhardt, Yuchen Bai, BaoChau Le, Susan Korenchuk, Ming-Chih Crouthamel, Charles McHugh, Robert Vessella, Caretha Creasy, Peter Tummino, Olena Barbash

Published Nov 23, 2013 · Vol. 4, No. 12 · pp. 2419-2429

Keywords: BET inhibitor, prostate cancer, c-Myc

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Cristina Branco-Price, Colin E. Evans, Randall S. Johnson

Published Nov 18, 2013 · Vol. 4, No. 12 · pp. 2567-2576

Keywords: Vascular endothelium, hypoxia, metastasis, HIF, HIF isoforms, nitric oxide, cell-specific responses

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Shahin Assefnia, Sivanesan Dakshanamurthy, Jaime M. Guidry Auvil, Constanze Hampel, Panos Z. Anastasiadis, Bhaskar Kallakury, Aykut Uren, David W. Foley, Milton L. Brown, Lawrence Shapiro, Michael Brenner, David Haigh, Stephen W. Byers

Published Nov 15, 2013 · Vol. 5, No. 6 · pp. 1458-1474

Keywords: cadherin-11, breast cancer, glioblastoma, small molecule inhibitor, rheumatoid arthritis, celecoxib

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

Jiateng Zhong, Shavali Shaik, Lixin Wan, Adriana E. Tron, Zhiwei Wang, Liankun Sun, Hiroyuki Inuzuka, Wenyi Wei

Published Nov 6, 2013 · Vol. 4, No. 12 · pp. 2339-2353

Keywords: tumor suppressor, MTSS1, ubiquitination, phosphorylation, migration

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

Jennifer K Wolter, Nikolaus E Wolter, Alvaro Blanch, Teresa Partridge, Lynn Cheng, Daniel A. Morgenstern, Monika Podkowa, David R. Kaplan, Meredith S. Irwin

Published Nov 4, 2013 · Vol. 5, No. 1 · pp. 161-172

Keywords: neuroblastoma, propranolol, beta-adrenergic receptor, p53, p73

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Hsin-Pai Li, Chen-Ching Peng, I-Che Chung, Mei-Yuan Huang, Shao-Tung Huang, Chia-Chun Chen, Kai-Ping Chang, Cheng-Lung Hsu, Yu-Sun Chang

Published Nov 4, 2013 · Vol. 4, No. 11 · pp. 2154-2165

Keywords: HOXA2, DNA methylation, NPC, MMP9

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

Hao Zhang, Wan Lin, Kalpana Kannan, Liming Luo, Jing Li, Pei-Wen Chao, Yan Wang, Yu-Ping Chen, Jiang Gu, Laising Yen

Published Nov 1, 2013 · Vol. 4, No. 11 · pp. 2135-2143

Keywords: Transcriptome, transcription-induced chimeric RNAs, GOLM1-MAK10, secreted fusion protein, cancer biomarker, esophageal cancer

HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

Jung-Ah Hwang, Bo Bin Lee, Yujin Kim, Seong-Eun Park, Kyun Heo, Seung-Hyun Hong, Young-Ho Kim, Joungho Han, Duk-Hwan Kim, Young Mog Shim, Yeon-Su Lee

Published Oct 28, 2013 · Vol. 4, No. 12 · pp. 2317-2325

Keywords: HOXA11, Hypermethylation, Non-small cell lung cancer, Progression, Migration

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

Christian Holzmann, Tatiana Kilch, Sven Kappel, Andrea ArmbrÃ¼ster, Volker Jung, Michael StÃ¶ckle, Ivan Bogeski, Eva C Schwarz, Christine Peinelt

Published Oct 28, 2013 · Vol. 4, No. 11 · pp. 2096-2107

Keywords: Membrane androgen receptor, Orai channel, CRAC channel, prostate cancer, Ca2+ signaling

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Anton George Henssen, Theresa Thor, Andrea Odersky, Lukas Heukamp, Nicolai El-Hindy, Anneleen Beckers, Frank Slpeleman, Kristina Althoff, Simon SchÃ¤fers, Alexander Schramm, Ulrich Sure, Gudrun Fleischhack, Angelika Eggert, Johannes Hubertus Schulte

Published Oct 27, 2013 · Vol. 4, No. 11 · pp. 2080-2095

Keywords: BET bromodomains, BRD4, MYC, JQ1, pediatric brain tumors, targeted therapy

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

Prisca Exertier, Sophie Javerzat, Baigang Wang, MÃ©lanie Franco, John M. Herbert, Natalia Platonova, Marie Winandy, NadÃ¨ge Pujol, Olivier Nivelles, Sandra Ormenese, Virginie Godard, JÃ¼rgen Becker, Roy Bicknell, Raphael Pineau, JÃ¶rg Wilting, Andreas Bikfalvi, Martin Hagedorn

Published Oct 26, 2013 · Vol. 4, No. 12 · pp. 2302-2316

Keywords: Angiogenesis, Eg5 kinesin, Mklp2 kinesin, VEGF, ispinesib

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Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer Research Paper

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7 Research Paper

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Review

Targeting nucleocytoplasmic transport in cancer therapy Review

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer. Research Paper

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer Research Paper

Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects Research Paper

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7 Research Paper

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Review

Targeting nucleocytoplasmic transport in cancer therapy Review

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Research Paper

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer. Research Paper

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

SCFÎ²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma Research Paper

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

HOXA11 hypermethylation is associated with progression of non-small cell lung cancer Research Paper

ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper