The Oncosearch | Oncotarget

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Qiong Wang, Shaoqing Shi, Weiyang He, Mabel T. Padilla, Lin Zhang, Xia Wang, Bin Zhang, Yong Lin

Published Feb 25, 2014 · Vol. 5, No. 5 · pp. 1304-1314

YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin Research Paper

Mohammad Imran Khan, Vaqar Mustafa Adhami, Rahul Kumar Lall, Mario Sechi, Dinesh C. Joshi, Omar M. Haidar, Deeba Nadeem Syed, Imtiaz Ahmad Siddiqui, Shing-Yan Chiu, Hasan Mukhtar

Published Feb 19, 2014 · Vol. 5, No. 9 · pp. 2462-2474

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

Tae-Hyung Kim, Patrick Leslie, Yanping Zhang

Published Feb 18, 2014 · Vol. 5, No. 4 · pp. 860-871

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

Huili Li, Katherine B. Chiappinelli, Angela A. Guzzetta, Hariharan Easwaran, Ray-Whay Chiu Yen, Rajita Vatapalli, Michael J. Topper, Jianjun Luo, Roisin M. Connolly, Nilofer S. Azad, Vered Stearns, Drew M. Pardoll, Nancy Davidson, Peter A. Jones, Dennis J. Slamon, Stephen B. Baylin, Cynthia A. Zahnow, Nita Ahuja

Published Feb 16, 2014 · Vol. 5, No. 3 · pp. 587-598

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Francesco Crea, Akira Watahiki, Luca Quagliata, Hui Xue, Larissa Pikor, Abhijit Parolia, Yuwei Wang, Dong Lin, Wan L. Lam, William L. Farrar, Takao Isogai, Rudolf Morant, Serenella Castori-Eppenberger, Kim N. Chi, Yuzhuo Wang, Cheryl D. Helgason

Published Feb 6, 2014 · Vol. 5, No. 3 · pp. 764-774

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Powrnima Joshi, Barbara Jacobs, Adeeb Derakhshan, Lee R. Moore, Paul Elson, Pierre L. Triozzi, Ernest Borden, Maciej Zborowski

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2450-2461

Keywords: circulating melanoma cells, CTC, Melan-A, S100B, magnetic separation, negative selection

Caspase-8-mediated PAR-4 cleavage is required for TNFÎ±-induced apoptosis Research Paper

Fabian Treude, Ferdinand Kappes, Dirk Fahrenkamp, Gerhard MÃ¼ller-Newen, Federico Dajas-Bailador, Oliver H. KrÃ¤mer, Bernhard LÃ¼scher, JÃ¶rg Hartkamp

Published Jan 29, 2014 · Vol. 5, No. 10 · pp. 2988-2998

Keywords: PAR-4, apoptosis, caspase-8, tumor suppressor, TNFÎ±

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Tobias Forster, Vanessa Rausch, Yiyao Zhang, Orkhan Isayev, Katharina Heilmann, Frank Schoensiegel, Li Liu, Michelle Nessling, Karsten Richter, Sabrina Labsch, Clifford C. Nwaeburu, Juergen Mattern, Jury Gladkich, Nathalia Giese, Jens Werner, Peter Schemmer, Wolfgang Gross, Martha M. Gebhard, Clarissa Gerhauser, Michael Schaefer, Ingrid Herr

Published Jan 22, 2014 · Vol. 5, No. 6 · pp. 1621-1634

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

Richard Knight, Mikhail Gostev, Sergei Ilisavskii, Anne E Willis, Gerry Melino, Alexey V Antonov

Published Jan 21, 2014 · Vol. 5, No. 3 · pp. 659-666

Keywords: oncotargets, drug action mechanisms, polypharmacology

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Pierluigi Gasparini, Luciano Cascione, Matteo Fassan, Francesca Lovat, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carl Morrison, Carlo M. Croce, Charles L. Shapiro, Kay Huebner

Published Jan 21, 2014 · Vol. 5, No. 5 · pp. 1174-1184

Keywords: Triple Negative breast cancer, microRNA, five markers, prognosis, treatments, outcome

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cecile Pautas, Remy Dulery, Thomas Boyer, Jean-Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, Hassan Farhat, Nicolas Boissel, Christine Terre, Herve Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 916-932

Keywords: acute myeloid leukemia, SNP array lesions, gene mutations, gemtuzumab ozogamicin, prognosis

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Jia Liu, Lixin Wan, Pengda Liu, Hiroyuki Inuzuka, Jiankang Liu, Zhiwei Wang, Wenyi Wei

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1026-1037

Keywords: Î²-TRCP, NEDD4, degradation, PTEN, Akt, cancer, phosphorylation, ubiquitination, therapy

Heat shock proteins in multiple myeloma Review

Lei Zhang, Jacqueline H.L. Fok, Faith E. Davies

Published Jan 19, 2014 · Vol. 5, No. 5 · pp. 1132-1148

Keywords: heat shock proteins, multiple myeloma, protein folding, ER stress, haematology

Immunogenicity of targeted lentivectors Research Paper

Cleo Goyvaerts, De Groeve Kurt, Sandra Van Lint, Carlo Heirman, Jo A. Van Ginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans, Karine Breckpot

Published Jan 19, 2014 · Vol. 5, No. 3 · pp. 704-715

Keywords: antitumor immunotherapy, lentiviral vectors, targeting, antigen-presenting cells

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Nicole M.A. White, Olena Masui, Leroi V. DeSouza, Olga Krakovska, Shereen Metias, Alexander D. Romaschin, R.John Honey, Robert Stewart, Kenneth Pace, Jason Lee, Michael AS. Jewett, Georg A. Bjarnason, K.W.Michael Siu, George M. Yousef

Published Jan 18, 2014 · Vol. 5, No. 2 · pp. 506-518

Keywords: kidney cancer, renal cell, carcinoma, iTRAQ, proteomics, Hsp27, urine markers

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Marcella Salzano, Marta VÃ¡zquez-Cedeira, Marta Sanz-GarcÃa, Alberto Valbuena, Sandra Blanco, Isabel F. FernÃ¡ndez, Pedro A. Lazo

Published Jan 17, 2014 · Vol. 5, No. 7 · pp. 1770-1778

Keywords: Breast cancer, VRK1, Radiation, doxorubicin, chemotherapy, DNA damage, 53BP1

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Ukhyun Jo, Kyong Hwa Park, Young Mi Whang, Jae Sook Sung, Nam Hee Won, Jong Kuk Park, Yeul Hong Kim

Published Jan 16, 2014 · Vol. 5, No. 5 · pp. 1265-1278

Keywords: EGFR, endocytosis, gefitinib, lung cancer, Rab25

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

Rebecca M. Martin, Martin Kerr, Mark T.W. Teo, Sarah J. Jevons, Marianne Koritzinsky, Bradly G. Wouters, Selina Bhattarai, Anne E. Kiltie

Published Jan 14, 2014 · Vol. 5, No. 4 · pp. 993-1003

Keywords: MRE11, bladder cancer, post-transcriptional regulation, microRNA, protein stability

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Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin Research Paper

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Caspase-8-mediated PAR-4 cleavage is required for TNFÎ±-induced apoptosis Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Heat shock proteins in multiple myeloma Review

Immunogenicity of targeted lentivectors Research Paper

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin Research Paper

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Caspase-8-mediated PAR-4 cleavage is required for TNFÎ±-induced apoptosis Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

SCFÎ²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Heat shock proteins in multiple myeloma Review

Immunogenicity of targeted lentivectors Research Paper

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper