The Oncosearch | Oncotarget

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Chung-Ching Wang, Dueng-Yuan Hueng, Ai-Fang Huang, Wei-Liang Chen, Shih-Ming Huang, James Yi-Hsin Chan

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2041-2054

Keywords: CD164, human glioma, glioblastoma, autophagy

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

Laura Molina, Hong Yang, Adeola O. Adebayo Michael, Michael Oertel, Aaron Bell, Sucha Singh, Xin Chen, Junyan Tao, Satdarshan P.S. Monga

Published Feb 19, 2019 · Vol. 10, No. 15 · pp. 1475-1490

Transcriptional regulation of mTORC1 in cancer Editorial

Chiara Di Malta, Andrea Ballabio

Published Oct 9, 2018 · Vol. 9, No. 95 · pp. 36734-36735

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-Bclx_L strategies through Mcl-1 down-regulation Research Paper

Marie-Laure Bonnefond, Romane Florent, Sophie Lenoir, Bernard Lambert, Edwige Abeilard, Florence Giffard, Marie-HÃ©lÃ¨ne Louis, Nicolas Elie, MÃ©lanie Briand, Denis Vivien, Laurent Poulain, Pascal Gauduchon, Monique Nâ€™Diaye

Published Sep 21, 2018 · Vol. 9, No. 74 · pp. 33896-33911

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer Research Paper

Dennis Ruder, Vassiliki Papadimitrakopoulou, Kazuhiko Shien, Carmen Behrens, Neda Kalhor, Huiqin Chen, Li Shen, J. Jack Lee, Waun Ki Hong, Ximing Tang, Luc Girard, John D. Minna, Lixia Diao, Jing Wang, Barbara Mino, Pamela Villalobos, Jaime Rodriguez-Canales, Nana E. Hanson, James Sun, Vincent Miller, Joel Greenbowe, Garrett Frampton, Roy S. Herbst, Veera Baladandayuthapani, Ignacio I. Wistuba, Julie G. Izzo

Published Sep 21, 2018 · Vol. 9, No. 74 · pp. 33995-34008

mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs Priority Research Paper

Gizelka David-West, Amanda Ernlund, Abhilash Gadi, Robert J. Schneider

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33064-33076

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

Shinya Ishida, Hiroki Akiyama, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Gaku Oshikawa, Toshikage Nagao, Osamu Miura

Published Jun 1, 2018 · Vol. 9, No. 42 · pp. 26834-26851

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 Research Paper

Mohamed Badawi, Jihye Kim, Anees Dauki, Dhruvitkumar Sutaria, Tasneem Motiwala, Ryan Reyes, Nissar Wani, Shamalatha Kolli, Jinmai Jiang, Christopher C. Coss, Samson T. Jacob, Mitch A. Phelps, Thomas D. Schmittgen

Published May 25, 2018 · Vol. 9, No. 40 · pp. 26032-26045

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death Research Paper

Christian Argueta, Trinayan Kashyap, Boris Klebanov, Thaddeus J. Unger, Cathy Guo, Susie Harrington, Erkan Baloglu, Margaret Lee, William Senapedis, Sharon Shacham, Yosef Landesman

Published May 22, 2018 · Vol. 9, No. 39 · pp. 25529-25544

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

Elliot John Kahen, Andrew Brohl, Diana Yu, Darcy Welch, Christopher L. Cubitt, Jae K. Lee, Yunyun Chen, Sean J. Yoder, Jamie K. Teer, Yonghong O. Zhang, Margaret R. Wallace, Damon R. Reed

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22571-22585

Selumetinib-based therapy in uveal melanoma patient-derived xenografts Research Paper

Didier Decaudin, Rania El Botty, BÃ©rÃ© Diallo, Gerald Massonnet, Justine Fleury, Adnan Naguez, ChloÃ© Raymondie, Emma Davies, Aaron Smith, Joanne Wilson, Colin Howes, Paul D. Smit, Nathalie Cassoux, Sophie Piperno-Neumann, Sergio Roman-Roman, Fariba NÃ©mati

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21674-21686

A subgroup of pleural mesothelioma expresses ALK protein and may be targetable by combined rapamycin and crizotinib therapy Research Paper

Dina MÃ¶nch, Sabine Bode-Erdmann, JÃ¶rg Kalla, JÃ¶rn StrÃ¤ter, Carsten SchwÃ¤nen, Roger Falkenstern-Ge, Siegfried Klumpp, Godehard Friedel, German Ott, Claudia Kalla

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20781-20794

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma Research Paper

Aurelia Lamanuzzi, Ilaria Saltarella, Vanessa Desantis, Maria Antonia Frassanito, Patrizia Leone, Vito Racanelli, Beatrice Nico, Domenico Ribatti, Paolo Ditonno, Marcella Prete, Antonio Giovanni Solimando, Francesco Dammacco, Angelo Vacca, Roberto Ria

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20563-20577

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Ella Lineham, Graham J. Tizzard, Simon J. Coles, John Spencer, Simon J. Morley

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14148-14159

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

Qi Zhang, Ce Shi, Lina Han, Nitin Jain, Kathryn G. Roberts, Helen Ma, Tianyu Cai, Antonio Cavazos, Yoko Tabe, Rodrigo O. Jacamo, Hong Mu, Yang Zhao, Jing Wang, Shuo-Chieh Wu, Fenglin Cao, Zhihong Zeng, Jin Zhou, Yingchang Mi, Elias J. Jabbour, Ross Levine, Sarah K. Tasian, Charles G. Mullighan, David M. Weinstock, David A. Fruman, Marina Konopleva

Published Jan 17, 2018 · Vol. 9, No. 8 · pp. 8027-8041

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer Priority Research Paper

Wei Yang, Gary N. Schwartz, Jonathan D. Marotti, Vivian Chen, Nicole A. Traphagen, Jiang Gui, Todd W. Miller

Published Jan 15, 2018 · Vol. 9, No. 10 · pp. 8810-8822

Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome Research Paper

Xi Song, Qiyang Shen, Liting Fan, Qiuxiao Yu, Xiao Jia, Yu Sun, Wenpei Bai, Jihong Kang

Published Jan 12, 2018 · Vol. 9, No. 15 · pp. 11905-11921

CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans Research Paper

Yujie Li, Sandra Finkbeiner, Athina Ganner, Julia Gerber, Marinella Klein, Manuel Grafe, Jakob Kandzia, Antje Thien, Kathrin Thedieck, Gerhard Breves, Thomas Jank, Ralf Baumeister, Gerd Walz, Elke Neumann- Haefelin

Published Jan 6, 2018 · Vol. 9, No. 11 · pp. 9581-9595

Osteopontinâ€“integrin engagement induces HIF-1Î±â€“TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer Research Paper

Chi-Shuan Fan, Wei-Shone Chen, Li-Li Chen, Chia-Chi Chen, Yu-Ting Hsu, Kee Voon Chua, Horng-Dar Wang, Tze-Sing Huang

Published Dec 22, 2017 · Vol. 9, No. 4 · pp. 4998-5015

microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1 Research Paper

Gang Liu, Feng-Li Chen, Feng Ji, Hao-Dong Fei, Yue Xie, Shou-Guo Wang

Published Dec 15, 2017 · Vol. 9, No. 2 · pp. 2017-2027

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European Cancer and Oncology Congress

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CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

Transcriptional regulation of mTORC1 in cancer Editorial

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-Bclx_L strategies through Mcl-1 down-regulation Research Paper

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer Research Paper

mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs Priority Research Paper

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 Research Paper

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death Research Paper

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

Selumetinib-based therapy in uveal melanoma patient-derived xenografts Research Paper

A subgroup of pleural mesothelioma expresses ALK protein and may be targetable by combined rapamycin and crizotinib therapy Research Paper

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma Research Paper

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer Priority Research Paper

Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome Research Paper

CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans Research Paper

Osteopontinâ€“integrin engagement induces HIF-1Î±â€“TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer Research Paper

microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development Research Paper

Transcriptional regulation of mTORC1 in cancer Editorial

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-BclxL strategies through Mcl-1 down-regulation Research Paper

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of RICTOR/KRAS-altered non-small cell lung cancer Research Paper

mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs Priority Research Paper

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2 Research Paper

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 Research Paper

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death Research Paper

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

Selumetinib-based therapy in uveal melanoma patient-derived xenografts Research Paper

A subgroup of pleural mesothelioma expresses ALK protein and may be targetable by combined rapamycin and crizotinib therapy Research Paper

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma Research Paper

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells Research Paper

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosomeâ€“like acute B-cell lymphoblastic leukemia Research Paper

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer Priority Research Paper

Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of polycystic ovary syndrome Research Paper

CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans Research Paper

Osteopontinâ€“integrin engagement induces HIF-1Î±â€“TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer Research Paper

microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1 Research Paper

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-Bclx_L strategies through Mcl-1 down-regulation Research Paper