The Oncosearch | Oncotarget

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Karoly Szepeshazi, Andrew V. Schally, Norman L. Block, Gabor Halmos, Mehrdad Nadji, Luca Szalontay, Irving Vidaurre, Andrew Abi-Chaker, Ferenc G. Rick

Published Jun 3, 2013 · Vol. 4, No. 5 · pp. 751-760

Keywords: pancreatic carcinoma, targeted therapy, LH-RH receptor, cytotoxic LHRH analog, GnRH, doxorubicin, peptide therapy

Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia Research Paper

Yin Tong, Liangshun You, Hui Liu, Lu Li, Haitao Meng, Qijun Qian, Wenbin Qian

Published Jun 3, 2013 · Vol. 4, No. 6 · pp. 860-874

Keywords: leukemia, oncolytic adenovirus, autophagy, Beclin-1, autophagic cell death, UVRAG

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong-Dong Wang, Geoffrey Neale, Susan Ragsdale, Virginia Valentine, Armita Bahrami, Jamshid Temirov, Stanley Pounds, Jinghui Zhang, Michael A. Dyer

Published Jun 1, 2013 · Vol. 4, No. 6 · pp. 844-859

Keywords: retinoblastoma, RB1, epigenetics

CK2-NCoR signaling cascade promotes prostate tumorigenesis Research Paper

Jung-Yoon Yoo, Beom Jin Lim, Hyo-Kyoung Choi, Soon Won Hong, Ho Sung Jang, Changsoo Kim, Kyung-Hee Chun, Kyung-Chul Choi, HoGeun Yoon

Published May 11, 2013 · Vol. 4, No. 7 · pp. 972-983

Keywords: CK2, NCoR, Prostate cancer, IP-10, transcriptional regulation

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou, Razelle Kurzrock

Published May 1, 2013 · Vol. 4, No. 5 · pp. 705-714

Keywords: P53 mutations, PTEN loss, bevacizumab, Li-Fraumeni syndrome

Necdin, a p53 target gene, in stem cells Editorial

Takashi Asai, Yan Liu, Stephen D Nimer

Published Apr 30, 2013 · Vol. 4, No. 6 · pp. 806-807

Keywords: Necdin, p53, Stem cell, Cancer stem cell, Hematopoiesis

Targeting HSF1 sensitizes cancer cells to HSP90 inhibition Research Paper

Yaoyu Chen, Jinyun Chen, Alice Loo, Savina Jaeger, Linda Bagdasarian, Jianjun Yu, Franklin Chung, Joshua Korn, David Ruddy, Ribo Guo, Margaret Mclaughlin, Fei Feng, Ping Zhu, Frank Stegmeier, Raymond Pagliarini, Dale Porter, Wenlai Zhou

Published Apr 23, 2013 · Vol. 4, No. 6 · pp. 816-829

Keywords: HSF1, cancer cells, HSP90 inhibitor, Melanoma, HCC, DEDD2

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

Alka Mukhopadhyay, Thaer Khoury, Leighton Stein, Protul Shrikant, Ashwani K. Sood

Published Apr 10, 2013 · Vol. 4, No. 4 · pp. 610-621

Keywords: PDEF, SPDEF, CEACAM6, Elevated co-expression, Tumor cell survival, PDEF-CEACAM6 oncogenic axis, Novel targets in breast cancer

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

Otavia Luisa Caballero, Tzeela Cohen, Sita Gurung, Ramon Chua, Peishan Lee, Yao-Tseng Chen, Parmjit Jat, Lloyd J. Old, Andrew J. G. Simpson

Published Mar 27, 2013 · Vol. 4, No. 4 · pp. 531-541

Keywords: Cancer/testis genes, GAGE, XAGE1, SSX, siRNA, melanoma

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Khoi Chu, Kimberkey M. Boley, Ricardo Moraes, Sanford H. Barsky, Fredika M. Robertson

Published Mar 21, 2013 · Vol. 4, No. 3 · pp. 446-462

Keywords: E-Cadherin, Inflammatory Breast Cander, Mesenchymal-Epithelial transition (MET), HIF-1Î±, Metabolism, Glycolysis

TAp73Î²-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics Research Paper

Johanna Rodhe, Edel Kavanagh, Bertrand Joseph

Published Feb 27, 2013 · Vol. 4, No. 2 · pp. 289-297

Keywords: p73Î±, p73Î², p57Kip2, actin cytoskeleton, cell migration, invasion

Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib Research Paper

Raya Faigenbaum, Roni Haklai, Gilad Ben-Baruch, Yoel Kloog

Published Feb 27, 2013 · Vol. 4, No. 2 · pp. 316-328

Keywords: Endometrial cancer, medroxyprogesterone acetate, FTS, Ras, ERÎ±, ERÎ²

DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells Research Paper

M. Zulfiquer Hossain, Megan A. Healey, Calvin Lee, Weijie Poh, Sashidhar R. Yerram, Kalpesh Patel, Nilofer S. Azad, James G. Herman, Scott E. Kern

Published Feb 26, 2013 · Vol. 4, No. 2 · pp. 298-309

Keywords: cancer, gene methylation, demethylation, DNA-intercalator, quinacrine, DNMT inhibitor, epigenetics, silencing and re-activation of gene expression, small molecule-DNA interactions

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Diersch Sandra, Patrick Wenzel, Melanie Szameitat, Philipp Eser, Mariel C Paul, Barbara Seidler, Stefan Eser, Marlena Messer, Maximilian Reichert, Philipp Pagel, Irene Esposito, Roland M Schmid, Dieter Saur, GÃ¼nter Schneider

Published Feb 26, 2013 · Vol. 4, No. 2 · pp. 277-288

Keywords: pancreatic cancer, PI3K, Efemp1, p27, Bez235

Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis Research Paper

Batya Barkan, Adrienne D. Cox, Yoel Kloog

Published Feb 24, 2013 · Vol. 4, No. 2 · pp. 256-268

Keywords: : apoptosis, c-jun, farnesylthiosalicylic acid, FTS, galectin-1, galectin -7, JDP2, NF1, p53, Ras, Salirasib, neurofibromin, NF1

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Dimitra Bourboulia, HuiYing Han, Sandra Jensen-Taubman, Noah Gavil, Biju Isaac, Beiyang Wei, Len Neckers, William Stetler-Stevenson

Published Jan 27, 2013 · Vol. 4, No. 1 · pp. 163-173

Keywords: TIMP-2, microarray analysis, E-cadherin, cell adhesion, tumor growth inhibition

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Meiyun Fan, Susan R. Pfeffer, Henry T. Lynch, Pamela Cassidy, Sancy Leachman, Lawrence M. Pfeffer, Levy Kopelovich

Published Jan 19, 2013 · Vol. 4, No. 1 · pp. 128-141

Keywords: Familial Melanoma, gene expression, CDKN2A, p16, Mutations, Melanoma

Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts Research Paper

Anabel JosÃ©, Luciano Sobrevals, Juan Miguel Camacho-SÃ¡nchez, Meritxell Huch, NÃºria Andreu, Eduard Ayuso, Pilar Navarro, Ramon Alemany, Cristina Fillat

Published Jan 12, 2013 · Vol. 4, No. 1 · pp. 94-105

Keywords: Pancreatic cancer, adenovirus, orthotopic xenografts, transgenic mice, thymidine kinase

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper

Pooja Mohan, Joan Castellsague, Jihong Jiang, Kristi Allen, Helen Chen, Oksana Nemirovsky, Melanie Spyra, Kaiji Hu, Lan Kluwe, Miguel Angel Pujana, Alberto Villanueva, Victor F. Mautner, Jonathan J. Keats, Sandra E. Dunn, Conxi Lazaro, Christopher A. Maxwell

Published Jan 9, 2013 · Vol. 4, No. 1 · pp. 80-93

Keywords: Malignant peripheral nerve sheath tumors, Aurora kinase A, RHAMM, TPX2, cancer stem cell

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper

Published Dec 31, 2012 · Vol. 3, No. 12 · pp. 1700-1710

Keywords: DLBCL, gene expression profile, risk score, prognosis

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Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

CK2-NCoR signaling cascade promotes prostate tumorigenesis Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Necdin, a p53 target gene, in stem cells Editorial

Targeting HSF1 sensitizes cancer cells to HSP90 inhibition Research Paper

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

TAp73Î²-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics Research Paper

Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib Research Paper

DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis Research Paper

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts Research Paper

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemia Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

CK2-NCoR signaling cascade promotes prostate tumorigenesis Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Necdin, a p53 target gene, in stem cells Editorial

Targeting HSF1 sensitizes cancer cells to HSP90 inhibition Research Paper

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer Research Paper

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

TAp73Î²-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics Research Paper

Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib Research Paper

DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis Research Paper

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts Research Paper

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper

Gene expression-based risk score in diffuse large B-cell lymphoma Research Paper