The Oncosearch | Oncotarget

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

Tiago Baptista, InÃªs GraÃ§a, Elsa J Sousa, Ana I Oliveira, NatÃ¡lia R Costa, Pedro Costa-Pinheiro, Francisco Amado, Rui Henrique, Carmen Jeronimo

Published Aug 29, 2013 · Vol. 4, No. 10 · pp. 1673-1685

Keywords: Prostate cancer, H2A.Z, sirtuin 1, epigenetic drugs

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Wei Luo, Hu Qiang, Dan Wang, Kristin K Deeb, Yingyu Ma, Carl D Morrison, Song Liu, Candace S Johnson, Donald L Trump

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1472-1483

Keywords: Endothelial cell, Gene expression, DNA methylation, Prostate cancer

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Silvia Cufi, Bruna Corominas-Faja, Eugeni Lopez-Bonet, Rosa Bonavia, Sonia Pernas, Isabel Alvarez Lopez, Joan Dorca, Susana Martinez, Norberto Batista Lopez, Severina Dominguez Martinez, Elisabet Cuyas, Joana Visa, Esther Rodriguez-Gallego, Rosa Quirantes-Pine, Antonio Segura-Carretero, Jorge Joven, Begona Martin-Castillo, Javier A Menendez

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1484-1495

Keywords: Metformin, cancer, PI3K, PIK3CA mutations, dietary restriction, calorie restriction, rapamycin

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

Seok-Jun Kim, Jung-Ah Hwang, Jae Y. Ro, Yeon-Su Lee, Kyung-Hee Chun

Published Aug 20, 2013 · Vol. 4, No. 9 · pp. 1461-1471

Keywords: Galectin-7, Gastric cancer, DNA hypermethylation, Epigenetic mechanisms

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia Research Paper

Andrey Astori, Hanne Kristin Fredly, Thomas Aquinas Aloysius, Lars Bullinger, VÃ©ronique Mansat-De Mas, Pierre de la Grange, Francois Delhommeau, Karen Marie Hagen, Christian RÃ©cher, Isabelle Dusanter-Fourt, Stian Knappskog, Johan Richard Lillehaug, Frederic Pendino, Ã˜ystein Bruserud

Published Aug 15, 2013 · Vol. 4, No. 9 · pp. 1438-1448

Keywords: CXXC5, mRNA, acute myeloid leukemia, chemotherapy, apoptosis

Small-molecule targeting of translation initiation for cancer therapy Research Paper

Bertal H. Aktas, Yuan Qiao, Esra Ozdelen, Roland Schubert, Sema Sevinc, Fred Harbinski, Luciano Grubissich, Samuel Singer, Jose A. Halperin

Published Aug 14, 2013 · Vol. 4, No. 10 · pp. 1606-1617

Keywords: CANCER, TERNARY COMPLEX, TRANSLATION, eIF2, UTR

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Bailing Chen, Miaomiao Yu, Qingshan Chang, Yongju Lu, Chitra Thakur, Danjun Ma, Zhengping Yi, Fei Chen

Published Aug 10, 2013 · Vol. 4, No. 9 · pp. 1427-1437

Keywords: mdig, H19, demethylation, prognosis

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Shruti Desai, Minming Ding, Bin Wang, Zhimin Lu, Qi Zhao, Kenna Shaw, W K Alfred Yung, John N Weinstein, Ming Tan, Jun Yao

Published Aug 7, 2013 · Vol. 5, No. 18 · pp. 8202-8210

Keywords: PKM2, alternative splicing, DNA methylation

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Marianna L Ianzano, Stefania Croci, Giordano Nicoletti, Arianna Palladini, Lorena Landuzzi, Valentina Grosso, Dario Ranieri, Massimiliano Dall'Ora, Ilaria Santeramo, Milena Urbini, Carla De Giovanni, Pier Luigi Lollini, Patrizia Nanni

Published Aug 6, 2013 · Vol. 5, No. 1 · pp. 108-119

Keywords: rhabdomyosarcoma, p53, HER-2, p19Arf, p21Cip1

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

Raffaella Spina, Gessica Filocamo, Enrico Iaccino, Stefania Scicchitano, Michela Lupia, Emanuela Chiarella, Tiziana Mega, Francesca Bernaudo, Daniela Pelaggi, Maria Mesuraca, Simonetta Pazzaglia, Samantha Semenkow, Eli E Bar, Marcel Kool, Stefan Pfister, Heather M Bond, Charles G Eberhart, Christian SteinkÃ¼hler, Giovanni Morrone

Published Jul 27, 2013 · Vol. 4, No. 8 · pp. 1280-1292

Keywords: ZNF521, gene expression, medulloblastoma, cell growth, tumorigenicity, cancer stem cells

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

Jeff C. Liu, Sean E. Egan, Eldad Zacksenhaus

Published Jul 26, 2013 · Vol. 4, No. 8 · pp. 1317-1328

Keywords: Breast Cancer, HER2, prognostic signature, tumor-initiating cells

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Marc Delord, Philippe Rousselot, Jean-Michel Cayuela, FranÃ§ois Sigaux, JoÃ«lle Guilhot, Claude Preudhomme, FranÃ§ois Guilhot, Pascale Loiseau, Emmanuel Raffoux, Daniela Geromin, Emmanuelle Genin, Fabien Calvo, Heriberto Bruzzoni-Giovanelli

Published Jul 18, 2013 · Vol. 4, No. 10 · pp. 1582-1591

Keywords: CML, Imatinib, SNPs, ABCG2, Pharmacogenetic, molecular response, BCR-ABL

Clonogenic multiple myeloma cells have shared stemness signature associated with patient survival Research Paper

Renji Reghunathan, Chonglei Bi, Shaw Cheng Liu, Koh Tze Loong, Tae-Hoon Chung, Gaofeng Huang, Wee Joo Chng

Published Jul 15, 2013 · Vol. 4, No. 8 · pp. 1230-1240

Keywords: : myeloma, plasma cells, proliferation, differentiation, stemness

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Olga Ritz, Karolin Rommel, Karola Dorsch, Elena Kelsch, Julia Melzner, Michaela Buck, Karen Leroy, Vasiliki Papadopoulou, Simon Wagner, Jochen K Lennerz, Peter MÃ¶ller

Published Jul 13, 2013 · Vol. 4, No. 7 · pp. 1093-1102

Keywords: intratumoral heterogenity, PMBL, BCL6, pSTAT6

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper

Silvia Pegoraro, Gloria Ros, Silvano Piazza, Roberta Sommaggio, Yari Ciani, Antonio Rosato, Riccardo Sgarra, Giannino Del Sal, Guidalberto Manfioletti

Published Jul 9, 2013 · Vol. 4, No. 8 · pp. 1293-1308

Keywords: Epithelial to mesenchymal transition, stemness, HMGA1, breast cancer, invasion, metastasis, gene-signature

Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target Research Paper

Jun Huang, Sho Tabata, Soji Kakiuchi, Trung The Van, Hisatsugu Goto, Masaki Hanibuchi, Yasuhiko Nishioka

Published Jul 8, 2013 · Vol. 4, No. 8 · pp. 1172-1184

Keywords: malignant pleural mesothelioma, pregnancy-associated plasma protein A, migration, orthotopic xenograft mouse model

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

William J. Fredericks, Jorge Sepulveda, Priti Lal, John E. Tomaszewski, Ming-Fong Lin, Terry McGarvey, Frank J. Rauscher III, S. Bruce Malkowicz

Published Jul 7, 2013 · Vol. 4, No. 7 · pp. 1075-1092

Keywords: TERE1, UBIAD1, prostate cancer, castrate resistant prostate cancer, CRPC, LnCaP, cholesterol, SXR, androgen catabolism, Vitamin K-2

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program Research Paper

Xing-gang Mao, Marianne HÃ¼tt-Cabezas, Brent A. Orr, Melanie Weingart, Isabella Taylor, Anand K.D. Rajan, Yazmin Odia, Ulf Kahlert, Jarek Maciaczyk, Guido Nikkhah, Charles G. Eberhart, Eric H. Raabe

Published Jul 6, 2013 · Vol. 4, No. 7 · pp. 1050-1064

Keywords: brain tumor, invasion, HMGA2

Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer Research Paper

Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Wei Zhang, Jie Zhou, Gabriele DiSante, Zhiping Li, Hallgeir Rui, Andrew A. Quong, Steven B. McMahon, Haiteng Deng, Michael P. Lisanti, Chenguang Wang, Richard G. Pestell

Published Jun 21, 2013 · Vol. 4, No. 6 · pp. 923-935

Keywords: p53, breast cancer, cell fate, stem cells, dach

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Yunyun Jiang, Filip Janku, Vivek Subbiah, Laura S. Angelo, Aung Naing, Peter M. Anderson, Cynthia E. Herzog, Siqing Fu, Robert S. Benjamin, Razelle Kurzrock

Published Jun 5, 2013 · Vol. 4, No. 6 · pp. 884-889

Keywords: Ewing sarcoma, PTPRD, mutation, germline

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Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia Research Paper

Small-molecule targeting of translation initiation for cancer therapy Research Paper

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Clonogenic multiple myeloma cells have shared stemness signature associated with patient survival Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper

Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target Research Paper

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program Research Paper

Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia Research Paper

Small-molecule targeting of translation initiation for cancer therapy Research Paper

Mdig de-represses H19 large intergenic non-coding RNA (lincRNA) by down-regulating H3K9me3 and heterochromatin Research Paper

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Research Paper

A Tumor initiating cell-enriched prognostic signature for HER2+:ERÎ±- breast cancer; rationale, new features, controversies and future directions Research Perspective

High imatinib dose overcomes insufficient response associated with ABCG2 haplotype in chronic myelogenous leukemia patients Research Paper

Clonogenic multiple myeloma cells have shared stemness signature associated with patient survival Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness Research Paper

Identification of pregnancy-associated plasma protein A as a migration-promoting gene in malignant pleural mesothelioma cells: a potential therapeutic target Research Paper

The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes. Research Paper

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program Research Paper

Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper