The Oncosearch | Oncotarget

A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers Methodological Reports

Anita Lal, Rebecca Panos, Mira Marjanovic, Michael Walker, Eloisa Fuentes, Daniel S. Kapp, W David Henner, Ljubomir J. Buturovic, Meredith Halks-Miller

Published Feb 23, 2012 · Vol. 3, No. 2 · pp. 212-223

Keywords: gene expression, tissue of origin, endometrial cancer, ovarian cancer, diagnostic test

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

Nijiro Nohata, Toyoyuki Hanazawa, Hideki Enokida, Naohiko Seki

Published Feb 4, 2012 · Vol. 3, No. 1 · pp. 9-21

Keywords: cancer, miRNA, miR-1, miR-133a, miR-133b, miR-206

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Hideo Hidaka, Naohiko Seki, Hirofumi Yoshino, Takeshi Yamasaki, Yasutoshi Yamada, Nijiro Nohata, Miki Fuse, Masayuki Nakagawa, Hideki Enokida

Published Jan 30, 2012 · Vol. 3, No. 1 · pp. 44-57

Keywords: microRNA, expression signature, miR-1285, tumor suppressor, renal cell carcinoma, transglutaminase 2

Neoplastic cells are a rare component in human glioblastoma microvasculature Research Perspective

Fausto J. Rodriguez, Brent A. Orr, Keith L. Ligon, Charles G. Eberhart

Published Jan 30, 2012 · Vol. 3, No. 1 · pp. 98-106

Keywords: Glioblastoma, microvascular proliferation, endothelium, stem cells, FISH

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1) Research Paper

Nancy Liu-Sullivan, Jianping Zhang, Amy Bakleh, John Marchica, Jinyu Li, Despina Siolas, Sylvie Laquerre, Yan Y. Degenhardt, Richard Wooster, Kenneth Chang, Gregory J. Hannon, Scott Powers

Published Dec 30, 2011 · Vol. 2, No. 12 · pp. 1254-1264

Keywords: Polo-like kinase 1, shRNA library screening, retinoids, combination therapy strategies

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

Sharmin Esmailzadeh, Xiaoyan Jiang

Published Dec 30, 2011 · Vol. 2, No. 12 · pp. 918-934

Keywords: AHI-1, oncogene, CML, CTCL, AHI-1-BCR-ABL-JAK2 interaction complex, tyrosine kinase inhibitors, leukemic stem cells, TKI resistance

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

Paul M. Neilsen, Jacqueline E. Noll, Rachel J. Suetani, Renee B Schulz, Fares Al-Ejeh, Andreas Evdokiou, David P. Lane, David F. Callen

Published Dec 25, 2011 · Vol. 2, No. 12 · pp. 1203-1217

Keywords: mutant p53, p63, secretome, invasion

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Michal Sheffer, Amos J. Simon, Jasmine Jacob-Hirsch, Gideon Rechavi, Eytan Domany, David Givol, Gabriella D'Orazi

Published Dec 24, 2011 · Vol. 2, No. 12 · pp. 1191-1202

Keywords: hypoxia, cobalt, pathway analysis, Principal Component Analysis (PCA), cDNA microarray, colon cancer

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Paula Vainio, Laura Lehtinen, Tuomas Mirtti, Mika Hilvo, Tuulikki SeppÃ¤nen-Laakso, Johannes Virtanen, Anna Sankila, Stig Nordling, Johan Lundin, Antti Rannikko, Matej OreÅ¡iÄ, Olli Kallioniemi, Kristiina Iljin

Published Dec 22, 2011 · Vol. 2, No. 12 · pp. 1176-1190

Keywords: Prostate cancer, PLA2G7, drug target, biomarker, statins

PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells Research Paper

Allan Siu, Carl Virtanen, Jan Jongstra

Published Dec 21, 2011 · Vol. 2, No. 12 · pp. 1134-1144

Keywords: M-110, PIM kinase, MIG6, EGFR, Gefitinib, Prostate Cancer

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients Brief Reports

Netta MÃ¤kinen, Hanna-Riikka Heinonen, Shane Moore, Ian Tomlinson, Zephne van der Spuy, Lauri Aaltonen

Published Dec 19, 2011 · Vol. 2, No. 12 · pp. 966-969

Keywords: uterine leiomyoma, fibroid, MED12, ethnicity

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Dannis Gilbert Van Vuurden, Esther Hulleman, Olga L.M. Meijer, Laurine E. Wedekind, Marcel Kool, Hendrik Witt, W. Peter Vandertop, Thomas WÃ¼rdinger, David P. Noske, Gertjan J.L. Kaspers, Jacqueline Cloos

Published Dec 15, 2011 · Vol. 2, No. 12 · pp. 984-996

Keywords: PARP, radiation, medulloblastoma, ependymoma, glioma, pediatric

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

Wanglong Qiu, Fikret Sahin, Christine Iacobuzio-Donahue, Dario Garcia-Carracedo, Wendy Wang, Chia-Yu Kuo, Doris Chen, Dan Arking, Andrew Lowy, Ralph Hruban, Helen Remotti, Gloria H. Su

Published Nov 23, 2011 · Vol. 2, No. 11 · pp. 862-873

Keywords: p16, LOH at Kras, pancreatic cancer, metastasis, mouse model, conditional knock-out, target therapy, PanIN, Pancreatic ductal adenocarcinoma, tumor-suppressor gene.

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Hong Zhao, Jian wang, Yongqing Han, Zhen Huang, Jianming Ying, Xinyu Bi, Jianjun Zhao, Yi Fang, Haitao Zhou, Jianguo Zhou, Zhiyu Li, Yefan Zhang, Xue Yang, Tao Yan, Linfang Wang, Michael S Torbenson, Jianqiang Cai

Published Nov 16, 2011 · Vol. 2, No. 11 · pp. 886-891

Keywords: Hepatocellular Carcinoma, Hepatitis C Virus, ARID2, Tumor Suppressor, Interferon

PinX1: a sought-after major tumor suppressor at human chromosome 8p23 Research Perspective

Xiao Zhen Zhou

Published Oct 20, 2011 · Vol. 2, No. 10 · pp. 810-819

Keywords: Tumor suppressor, telomerase inhibitor, PinX1, chromosome instabilty, 8p23, LOH

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells Research Paper

Henry Garcia, Daria Fleyshman, Kateryna Kolesnikova, Alfiya Safina, Mairead Commane, Geraldine Paszkiewicz, Angela Omelian, Carl Morrison, Katerina Gurova

Published Oct 13, 2011 · Vol. 2, No. 10 · pp. 783-796

Keywords: Key words: chromatin remodeling, transcription, SPT16, SSRP1, cancer, differentiation, proliferation, oncotarget

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Cheryl M. Koh, Tsuyoshi Iwata, Qizhi Zheng, Carlise Bethel, Srinivasan Yegnasubramanian, Angelo M. De Marzo

Published Sep 19, 2011 · Vol. 2, No. 9 · pp. 669-683

Keywords: Myc, EZH2, prostate cancer

Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis Research Perspective

Margit Rosner, Helmut Dolznig, Katharina Schipany, Mario Mikula, Oliver Brandau, Markus HengstschlÃ¤ger

Published Sep 14, 2011 · Vol. 2, No. 9 · pp. 705-712

Keywords: stem cells, human genetics, oncogenesis, amniocentesis, RNA interference, mTOR

NUAK2: an emerging acral melanoma oncogene Research Perspective

Takeshi Namiki, Sergio G. Coelho, Vincent J. Hearing

Published Sep 10, 2011 · Vol. 2, No. 9 · pp. 695-704

Keywords: NUAK2, acral melanoma, migration, metastasis, oncogene

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective

Lorena Nogueira, Patricia Ruiz-OntaÃ±on, Alfonso Vazquez-Barquero, Francisco Moris, Jose L. Fernandez-Luna

Published Sep 5, 2011 · Vol. 2, No. 8 · pp. 646-653

Keywords: NFÎºB, glioblastoma, senescence, IKK inhibitor

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A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers Methodological Reports

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Neoplastic cells are a rare component in human glioblastoma microvasculature Research Perspective

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1) Research Paper

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells Research Paper

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients Brief Reports

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

PinX1: a sought-after major tumor suppressor at human chromosome 8p23 Research Perspective

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells Research Paper

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis Research Perspective

NUAK2: an emerging acral melanoma oncogene Research Perspective

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers Methodological Reports

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers Review

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Neoplastic cells are a rare component in human glioblastoma microvasculature Research Perspective

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1) Research Paper

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells Research Paper

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients Brief Reports

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

PinX1: a sought-after major tumor suppressor at human chromosome 8p23 Research Perspective

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells Research Paper

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis Research Perspective

NUAK2: an emerging acral melanoma oncogene Research Perspective

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective