The Oncosearch | Oncotarget

Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis Research Paper

Alejandra M. Petrilli, Marga Bott, Cristina FernÃ¡ndez-Valle

Published Nov 15, 2013 · Vol. 4, No. 12 · pp. 2354-2365

Keywords: Neurofibromatosis Type 2, SIRT2, tumor suppressor

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Changcun Guo, Lee H. Chen, Yafen Huang, Chun-Chi Chang, Ping Wang, Christopher J. Pirozzi, Xiaoxia Qin, Xuhui Bao, Paula K. Greer, Roger E. McLendon, Hai Yan, Stephen T. Keir, Darell D. Bigner, Yiping He

Published Nov 3, 2013 · Vol. 4, No. 11 · pp. 2144-2153

Keywords: MLL2, isogenic cell line, gene knockout, enhancer

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

Hao Zhang, Wan Lin, Kalpana Kannan, Liming Luo, Jing Li, Pei-Wen Chao, Yan Wang, Yu-Ping Chen, Jiang Gu, Laising Yen

Published Nov 1, 2013 · Vol. 4, No. 11 · pp. 2135-2143

Keywords: Transcriptome, transcription-induced chimeric RNAs, GOLM1-MAK10, secreted fusion protein, cancer biomarker, esophageal cancer

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

He Shen, Carl D. Morrison, Jianmin Zhang, Willie Underwood III, Nuo Yang, Costa Frangou, Kevin Eng, Karen Head, Roni J. Bollag, Sravan K. Kavuri, Amyn M. Rojiani, Yingwei Li, Li Yan, Annette Hill, Anna Woloszynska-Read, Jianmin Wang, Song Liu, Donald L. Trump, Candace S. Johnson

Published Oct 29, 2013 · Vol. 4, No. 11 · pp. 2124-2134

Keywords: bladder cancer, chromosome 6p22, FISH, outcome, survival

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai P. Mohammad, Xiaoyu Pan, Frank Vendetti, Wim VanCriekinge, Tim DeMeyer, Zhengzong Du, Princy Parsana, Kristen Rodgers, Ray-Whay Yen, Cynthia A. Zahnow, Janis M. Taube, Julie R. Brahmer, Scott S. Tykodi, Keith Easton, Richard D. Carvajal, Peter A. Jones, Peter W. Laird, Daniel J. Weisenberger, Salina Tsai, Rosalyn A. Juergens, Suzanne L. Topalian, Charles M. Rudin, Malcolm V. Brock, Drew Pardoll, Stephen B. Baylin

Published Oct 25, 2013 · Vol. 4, No. 11 · pp. 2067-2079

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

In-Kyu Kim, Sun-Mi Park, Hee Jun Cho, Kyoung Eun Baek, In-Koo Nam, Seung-Ho Park, Ki-Jun Ryu, Jinhyun Ryu, Jungil Choi, Soon-Chan Hong, Jae Won Kim, Chang Won Lee, Sang Soo Kang, Jiyun Yoo

Published Oct 19, 2013 · Vol. 4, No. 11 · pp. 2045-2056

Keywords: RhoGDI2, 14-3-3Ïƒ, gastric cancer, chemoresistance, metastasis

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe'er, Mina J. Bissell, Ren Xu

Published Oct 14, 2013 · Vol. 4, No. 11 · pp. 2010-2020

Keywords: disorganization gene signature, p65, RelB, three-dimensional tissue structure, tissue polarity

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Ilaria Sciamanna, Alberto Gualtieri, Cristina Cossetti, Emanuele Felice Osimo, Manuela Ferracin, Gianfranco Macchia, Eleonora Arico, Gianni Prosseda, Patrizia Vitullo, Tom Misteli, Corrado Spadafora

Published Oct 14, 2013 · Vol. 4, No. 12 · pp. 2271-2287

Keywords: LINE-1 retrotransposons, reverse transcriptase, transcriptome, miRNAs, DNA:RNA hybrids, cancer genome, reverse transcriptase inhibitor.

Lysine-specific modifications of p53: a matter of life and death? Review

Diana Marouco, Alexander V Garabadgiu, Gerry Melino, Nick A Barlev

Published Oct 8, 2013 · Vol. 4, No. 10 · pp. 1556-1571

Keywords: p53, post-translational modifications, lysine methylation, acetylation

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Hyesoon Kim, Seung-Hwan Lee, Mi-Ni Lee, Goo Taeg Oh, Kyung-Chul Choi, Eun Young Choi

Published Oct 3, 2013 · Vol. 4, No. 11 · pp. 1976-1985

Keywords: p53, inflammation, endothelial cell, Del-1

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Hanna Ning, Hiroshi Mitsui, Claire Q.F. Wang, Mayte SuÃ¡rez-FariÃ±as, Juana Gonzalez, Kejal R. Shah, Jie Chen, Israel Coats, Diane Felsen, John A. Carucci, James G. Krueger

Published Oct 2, 2013 · Vol. 4, No. 12 · pp. 2237-2248

Keywords: oncotarget, basal cell carcinoma, anaplastic lymphoma kinase, laser capture microdissection

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Xiaoping Wu, Huixian Huang, Cong Wang, Shaoqiang Lin, Yadong Huang, Yi Wang, Guang Liang, Qiuxia Yan, Jian Xiao, Jianzhang Wu, Yongguang Yang, Xiaokun Li

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1819-1828

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Seung-Hyun Hong, Sung-Ho Goh, Sang-Jin Lee, Jung-Ah Hwang, Jieun Lee, Il-Ju Choi, Hyehyun Seo, Jong-Hoon Park, Hiromu Suzuki, Eiichiro Yamamoto, In-Hoo Kim, Jin Sook Jeong, Mi Ha Ju, Dong-Hee Lee, Yeon-Su Lee

Published Sep 30, 2013 · Vol. 4, No. 10 · pp. 1791-1803

Keywords: gastric cancer, adenylate cyclase, tumorigenesis, cAMP/PKA/CREB pathway, promoter methylation

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Julia M. Fraile, Gonzalo R. OrdoÃ±ez, Pedro M. Quiros, Aurora Astudillo, Jose A. Galvan, Dolors Colomer, Carlos Lopez-Otin, Jose M.P. Freije, Xose S. Puente

Published Sep 15, 2013 · Vol. 4, No. 11 · pp. 1919-1932

Keywords: proteolysis, metastasis, invasion, cancer

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Andrea Treszl, Zita Steiber, Andrew V Schally, Norman L Block, Balazs Dezso, Gabor Olah, Bernadett Rozsa, Klara Fodor, Armin Buglyo, Janos Gardi, Andras Berta, Gabor Halmos

Published Sep 10, 2013 · Vol. 4, No. 10 · pp. 1721-1728

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Riccardo Masetti, Marco Togni, Annalisa Astolfi, Martina Pigazzi, Elena Manara, Valentina Indio, Carmelo Rizzari, Sergio Rutella, Giuseppe Basso, Andrea Pession, Franco Locatelli

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1712-1720

Keywords: pediatric acute myeloid leukemia, citogenetically normal acute myeloid leuekemia, whole-transcriptome massively parallel sequencing, CBFA2T3-GLIS2 fusion transcript, DHH-RHEBL1 fusion transcript.

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

Daniela Loetsch, Elisabeth Steiner, Klaus Holzmann, Sabine Spiegl-Kreinecker, Christine Pirker, Juraj Hlavaty, Helga Petznek, Balazs Hegedus, Tamas Garay, Thomas Mohr, Wolfgang Sommergruber, Walter Berger, Michael Grusch

Published Sep 1, 2013 · Vol. 4, No. 11 · pp. 1904-1918

Keywords: major vault protein, vault particles, glioblastoma multiforme, EGFR, PI3K, migration, invasion

TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth Research Paper

Sam Mattiske, Kristen Ho, Jacqueline E. Noll, Paul M. Neilsen, David F. Callen, Rachel J. Suetani

Published Aug 31, 2013 · Vol. 4, No. 11 · pp. 1894-1903

Keywords: miR-155, TAp63, Î”Np63, cancer, tumorigenesis, migration

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper

Jing Liu, Zhijie Xiao, Sunny Kit-Man Wong, Vicky Pui-Chi Tin, Ka-Yan Ho, Junwen Wang, Mai-Har Sham, Maria Pik Wong

Published Aug 30, 2013 · Vol. 4, No. 10 · pp. 1698-1711

Keywords: lung cancer, tumor initiating cell, aldehyde dehydrogenase, CD44, drug resistance

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Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis Research Paper

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Lysine-specific modifications of p53: a matter of life and death? Review

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis Research Paper

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines Research Paper

Lysine-specific modifications of p53: a matter of life and death? Review

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis Research Paper

TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDHhi CD44hi tumor initiating cells Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper