The Oncosearch | Oncotarget

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Bo Cao, Yanfeng Qi, Guanyi Zhang, Duo Xu, Yang Zhan, Xavier Alvarez, Zhiyong Guo, Xueqi Fu, Stephen R. Plymate, Oliver Sartor, Haitao Zhang, Yan Dong

Published Mar 4, 2014 · Vol. 5, No. 6 · pp. 1646-1656

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

Da Li, Fang-Fang Bi, Na-Na Chen, Ji-Min Cao, Wu-Ping Sun, Yi-Ming Zhou, Chen Cao, Chun-Yan Li, Qing Yang

Published Feb 27, 2014 · Vol. 5, No. 5 · pp. 1315-1325

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

Alboukadel Kassambara, Claire Gourzones-Dmitriev, Surinder Sahota, Thierry RÃ¨me, JÃ©rÃ´me Moreaux, Hartmut Goldschmidt, Angelos Constantinou, Phillipe Pasero, Dirk Hose, Bernard Klein

Published Feb 24, 2014 · Vol. 5, No. 9 · pp. 2487-2498

Keywords: DNA repair, Multiple Myeloma, prognosis

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

Steffen Ormanns, Jens Neumann, David Horst, Thomas Kirchner, Andreas Jung

Published Feb 19, 2014 · Vol. 5, No. 10 · pp. 2999-3011

Keywords: WNT, Î²-Catenin, PI3K, colon cancer, metastasis

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Yan Cao, Yan Xu, Lei Zhang, Zhen Li, Ying Jiang, Xiao Tian, Andrei Seluanov, Vera Gorbunova, Zhiyong Mao

Published Feb 19, 2014 · Vol. 5, No. 7 · pp. 1805-1811

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

Rivki Cashman, Helit Cohen, Rotem Ben-Hamo, Alona Zilberberg, Sol Efroni

Published Feb 18, 2014 · Vol. 5, No. 4 · pp. 1071-1082

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Andrew E. Tee, Dora Ling, Charlotte Nelson, Bernard Atmadibrata, Marcel E. Dinger, Ning Xu, Tamio Mizukami, Pei Y. Liu, Bing Liu, Belamy Cheung, Eddy Pasquier, Michelle Haber, Murray D. Norris, Takayoshi Suzuki, Glenn M. Marshall, Tao Liu

Published Feb 18, 2014 · Vol. 5, No. 7 · pp. 1793-1804

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

Huili Li, Katherine B. Chiappinelli, Angela A. Guzzetta, Hariharan Easwaran, Ray-Whay Chiu Yen, Rajita Vatapalli, Michael J. Topper, Jianjun Luo, Roisin M. Connolly, Nilofer S. Azad, Vered Stearns, Drew M. Pardoll, Nancy Davidson, Peter A. Jones, Dennis J. Slamon, Stephen B. Baylin, Cynthia A. Zahnow, Nita Ahuja

Published Feb 16, 2014 · Vol. 5, No. 3 · pp. 587-598

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells Research Paper

Almudena Bosch, Konstantina Panoutsopoulou, Josep Maria Corominas, RamÃ³n Gimeno, Gema Moreno-Bueno, Juan MartÃn-Caballero, Saleta Morales, Tania Lobato, Carles MartÃnez-Romero, Eduardo F. Farias, Xavier Mayol, Amparo Cano, Inmaculada HernÃ¡ndez-MuÃ±oz

Published Feb 14, 2014 · Vol. 5, No. 8 · pp. 2065-2076

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Esa PitkÃ¤nen, Tatiana Cajuso, Riku Katainen, Eevi Kaasinen, Niko VÃ¤limÃ¤ki, Kimmo Palin, Jussi Taipale, Lauri A. Aaltonen, Outi Kilpivaara

Published Feb 14, 2014 · Vol. 5, No. 3 · pp. 853-859

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Zenobia C. D'Costa, Catherine A. Higgins, Chee Wee Ong, Gareth Irwin, David Boyle, Darragh G. McArt, Karen McCloskey, Niamh E. Buckley, Nyree T. Crawford, Lalitha Thiagarajan, James T. Murray, Richard D. Kennedy, Karl A. Mulligan, Denis P. Harkin, David J.J. Waugh, Chris J. Scott, Manuel Salto-Tellez, Richard Williams, Paul B. Mullan

Published Feb 8, 2014 · Vol. 5, No. 6 · pp. 1609-1620

Keywords: TBX2, CST6, LGMN, breast cancer

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene Research Paper

Erling A. Hoivik, Kanthida Kusonmano, Mari K. Halle, Anna Berg, Elisabeth Wik, Henrica M. J. Werner, Kjell Petersen, Anne M. Oyan, Karl-Henning Kalland, Camilla Krakstad, Jone Trovik, Martin Widschwendter, Helga B. Salvesen

Published Jan 28, 2014 · Vol. 5, No. 4 · pp. 1052-1061

Keywords: CTCFL/BORIS, endometrial cancer, Epi-driver gene, recurrence, metastasis

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Arnau Montraveta, Silvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Laia Rosich, Patricia PÃ©rez-GalÃ¡n, Itziar Salaverria, Silvia BeÃ, Susana G. Kalko, MercÃ¨ de Frias, Clara CampÃ s, GaÃ«l RouÃ©, Dolors Colomer

Published Jan 25, 2014 · Vol. 5, No. 3 · pp. 726-739

Keywords: Acadesine, rituximab, mantle cell lymphoma, xenograft mouse model

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cecile Pautas, Remy Dulery, Thomas Boyer, Jean-Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, Hassan Farhat, Nicolas Boissel, Christine Terre, Herve Dombret, Sylvie Castaigne, Claude Preudhomme

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 916-932

Keywords: acute myeloid leukemia, SNP array lesions, gene mutations, gemtuzumab ozogamicin, prognosis

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

Marcella Salzano, Marta VÃ¡zquez-Cedeira, Marta Sanz-GarcÃa, Alberto Valbuena, Sandra Blanco, Isabel F. FernÃ¡ndez, Pedro A. Lazo

Published Jan 17, 2014 · Vol. 5, No. 7 · pp. 1770-1778

Keywords: Breast cancer, VRK1, Radiation, doxorubicin, chemotherapy, DNA damage, 53BP1

NF-ÎºB1 inhibits c-Myc protein degradation through suppression of FBW7 expression Research Paper

Haishan Huang, Li Ma, Jingxia Li, Yonghui Yu, Dongyun Zhang, Jinlong Wei, Honglei Jin, Derek Xu, Jinmin Gao, Chuanshu Huang

Published Jan 15, 2014 · Vol. 5, No. 2 · pp. 493-505

Keywords: NF-ÎºB p50, arsenite, c-Myc, protein degradation, FBW7

GATA2 as a potential metastasis-driving gene in prostate cancer Research Paper

Yan Ting Chiang, Kendric Wang, Ladan Fazli, Robert Z. Qi, Martin E. Gleave, Colin C. Collins, Peter W. Gout, Yuzhuo Wang

Published Jan 12, 2014 · Vol. 5, No. 2 · pp. 451-461

Keywords: GATA2 gene, prostate cancer, metastasis, focal adhesion, master regulatory gene

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper

Justina McEvoy, Panduka Nagahawatte, David Finkelstein, Jennifer Richards-Yutz, Marcus Valentine, Jing Ma, Charles Mullighan, Guangchun Song, Xiang Chen, Matthew Wilson, Rachel Brennan, Stanely Pounds, Jared Becksfort, Robert Huether, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, David J. Dooling, Kerri Ochoa, Elaine R. Mardis, Richard K. Wilson, John Easton, Jinghui Zhang, James R. Downing, Arupa Ganguly, Michael A. Dyer

Published Jan 11, 2014 · Vol. 5, No. 2 · pp. 438-450

Keywords: chromothripsis, retinoblastoma, RB1, MYCN

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Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

NF-ÎºB1 inhibits c-Myc protein degradation through suppression of FBW7 expression Research Paper

GATA2 as a potential metastasis-driving gene in prostate cancer Research Paper

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers Priority Research Paper

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial Research Paper

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response Research Paper

NF-ÎºB1 inhibits c-Myc protein degradation through suppression of FBW7 expression Research Paper

GATA2 as a potential metastasis-driving gene in prostate cancer Research Paper

RB1 gene inactivation by chromothripsis in human retinoblastoma Research Paper