The Oncosearch | Oncotarget

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Rosaria ChilÃ, Alessandra Basana, Monica Lupi, Federica Guffanti, Eugenio Gaudio, Andrea Rinaldi, Luciano Cascione, Valentina Restelli, Chiara Tarantelli, Francesco Bertoni, Giovanna Damia, Laura Carrassa

Published Oct 25, 2014 · Vol. 6, No. 5 · pp. 3394-3408

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Annat Raiter, Rinat Yerushalmi, Britta Hardy

Published Oct 24, 2014 · Vol. 5, No. 22 · pp. 11452-11463

Keywords: triple negative breast cancer cells, drug induced cell surface GRP78, apoptosis

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

Tsai-Hsien Hung, Sheng-Chi Hsu, Ching-Yi Cheng, Kong-Bung Choo, Ching-Ping Tseng, Tse-Ching Chen, Ying-Wei Lan, Tsung-Teng Huang, Hsin-Chih Lai, Chuan-Mu Chen, Kowit-Yu Chong

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12273-12290

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

David S. Hong, Razelle Kurzrock, Marilyn Mulay, Erik Rasmussen, Benjamin M. Wu, Michael B. Bass, Zhandong D. Zhong, Greg Friberg, Lee S. Rosen

Published Oct 23, 2014 · Vol. 5, No. 22 · pp. 11154-11167

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Eftychia Oikonomou, Evangelos Koustas, Maria Goulielmaki, Alexander Pintzas

Published Oct 21, 2014 · Vol. 5, No. 23 · pp. 11752-11777

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette, Ugra S. Singh

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11709-11722

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Wynand P. Roos, Steve Quiros, Andrea Krumm, Stephanie Merz, Olivier JÃ©rÃ´me Switzeny, Markus Christmann, Carmen Loquai, Bernd Kaina

Published Oct 21, 2014 · Vol. 5, No. 24 · pp. 12607-12620

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current Research Paper

Marta Gritti, Roberto WÃ¼rth, Marina Angelini, Federica Barbieri, Marta Peretti, Erika Pizzi, Alessandra Pattarozzi, Elisa Carra, Rodolfo Sirito, Antonio Daga, Paul M.G. Curmi, Michele Mazzanti, Tullio Florio

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11252-11268

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells Research Paper

Sajjeev Jaganathan, Ehsan Malek, Subrahmanya Vallabhapurapu, Sivakumar Vallabhapurapu, James J. Driscoll

Published Oct 18, 2014 · Vol. 5, No. 23 · pp. 12358-12370

Keywords: Myeloma, Proteasome, Drug Resistance, Autophagy, Apoptosis

Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters Research Paper

Qiong Wu, Zhiping Yang, Lin Xia, Yongzhan Nie, Kaichun Wu, Yongquan Shi, Daiming Fan

Published Oct 18, 2014 · Vol. 5, No. 22 · pp. 11552-11563

AXL kinase as a novel target for cancer therapy Review

Xiaoliang Wu, Xuewen Liu, Sanjay Koul, Chang Youl Lee, Zhenfeng Zhang, Balazs Halmos

Published Oct 16, 2014 · Vol. 5, No. 20 · pp. 9546-9563

Keywords: AXL, receptor tyrosine kinase, lung cancer, targeted therapy

Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils Research Paper

CÃ©dric Seignez, Amandine Martin, Claire-Emmanuelle Rollet, Cindy Racoeur, Alessandra Scagliarini, Jean-FranÃ§ois Jeannin, Ali Bettaieb, Catherine Paul

Published Oct 16, 2014 · Vol. 5, No. 22 · pp. 11442-11451

Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition Research Paper

Hiroki Tamaki, Nanae Harashima, Miho Hiraki, Naoko Arichi, Nobuhiro Nishimura, Hiroaki Shiina, Kohji Naora, Mamoru Harada

Published Oct 15, 2014 · Vol. 5, No. 22 · pp. 11399-11412

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

Angelika Berger, Veronika Sexl, Peter Valent, Richard Moriggl

Published Oct 9, 2014 · Vol. 5, No. 20 · pp. 9564-9576

Keywords: STAT5, BCR-ABL1, tyrosine kinase, leukemia, inhibitors, SH2 domain, GTPases, nuclear translocation

A novel drug discovery strategy: Mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-ÎºB pathways Research Paper

Chunlin Zhuang, Chunquan Sheng, Woo Shik Shin, Yuelin Wu, Jin Li, Jianzhong Yao, Guoqiang Dong, Wen Zhang, Yuk Yin Sham, Zhenyuan Miao, Wannian Zhang

Published Oct 7, 2014 · Vol. 5, No. 21 · pp. 10830-10839

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

Kit Man Chai, Chih-Yen Wang, Hung-Jiun Liaw, Kuan-Min Fang, Chung-Shi Yang, Shun-Fen Tzeng

Published Oct 7, 2014 · Vol. 5, No. 21 · pp. 10901-10915

Keywords: BRCC3, BRCC36, ï§H2AX, DNA repair, Glioblastoma

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Mi Kwon Son, Sun-Mi Yun, Sung-Hoon Ahn, Kyeong-Ryoon Lee, Soyoung Lee, Donghee Kim, Sungwoo Hong, Soon-Sun Hong

Published Sep 29, 2014 · Vol. 5, No. 20 · pp. 10180-10197

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

Ehsan Malek, Sajjeev Jagannathan, James J. Driscoll

Published Sep 29, 2014 · Vol. 5, No. 18 · pp. 8027-8038

Keywords: non-coding RNAs, long-non-coding RNAs, microRNAs, HOTAIR, overall survival

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Xiaodong Zhou, Ling Shen, Toshima Parris, Junchi Huang, Bo Yi, Khalil Helou, Changyan Chen

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10709-10717

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper

Xiang Wang, Xi Zhang, Ben-shang Li, Xiaowen Zhai, Zhuo Yang, Li-xia Ding, Hongsheng Wang, Chris Liang, Weiliang Zhu, Jian Ding, Ling-hua Meng

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10732-10744

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Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current Research Paper

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells Research Paper

Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters Research Paper

AXL kinase as a novel target for cancer therapy Review

Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils Research Paper

Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition Research Paper

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

A novel drug discovery strategy: Mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-ÎºB pathways Research Paper

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells Research Paper

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current Research Paper

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells Research Paper

Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters Research Paper

AXL kinase as a novel target for cancer therapy Review

Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils Research Paper

Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition Research Paper

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

A novel drug discovery strategy: Mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-ÎºB pathways Research Paper

Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Research Paper

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer Review

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper