The Oncosearch | Oncotarget

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

He Wang, Henghui Yin, Fengjiao Yan, Mingna Sun, Lingran Du, Wei Peng, Qiuli Li, Yinghong Feng, Yi Zhou

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2827-2842

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Arjun Kalvala, Li Gao, Brittany Aguila, Tyler Reese, Gregory A. Otterson, Miguel A. Villalona-Calero, Wenrui Duan

Published Dec 30, 2014 · Vol. 6, No. 11 · pp. 8777-8787

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Afua Adjeiwaa Mensah, Ivo Kwee, Eugenio Gaudio, Andrea Rinaldi, Maurilio Ponzoni, Luciano Cascione, Gianluca Fossati, Anastasios Stathis, Emanuele Zucca, Gianluca Caprini, Francesco Bertoni

Published Dec 30, 2014 · Vol. 6, No. 7 · pp. 5059-5071

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Anastassia Serguienko, Iwona Grad, Anna B. WennerstrÃ¸m, Leonardo A. Meza-Zepeda, Bernd Thiede, Eva W. Stratford, Ola Myklebost, Else Munthe

Published Dec 29, 2014 · Vol. 6, No. 4 · pp. 2451-2465

NCL1, a highly selective lysine-specific demethylase 1 inhibitor, suppresses prostate cancer without adverse effect Research Paper

Toshiki Etani, Takayoshi Suzuki, Taku Naiki, Aya Naiki-Ito, Ryosuke Ando, Keitaro Iida, Noriyasu Kawai, Keiichi Tozawa, Naoki Miyata, Kenjiro Kohri, Satoru Takahashi

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2865-2878

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Wafa Hassen, Alboukadel Kassambara, Thierry Reme, Surinder Sahota, Anja Seckinger, Laure Vincent, Guillaume Cartron, JÃ©rÃ´me Moreaux, Dirk Hose, Bernard Klein

Published Dec 26, 2014 · Vol. 6, No. 8 · pp. 6431-6447

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

Mohamed A.Y. Abdel Malek, Sajjeev Jagannathan, Ehsan Malek, Douaa M. Sayed, Sahar A. Elgammal, Hanan G. Abd El-Azeem, Nabila M. Thabet, James J. Driscoll

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3098-3110

MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A Research Paper

Katsuya Ohta, Hiromitsu Hoshino, Jinhua Wang, Shigeshi Ono, Yuuki Iida, Keisuke Hata, Sharon K. Huang, Steven Colquhoun, Dave S. B. Hoon

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3211-3224

MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells Research Paper

Ji-Su Mo, Khondoker Jahengir Alam, In-Hong Kang, Won Cheol Park, Geom-Seog Seo, Suck-Chei Choi, Hun-Soo Kim, Hyung-Bae Moon, Ki-Jung Yun, Soo-Cheon Chae

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2843-2855

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Youhong Liu, Lin Chen, Zhicheng Gong, Liangfang Shen, Chinghai Kao, Janet M. Hock, Lunquan Sun, Xiong Li

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3055-3070

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia Research Paper

Sabine Cerny-Reiterer, Anja Rabenhorst, Gabriele Stefanzl, Susanne Herndlhofer, Gregor Hoermann, Leonhard MÃ¼llauer, Sigrid Baumgartner, Christine Beham-Schmid, Wolfgang R. Sperr, Christine Mannhalter, Heinz Sill, Werner Linkesch, Michel Arock, Karin Hartmann, Peter Valent

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3071-3084

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Loredana Vesci, Elena Bernasconi, Ferdinando Maria Milazzo, Rita De Santis, Eugenio Gaudio, Ivo Kwee, Andrea Rinaldi, Silvia Pace, Valeria Carollo, Giuseppe Giannini, Francesco Bertoni

Published Dec 25, 2014 · Vol. 6, No. 8 · pp. 5735-5748

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

Published Dec 19, 2014 · Vol. 5, No. 23 · pp. 11847-11856

Keywords: colorectal cancer, heregulin, resistance, cetuximab, patritumab

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

Antonella Cusimano, Roberto Puleio, Natale D'Alessandro, Guido R. Loria, James A. McCubrey, Giuseppe Montalto, Melchiorre Cervello

Published Dec 19, 2014 · Vol. 6, No. 3 · pp. 1707-1722

Keywords: HCC, AKT, mTOR, SC66, anoikis.

Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Jing Zhao, Yibing Huang, Dong Liu, Yuxin Chen

Published Dec 19, 2014 · Vol. 6, No. 3 · pp. 1769-1778

Keywords: Anticancer peptides, doxorubicin/epirubicin, synergy, mechanism of action, xenograft model

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Xiao Xiao, Zhiguo Liu, Rui Wang, Jiayin Wang, Song Zhang, Xiqiang Cai, Kaichun Wu, Raymond C. Bergan, Li Xu, Daiming Fan

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3225-3239

Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma Research Paper

Xingming Jiang, Ning Ma, Dayong Wang, Fuyuan Li, Rongzhang He, Dongliang Li, Ruiqi Zhao, Qingxin Zhou, Yimin Wang, Fumin Zhang, Ming Wan, Pengcheng Kang, Xu Gao, Yunfu Cui

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3178-3194

Classification of current anticancer immunotherapies Review

Lorenzo Galluzzi, Erika Vacchelli, JosÃ©-Manuel Bravo-San Pedro, Aitziber BuquÃ©, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka FuÄÃkovÃ¡, Dmitry I. Gabrilovich, JÃ©rÃ´me Galon, Abhishek Garg, FranÃ§ois Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk JÃ¤ger, Pawel Kalinski, Klas KÃ¤rre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine SautÃ¨s-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, BenoÃ®t J. Van Den Eynde, Richard Vile, Hermann Wagner, JeffreyÂ S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12472-12508

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Yu Fujita, Shigehiro Yagishita, Fumitaka Takeshita, Yusuke Yamamoto, Kazuyoshi Kuwano, Takahiro Ochiya

Published Dec 17, 2014 · Vol. 6, No. 5 · pp. 3335-3345

Keywords: RPN2, NSCLC, RNAi, siRNA, malignancy

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Guobing Li, Jing Zhou, Amit Budhraja, Xiaoye Hu, Yibiao Chen, Qi Cheng, Lei Liu, Ting Zhou, Ping Li, Ehu Liu, Ning Gao

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1834-1849

Keywords: Cofilin, Drp1, mitochondrial fission, erucin, apoptosis

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Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

NCL1, a highly selective lysine-specific demethylase 1 inhibitor, suppresses prostate cancer without adverse effect Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A Research Paper

MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma Research Paper

Classification of current anticancer immunotherapies Review

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

NCL1, a highly selective lysine-specific demethylase 1 inhibitor, suppresses prostate cancer without adverse effect Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A Research Paper

MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells Research Paper

Two hits are better than one: synergistic anticancer activity of Î±-helical peptides and doxorubicin/epirubicin Research Paper

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis Research Paper

Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma Research Paper

Classification of current anticancer immunotherapies Review

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis Research Paper