The Oncosearch | Oncotarget

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Shachar Raz, Michal Stark, Yehuda G. Assaraf

Published Aug 27, 2014 · Vol. 5, No. 19 · pp. 9183-9198

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Shalana Oâ€™Brien, Vita M. Golubovskaya, Jeffrey Conroy, Song Liu, Dan Wang, Biao Liu, William G. Cance

Published Aug 25, 2014 · Vol. 5, No. 17 · pp. 7945-7959

Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer Research Paper

Hong Hua Yan, Kyung Hee Jung, Mi Kwon Son, Zhenghuan Fang, Soo Jung Kim, Ye-Lim Ryu, Juyoung Kim, Mi-Hyun Kim, Soon-Sun Hong

Published Aug 23, 2014 · Vol. 5, No. 19 · pp. 9150-9168

Keywords: Crizotinib, Pancreatic cancer, c-MET, ALK, Apoptosis

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Xin Chen, Xianping Shi, Chong Zhao, Xiaofen Li, Xiaoying Lan, Shouting Liu, Hongbiao Huang, Ningning Liu, Siyan Liao, Dan Zang, Wenbin Song, Quentin Liu, Bing Z. Carter, Ping Q. Dou, Xuejun Wang, Jinbao Liu

Published Aug 22, 2014 · Vol. 5, No. 19 · pp. 9118-9132

Keywords: Auranofin, proteasome, chronic myelogenous leukemia, imatinib resistance, Bcr-Abl

Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment Priority Research Paper

John T. Isaacs, Susan L. Dalrymple, Marc D. Rosen, Hans Hammers, Anders Olsson, Tomas Leanderson

Published Aug 21, 2014 · Vol. 5, No. 18 · pp. 8093-8106

A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors Clinical Research Papers

Hatem H. Soliman, Erica Jackson, Tony Neuger, Claire E. Dees, Donald R. Harvey, Hyo Han, Roohi Ismail-Khan, Susan Minton, Nicholas N. Vahanian, Charles Link, Daniel M. Sullivan, Scott Antonia

Published Aug 21, 2014 · Vol. 5, No. 18 · pp. 8136-8146

Keywords: Indoximod, 1-methyl-D-tryptophan, immunomodulator, docetaxel, indoleamine 2, 3 dioxygenase

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Annika M. Bourgonje, Anna C. Navis, Jan T.G. Schepens, Kiek Verrijp, Liesbeth Hovestad, Riet Hilhorst, Sheila Harroch, Pieter Wesseling, William P.J. Leenders, Wiljan J.A.J. Hendriks

Published Aug 19, 2014 · Vol. 5, No. 18 · pp. 8690-8702

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell Research Paper

Mayuko Nishi, Hidenori Akutsu, Ayumi Kudoh, Hirokazu Kimura, Naoki Yamamoto, Akihiro Umezawa, Sam W. Lee, Akihide Ryo

Published Aug 17, 2014 · Vol. 5, No. 18 · pp. 8665-8680

Selective targeting of liver cancer with the endothelial marker CD146 Research Paper

Stefan Thomann, Thomas Longerich, Alexandr V. Bazhin, Walter Mier, Peter Schemmer, Eduard Ryschich

Published Aug 13, 2014 · Vol. 5, No. 18 · pp. 8614-8624

Diacylglycerol kinase Î± promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src Research Paper

Pedro Torres-Ayuso, Manuel Daza-MartÃn, Jorge MartÃn-PÃ©rez, Antonia Ãvila-Flores, Isabel MÃ©rida

Published Aug 12, 2014 · Vol. 5, No. 20 · pp. 9710-9726

Wogonin induces cell cycle arrest and erythroid differentiation inÂ imatinib-resistant K562 cells and primary CML cells Research Paper

Hao Yang, Hui Hui, Qian Wang, Hui Li, Kai Zhao, Yuxin Zhou, Yu Zhu, Xiaotang Wang, Qidong You, Qinglong Guo, Na Lu

Published Aug 10, 2014 · Vol. 5, No. 18 · pp. 8188-8201

Efficient lytic induction of kaposiâ€™s sarcoma-associated herpesvirus (KSHV) by the anthracyclines Research Paper

Hyunju Kang, Jaehyung Song, Kwangman Choi, Hyeongki Kim, Miri Choi, So-Young Lee, Chonsaeng Kim, Sang Jun Lee, Moon Jung Song, Hyojeung Kang, Sung Hoon Back, Sang-Bae Han, Sungchan Cho

Published Aug 10, 2014 · Vol. 5, No. 18 · pp. 8515-8527

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Cecilia Evangelisti, Camilla Evangelisti, Gabriella Teti, Francesca Chiarini, Mirella Falconi, Fraia Melchionda, Andrea Pession, Alice Bertaina, Franco Locatelli, James A. McCubrey, Dong Jae Beak, Robert Bittman, Susan Pyne, Nigel J. Pyne, Alberto M. Martelli

Published Aug 6, 2014 · Vol. 5, No. 17 · pp. 7886-7901

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma Research Paper

Francois Lamoureux, Marc Baudâ€™huin, Benjamin Ory, Romain Guiho, Amina Zoubeidi, Martin Gleave, Dominique Heymann, FranÃ§oise RÃ©dini

Published Aug 4, 2014 · Vol. 5, No. 17 · pp. 7805-7819

Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy Research Paper

Jaganmohan R. Jangamreddy, Soumya Panigrahi, Kourosh Lotfi, Manisha Yadav, Subbareddy Maddika, Anil Kumar Tripathi, Sabyasachi Sanyal, Marek J. Åos

Published Aug 4, 2014 · Vol. 5, No. 16 · pp. 7198-7211

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner Research Paper

Akiko Morimoto, Satoshi Serada, Takayuki Enomoto, Ayako Kim, Shinya Matsuzaki, Tsuyoshi Takahashi, Yutaka Ueda, Kiyoshi Yoshino, Masami Fujita, Minoru Fujimoto, Tadashi Kimura, Tetsuji Naka

Published Aug 4, 2014 · Vol. 5, No. 17 · pp. 7776-7787

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

Frankie Lam, Abdullahi Y. Abbas, Hao Shao, Theodosia Teo, Julian Adams, Peng Li, Tracey D. Bradshaw, Peter M. Fischer, Elisabeth Walsby, Chris Pepper, Yi Chen, Jian Ding, Shudong Wang

Published Jul 31, 2014 · Vol. 5, No. 17 · pp. 7691-7704

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism Research Paper

Ahmed Waraky, Karen Akopyan, Vendela Parrow, Thomas StrÃ¶mberg, Magnus Axelson, Lars AbrahmsÃ©n, Arne Lindqvist, Olle Larsson, Eiman Aleem

Published Jul 31, 2014 · Vol. 5, No. 18 · pp. 8379-8392

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells Research Paper

Masashi Idogawa, Tomoko Ohashi, Jun Sugisaka, Yasushi Sasaki, Hiromu Suzuki, Takashi Tokino

Published Jul 27, 2014 · Vol. 5, No. 17 · pp. 7540-7548

Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells Research Paper

Xue-Tao Li, Rui-Jun Ju, Xiu-Ying Li, Fan Zeng, Ji-Feng Shi, Lei Liu, Cheng-Xiang Zhang, Meng-Ge Sun, Jin-Ning Lou, Wan-Liang Lu

Published Jul 26, 2014 · Vol. 5, No. 15 · pp. 6497-6511

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Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer Research Paper

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment Priority Research Paper

A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors Clinical Research Papers

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell Research Paper

Selective targeting of liver cancer with the endothelial marker CD146 Research Paper

Diacylglycerol kinase Î± promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src Research Paper

Wogonin induces cell cycle arrest and erythroid differentiation inÂ imatinib-resistant K562 cells and primary CML cells Research Paper

Efficient lytic induction of kaposiâ€™s sarcoma-associated herpesvirus (KSHV) by the anthracyclines Research Paper

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma Research Paper

Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy Research Paper

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner Research Paper

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism Research Paper

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells Research Paper

Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer Research Paper

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment Priority Research Paper

A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors Clinical Research Papers

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell Research Paper

Selective targeting of liver cancer with the endothelial marker CD146 Research Paper

Diacylglycerol kinase Î± promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src Research Paper

Wogonin induces cell cycle arrest and erythroid differentiation inÂ imatinib-resistant K562 cells and primary CML cells Research Paper

Efficient lytic induction of kaposiâ€™s sarcoma-associated herpesvirus (KSHV) by the anthracyclines Research Paper

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma Research Paper

Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy Research Paper

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner Research Paper

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism Research Paper

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells Research Paper

Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells Research Paper