The Oncosearch | Oncotarget

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

Michal Podrazil, Rudolf Horvath, Etienne Becht, Daniela Rozkova, Pavla Bilkova, Hana Hromadkova, Jana Kayserova, Katerina Vavrova, Jan Lastovicka, Petra Vrabcova, Katerina Kubackova, Zdenka Gasova, Ladislav Jarolim, Marek Babjuk, Radek Spisek, Jirina Bartunkova, Jitka Fucikova

Published May 29, 2015 · Vol. 6, No. 20 · pp. 18192-18205

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Mounia Guerram, Zhen-Zhou Jiang, Bashir Alsiddig Yousef, Aida Mejda Hamdi, Hozeifa Mohamed Hassan, Zi-Qiao Yuan, Hou-Wei Luo, Xiong Zhu, Lu-Yong Zhang

Published May 28, 2015 · Vol. 6, No. 26 · pp. 21865-21877

Lymphatic dysfunction attenuates tumor immunity through impaired antigen presentation Research Paper

Takayuki Kimura, Makoto Sugaya, Tomonori Oka, Andrew Blauvelt, Hitoshi Okochi, Shinichi Sato

Published May 27, 2015 · Vol. 6, No. 20 · pp. 18081-18093

Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis Research Paper

Maciej Nowacki, Marek Wisniewski, Karolina Werengowska-Ciecwierz, Katarzyna Roszek, Joanna Czarnecka, I. Åakomska, Tomasz Kloskowski, Dominik Tyloch, Robert Debski, Katarzyna Pietkun, Marta Pokrywczynska, Dariusz Grzanka, RafaÅ‚ Czajkowski, Gerard Drewa, A. JundziÅ‚Å‚, Joseph K. Agyin, Samy L. Habib, Artur P. Terzyk, Tomasz Drewa

Published May 27, 2015 · Vol. 6, No. 26 · pp. 22776-22798

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Rute Loureiro, Silvia MagalhÃ£es-Novais, Katia A. Mesquita, Ines Baldeiras, Isabel S. Sousa, Ludgero C. Tavares, Ines A. Barbosa, Paulo J. Oliveira, Ignacio Vega-Naredo

Published May 20, 2015 · Vol. 6, No. 19 · pp. 17081-17096

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization Research Paper

Sergey A. Dyshlovoy, Jessica Hauschild, Kerstin Amann, Ksenia M. Tabakmakher, Simone Venz, Reinhard Walther, Alla G. Guzii, Tatiana N. Makarieva, Larisa K. Shubina, Sergey N. Fedorov, Valentin A. Stonik, Carsten Bokemeyer, Stefan Balabanov, Friedemann Honecker, Gunhild v. Amsberg

Published May 19, 2015 · Vol. 6, No. 19 · pp. 17328-17341

The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells Research Paper

Carolina Simioni, Alice Cani, Alberto M. Martelli, Giorgio Zauli, Ayman A.M. Alameen, Simona Ultimo, Giovanna Tabellini, James A. McCubrey, Silvano Capitani, Luca M. Neri

Published May 14, 2015 · Vol. 6, No. 19 · pp. 17147-17160

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Marijke C.C. Sachweh, William C. Stafford, Catherine J. Drummond, Anna R. McCarthy, Maureen Higgins, Johanna Campbell, Bertha Brodin, Elias S.J. ArnÃ©r, Sonia LaÃn

Published May 12, 2015 · Vol. 6, No. 18 · pp. 16488-16506

Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors Research Paper

Meriam Ayadi, AnaÃ¯s Bouygues, Djamila Ouaret, Nathalie Ferrand, Salem Chouaib, Jean-Paul Thiery, Christian Muchardt, MichÃ¨le Sabbah, Annette K. Larsen

Published May 11, 2015 · Vol. 6, No. 21 · pp. 18518-18533

Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patientsâ€™ cells Research Paper

Elena Ciaglia, Giovanni Torelli, Simona Pisanti, Paola Picardi, Alba Dâ€™Alessandro, Chiara Laezza, Anna Maria Malfitano, Donatella Fiore, Antonio Christian Pagano Zottola, Maria Chiara Proto, Giuseppe Catapano, Patrizia Gazzerro, Maurizio Bifulco

Published May 11, 2015 · Vol. 6, No. 17 · pp. 15464-15481

mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib Research Paper

Elyse K. Hanly, Robert B. Bednarczyk, Neha Y. Tuli, Augustine L. Moscatello, H. Dorota Halicka, Jiangwei Li, Jan Geliebter, Zbigniew Darzynkiewicz, Raj K. Tiwari

Published May 9, 2015 · Vol. 6, No. 37 · pp. 39702-39713

Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells Research Paper

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Juri Sakuta, Kazuma Ohyashiki

Published May 8, 2015 · Vol. 6, No. 24 · pp. 20231-20240

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

Ying Shen, Jie Li, Masayuki Nitta, Diahnn Futalan, Tyler Steed, Jeffrey M. Treiber, Zack Taich, Deanna Stevens, Jill Wykosky, Hong-Zhuan Chen, Bob S. Carter, Oren J. Becher, Richard Kennedy, Fumiko Esashi, Jann N. Sarkaria, Frank B. Furnari, Webster K. Cavenee, Arshad Desai, Clark C. Chen

Published May 5, 2015 · Vol. 6, No. 14 · pp. 11751-11767

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents Research Paper

Chenchu Lin, Hanlin Zeng, Junyan Lu, Zuoquan Xie, Wenyi Sun, Cheng Luo, Jian Ding, Shengtao Yuan, Meiyu Geng, Min Huang

Published May 4, 2015 · Vol. 6, No. 24 · pp. 20578-20591

EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy Research Paper

Yun-Tian Li, Xiao-Jun Qian, Yan Yu, Zhen-Hua Li, Rui-Yan Wu, Jiao Ji, Lin Jiao, Xuan Li, Peng-Fei Kong, Wen-Dan Chen, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu

Published Apr 29, 2015 · Vol. 6, No. 19 · pp. 17491-17500

Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation Research Paper

Xuejing Wang, Mingming Ma, Junfang Teng, Jiewen Zhang, Shuang Zhou, Ying Zhang, Erxi Wu, Xuebing Ding

Published Apr 20, 2015 · Vol. 6, No. 15 · pp. 13278-13294

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer Research Paper

Julie Jacobs, Karen Zwaenepoel, Christian Rolfo, Jolien Van den Bossche, Christophe Deben, Karen Silence, Christophe Hermans, Evelien Smits, Paul Van Schil, Filip Lardon, Vanessa Deschoolmeester, Patrick Pauwels

Published Apr 19, 2015 · Vol. 6, No. 15 · pp. 13462-13475

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

Germano Mariano, Maria Rosaria Ricciardi, Daniela Trisciuoglio, Michele Zampieri, Fabio Ciccarone, Tiziana Guastafierro, Roberta Calabrese, Elisabetta Valentini, Agostino Tafuri, Donatella Del Bufalo, Paola Caiafa, Anna Reale

Published Apr 13, 2015 · Vol. 6, No. 17 · pp. 15008-15021

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy Research Paper

FranÃ§ois Bertucci, Pascal Finetti, CÃ©cile Colpaert, Emilie Mamessier, Maxime Parizel, Luc Dirix, Patrice Viens, Daniel Birnbaum, Steven Van Laere

Published Apr 11, 2015 · Vol. 6, No. 15 · pp. 13506-13519

Biological and clinical effects of abiraterone on anti-resorptive and anabolic activity in bone microenvironment Research Paper

Michele Iuliani, Francesco Pantano, Consuelo Buttigliero, Marco Fioramonti, Valentina Bertaglia, Bruno Vincenzi, Alice Zoccoli, Giulia Ribelli, Marcello Tucci, Francesca Vignani, Alfredo Berruti, Giorgio Vittorio Scagliotti, Giuseppe Tonini, Daniele Santini

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 12520-12528

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Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Lymphatic dysfunction attenuates tumor immunity through impaired antigen presentation Research Paper

Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization Research Paper

The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells Research Paper

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors Research Paper

Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patientsâ€™ cells Research Paper

mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib Research Paper

Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents Research Paper

EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy Research Paper

Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation Research Paper

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer Research Paper

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy Research Paper

Biological and clinical effects of abiraterone on anti-resorptive and anabolic activity in bone microenvironment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Lymphatic dysfunction attenuates tumor immunity through impaired antigen presentation Research Paper

Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy: a multidisciplinary study of peritoneal carcinomatosis Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization Research Paper

The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells Research Paper

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells Research Paper

Chronic chemotherapeutic stress promotes evolution of stemness and WNT/beta-catenin signaling in colorectal cancer cells: implications for clinical use of WNT-signaling inhibitors Research Paper

Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patientsâ€™ cells Research Paper

mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib Research Paper

Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells Research Paper

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition Priority Research Paper

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents Research Paper

EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy Research Paper

Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation Research Paper

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer Research Paper

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy Research Paper

Biological and clinical effects of abiraterone on anti-resorptive and anabolic activity in bone microenvironment Research Paper