The Oncosearch | Oncotarget

Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden Research Paper

Erik W. Martin, Marguerite S. Buzza, Kathryn H. Driesbaugh, Shihui Liu, Yolanda M. Fortenberry, Stephen H. Leppla, Toni M. Antalis

Published Sep 15, 2015 · Vol. 6, No. 32 · pp. 33534-33553

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2_a,b^{â€“/â€“} mice favoring autoimmune cholangitis Research Paper

Axel R. Concepcion, January T. Salas, Elena SÃ¡ez, Sarai Sarvide, Alex Ferrer, Ainhoa Portu, Iker Uriarte, Sandra HervÃ¡s-Stubbs, Ronald P.J. Oude Elferink, JesÃºs Prieto, Juan F. Medina

Published Sep 15, 2015 · Vol. 6, No. 30 · pp. 28588-28606

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

Xuejie Jiang, Zhixiang Wang, Bingjie Ding, Changxin Yin, Qingxiu Zhong, Bing Z. Carter, Guopan Yu, Ling Jiang, Jieyu Ye, Min Dai, Yu Zhang, Shuang Liang, Qingxia Zhao, Qifa Liu, Fanyi Meng

Published Sep 10, 2015 · Vol. 6, No. 32 · pp. 33612-33622

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

Heng Zhou, Sabrina Forveille, Allan Sauvat, Valentina Sica, Valentina Izzo, SylvÃ¨re Durand, Kevin MÃ¼ller, Peng Liu, Laurence Zitvogel, Ã˜ystein Rekdal, Oliver Kepp, Guido Kroemer

Published Sep 10, 2015 · Vol. 6, No. 29 · pp. 26599-26614

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells Research Paper

Joanna Kopecka, Stefania Porto, Sara Lusa, Elena Gazzano, Giuseppina Salzano, Antonio Giordano, Vincenzo Desiderio, Dario Ghigo, Michele Caraglia, Giuseppe De Rosa, Chiara Riganti

Published Sep 9, 2015 · Vol. 6, No. 31 · pp. 31461-31478

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

FÃ©lix Gremonprez, Benedicte Descamps, Andrei Izmer, Christian Vanhove, Frank Vanhaecke, Olivier De Wever, Wim Ceelen

Published Sep 7, 2015 · Vol. 6, No. 30 · pp. 29889-29900

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells Research Paper

Grazia Ambrosini, Ashley D. Sawle, Elgilda Musi, Gary K. Schwartz

Published Sep 5, 2015 · Vol. 6, No. 32 · pp. 33397-33409

Regulation of Bim in Health and Disease Priority Reviews

Ronit Vogt Sionov, Spiros A. Vlahopoulos, Zvi Granot

Published Sep 5, 2015 · Vol. 6, No. 27 · pp. 23058-23134

PRMT6 increases cytoplasmic localization of p21^CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents Research Paper

Makoto Nakakido, Zhenzhong Deng, Takehiro Suzuki, Naoshi Dohmae, Yusuke Nakamura, Ryuji Hamamoto

Published Sep 3, 2015 · Vol. 6, No. 31 · pp. 30957-30967

Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy Clinical Research Papers

Anna K. Brady, Jonathan D. McNeill, Brendan Judy, Joshua Bauml, Tracey L. Evans, Roger B. Cohen, Corey Langer, Anil Vachani, Charu Aggarwal

Published Sep 3, 2015 · Vol. 6, No. 30 · pp. 30287-30294

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Giuseppe Palma, Giuseppe Frasci, Andrea Chirico, Emanuela Esposito, Claudio Siani, Carmela Saturnino, Claudio Arra, Gennaro Ciliberto, Antonio Giordano, Massimiliano Dâ€™Aiuto

Published Aug 30, 2015 · Vol. 6, No. 29 · pp. 26560-26574

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling Review

Young Kwang Chae, Su Yun Chung, Andrew A Davis, Benedito A Carneiro, Sunandana Chandra, Jason Kaplan, Aparna Kaylan, Francis J Giles

Published Aug 21, 2015 · Vol. 6, No. 35 · pp. 37117-37134

Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression Research Paper

Marisa Granato, Maria Saveria Gilardini Montani, Maria Rosaria Filardi, Alberto Faggioni, Mara Cirone

Published Aug 18, 2015 · Vol. 6, No. 30 · pp. 29543-29554

Human mesenchymal stem cells enhance the systemic effects of radiotherapy Research Paper

VirgÃnea de AraÃºjo Farias, Francisco Oâ€™Valle, Borja Alonso Lerma, Carmen Ruiz de AlmodÃ³var, JesÃºs J. LÃ³pez-PeÃ±alver, Ana Nieto, Ana Santos, Beatriz Irene FernÃ¡ndez, Ana Guerra-Librero, MarÃa Carmen Ruiz-Ruiz, DamiÃ¡n Guirado, Thomas Schmidt, Francisco Javier Oliver, JosÃ© Mariano Ruiz de AlmodÃ³var

Published Aug 17, 2015 · Vol. 6, No. 31 · pp. 31164-31180

Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site Research Paper

Maxime Thoreau, HweiXian Leong Penny, KarWai Tan, Fabienne Regnier, Julia Miriam Weiss, Bernett Lee, Ludger Johannes, Estelle Dransart, AgnÃ¨s Le Bon, Jean-Pierre Abastado, Eric Tartour, Alain Trautmann, NadÃ¨ge Bercovici

Published Aug 11, 2015 · Vol. 6, No. 29 · pp. 27832-27846

Dequalinium blocks macrophage-induced metastasis following local radiation Research Paper

Michael Timaner, Rotem Bril, Orit Kaidar-Person, Chen Rachman-Tzemah, Dror Alishekevitz, Ruslana Kotsofruk, Valeria Miller, Alexander Nevelsky, Shahar Daniel, Ziv Raviv, Susan A. Rotenberg, Yuval Shaked

Published Aug 6, 2015 · Vol. 6, No. 29 · pp. 27537-27554

Rituximab-induced HMGB1 release is associated with inhibition of STAT3 activity in human diffuse large B-cell lymphoma Research Paper

Tiansuo Zhao, He Ren, Xiuchao Wang, Pengfei Liu, Fan Yan, Wenna Jiang, Yang Li, Jing Li, John G Gribben, Li Jia, Jihui Hao

Published Jul 31, 2015 · Vol. 6, No. 29 · pp. 27816-27831

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

Shanzhou Duan, Ying Tsai, Peter Keng, Yongbing Chen, Soo Ok Lee, Yuhchyau Chen

Published Jul 30, 2015 · Vol. 6, No. 29 · pp. 27651-27660

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

Xiao Zhi, Wei Chen, Fei Xue, Chao Liang, Bryan Wei Chen, Yue Zhou, Liang Wen, Liqiang Hu, Jian Shen, Xueli Bai, Tingbo Liang

Published Jul 21, 2015 · Vol. 6, No. 28 · pp. 26230-26241

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

Jian Xu, Xiu-Jun Liu, Liang Li, Sheng-Hua Zhang, Yi Li, Rui-Juan Gao, Yong-Su Zhen

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 26322-26334

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Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden Research Paper

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2_a,b^{â€“/â€“} mice favoring autoimmune cholangitis Research Paper

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells Research Paper

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells Research Paper

Regulation of Bim in Health and Disease Priority Reviews

PRMT6 increases cytoplasmic localization of p21^CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents Research Paper

Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy Clinical Research Papers

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling Review

Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression Research Paper

Human mesenchymal stem cells enhance the systemic effects of radiotherapy Research Paper

Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site Research Paper

Dequalinium blocks macrophage-induced metastasis following local radiation Research Paper

Rituximab-induced HMGB1 release is associated with inhibition of STAT3 activity in human diffuse large B-cell lymphoma Research Paper

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden Research Paper

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,bâ€“/â€“ mice favoring autoimmune cholangitis Research Paper

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells Research Paper

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells Research Paper

Regulation of Bim in Health and Disease Priority Reviews

PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents Research Paper

Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy Clinical Research Papers

Triple negative breast cancer: looking for the missing link between biology and treatments Research Perspective

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling Review

Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression Research Paper

Human mesenchymal stem cells enhance the systemic effects of radiotherapy Research Paper

Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site Research Paper

Dequalinium blocks macrophage-induced metastasis following local radiation Research Paper

Rituximab-induced HMGB1 release is associated with inhibition of STAT3 activity in human diffuse large B-cell lymphoma Research Paper

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy Research Paper

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2_a,b^{â€“/â€“} mice favoring autoimmune cholangitis Research Paper

PRMT6 increases cytoplasmic localization of p21^CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents Research Paper