The Oncosearch | Oncotarget

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette, Ugra S. Singh

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11709-11722

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma Research Paper

Iza Denis, Laurent Cellerin, Marc Gregoire, Christophe Blanquart

Published Oct 18, 2014 · Vol. 5, No. 22 · pp. 11641-11652

Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma Research Paper

Binghao Li, Xiaobing Zhu, Lingling Sun, Li Yuan, Jian Zhang, Hengyuan Li, Zhaoming Ye

Published Oct 4, 2014 · Vol. 5, No. 21 · pp. 10791-10802

Keywords: Osteosarcoma, Adoptive immunotherapy, Cancer/testis antigens, Demethylating treatment, Combination therapy

The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells Research Paper

Lymor Ringer, Paul Sirajuddin, Lucas Tricoli, Sarah Waye, Muhammad Umer Choudhry, Erika Parasido, Angiela Sivakumar, Mary Heckler, Aisha Naeem, Iman Abdelgawad, Xuefeng Liu, Adam S. Feldman, Richard J. Lee, Chin-Lee Wu, Venkata Yenugonda, Bhaskar Kallakury, Anatoly Dritschilo, John Lynch, Richard Schlegel, Olga Rodriguez, Richard G. Pestell, Maria Laura Avantaggiati, Chris Albanese

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10678-10691

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-Î² and the ectodomain of the TGF-Î² receptor II potentiates antitumor immunity Research Paper

Kevin Van der Jeught, Patrick Tjok Joe, Lukasz Bialkowski, Carlo Heirman, Lidia Daszkiewicz, Therese Liechtenstein, David Escors, Kris Thielemans, Karine Breckpot

Published Sep 19, 2014 · Vol. 5, No. 20 · pp. 10100-10113

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation Research Paper

Carolina Simioni, Alice Cani, Alberto M. Martelli, Giorgio Zauli, Giovanna Tabellini, James McCubrey, Silvano Capitani, Luca M. Neri

Published Sep 16, 2014 · Vol. 5, No. 20 · pp. 10034-10047

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Glen P. Marszalowicz, Adam E. Snook, Michael S. Magee, Dante Merlino, Lisa D. Berman-Booty, Scott A. Waldman

Published Sep 8, 2014 · Vol. 5, No. 19 · pp. 9460-9471

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

Jun-Bum Park, Sameer Agnihotri, Brian Golbourn, Kelsey C. Bertrand, Amanda Luck, Nesrin Sabha, Christian A. Smith, Sara Byron, Gelareh Zadeh, Sidney Croul, Michael Berens, James T. Rutka

Published Sep 5, 2014 · Vol. 5, No. 19 · pp. 9382-9395

The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer Research Paper

Martin C. Sadowski, Rebecca H. Pouwer, Jennifer H. Gunter, Amy A. Lubik, Ronald J. Quinn, Colleen C. Nelson

Published Sep 3, 2014 · Vol. 5, No. 19 · pp. 9362-9381

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Richard E. Kast, Georg Karpel-Massler, Marc-Eric Halatsch

Published Aug 29, 2014 · Vol. 5, No. 18 · pp. 8052-8082

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Shachar Raz, Michal Stark, Yehuda G. Assaraf

Published Aug 27, 2014 · Vol. 5, No. 19 · pp. 9183-9198

Treatment of osteosarcoma with microwave thermal ablation to induce immunogenic cell death Research Paper

Zhe Yu, Jie Geng, Minghua Zhang, Yong Zhou, Qingyu Fan, Jingyuan Chen

Published Aug 4, 2014 · Vol. 5, No. 15 · pp. 6526-6539

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice Research Paper

Therese Liechtenstein, Noemi Perez-Janices, Maria Gato, Fabio Caliendo, Grazyna Kochan, Idoia Blanco-Luquin, Frederick Arce, David Guerrero-Setas, Joaquin Fernandez-Irigoyen, Enrique Santamaria, Karine Breckpot, David Escors

Published Aug 4, 2014 · Vol. 5, No. 17 · pp. 7843-7857

Efficacy of dual PI-3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia Research Paper

Jacky Wong, Robert Welschinger, John Hewson, Kenneth . F Bradstock, Linda J. Bendall

Published Jul 25, 2014 · Vol. 5, No. 21 · pp. 10460-10472

In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy Research Paper

Rogerio B. Craveiro, Michael Ehrhardt, Martin I. Holst, Thorsten Pietsch, Dagmar Dilloo

Published Jul 22, 2014 · Vol. 5, No. 16 · pp. 7149-7161

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

VÃctor M. Blanco, Zhengtao Chu, Subrahmanya D. Vallabhapurapu, Mahaboob K. Sulaiman, Ady Kendler, Olivier Rixe, Ronald E. Warnick, Robert S. Franco, Xiaoyang Qi

Published Jul 14, 2014 · Vol. 5, No. 16 · pp. 7105-7118

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid Research Paper

Manuela Porru, Silvia Zappavigna, Giuseppina Salzano, Amalia Luce, Antonella Stoppacciaro, Maria Luisa Balestrieri, Simona Artuso, Sara Lusa, Giuseppe De Rosa, Carlo Leonetti, Michele Caraglia

Published Jul 9, 2014 · Vol. 5, No. 21 · pp. 10446-10459

Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter Research Paper

Ho Kyung Seo, Jeong Bin Seo, Jae-Kook Nam, Kyung-Chae Jeong, Seung-Pil Shin Shin, In-Hoo Kim, Sang Don Lee, Sang-Jin Lee

Published Jun 30, 2014 · Vol. 5, No. 14 · pp. 5615-5623

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Petra Popovics, Andrew V. Schally, Luca Szalontay, Norman L. Block, Ferenc G. Rick

Published Jun 29, 2014 · Vol. 5, No. 12 · pp. 4567-4578

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB Research Paper

Yulia N. Demchenko, Leslie A. Brents, Zhihong Li, Leif P. Bergsagel, Lawrence R. McGee, Michael W. Kuehl

Published Jun 23, 2014 · Vol. 5, No. 12 · pp. 4554-4566

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Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma Research Paper

Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma Research Paper

The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells Research Paper

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-Î² and the ectodomain of the TGF-Î² receptor II potentiates antitumor immunity Research Paper

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation Research Paper

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer Research Paper

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Treatment of osteosarcoma with microwave thermal ablation to induce immunogenic cell death Research Paper

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice Research Paper

Efficacy of dual PI-3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia Research Paper

In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy Research Paper

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid Research Paper

Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter Research Paper

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma Research Paper

Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma Research Paper

The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells Research Paper

Intratumoral administration of mRNA encoding a fusokine consisting of IFN-Î² and the ectodomain of the TGF-Î² receptor II potentiates antitumor immunity Research Paper

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation Research Paper

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer Research Paper

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia Research Paper

Treatment of osteosarcoma with microwave thermal ablation to induce immunogenic cell death Research Paper

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice Research Paper

Efficacy of dual PI-3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia Research Paper

In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy Research Paper

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors Research Paper

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid Research Paper

Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter Research Paper

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB Research Paper