The Oncosearch | Oncotarget

TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma Research Paper

Mariano Francesco Caratozzolo, Alessio Valletti, Margherita Gigante, Italia Aiello, Francesca Mastropasqua, Flaviana Marzano, Pasquale Ditonno, Giuseppe Carrieri, HÃ©lÃ¨ne Simonnet, Anna Maria Dâ€™Erchia, Elena Ranieri, Graziano Pesole, Elisabetta SbisÃ, Apollonia Tullo

Published Jun 8, 2014 · Vol. 5, No. 17 · pp. 7446-7457

Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo Research Paper

Siao-Syun Guan, Jungshan Chang, Chun-Chia Cheng, Tsai-Yueh Luo, Ai-Sheng Ho, Chia-Chi Wang, Cheng-Tien Wu, Shing-Hwa Liu

Published Jun 1, 2014 · Vol. 5, No. 13 · pp. 4868-4880

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Annalisa Pezzolo, Danilo Marimpietri, Lizzia Raffaghello, Claudia Cocco, Angela Pistorio, Claudio Gambini, Michele Cilli, Alberto Horenstein, Fabio Malavasi, Vito Pistoia

Published May 26, 2014 · Vol. 5, No. 21 · pp. 10368-10381

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 Research Paper

Chiara Agnoletto, Elisabetta Melloni, Fabio Casciano, Gian Matteo Rigolin, Erika Rimondi, Claudio Celeghini, Laura Brunelli, Antonio Cuneo, Paola Secchiero, Giorgio Zauli

Published May 26, 2014 · Vol. 5, No. 12 · pp. 4347-4360

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib Research Paper

Alberto RamÃrez, Houria Boulaiz, Cynthia Morata-Tarifa, Macarena PerÃ¡n, Gema JimÃ©nez, Manuel Picon-Ruiz, Ahmad Agil, Olga Cruz-LÃ³pez, Ana Conejo-GarcÃa, JoaquÃn M. Campos, Ana SÃ¡nchez, MarÃa A. GarcÃa, Juan A. Marchal

Published May 13, 2014 · Vol. 5, No. 11 · pp. 3590-3606

An updated overview of HPV-associated head and neck carcinomas Review

Apostolos Zaravinos

Published May 1, 2014 · Vol. 5, No. 12 · pp. 3956-3969

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

Yair Tal, Shlomo Yaakobi, Miryam Horovitz-Fried, Einav Safyon, Benyamin Rosental, Angel Porgador, Cyrille J. Cohen

Published Apr 24, 2014 · Vol. 5, No. 21 · pp. 10949-10958

Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability Research Paper

Guangxun Gao, Liang Chen, Jingxia Li, Dongyun Zhang, Yong Fang, Haishan Huang, Xiequn Chen, Chuanshu Huang

Published Mar 26, 2014 · Vol. 5, No. 9 · pp. 2664-2677

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

Maxim A. Shevtsov, Elena Y. Komarova, Darya A. Meshalkina, Natalia V. Bychkova, Nikolai D. Aksenov, Sergey V. Abkin, Boris A. Margulis, Irina V. Guzhova

Published Mar 22, 2014 · Vol. 5, No. 10 · pp. 3101-3114

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

Yanira Gonzalez, Baikuntha Aryal, Leena Chehab, V Ashutosh Rao

Published Mar 12, 2014 · Vol. 5, No. 6 · pp. 1526-1537

Keywords: autophagy, reactive oxygen species, mitoquinone, breast cancer

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts Priority Research Paper

Xiaoqi Xie, Nitu Bansal, Tazeem Shaik, John E. Kerrigan, Tamara Minko, Olga Garbuzenko, Emine Ercikan Abali, Nadine Johnson-Farley, Debabrata Banerjee, Kathleen W. Scotto, Joseph R. Bertino

Published Mar 11, 2014 · Vol. 5, No. 4 · pp. 901-907

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Arnau Montraveta, Silvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Laia Rosich, Patricia PÃ©rez-GalÃ¡n, Itziar Salaverria, Silvia BeÃ, Susana G. Kalko, MercÃ¨ de Frias, Clara CampÃ s, GaÃ«l RouÃ©, Dolors Colomer

Published Jan 25, 2014 · Vol. 5, No. 3 · pp. 726-739

Keywords: Acadesine, rituximab, mantle cell lymphoma, xenograft mouse model

Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition Research Paper

Chueh-Chuan Yen, Chung-Der Hsiao, Wei-Ming Chen, Yao-Shan Wen, Yung-Chan Lin, Ting-Wei Chang, Fang-Yi Yao, Shih-Chieh Hung, Jir-You Wang, Jen-Hwey Chiu, Hsei-Wei Wang, Chi-Hung Lin, Tain-Hsiung Chen, Paul Chih-Hsueh Chen, Chien-Lin Liu, Cheng-Hwai Tzeng, Jonathan A. Fletcher

Published Jan 21, 2014 · Vol. 5, No. 3 · pp. 716-725

Keywords: 15d-PGJ2, AKT, PLK1, osteosarcoma

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

Richard Knight, Mikhail Gostev, Sergei Ilisavskii, Anne E Willis, Gerry Melino, Alexey V Antonov

Published Jan 21, 2014 · Vol. 5, No. 3 · pp. 659-666

Keywords: oncotargets, drug action mechanisms, polypharmacology

Immunogenicity of targeted lentivectors Research Paper

Cleo Goyvaerts, De Groeve Kurt, Sandra Van Lint, Carlo Heirman, Jo A. Van Ginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans, Karine Breckpot

Published Jan 19, 2014 · Vol. 5, No. 3 · pp. 704-715

Keywords: antitumor immunotherapy, lentiviral vectors, targeting, antigen-presenting cells

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

John T. Heap, Jan Theys, Muhammad Ehsaan, Aleksandra M Kubiak, Ludwig Dubois, Kim Paesmans, Lieve Van Mellaert, Richard Knox, Sarah A. Kuehne, Phillipe Lambin, Nigel P. Minton

Published Jan 12, 2014 · Vol. 5, No. 7 · pp. 1761-1769

AKT mediates actinomycin D-induced p53 expression Research Paper

Chih-Shou Chen, Dong-Ru Ho, Fei-Yun Chen, Chang-Rong Chen, Yu-De Ke, Jyan-Gwo J Su

Published Jan 11, 2014 · Vol. 5, No. 3 · pp. 693-703

Keywords: Actinomycin D, AKT, p53

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

Elisabeth Walsby, Guy Pratt, Hao Shao, Abdullah Y. Abbas, Peter M. Fischer, Tracey D. Bradshaw, Paul Brennan, Chris Fegan, Shudong Wang, Chris Pepper

Published Dec 18, 2013 · Vol. 5, No. 2 · pp. 375-385

Keywords: CLL, cdk9, synergy, MCL1

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Chiou-Tsun Tsai, Pei-Ming Yang, Ting-Rong Chern, Shu-Hui Chuang, Jung-Hsin Lin, Lars Klemm, Markus MÃ¼schen, Ching-Chow Chen

Published Nov 25, 2013 · Vol. 5, No. 1 · pp. 211-223

Keywords: AID, 5-aza-CdR, Zebularine, DNMT1

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper

Veronica Martinez-Marignac, Nader Toban, Miguel Bazile, Raquel Aloyz

Published Nov 7, 2013 · Vol. 4, No. 12 · pp. 2550-2566

Keywords: CLL, AMPK, Dasatinib, kinase inhibitor, metabolism, glycolysis, OXPHOS

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TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma Research Paper

Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo Research Paper

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 Research Paper

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib Research Paper

An updated overview of HPV-associated head and neck carcinomas Review

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability Research Paper

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts Priority Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

Immunogenicity of targeted lentivectors Research Paper

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

AKT mediates actinomycin D-induced p53 expression Research Paper

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma Research Paper

Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo Research Paper

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 Research Paper

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib Research Paper

An updated overview of HPV-associated head and neck carcinomas Review

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA stability Research Paper

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity Research Paper

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts Priority Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition Research Paper

Large scale integration of drug-target information reveals poly-pharmacological drug action mechanisms in tumor cell line growth inhibition assays Research Paper

Immunogenicity of targeted lentivectors Research Paper

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

AKT mediates actinomycin D-induced p53 expression Research Paper

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine Research Paper

Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming Research Paper