The Oncosearch | Oncotarget

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Fiona K. Middleton, Miranda J. Patterson, Claire J. Elstob, Sarah Fordham, Ashleigh Herriott, Mark A. Wade, Aiste McCormick, Richard Edmondson, Felicity E.B. May, James M. Allan, John R. Pollard, Nicola J. Curtin

Published Oct 15, 2015 · Vol. 6, No. 32 · pp. 32396-32409

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells Research Paper

Maria Beatrice Morelli, Consuelo Amantini, Matteo Santoni, Alessandra Soriani, Massimo Nabissi, Claudio Cardinali, Angela Santoni, Giorgio Santoni

Published Oct 14, 2015 · Vol. 6, No. 34 · pp. 36245-36259

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia Research Paper

Jizhong Liu, Ashish Masurekar, Suzanne Johnson, Sohini Chakraborty, John Griffiths, Duncan Smith, Seema Alexander, Clare Dempsey, Catriona Parker, Stephanie Harrison, Yaoyong Li, Crispin Miller, Yujun Di, Zhumur Ghosh, Shekhar Krishnan, Vaskar Saha

Published Oct 13, 2015 · Vol. 6, No. 40 · pp. 43048-43064

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Sandeep S. Negi, Patrick Brown

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34846-34858

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

BegoÃ±a Martin-Castillo, Eugeni Lopez-Bonet, Elisabet CuyÃ s, Gemma ViÃ±as, Sonia Pernas, Joan Dorca, Javier A. Menendez

Published Oct 12, 2015 · Vol. 6, No. 32 · pp. 32317-32338

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

So-Yeon Park, Min-Jin Kim, Sang-A Park, Jung-Shin Kim, Kyung-Nan Min, Dae-Kee Kim, Woosung Lim, Jeong-Seok Nam, Yhun Yhong Sheen

Published Oct 9, 2015 · Vol. 6, No. 35 · pp. 37526-37543

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Diana Spiegelberg, Adrian Dascalu, Anja C. Mortensen, Andris Abramenkovs, Gamze Kuku, Marika Nestor, Bo StenerlÃ¶w

Published Oct 6, 2015 · Vol. 6, No. 34 · pp. 35652-35666

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma Research Paper

Lotte Spel, Jaap-Jan Boelens, Dirk M. van der Steen, Nina J.G. Blokland, Max M. van Noesel, Jan J. Molenaar, Mirjam H.M. Heemskerk, Marianne Boes, Stefan Nierkens

Published Oct 6, 2015 · Vol. 6, No. 34 · pp. 35770-35781

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Chun-Han Chen, Chia-Hwa Lee, Jing-Ping Liou, Che-Ming Teng, Shiow-Lin Pan

Published Oct 5, 2015 · Vol. 6, No. 34 · pp. 35991-36002

Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells Research Paper

Xi Chen, Kaori Sakamoto, Frederick D. Quinn, Huanchun Chen, Zhenfang Fu

Published Sep 30, 2015 · Vol. 6, No. 32 · pp. 32456-32467

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Yizhu Li, Priyanka Saini, Anusha Sriraman, Matthias Dobbelstein

Published Sep 29, 2015 · Vol. 6, No. 32 · pp. 32339-32352

Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis Priority Research Paper

Xiao Feng, Ling Tian, Zhengxiang Zhang, Yang Yu, Jin Cheng, Yanping Gong, Chuan-Yuan Li, Qian Huang

Published Sep 29, 2015 · Vol. 6, No. 32 · pp. 32353-32367

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Da Eun Jeong, Hye Jin Song, Sharon Lim, Se Jeong Lee, Joung Eun Lim, Do-Hyun Nam, Kyeung Min Joo, Byong Chang Jeong, Seong Soo Jeon, Han Yong Choi, Hye Won Lee

Published Sep 28, 2015 · Vol. 6, No. 32 · pp. 33046-33064

Antigen spreading-induced CD8⁺T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells Research Paper

Zhe Yu, Zhiwu Tan, Boon Kiat Lee, Jiansong Tang, Xilin Wu, Ka-Wai Cheung, Nathan Tin Lok Lo, Kwan Man, Li Liu, Zhiwei Chen

Published Sep 28, 2015 · Vol. 6, No. 32 · pp. 32426-32438

A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer Research Paper

Joe R Delaney, Chandni Patel, Katelyn E McCabe, Dan Lu, Mitzie-Ann Davis, Isabelle Tancioni, Tami von Schalscha, Alena Bartakova, Carley Haft, David D Schlaepfer, Dwayne G Stupack

Published Sep 22, 2015 · Vol. 6, No. 31 · pp. 31104-31118

Sorafenib-induced defective autophagy promotes cell death by necroptosis Research Paper

Pedram Kharaziha, Dimitris Chioureas, George Baltatzis, Pedro Fonseca, Patricia Rodriguez, Vladimir Gogvadze, Lena Lennartsson, Ann-Charlotte BjÃ¶rklund, Boris Zhivotovsky, Dan GrandÃ©r, Lars Egevad, Sten Nilsson, Theocharis Panaretakis

Published Sep 22, 2015 · Vol. 6, No. 35 · pp. 37066-37082

Cytotoxic T cell responses are enhanced by antigen design involving the presentation of MUC1 peptide on cholera toxin B subunit Research Paper

Wuguang Lu, Lingchong Qiu, Zhanpeng Yan, Zhibing Lin, Meng Cao, Chunping Hu, Zhigang Wang, Jin Wang, Ye Yu, Xiaoyang Cheng, Peng Cao, Rongxiu Li

Published Sep 21, 2015 · Vol. 6, No. 33 · pp. 34537-34548

Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinoma Research Paper

Yoo-Young Lee, Hye-Kyung Jeon, Ji Eun Hong, Young Jae Cho, Ji Yoon Ryu, Jung-Joo Choi, Sang Hoon Lee, Gun Yoon, Woo Young Kim, In-Gu Do, Min Kyu Kim, Tae-Joong Kim, Chel Hun Choi, Jeong-Won Lee, Duk-Soo Bae, Byoung-Gie Kim

Published Sep 19, 2015 · Vol. 6, No. 33 · pp. 35040-35050

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Stefano Iacovelli, Maria Rosaria Ricciardi, Matteo Allegretti, Simone Mirabilii, Roberto Licchetta, Paola Bergamo, Cinzia Rinaldo, Ann Zeuner, Robin FoÃ, Michele Milella, James A. McCubrey, Alberto M. Martelli, Agostino Tafuri

Published Sep 16, 2015 · Vol. 6, No. 31 · pp. 32089-32103

Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity Research Paper

Manh-Cuong Vo, Hyun-Ju Lee, Jong-Seok Kim, My-Dung Hoang, Nu-Ri Choi, Joon Haeng Rhee, Vinoth-Kumar Lakshmanan, Sung-Jae Shin, Je-Jung Lee

Published Sep 16, 2015 · Vol. 6, No. 32 · pp. 33781-33790

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Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells Research Paper

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia Research Paper

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma Research Paper

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells Research Paper

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis Priority Research Paper

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Antigen spreading-induced CD8⁺T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells Research Paper

A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer Research Paper

Sorafenib-induced defective autophagy promotes cell death by necroptosis Research Paper

Cytotoxic T cell responses are enhanced by antigen design involving the presentation of MUC1 peptide on cholera toxin B subunit Research Paper

Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinoma Research Paper

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition Priority Research Paper

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells Research Paper

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia Research Paper

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas Research Perspective

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma Research Paper

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells Research Paper

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis Priority Research Paper

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Antigen spreading-induced CD8+T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells Research Paper

A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer Research Paper

Sorafenib-induced defective autophagy promotes cell death by necroptosis Research Paper

Cytotoxic T cell responses are enhanced by antigen design involving the presentation of MUC1 peptide on cholera toxin B subunit Research Paper

Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinoma Research Paper

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity Research Paper

Antigen spreading-induced CD8⁺T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells Research Paper