The Oncosearch | Oncotarget

Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells Research Paper

Chengguang Zhao, Hui Xiao, Xiaojuan Wu, Chenglong Li, Guang Liang, Shulin Yang, Jiayuh Lin

Published May 4, 2015 · Vol. 6, No. 16 · pp. 14472-14487

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes Research Paper

Divya Bhagirath, Xiangshan Zhao, William W. West, Fang Qiu, Hamid Band, Vimla Band

Published Apr 22, 2015 · Vol. 6, No. 11 · pp. 9018-9030

Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway Research Paper

Hao Zhang, Yan Ma, Shenghua Zhang, Hong Liu, Hongwei He, Naren Li, Yuyan Gong, Shuangshuang Zhao, Jian-dong Jiang, Rong-guang Shao

Published Apr 20, 2015 · Vol. 6, No. 19 · pp. 17039-17053

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer Research Paper

BalÃ¡zs GyÅ‘rffy, Iwona Stelniec-Klotz, Christian Sigler, Katharina Kasack, Torben Redmer, Yu Qian, Reinhold SchÃ¤fer

Published Apr 19, 2015 · Vol. 6, No. 15 · pp. 13334-13346

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion Research Paper

Wen-Liang Chen, Andrew Barszczyk, Ekaterina Turlova, Marielle Deurloo, Baosong Liu, Burton B. Yang, James T. Rutka, Zhong-Ping Feng, Hong-Shuo Sun

Published Apr 19, 2015 · Vol. 6, No. 18 · pp. 16321-16340

Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-Î²/SMAD signaling Research Paper

Hong-Lin Jiang, He-Fen Sun, Shui-Ping Gao, Liang-Dong Li, Xin Hu, Jiong Wu, Wei Jin

Published Apr 19, 2015 · Vol. 6, No. 18 · pp. 16352-16365

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Xiaoqing Jia, Qi Hong, Li Lei, Daqiang Li, Jianwei Li, Miao Mo, Yujie Wang, Zhimin Shao, Zhenzhou Shen, Jingyi Cheng, Guangyu Liu

Published Apr 13, 2015 · Vol. 6, No. 11 · pp. 8648-8662

RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers Clinical Research Papers

Annemarie Boleij, Bastiaan B.J. Tops, Paul D.M. Rombout, Elizabeth M. Dequeker, Marjolijn J.L. Ligtenberg, J. Han van Krieken, Dutch RAS EQA Initiative

Published Apr 12, 2015 · Vol. 6, No. 17 · pp. 15681-15689

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Joffrey Pelletier, DaniÃ¨le Roux, Benoit Viollet, Nathalie M. Mazure, Jacques PouyssÃ©gur

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 11833-11847

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis Research Paper

Xi Feng, Frank Szulzewsky, Alexan Yerevanian, Zhihong Chen, David Heinzmann, Rikke Darling Rasmussen, Virginia Alvarez-Garcia, Yeonghwan Kim, Bingcheng Wang, Ilaria Tamagno, Hao Zhou, Xiaoxia Li, Helmut Kettenmann, Richard M. Ransohoff, Dolores Hambardzumyan

Published Mar 30, 2015 · Vol. 6, No. 17 · pp. 15077-15094

MTH1 expression is required for effective transformation by oncogenic HRAS Research Paper

Maria G. Giribaldi, Anisleidys Monoz, Katherine Halvorsen, Asmita Patel, Priyamvada Rai

Published Mar 19, 2015 · Vol. 6, No. 13 · pp. 11519-11529

Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway Research Paper

Jui-Chieh Chen, Yu-Ju Chen, Chih-Yang Lin, Yi-Chin Fong, Chin-Jung Hsu, Chun-Hao Tsai, Jen-Liang Su, Chih-Hsin Tang

Published Mar 18, 2015 · Vol. 6, No. 13 · pp. 11434-11446

Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development Research Paper

Rong Deng, Xian Zhao, YingYing Qu, Cheng Chen, Changhong Zhu, Hailong Zhang, Haihua Yuan, Hui Jin, Xin Liu, Yanli Wang, Qin Chen, Jian Huang, Jianxiu Yu

Published Mar 18, 2015 · Vol. 6, No. 11 · pp. 9355-9369

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

Friederike Braig, Manuela MÃ¤rz, Aneta Schieferdecker, Alexander Schulte, Mareike Voigt, Alexander Stein, Tobias Grob, Malik Alawi, Daniela Indenbirken, Malte Kriegs, Erik Engel, Udo Vanhoefer, Adam Grundhoff, Sonja Loges, Kristoffer Riecken, Boris Fehse, Carsten Bokemeyer, Mascha Binder

Published Mar 14, 2015 · Vol. 6, No. 14 · pp. 12035-12047

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

Davide Valente, Gianluca Bossi, Alice Moncada, Mara Tornincasa, Stefania Indelicato, Salvatore Piscuoglio, Eva Diamantis Karamitopoulou, Armando Bartolazzi, Giovanna Maria Pierantoni, Alfredo Fusco, Silvia Soddu, Cinzia Rinaldo

Published Mar 14, 2015 · Vol. 6, No. 12 · pp. 10320-10334

New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma Research Paper

Valerio Costa, Roberta Esposito, Carmela Ziviello, Romina Sepe, Larissa Valdemarin Bim, Nunzio Antonio Cacciola, Myriam Decaussin-Petrucci, Pierlorenzo Pallante, Alfredo Fusco, Alfredo Ciccodicola

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11242-11251

NF2 blocks Snail-mediated p53 suppression in mesothelioma Research Paper

Jung-Hyun Cho, Su-Jin Lee, Ah-Young Oh, Min-Ho Yoon, Tae-Geun Woo, Bum-Joon Park

Published Mar 12, 2015 · Vol. 6, No. 12 · pp. 10073-10085

Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach Research Paper

Peng Wang, Ming Song, Zhao-lei Zeng, Chao-feng Zhu, Wen-hua Lu, Jing Yang, Ming-zhe Ma, A-min Huang, Yumin Hu, Peng Huang

Published Feb 27, 2015 · Vol. 6, No. 6 · pp. 3947-3962

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia Clinical Research Papers

Kati KÃ¤mpjÃ¤rvi, Tiina M. JÃ¤rvinen, Tuomas Heikkinen, Amy S. Ruppert, Leigha Senter, Kevin W. Hoag, Olli Dufva, Mika Kontro, Laura Rassenti, Erin Hertlein, Thomas J. Kipps, Kimmo Porkka, John C. Byrd, Albert de la Chapelle, Pia Vahteristo

Published Feb 24, 2015 · Vol. 6, No. 3 · pp. 1884-1888

Keywords: Chronic lymphocytic leukemia, MED12, somatic mutation, cancer genetics, prognosis

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo Research Paper

Ulrike Fischer, Christina Backes, Abdulrahman Raslan, Andreas Keller, Carola Meier, Eckart Meese

Published Feb 19, 2015 · Vol. 6, No. 9 · pp. 7023-7039

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Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells Research Paper

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes Research Paper

Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway Research Paper

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer Research Paper

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion Research Paper

Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-Î²/SMAD signaling Research Paper

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers Clinical Research Papers

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis Research Paper

MTH1 expression is required for effective transformation by oncogenic HRAS Research Paper

Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway Research Paper

Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development Research Paper

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma Research Paper

NF2 blocks Snail-mediated p53 suppression in mesothelioma Research Paper

Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach Research Paper

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia Clinical Research Papers

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells Research Paper

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes Research Paper

Involvement of Ras GTPase-activating protein SH3 domain-binding protein 1 in the epithelial-to-mesenchymal transition-induced metastasis of breast cancer cells via the Smad signaling pathway Research Paper

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer Research Paper

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion Research Paper

Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-Î²/SMAD signaling Research Paper

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers Clinical Research Papers

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts Priority Research Paper

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis Research Paper

MTH1 expression is required for effective transformation by oncogenic HRAS Research Paper

Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway Research Paper

Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development Research Paper

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Research Paper

New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma Research Paper

NF2 blocks Snail-mediated p53 suppression in mesothelioma Research Paper

Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach Research Paper

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia Clinical Research Papers

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo Research Paper