The Oncosearch | Oncotarget

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Wei-Yu Chen, Shih-Yang Liu, Yung-Sheng Chang, Juan Juan Yin, Hsiu-lien Yeh, Tarek H. Mouhieddine, Ola Hadadeh, Wassim Abou-Kheir, Yen-Nien Liu

Published Nov 25, 2014 · Vol. 6, No. 1 · pp. 441-457

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Galina Kochneva, Evgeniy Zonov, Antonina Grazhdantseva, Anastasiya Yunusova, Galina Sibolobova, Evgeniy Popov, Oleg Taranov, Sergei Netesov, Peter Chumakov, Elena Ryabchikova

Published Nov 19, 2014 · Vol. 5, No. 22 · pp. 11269-11282

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

Lorena Landuzzi, Marianna L. Ianzano, Giordano Nicoletti, Arianna Palladini, Valentina Grosso, Dario Ranieri, Massimiliano Dallâ€™Ora, Elena Raschi, Roberta Laranga, Marco Gambarotti, Piero Picci, Carla De Giovanni, Patrizia Nanni, Pier-Luigi Lollini

Published Nov 18, 2014 · Vol. 5, No. 23 · pp. 11924-11938

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Ming-Yi Ho, Chi-Ming Liang, Shu-Mei Liang

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 381-393

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Giulia Guzzo, Marco Sciacovelli, Paolo Bernardi, Andrea Rasola

Published Nov 15, 2014 · Vol. 5, No. 23 · pp. 11897-11908

Keywords: TRAP1, mitochondria, chaperones, cancer metabolism, ROS, succinate dehydrogenase

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

Mary E. Gagou, Anil Ganesh, Geraldine Phear, Darren Robinson, Eva Petermann, Angela Cox, Mark Meuth

Published Nov 5, 2014 · Vol. 5, No. 22 · pp. 11381-11398

Keywords: helicases, replication stress, oncogenes, human cells

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

David S. Hong, Razelle Kurzrock, Marilyn Mulay, Erik Rasmussen, Benjamin M. Wu, Michael B. Bass, Zhandong D. Zhong, Greg Friberg, Lee S. Rosen

Published Oct 23, 2014 · Vol. 5, No. 22 · pp. 11154-11167

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Eftychia Oikonomou, Evangelos Koustas, Maria Goulielmaki, Alexander Pintzas

Published Oct 21, 2014 · Vol. 5, No. 23 · pp. 11752-11777

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation Priority Research Paper

Ying Yan, Ashley L. Hein, Asserewou Etekpo, Katrina M. Burchett, Chi Lin, Charles A. Enke, Surinder K. Batra, Kenneth H. Cowan, Michel M. Ouellette

Published Oct 21, 2014 · Vol. 5, No. 21 · pp. 10251-10270

Keywords: ATM/ATR, clonogenic survival, G2 checkpoint, irradiation, radiosensitivity Running title: Rac1 inhibition radiosensitizes pancreatic cancer cells

Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells Research Paper

Hui-Chao Zhou, Jian-Hong Fang, Xu Luo, Lei Zhang, Jine Yang, Chong Zhang, Shi-Mei Zhuang

Published Oct 18, 2014 · Vol. 5, No. 23 · pp. 12177-12188

E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis Research Paper

Sayeda Yasmin-Karim, Michael R. King, Edward M. Messing, Yi-Fen Lee

Published Oct 6, 2014 · Vol. 5, No. 23 · pp. 12097-12110

Keywords: prostate cancer, circulatory tumor cell, cancer cell rolling and adhesion, E-selectin ligand-1, E-selectin

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Xiaodong Zhou, Ling Shen, Toshima Parris, Junchi Huang, Bo Yi, Khalil Helou, Changyan Chen

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10709-10717

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas Priority Research Paper

Jie Li, Zachary J. Taich, Amit Goyal, David Gonda, Johnny Akers, Bandita Adhikari, Kunal Patel, Scott Vandenberg, Wei Yan, Zhaoshi Bao, Bob S. Carter, Renzhi Wang, Ying Mao, Tao Jiang, Clark C. Chen

Published Aug 16, 2014 · Vol. 5, No. 17 · pp. 7342-7356

Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma Research Paper

Yona Goldshmit, Sari Schokoroy Trangle, Yoel Kloog, Ronit Pinkas-Kramarski

Published Aug 12, 2014 · Vol. 5, No. 18 · pp. 8602-8613

Ras in epidermal proliferation Editorial

Matthias Drosten, Carmen G. Lechuga, Mariano Barbacid

Published Aug 1, 2014 · Vol. 5, No. 14 · pp. 5194-5195

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

Frankie Lam, Abdullahi Y. Abbas, Hao Shao, Theodosia Teo, Julian Adams, Peng Li, Tracey D. Bradshaw, Peter M. Fischer, Elisabeth Walsby, Chris Pepper, Yi Chen, Jian Ding, Shudong Wang

Published Jul 31, 2014 · Vol. 5, No. 17 · pp. 7691-7704

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis Research Paper

Yuting Huang, Meng Zhao, Haixu Xu, Ke Wang, Zheng Fu, Yuan Jiang, Zhi Yao

Published Jul 23, 2014 · Vol. 5, No. 16 · pp. 6734-6745

The NF1 gene revisited â€“ from bench to bedside Review

Yoon-Sim Yap, John R. McPherson, Choon-Kiat Ong, Steven G. Rozen, Bin-Tean Teh, Ann S. G. Lee, David F. Callen

Published Jul 9, 2014 · Vol. 5, No. 15 · pp. 5873-5892

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

Boh-Ram Kim, Kyungsil Yoon, Hyun-Jung Byun, Seung Hee Seo, Seung-Hoon Lee, Seung Bae Rho

Published Jun 19, 2014 · Vol. 5, No. 15 · pp. 6540-6551

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma Research Paper

Lin Wang, Zhu-mei Shi, Cheng-fei Jiang, Xue Liu, Qiu-dan Chen, Xu Qian, Dong-mei Li, Xin Ge, Xie-feng Wang, Ling-Zhi Liu, Yong-ping You, Ning Liu, Bing-Hua Jiang

Published Jun 18, 2014 · Vol. 5, No. 14 · pp. 5416-5427

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MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation Priority Research Paper

Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells Research Paper

E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis Research Paper

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas Priority Research Paper

Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma Research Paper

Ras in epidermal proliferation Editorial

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis Research Paper

The NF1 gene revisited â€“ from bench to bedside Review

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis Research Paper

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications Review

Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation Priority Research Paper

Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells Research Paper

E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis Research Paper

Regulation of the viability of Nf1 deficient cells by PKC isoforms Research Paper

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas Priority Research Paper

Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma Research Paper

Ras in epidermal proliferation Editorial

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73 Research Paper

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis Research Paper

The NF1 gene revisited â€“ from bench to bedside Review

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma Research Paper