The Oncosearch | Oncotarget

Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

Carminia Maria Della Corte, Vincenza Ciaramella, Concetta Di Mauro, Maria Domenica Castellone, Federica Papaccio, Morena Fasano, Ferdinando Carlo Sasso, Erika Martinelli, Teresa Troiani, Ferdinando De Vita, Michele Orditura, Roberto Bianco, Fortunato Ciardiello, Floriana Morgillo

Published Dec 11, 2015 · Vol. 7, No. 4 · pp. 4265-4278

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

Zhongqian Hu, Xinyi Wang, Haoshu Fang, Yakun Liu, Danlei Chen, Qian Zhang, Xia Liu, Daoyan Wei, Chengkui Qu, Siying Wang

Published Dec 10, 2015 · Vol. 7, No. 5 · pp. 5664-5676

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

Bo-Liang Liu, Kai-Xuan Sun, Zhi-Hong Zong, Shuo Chen, Yang Zhao

Published Dec 9, 2015 · Vol. 7, No. 6 · pp. 6649-6664

MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1 Research Paper

Lin Wang, Cheng-fei Jiang, Dong-mei Li, Xin Ge, Zhu-mei Shi, Chong-yong Li, Xue Liu, Yu Yin, Linlin Zhen, Ling-Zhi Liu, Bing-Hua Jiang

Published Dec 9, 2015 · Vol. 7, No. 3 · pp. 2660-2671

DAB2IP in cancer Review

Liang Liu, Cong Xu, Jer-Tsong Hsieh, Jianping Gong, Daxing Xie

Published Dec 8, 2015 · Vol. 7, No. 4 · pp. 3766-3776

RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action Review

Julien Masliah-Planchon, Simon Garinet, Eric Pasmant

Published Dec 5, 2015 · Vol. 7, No. 25 · pp. 38892-38907

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Serguei A. Gordeev, Tatiana V. Bykova, Svetlana G. Zubova, Olga A. Bystrova, Marina G. Martynova, Valery A. Pospelov, Tatiana V. Pospelova

Published Dec 4, 2015 · Vol. 6, No. 42 · pp. 44905-44926

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway Research Paper

Manoj K. Kashyap, Deepak Kumar, Harrison Jones, Carlos I. Amaya-Chanaga, Michael Y. Choi, Johanna Melo-Cardenas, Amine Ale-Ali, Michelle R. Kuhne, Peter Sabbatini, Lewis J. Cohen, Suresh G. Shelat, Laura Z. Rassenti, Thomas J. Kipps, Pina M. Cardarelli, Januario E. Castro

Published Dec 4, 2015 · Vol. 7, No. 3 · pp. 2809-2822

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism Research Paper

Erica Torchiaro, Annalisa Lorenzato, Martina Olivero, Donatella Valdembri, Paolo Armando Gagliardi, Marta Gai, Jessica Erriquez, Guido Serini, Maria Flavia Di Renzo

Published Nov 26, 2015 · Vol. 7, No. 1 · pp. 712-728

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Namrata Rastogi, Shivali Duggal, Shailendra Kumar Singh, Konica Porwal, Vikas Kumar Srivastava, Rakesh Maurya, Madan L.B. Bhatt, Durga Prasad Mishra

Published Nov 25, 2015 · Vol. 6, No. 41 · pp. 43310-43325

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Renata Duchnowska, Piotr J. Wysocki, Konstanty Korski, BogumiÅ‚a Czartoryska- ArÅ‚ukowicz, Anna NiwiÅ„ska, Marlena Orlikowska, Barbara Radecka, Maciej StudziÅ„ski, Regina Demlova, Barbara ZiÃ³Å‚kowska, Monika Merdalska, Åukasz Hajac, Paulina MyÅ›liwiec, Dorota Zuziak, Sylwia DÄ™bska-Szmich, Istvan Lang, MaÅ‚gorzata FoszczyÅ„ska-KÅ‚oda, BoÅ¼enna Karczmarek-Borowska, Anton Å»awrocki, Anna Kowalczyk, Wojciech Biernat, Jacek Jassem, for the Central and East European Oncology Group (CEEOG)

Published Nov 24, 2015 · Vol. 7, No. 1 · pp. 550-564

Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras Priority Research Paper

Suhyun Sung, Jungwon Choi, Heesun Cheong

Published Nov 14, 2015 · Vol. 6, No. 38 · pp. 40405-40417

Mutant HRAS as novel target for MEK and mTOR inhibitors Research Paper

Michael K. Kiessling, Alessandra Curioni-Fontecedro, Panagiotis Samaras, Kirstin Atrott, Jesus Cosin-Roger, Silvia Lang, Michael Scharl, Gerhard Rogler

Published Nov 3, 2015 · Vol. 6, No. 39 · pp. 42183-42196

Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription Research Paper

Yang Gao, Kaijie Wu, Yule Chen, Jiancheng Zhou, Chong Du, Qi Shi, Shan Xu, Jing Jia, Xiaoshuang Tang, Feng Li, Ke Hui, Dalin He, Peng Guo

Published Oct 31, 2015 · Vol. 6, No. 41 · pp. 43791-43805

Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network Research Paper

Jin Zhu, Sugui Wang, Wenyu Zhang, Junyi Qiu, Yuxi Shan, Dongrong Yang, Bairong Shen

Published Oct 31, 2015 · Vol. 6, No. 41 · pp. 43819-43830

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

Dawei Chen, Xuesong Huang, Jie Cai, Sheng Guo, Wubin Qian, Jean-Pierre Wery, Qi-Xiang Li

Published Oct 26, 2015 · Vol. 6, No. 38 · pp. 40815-40821

Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance Research Paper

Jie Sun, Qi Shen, Haiqi Lu, Zhinong Jiang, Wenxia Xu, Lifeng Feng, Ling Li, Xian Wang, Xiujun Cai, Hongchuan Jin

Published Oct 24, 2015 · Vol. 6, No. 39 · pp. 41997-42007

MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab Research Paper

Jitka Mlcochova, Petra Faltejskova-Vychytilova, Manuela Ferracin, Barbara Zagatti, Lenka Radova, Marek Svoboda, Radim Nemecek, Stanislav John, Igor Kiss, Rostislav Vyzula, Massimo Negrini, Ondrej Slaby

Published Oct 20, 2015 · Vol. 6, No. 36 · pp. 38695-38704

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Keyata N. Thompson, Rebecca A. Whipple, Jennifer R. Yoon, Michael Lipsky, Monica S. Charpentier, Amanda E. Boggs, Kristi R. Chakrabarti, Lekhana Bhandary, Lindsay K. Hessler, Stuart S. Martin, Michele I. Vitolo

Published Oct 19, 2015 · Vol. 6, No. 34 · pp. 35231-35246

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes Research Paper

Sally M. Hunter, Michael S. Anglesio, Georgina L. Ryland, Raghwa Sharma, Yoke-Eng Chiew, Simone M. Rowley, Maria A. Doyle, Jason Li, C. Blake Gilks, Phillip Moss, Prue E. Allan, Andrew N. Stephens, David G. Huntsman, Anna deFazio, David D. Bowtell, Australian Ovarian Cancer Study Group, Kylie L. Gorringe, Ian G. Campbell

Published Oct 19, 2015 · Vol. 6, No. 35 · pp. 37663-37677

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Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1 Research Paper

DAB2IP in cancer Review

RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action Review

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway Research Paper

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras Priority Research Paper

Mutant HRAS as novel target for MEK and mTOR inhibitors Research Paper

Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription Research Paper

Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network Research Paper

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance Research Paper

MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab Research Paper

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells Research Paper

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma Research Paper

MicroRNA-372 inhibits endometrial carcinoma development by targeting the expression of the Ras homolog gene family member C (RhoC) Research Paper

MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1 Research Paper

DAB2IP in cancer Review

RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action Review

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway Research Paper

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients Research Paper

Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras Priority Research Paper

Mutant HRAS as novel target for MEK and mTOR inhibitors Research Paper

Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription Research Paper

Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network Research Paper

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance Research Paper

MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab Research Paper

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence Priority Research Paper

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes Research Paper