The Oncosearch | Oncotarget

H-Ras regulation of TRAIL death receptor mediated apoptosis Research Paper

Jun-Jie Chen, William P. Bozza, Xu Di, Yaqin Zhang, William Hallett, Baolin Zhang

Published Jun 11, 2014 · Vol. 5, No. 13 · pp. 5125-5137

Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

Masashi Okada, Keita Shibuya, Atsushi Sato, Shizuka Seino, Shuhei Suzuki, Manabu Seino, Chifumi Kitanaka

Published Jun 10, 2014 · Vol. 5, No. 13 · pp. 5100-5112

The MAPK pathway as an apoptosis enhancer in melanoma Research Paper

Johannes M. Haydn, Anita Hufnagel, Johannes Grimm, Katja Maurus, Manfred Schartl, Svenja Meierjohann

Published Jun 8, 2014 · Vol. 5, No. 13 · pp. 5040-5053

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

Martina Olivero, Daniela Dettori, Sabrina Arena, Davide Zecchin, Erica Lantelme, Maria Flavia Di Renzo

Published May 30, 2014 · Vol. 5, No. 15 · pp. 5992-6002

GSK-3 as potential target for therapeutic intervention in cancer Review

James A. McCubrey, Linda S. Steelman, Fred E. Bertrand, Nicole M. Davis, Melissa Sokolosky, Steve L. Abrams, Giuseppe Montalto, Antonino B. Dâ€™Assoro, Massimo Libra, Ferdinando Nicoletti, Roberta Maestro, Jorg Basecke, Dariusz Rakus, Agnieszka Gizak, Zoya Demidenko, Lucio Cocco, Alberto M. Martelli, Melchiorre Cervello

Published May 28, 2014 · Vol. 5, No. 10 · pp. 2881-2911

Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Research Paper

Maria Grazia Vizioli, Joana Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco A. Pierotti, Jesus Gil, Angela Greco

Published May 26, 2014 · Vol. 5, No. 18 · pp. 8270-8283

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Anna PastÃ², Chiara Bellio, Giorgia Pilotto, Vincenzo Ciminale, Micol Silic-Benussi, Giulia Guzzo, Andrea Rasola, Chiara Frasson, Giorgia Nardo, Elisabetta Zulato, Maria Ornella Nicoletto, Mariangela Manicone, Stefano Indraccolo, Alberto Amadori

Published May 26, 2014 · Vol. 5, No. 12 · pp. 4305-4319

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Xiaomei Qi, Congying Xie, Songwang Hou, Gang Li, Ning Yin, Lei Dong, Adrienne Lepp, Marla A. Chesnik, Shama P. Mirza, Aniko Szabo, Susan Tsai, Zainab Basir, Shixiu Wu, Guan Chen

Published May 25, 2014 · Vol. 5, No. 12 · pp. 4269-4282

Negative regulation of DAB2IP by Akt and SCF^Fbw7 pathways Research Paper

Xiangpeng Dai, Brian J. North, Hiroyuki Inuzuka

Published May 1, 2014 · Vol. 5, No. 10 · pp. 3307-3315

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

Yair Tal, Shlomo Yaakobi, Miryam Horovitz-Fried, Einav Safyon, Benyamin Rosental, Angel Porgador, Cyrille J. Cohen

Published Apr 24, 2014 · Vol. 5, No. 21 · pp. 10949-10958

CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response Research Paper

Laura P. Saucedo-Cuevas, Isabel Ruppen, Pilar XimÃ©nez-EmbÃºn, Samuel Domingo, Javier Gayarre, Javier MuÃ±oz, Jose M. Silva, MarÃa J. GarcÃa, Javier BenÃtez

Published Apr 18, 2014 · Vol. 5, No. 8 · pp. 2330-2343

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649) Research Paper

Stian Knappskog, Liv B. Gansmo, Khadizha Dibirova, Andres Metspalu, Cezary Cybulski, Paolo Peterlongo, Lauri Aaltonen, Lars Vatten, PÃ¥l Romundstad, Kristian Hveem, Peter Devilee, Gareth D. Evans, Dongxin Lin, Guy Van Camp, Vangelis G. Manolopoulos, Ana Osorio, Lili Milani, Tayfun Ozcelik, Pierre Zalloua, Francis Mouzaya, Elena Bliznetz, Elena Balanovska, Elvira Pocheshkova, Vaidutis KuÄinskas, Lubov Atramentova, Pagbajabyn Nymadawa, Konstantin Titov, Maria Lavryashina, Yuldash Yusupov, Natalia Bogdanova, Sergey Koshel, Jorge Zamora, David C. Wedge, Deborah Charlesworth, Thilo DÃ¶rk, Oleg Balanovsky, Per E. LÃ¸nning

Published Apr 18, 2014 · Vol. 5, No. 18 · pp. 8223-8234

MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis Research Paper

Hui-jie Huang, Jun Liu, Hu Hua, San-en Li, Jin Zhao, Shen Yue, Ting-ting Yu, Yu-cui Jin, Steven Y. Cheng

Published Mar 25, 2014 · Vol. 5, No. 8 · pp. 2161-2175

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Jie Li, Shan Zhu, David Kozono, Kimberly Ng, Diahnn Futalan, Ying Shen, Johnny C. Akers, Tyler Steed, Deepa Kushwaha, Michael Schlabach, Bob S. Carter, Chang-Hyuk Kwon, Frank Furnari, Webster Cavenee, Stephen Elledge, Clark C. Chen

Published Mar 7, 2014 · Vol. 5, No. 4 · pp. 882-893

Ras and autophagy in cancer development and therapy. Review

Eran Schmukler, Yoel Kloog, Ronit Pinkas-Kramarski

Published Feb 13, 2014 · Vol. 5, No. 3 · pp. 577-586

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Patrick J. Killela, Christopher J. Pirozzi, Patrick Healy, Zachary J. Reitman, Eric Lipp, Ahmed B. Rasheed, Rui Yang, Bill H. Diplas, Zhaohui Wang, Paula K. Greer, Huishan Zhu, Catherine Y. Wang, Austin B. Carpenter, Henry Friedman, Allan H. Friedman, Stephen T. Keir, Jie He, Yiping He, Roger E. McLendon, James E. Herndon II, Hai Yan, Darell D. Bigner

Published Jan 28, 2014 · Vol. 5, No. 6 · pp. 1515-1525

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

Annalucia Serafino, Noemi Moroni, Manuela Zonfrillo, Federica Andreola, Luana Mercuri, Giuseppe Nicotera, Joseph Nunziata, Riccardo Ricci, Armando Antinori, Guido Rasi, Pasquale Pierimarchi

Published Jan 11, 2014 · Vol. 5, No. 4 · pp. 978-992

Keywords: Wnt/Î²-catenin pathway, Colorectal carcinogenesis, Inflammatory Bowel Disease, Diagnostic/therapeutic biomarkers, Multiparametric analysis

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

Ya-ling Tang, Yun-long Fan, Jian Jiang, Kai-de Li, Min Zheng, Wei Chen, Xiang-rui Ma, Ning Geng, Qian-ming Chen, Yu Chen, Xinhua Liang

Published Jan 6, 2014 · Vol. 5, No. 6 · pp. 1491-1501

Keywords: salivary adenoid cystic cancer, epithelialâ€“mesenchymal transition (EMT), c-kit, cancer stem cell, metastasis

SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I Research Paper

Francesco Ciscato, Marco Sciacovelli, Gianmarco Villano, Cristian Turato, Paolo Bernardi, Andrea Rasola, Patrizia Pontisso

Published Dec 24, 2013 · Vol. 5, No. 9 · pp. 2418-2427

Keywords: SERPINB3, chemotherapeutics, mitochondria, respiratory complexes, reactive oxygen species, cell death

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Sun-Hye Lee, Tae-Gyun Woo, Su-Jin Lee, Nam-Chul Ha, Bum-Joon Park

Published Dec 2, 2013 · Vol. 4, No. 12 · pp. 2523-2531

Keywords: p53 core domain, Oncogenic K-Ras, Caveolin-1, Drug delivery

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H-Ras regulation of TRAIL death receptor mediated apoptosis Research Paper

Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

The MAPK pathway as an apoptosis enhancer in melanoma Research Paper

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Research Paper

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Negative regulation of DAB2IP by Akt and SCF^Fbw7 pathways Research Paper

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response Research Paper

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649) Research Paper

MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis Research Paper

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Ras and autophagy in cancer development and therapy. Review

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

H-Ras regulation of TRAIL death receptor mediated apoptosis Research Paper

Targeting the K-Ras - JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation Research Paper

The MAPK pathway as an apoptosis enhancer in melanoma Research Paper

The stress phenotype makes cancer cells addicted to CDT2, a substrate receptor of the CRL4 ubiquitin ligase Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Research Paper

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Negative regulation of DAB2IP by Akt and SCFFbw7 pathways Research Paper

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities Research Paper

CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response Research Paper

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649) Research Paper

MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis Research Paper

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma Priority Research Paper

Ras and autophagy in cancer development and therapy. Review

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I Research Paper

Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system Research Paper

Negative regulation of DAB2IP by Akt and SCF^Fbw7 pathways Research Paper