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Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment Research Paper

Maren Bredemeier, Philippos Edimiris, Mitra Tewes, Pawel Mach, Bahriye Aktas, Doreen Schellbach, Jenny Wagner, Rainer Kimmig, Sabine Kasimir-Bauer

Published May 20, 2016 · Vol. 7, No. 27 · pp. 41677-41690

Venous malformations: PIK3CA mutations guide new treatments Editorial

Hashem A. Dbouk

Published May 9, 2016 · Vol. 7, No. 31 · pp. 48852-48853

Genetic alteration profiling of patients with resected squamous cell lung carcinomas Research Paper

Dan Tao, Xiaohong Han, Ningning Zhang, Dongmei Lin, Di Wu, Xinxin Zhu, Wenya Song, Yuankai Shi

Published Apr 29, 2016 · Vol. 7, No. 24 · pp. 36590-36601

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting Research Paper

George Fountzilas, Eleni Giannoulatou, Zoi Alexopoulou, Flora Zagouri, Eleni Timotheadou, Kyriaki Papadopoulou, Sotiris Lakis, Mattheos Bobos, Christos Poulios, Maria Sotiropoulou, Aggeliki Lyberopoulou, Helen Gogas, George Pentheroudakis, Dimitrios Pectasides, Angelos Koutras, Christos Christodoulou, Christos Papandreou, Epaminontas Samantas, Pavlos Papakostas, Paris Kosmidis, Dimitrios Bafaloukos, Charisios Karanikiotis, Meletios-Athanassios Dimopoulos, Vassiliki Kotoula

Published Apr 26, 2016 · Vol. 7, No. 22 · pp. 32731-32753

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas Research Paper

DarÃo GarcÃa-Carracedo, Maria Ãngeles Villaronga, SaÃºl Ãlvarez-Teijeiro, Francisco Hermida-Prado, IÃ±igo SantamarÃa, Eva Allonca, Laura SuÃ¡rez-FernÃ¡ndez, Maria Victoria Gonzalez, Milagros BalbÃn, Aurora Astudillo, Pablo MartÃnez-Camblor, Gloria H. Su, Juan Pablo Rodrigo, Juana MarÃa GarcÃa-Pedrero

Published Apr 23, 2016 · Vol. 7, No. 20 · pp. 29780-29793

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium) Research Paper

Sun Min Lim, Hye Ryun Kim, Eun Kyung Cho, Young Joo Min, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Byoung Chul Cho, Ji-Hyun Lee, Hye Cheol Jeong, Eun Kyung Kim, Joo-Hang Kim

Published Apr 21, 2016 · Vol. 7, No. 24 · pp. 36311-36320

Genetic changes of non-small cell lung cancer under neoadjuvant therapy Research Paper

Arne Warth, Volker Endris, Albrecht Stenzinger, Roland Penzel, Alexander Harms, Thomas Duell, Amir Abdollahi, Michael Lindner, Peter Schirmacher, Thomas Muley, Hendrik Dienemann, Ludger Fink, Alicia Morresi-Hauf, Nicole Pfarr, Wilko Weichert

Published Apr 20, 2016 · Vol. 7, No. 20 · pp. 29761-29769

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma Research Paper

Hyo Song Kim, Seung Eun Lee, Yoon Sung Bae, Dae Joon Kim, Chang Geol Lee, Jin Hur, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Hye Ryun Kim, Young Mog Shim, Susan S. Jewell, Hyunki Kim, Yoon-La Choi, Byoung Chul Cho

Published Apr 15, 2016 · Vol. 7, No. 21 · pp. 30691-30701

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway Research Paper

Mileidys PÃ©rez-Alea, Ana Vivancos, Ginevra CaratÃº, Judit Matito, Berta Ferrer, Javier Hernandez-Losa, Javier CortÃ©s, Eva MuÃ±oz, Vicente Garcia-Patos, Juan A. Recio

Published Apr 4, 2016 · Vol. 7, No. 19 · pp. 28086-28095

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies Research Paper

Muhammad Zaki Hidayatullah Fadlullah, Ivy Kim-Ni Chiang, Kalen R. Dionne, Pei San Yee, Chai Phei Gan, Kin Kit Sam, Kai Hung Tiong, Adrian Kwok Wen Ng, Daniel Martin, Kue Peng Lim, Thomas George Kallarakkal, Wan Mahadzir Wan Mustafa, Shin Hin Lau, Mannil Thomas Abraham, Rosnah Binti Zain, Zainal Ariff Abdul Rahman, Alfredo Molinolo, Vyomesh Patel, J. Silvio Gutkind, Aik Choon Tan, Sok Ching Cheong

Published Apr 1, 2016 · Vol. 7, No. 19 · pp. 27802-27818

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response Research Paper

Zhe-Zhen Li, Feng Wang, Zi-Chen Zhang, Fang Wang, Qi Zhao, Dong-Sheng Zhang, Feng-Hua Wang, Zhi-Qiang Wang, Hui-Yan Luo, Ming-Ming He, De-Shen Wang, Ying Jin, Chao Ren, Miao-Zhen Qiu, Jian Ren, Zhi-Zhong Pan, Yu-Hong Li, Jiao-Yong Shao, Rui-Hua Xu

Published Apr 1, 2016 · Vol. 7, No. 19 · pp. 28356-28368

Comparative genomic analysis of primary tumors and metastases in breast cancer Research Paper

FranÃ§ois Bertucci, Pascal Finetti, Arnaud Guille, JosÃ© AdÃ©laÃ¯de, SÃ©verine Garnier, Nadine Carbuccia, Audrey Monneur, Emmanuelle Charafe-Jauffret, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Max Chaffanet

Published Mar 25, 2016 · Vol. 7, No. 19 · pp. 27208-27219

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

Jean-Philippe Foy, Antonin Tortereau, Carlos Caulin, Vincent Le Texier, Emilie Lavergne, Emilie Thomas, Sylvie Chabaud, David Perol, JoÃ«l Lachuer, Wenhua Lang, Waun Ki Hong, Patrick Goudot, Scott M. Lippman, ChloÃ© Bertolus, Pierre Saintigny

Published Mar 24, 2016 · Vol. 7, No. 24 · pp. 35932-35945

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

Yaqing Chen, Jianchang Qian, Qun He, Hui Zhao, Lourdes Toral-Barza, Celine Shi, Xuesai Zhang, Jiang Wu, Ker Yu

Published Mar 22, 2016 · Vol. 7, No. 18 · pp. 25224-25240

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma Research Paper

Joo Hoon Kim, Jae Seok Lee, Eo Jin Kim, Kyu Hyun Park, Ki Hyang Kim, Seong Yoon Yi, Han Seong Kim, Yong Jin Cho, Kyoo-Ho Shin, Joong Bae Ahn, Hyuk Hu, Kyung Sik Kim, Young Deuk Choi, Sunghoon Kim, Young Han Lee, Jin-Suck Suh, Sung Hoon Noh, Sun Young Rha, Hyo Song Kim

Published Mar 21, 2016 · Vol. 7, No. 17 · pp. 24549-24558

Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients Research Paper

Eric Deutsch, Christine Haie-Meder, Mohamed Amine Bayar, Michele Mondini, MÃ©lanie Laporte, Renaud Mazeron, Julien Adam, Andrea Varga, Gilles Vassal, Nicolas MagnÃ©, Cyrus Chargari, Emilie Lanoy, Patricia Pautier, Antonin Levy, Jean-Charles Soria

Published Mar 21, 2016 · Vol. 7, No. 18 · pp. 25549-25557

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis Priority Research Paper

Maria L. Mancini, Evan C. Lien, Alex Toker

Published Mar 18, 2016 · Vol. 7, No. 14 · pp. 17301-17313

PD-L1 is an independent prognostic predictor in gastric cancer of Western patients Research Paper

Christine BÃ¶ger, Hans-Michael Behrens, Micaela Mathiak, Sandra KrÃ¼ger, Holger Kalthoff, Christoph RÃ¶cken

Published Mar 18, 2016 · Vol. 7, No. 17 · pp. 24269-24283

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients Research Paper

Hung-Chih Hsu, Tan Kien Thiam, Yen-Jung Lu, Chien Yuh Yeh, Wen-Sy Tsai, Jeng Fu You, Hsin Yuan Hung, Chi-Neu Tsai, An Hsu, Hua-Chien Chen, Shu-Jen Chen, Tsai-Sheng Yang

Published Mar 12, 2016 · Vol. 7, No. 16 · pp. 22257-22270

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics Research Paper

Philip R. Cohen, Brett N. Tomson, Sheryl K. Elkin, Erica Marchlik, Jennifer L. Carter, Razelle Kurzrock

Published Mar 10, 2016 · Vol. 7, No. 17 · pp. 23454-23467

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Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment Research Paper

Venous malformations: PIK3CA mutations guide new treatments Editorial

Genetic alteration profiling of patients with resected squamous cell lung carcinomas Research Paper

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting Research Paper

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas Research Paper

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium) Research Paper

Genetic changes of non-small cell lung cancer under neoadjuvant therapy Research Paper

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma Research Paper

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway Research Paper

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies Research Paper

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response Research Paper

Comparative genomic analysis of primary tumors and metastases in breast cancer Research Paper

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma Research Paper

Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients Research Paper

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis Priority Research Paper

PD-L1 is an independent prognostic predictor in gastric cancer of Western patients Research Paper

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients Research Paper

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment Research Paper

Venous malformations: PIK3CA mutations guide new treatments Editorial

Genetic alteration profiling of patients with resected squamous cell lung carcinomas Research Paper

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting Research Paper

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas Research Paper

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium) Research Paper

Genetic changes of non-small cell lung cancer under neoadjuvant therapy Research Paper

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma Research Paper

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway Research Paper

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies Research Paper

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response Research Paper

Comparative genomic analysis of primary tumors and metastases in breast cancer Research Paper

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer Research Paper

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma Research Paper

Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients Research Paper

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis Priority Research Paper

PD-L1 is an independent prognostic predictor in gastric cancer of Western patients Research Paper

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients Research Paper

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics Research Paper