The Oncosearch | Oncotarget

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology Research Paper

Maider Ibarrola-Villava, Tania Fleitas, Marta J. Llorca-CardeÃ±osa, Cristina Mongort, Elisa Alonso, Samuel Navarro, Octavio Burgues, Ana Vivancos, Juan Miguel Cejalvo, JosÃ© Alejandro Perez-Fidalgo, Susana RosellÃ³, Gloria Ribas, AndrÃ©s Cervantes

Published Mar 9, 2016 · Vol. 7, No. 16 · pp. 22543-22555

Survival kinase genes present prognostic significance in glioblastoma Research Paper

Robin T. Varghese, Yanping Liang, Ting Guan, Christopher T. Franck, Deborah F. Kelly, Zhi Sheng

Published Mar 4, 2016 · Vol. 7, No. 15 · pp. 20140-20151

Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Doris Helbig, Michaela Angelika Ihle, Katharina PÃ¼tz, Iliana Tantcheva-Poor, Cornelia Mauch, Reinhard BÃ¼ttner, Alexander Quaas

Published Mar 2, 2016 · Vol. 7, No. 16 · pp. 21763-21774

Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy Research Paper

MylÃ¨ne Sebagh, Marc-Antoine Allard, Nelly Bosselut, Myriam Dao, Eric Vibert, MaÃ¯tÃ© Lewin, Antoinette Lemoine, Daniel Cherqui, RenÃ© Adam, Antonio Sa Cunha

Published Mar 1, 2016 · Vol. 7, No. 16 · pp. 21591-21600

Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer Research Paper

Dong Wang, Min Wang, Nan Jiang, Yuan Zhang, Xing Bian, Xiaoqing Wang, Thomas M. Roberts, Jean J. Zhao, Pixu Liu, Hailing Cheng

Published Feb 21, 2016 · Vol. 7, No. 11 · pp. 13153-13166

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment Research Paper

Haa-Na Song, Chung Lee, Seung Tae Kim, Sun Young Kim, Nayoung K.D. Kim, Jiryeon Jang, Mihyun Kang, Hyojin Jang, Soomin Ahn, Seok Hyeong Kim, Yoona Park, Yong Beom Cho, Jeong Wook Heo, Woo Yong Lee, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park, Woong-Yang Park, Jeeyun Lee, Hee Cheol Kim

Published Feb 20, 2016 · Vol. 7, No. 15 · pp. 19610-19619

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA⁺ oral cancers Priority Research Paper

Kosuke Yamaguchi, Ramiro Iglesias-BartolomÃ©, Zhiyong Wang, Juan Luis Callejas-Valera, Panomwat Amornphimoltham, Alfredo A. Molinolo, Ezra E. Cohen, Joseph A. Califano, Scott M. Lippman, Ji Luo, J. Silvio Gutkind

Published Feb 13, 2016 · Vol. 7, No. 10 · pp. 10696-10709

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer Research Paper

Marco Lo Iacono, Consuelo Buttigliero, Valentina Monica, Enrico Bollito, Diletta Garrou, Susanna Cappia, Ida Rapa, Francesca Vignani, Valentina Bertaglia, Cristian Fiori, Mauro Papotti, Marco Volante, Giorgio V. Scagliotti, Francesco Porpiglia, Marcello Tucci

Published Feb 12, 2016 · Vol. 7, No. 12 · pp. 14394-14404

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

Sun Min Lim, Hyung Soon Park, Sangwoo Kim, Sora Kim, Siraj M. Ali, Joel R. Greenbowe, In Seok Yang, Nak-Jung Kwon, Jae Lyun Lee, Min-Hee Ryu, Jin-Hee Ahn, Jeeyun Lee, Min Goo Lee, Hyo Song Kim, Hyunki Kim, Hye Ryun Kim, Yong Wha Moon, Hyun Cheol Chung, Joo-Hang Kim, Yoon-Koo Kang, Byoung Chul Cho

Published Feb 7, 2016 · Vol. 7, No. 9 · pp. 10547-10556

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

Shang-Gin Wu, Yi-Nan Liu, Meng-Feng Tsai, Yih-Leong Chang, Chong-Jen Yu, Pan-Chyr Yang, James Chih-Hsin Yang, Yueh-Feng Wen, Jin-Yuan Shih

Published Feb 4, 2016 · Vol. 7, No. 11 · pp. 12404-12413

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response Research Paper

Rosamaria Pinto, Simona De Summa, Sabino Strippoli, Brunella Pilato, Amalia Azzariti, Gabriella Guida, Michele Guida, Stefania Tommasi

Published Feb 3, 2016 · Vol. 7, No. 18 · pp. 25135-25149

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay Research Paper

Maria Schwaederle, Hatim Husain, Paul T. Fanta, David E. Piccioni, Santosh Kesari, Richard B. Schwab, Kimberly C. Banks, Richard B. Lanman, AmirAli Talasaz, Barbara A. Parker, Razelle Kurzrock

Published Feb 1, 2016 · Vol. 7, No. 9 · pp. 9707-9717

Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation Research Paper

Jeff C. Liu, Dong-Yu Wang, Sean E. Egan, Eldad Zacksenhaus

Published Jan 22, 2016 · Vol. 7, No. 8 · pp. 9060-9068

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

Byungho Lim, Chan Kim, Jeong-Hwan Kim, Woo Sun Kwon, Won Seok Lee, Jeong Min Kim, Jun Yong Park, Hyo Song Kim, Kyu Hyun Park, Tae Soo Kim, Jong-Lyul Park, Hyun Cheol Chung, Sun Young Rha, Seon-Young Kim

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8055-8066

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

Maria Goulielmaki, Evangelos Koustas, Eirini Moysidou, Margarita Vlassi, Takehiko Sasazuki, Senji Shirasawa, George Zografos, Eftychia Oikonomou, Alexander Pintzas

Published Jan 18, 2016 · Vol. 7, No. 8 · pp. 9188-9221

Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers Research Paper

Wen-Liang Fang, Kuo-Hung Huang, Yuan-Tzu Lan, Chien-Hsing Lin, Shih- Ching Chang, Ming-Huang Chen, Yee Chao, Wen-Chang Lin, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Shih-Hwa Chiou, Yi-Ming Shyr

Published Dec 17, 2015 · Vol. 7, No. 5 · pp. 6201-6220

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Gerald Goh, Trent Walradt, Vladimir Markarov, Astrid Blom, Nadeem Riaz, Ryan Doumani, Krista Stafstrom, Ata Moshiri, Lola Yelistratova, Jonathan Levinsohn, Timothy A. Chan, Paul Nghiem, Richard P. Lifton, Jaehyuk Choi

Published Dec 7, 2015 · Vol. 7, No. 3 · pp. 3403-3415

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast Research Paper

Zoran Gatalica, Semir Vranic, Anatole Ghazalpour, Joanne Xiu, Idris Tolgay Ocal, John McGill, Ryan P. Bender, Erin Discianno, Aaron Schlum, Souzan Sanati, Juan Palazzo, Sandeep Reddy, Barbara Pockaj

Published Nov 28, 2015 · Vol. 7, No. 2 · pp. 1707-1716

Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China Clinical Research Papers

Bin Song, Heyang Cui, Yaoping Li, Caixia Cheng, Bin Yang, Fang Wang, Pengzhou Kong, Hongyi Li, Ling Zhang, Zhiwu Jia, Yanghui Bi, Jiaqian Wang, Yong Zhou, Jing Liu, Juan Wang, Zhenxiang Zhao, Yanyan Zhang, Xiaoling Hu, Ruyi Shi, Jie Yang, Haiyan Liu, Ting Yan, Yike Li, Enwei Xu, Yu Qian, Yanfeng Xi, Shiping Guo, Yunqing Chen, Jinfen Wang, Guodong Li, Jianfang Liang, Junmei Jia, Xing Chen, Jiansheng Guo, Tong Wang, Yanbo Zhang, Qingshan Li, Chuangui Wang, Xiaolong Cheng, Qimin Zhan, Yongping Cui

Published Oct 29, 2015 · Vol. 7, No. 3 · pp. 3599-3613

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

Dawei Chen, Xuesong Huang, Jie Cai, Sheng Guo, Wubin Qian, Jean-Pierre Wery, Qi-Xiang Li

Published Oct 26, 2015 · Vol. 6, No. 38 · pp. 40815-40821

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology Research Paper

Survival kinase genes present prognostic significance in glioblastoma Research Paper

Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy Research Paper

Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer Research Paper

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment Research Paper

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA⁺ oral cancers Priority Research Paper

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer Research Paper

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response Research Paper

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay Research Paper

Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation Research Paper

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast Research Paper

Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China Clinical Research Papers

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology Research Paper

Survival kinase genes present prognostic significance in glioblastoma Research Paper

Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Evidence of intermetastatic heterogeneity for pathological response and genetic mutations within colorectal liver metastases following preoperative chemotherapy Research Paper

Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer Research Paper

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment Research Paper

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers Priority Research Paper

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer Research Paper

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus Research Paper

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients Research Paper

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response Research Paper

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay Research Paper

Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation Research Paper

Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites Research Paper

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers Research Paper

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy Research Paper

Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast Research Paper

Mutually exclusive mutations in NOTCH1 and PIK3CA associated with clinical prognosis and chemotherapy responses of esophageal squamous cell carcinoma in China Clinical Research Papers

A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patient-derived xenograft than KRAS 12/13 mutations Research Paper

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA⁺ oral cancers Priority Research Paper