The Oncosearch | Oncotarget

Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics Research Paper

Aliccia Bollig-Fischer, Sharon K. Michelhaugh, Priyanga Wijesinghe, Greg Dyson, Adele Kruger, Nallasivam Palanisamy, Lydia Choi, Baraa Alosh, Rouba Ali-Fehmi, Sandeep Mittal

Published Apr 24, 2015 · Vol. 6, No. 16 · pp. 14614-14624

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Anish Thomas, Yuanbin Chen, Seth M. Steinberg, Ji Luo, Svetlana Pack, Mark Raffeld, Zied Abdullaev, Christine Alewine, Arun Rajan, Giuseppe Giaccone, Ira Pastan, Markku Miettinen, Raffit Hassan

Published Apr 13, 2015 · Vol. 6, No. 13 · pp. 11694-11703

Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma Clinical Research Papers

Emilio Bria, Sara Pilotto, Eliana Amato, Matteo Fassan, Silvia Novello, Umberto Peretti, Tiziana VavalÃ, Stefania Kinspergher, Luisella Righi, Antonio Santo, Matteo Brunelli, Vincenzo Corbo, Eliana Giglioli, Isabella Sperduti, Michele Milella, Marco Chilosi, Aldo Scarpa, Giampaolo Tortora

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 12783-12795

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer Research Paper

Shinn Young Kim, Seung- Hyun Jung, Min Sung Kim, In-Pyo Baek, Sung Hak Lee, Tae-Min Kim, Yeun-Jun Chung, Sug Hyung Lee

Published Mar 26, 2015 · Vol. 6, No. 10 · pp. 7597-7607

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Sujana Movva, Wenhsiang Wen, Wangjuh Chen, Sherri Z. Millis, Zoran Gatalica, Sandeep Reddy, Margaret von Mehren, Brian A. Van Tine

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12234-12247

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Filip Janku, Philipp Angenendt, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Gerald S. Falchook, David S. Hong, Veronica R. Holley, Goran Cabrilo, Jennifer J. Wheler, Sarina A. Piha-Paul, Ralph G. Zinner, Agop Y. Bedikian, Michael J. Overman, Bryan K. Kee, Kevin B. Kim, Scott E. Kopetz, Rajyalakshmi Luthra, Frank Diehl, Funda Meric-Bernstam, Razelle Kurzrock

Published Mar 25, 2015 · Vol. 6, No. 14 · pp. 12809-12821

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis Research Paper

Kei Mitsuhashi, Katsuhiko Nosho, Yasutaka Sukawa, Yasutaka Matsunaga, Miki Ito, Hiroyoshi Kurihara, Shinichi Kanno, Hisayoshi Igarashi, Takafumi Naito, Yasushi Adachi, Mami Tachibana, Tokuma Tanuma, Hiroyuki Maguchi, Toshiya Shinohara, Tadashi Hasegawa, Masafumi Imamura, Yasutoshi Kimura, Koichi Hirata, Reo Maruyama, Hiromu Suzuki, Kohzoh Imai, Hiroyuki Yamamoto, Yasuhisa Shinomura

Published Mar 13, 2015 · Vol. 6, No. 9 · pp. 7209-7220

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver Research Paper

Xiaolei Li, Junyan Tao, Antonio Cigliano, Marcella Sini, Julien Calderaro, Daniel Azoulay, Chunmei Wang, Yan Liu, Lijie Jiang, Katja Evert, Maria I. Demartis, Silvia Ribback, Kirsten Utpatel, Frank Dombrowski, Matthias Evert, Diego F. Calvisi, Xin Chen

Published Mar 12, 2015 · Vol. 6, No. 12 · pp. 10102-10115

Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR Clinical Research Papers

Sang Yun Ha, So-Jung Choi, Jong Ho Cho, Hye Joo Choi, Jinseon Lee, Kyungsoo Jung, Darry Irwin, Xiao Liu, Maruja E. Lira, Mao Mao, Hong Kwan Kim, Yong Soo Choi, Young Mog Shim, Woong Yang Park, Yoon-La Choi, Jhingook Kim

Published Mar 9, 2015 · Vol. 6, No. 7 · pp. 5465-5474

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

Gregory M. Heestand, Razelle Kurzrock

Published Feb 24, 2015 · Vol. 6, No. 7 · pp. 4553-4561

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Andreas Knopf, Justine Lempart, Murat Bas, Julia Slotta-Huspenina, Naglaa Mansour, Marie Kristin Fritsche

Published Jan 30, 2015 · Vol. 6, No. 5 · pp. 3443-3451

Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix Research Paper

Seung-Hyun Jung, Youn Jin Choi, Min Sung Kim, In-Pyo Baek, Sung Hak Lee, Ah Won Lee, Soo Young Hur, Tae-Min Kim, Sug Hyung Lee, Yeun-Jun Chung

Published Jan 23, 2015 · Vol. 6, No. 6 · pp. 4385-4393

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

Libing Xiang, Jiajia Li, Wei Jiang, Xuxia Shen, Wentao Yang, Xiaohua Wu, Huijuan Yang

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4968-4975

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Matthias Scheffler, Marc Bos, Masyar Gardizi, Katharina KÃ¶nig, Sebastian Michels, Jana Fassunke, Carina Heydt, Helen KÃ¼nstlinger, Michaela Ihle, Frank Ueckeroth, Kerstin Albus, Monika Serke, Ulrich Gerigk, Wolfgang Schulte, Karin TÃ¶pelt, Lucia Nogova, Thomas Zander, Walburga Engel-Riedel, Erich Stoelben, Yon-Dschun Ko, Winfried Randerath, Britta Kaminsky, Jens Panse, Carolin Becker, Martin Hellmich, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Reinhard BÃ¼ttner, JÃ¼rgen Wolf

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1315-1326

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

Daniel Martin, Martin C. Abba, Alfredo A. Molinolo, Lynn Vitale-Cross, Zhiyong Wang, Moraima Zaida, Naomi C. Delic, Yardena Samuels, Guy J. Lyons, J. Silvio Gutkind

Published Nov 4, 2014 · Vol. 5, No. 19 · pp. 8906-8923

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Anna Berg, Erling A. Hoivik, Siv MjÃ¸s, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Ã˜yan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, Helga B. Salvesen

Published Nov 4, 2014 · Vol. 6, No. 2 · pp. 1327-1339

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Ming-Mo Hou, Xiaochun Liu, Jennifer Wheler, Aung Naing, David Hong, Robert L. Coleman, Apostolia Tsimberidou, Filip Janku, Ralph Zinner, Karen Lu, Razelle Kurzrock, Siqing Fu

Published Oct 29, 2014 · Vol. 5, No. 22 · pp. 11168-11179

Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Zhong Zheng, Xiangyi He, Chanlu Xie, Sheng Hua, Jianfang Li, Tingfeng Wang, Mu Yao, Soma Vignarajan, Ying Teng, Leila Hejazi, Bingya Liu, Qihan Dong

Published Oct 28, 2014 · Vol. 5, No. 23 · pp. 12304-12316

Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences Research Paper

Mark Kriegsmann, Volker Endris, Thomas Wolf, Nicole Pfarr, Albrecht Stenzinger, Sibylle Loibl, Carsten Denkert, Andreas Schneeweiss, Jan Budczies, Peter Sinn, Wilko Weichert

Published Sep 16, 2014 · Vol. 5, No. 20 · pp. 9952-9965

The structural basis for cancer treatment decisions Review

Ruth Nussinov, Hyunbum Jang, Chung-Jung Tsai

Published Sep 12, 2014 · Vol. 5, No. 17 · pp. 7285-7302

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Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics Research Paper

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma Clinical Research Papers

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer Research Paper

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis Research Paper

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver Research Paper

Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR Clinical Research Papers

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix Research Paper

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences Research Paper

The structural basis for cancer treatment decisions Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics Research Paper

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis Clinical Research Papers

Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma Clinical Research Papers

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer Research Paper

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis Research Paper

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver Research Paper

Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR Clinical Research Papers

Molecular landscape of pancreatic cancer: implications for current clinical trials Review

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix Research Paper

Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies Priority Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience Clinical Research Papers

Targeting cytosolic phospholipase A2 Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences Research Paper

The structural basis for cancer treatment decisions Review

Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper