The Oncosearch | Oncotarget

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma Research Paper

Krittiya Korphaisarn, Van Karlyle Morris, Michael J. Overman, David R. Fogelman, Bryan K. Kee, Kanwal Pratap Singh Raghav, Shanequa Manuel, Imad Shureiqi, Robert A. Wolff, Cathy Eng, David Menter, Stanley R. Hamilton, Scott Kopetz, Arvind Dasari

Published Apr 5, 2017 · Vol. 8, No. 24 · pp. 39268-39279

Genetic alterations in seborrheic keratoses Research Paper

Barbara Heidenreich, Evygenia Denisova, Sivaramakrishna Rachakonda, Onofre Sanmartin, Timo Dereani, Ismail Hosen, Eduardo Nagore, Rajiv Kumar

Published Mar 30, 2017 · Vol. 8, No. 22 · pp. 36639-36649

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Hyo Song Kim, Hanna Lee, Su-Jin Shin, Seung-Hoon Beom, Minkyu Jung, Sujin Bae, Eun Young Lee, Kyu Hyun Park, Yoon Young Choi, Taeil Son, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Woong Sub Koom, Joon Seok Lim, Hyun Cheol Chung, Sung Hoon Noh, Sun Young Rha, Hyunki Kim, Soonmyung Paik

Published Mar 21, 2017 · Vol. 8, No. 24 · pp. 38389-38398

Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes Research Paper

Ji-Yeon Kim, Eunjin Lee, Kyunghee Park, Woong-Yang Park, Hae Hyun Jung, Jin Seok Ahn, Young-Hyuck Im, Yeon Hee Park

Published Mar 3, 2017 · Vol. 8, No. 17 · pp. 27997-28007

PIK3CA mutation and colorectal cancer precision medicine News

Tsuyoshi Hamada, Jonathan A. Nowak, Shuji Ogino

Published Feb 25, 2017 · Vol. 8, No. 14 · pp. 22305-22306

The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes Research Paper

Xiang Li, Ruishan Zhang, Zhuangkai Liu, Shuang Li, Hong Xu

Published Feb 25, 2017 · Vol. 8, No. 12 · pp. 20252-20265

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer Research Paper

Riley A. Hampsch, Kevin Shee, Darcy Bates, Lionel D. Lewis, Laurent DÃ©sirÃ©, Bertrand Leblond, Eugene Demidenko, Kurtis Stefan, Yina H. Huang, Todd W. Miller

Published Feb 21, 2017 · Vol. 8, No. 13 · pp. 21806-21817

Combined MEK and Pi3â€™-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo Research Paper

Oussama ElMokh, DorothÃ©e Ruffieux-DaidiÃ©, Matthias A. Roelli, Amandine Stooss, Wayne A. Phillips, JÃ¼rg Gertsch, Matthias S. Dettmer, Roch-Philippe Charles

Published Feb 21, 2017 · Vol. 8, No. 15 · pp. 24604-24620

Concurrent gene alterations with EGFR mutation and treatment efficacy of EGFR-TKIs in Chinese patients with non-small cell lung cancer Research Paper

Wentao Hu, Yahui Liu, Jian Chen

Published Feb 15, 2017 · Vol. 8, No. 15 · pp. 25046-25054

PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases Research Paper

Etay Ziv, Michael Bergen, Hooman Yarmohammadi, F. Ed Boas, E. Nadia Petre, Constantinos T. Sofocleous, Rona Yaeger, David B. Solit, Stephen B. Solomon, Joseph P. Erinjeri

Published Feb 11, 2017 · Vol. 8, No. 14 · pp. 23529-23538

ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer Research Paper

Anna-Lena GeiÃŸler, Miriam GeiÃŸler, Daniel Kottmann, Lisa Lutz, Christiane D. Fichter, Ralph Fritsch, Britta Weddeling, Frank Makowiec, Martin Werner, Silke Lassmann

Published Feb 9, 2017 · Vol. 8, No. 10 · pp. 17164-17190

Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing Research Paper

Omar Youssef, Aija Knuuttila, PÃ¤ivi PiirilÃ¤, Tom BÃ¶hling, Virinder Sarhadi, Sakari Knuutila

Published Feb 9, 2017 · Vol. 8, No. 11 · pp. 18166-18176

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3 Clinical Research Papers

Cinzia Bersani, Lars Sivars, Linnea Haeggblom, Sebastian DiLorenzo, Michael Mints, Andreas Ã„hrlund-Richter, Nikolaos Tertipis, Eva Munck-Wikland, Anders NÃ¤sman, TorbjÃ¶rn Ramqvist, Tina Dalianis

Published Feb 9, 2017 · Vol. 8, No. 21 · pp. 35339-35350

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience Research Paper

Jun Gong, May Cho, Marvin Sy, Ravi Salgia, Marwan Fakih

Published Feb 2, 2017 · Vol. 8, No. 26 · pp. 42198-42213

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma Review

Yi Cai, Sonam Dodhia, Gloria H. Su

Published Jan 18, 2017 · Vol. 8, No. 13 · pp. 22203-22217

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Cristina Segovia, MÃ³nica MartÃnez-FernÃ¡ndez, Marta DueÃ±as, Carolina Rubio, Fernando F. LÃ³pez-CalderÃ³n, Clotilde Costa, Cristina Saiz-Ladera, MarÃa FernÃ¡ndez-Grajera, JosÃ© Duarte, Huberto GarcÃa MuÃ±oz, Federico de la Rosa, Felipe Villacampa, Daniel Castellano, JesÃºs M. Paramio

Published Jan 2, 2017 · Vol. 8, No. 6 · pp. 10531-10542

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells Research Paper

Hyun-Jung Kim, Soo Yoon Lee, Chan Young Kim, Yun Hwan Kim, Woong Ju, Seung Cheol Kim

Published Dec 27, 2016 · Vol. 8, No. 4 · pp. 6608-6622

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas Research Paper

Sung Hak Lee, Seung Hyun Jung, Tae-Min Kim, Je-Keun Rhee, Hyeon-Chun Park, Min Sung Kim, Sung Soo Kim, Sug Hyung Lee, Chang Hyeok An, Sug Hyung Lee, Yeun-Jun Chung

Published Dec 25, 2016 · Vol. 8, No. 4 · pp. 6579-6588

Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing Research Paper

Feiling Feng, Qingbao Cheng, Liang Yang, Dadong Zhang, Shunlong Ji, Qiangzu Zhang, Yihui Lin, Fugen Li, Lei Xiong, Chen Liu, Xiaoqing Jiang

Published Dec 24, 2016 · Vol. 8, No. 3 · pp. 5349-5360

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper

Hassan Ashktorab, Pooneh Mokarram, Hamed Azimi, Hasti Olumi, Sudhir Varma, Michael L. Nickerson, Hassan Brim

Published Dec 16, 2016 · Vol. 8, No. 5 · pp. 7852-7866

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FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma Research Paper

Genetic alterations in seborrheic keratoses Research Paper

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes Research Paper

PIK3CA mutation and colorectal cancer precision medicine News

The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes Research Paper

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer Research Paper

Combined MEK and Pi3â€™-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo Research Paper

Concurrent gene alterations with EGFR mutation and treatment efficacy of EGFR-TKIs in Chinese patients with non-small cell lung cancer Research Paper

PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases Research Paper

ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer Research Paper

Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing Research Paper

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3 Clinical Research Papers

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience Research Paper

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma Review

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells Research Paper

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas Research Paper

Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing Research Paper

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma Research Paper

Genetic alterations in seborrheic keratoses Research Paper

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer Research Paper

Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes Research Paper

PIK3CA mutation and colorectal cancer precision medicine News

The genetic variants in the PTEN/PI3K/AKT pathway predict susceptibility and CE(A)F chemotherapy response to breast cancer and clinical outcomes Research Paper

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer Research Paper

Combined MEK and Pi3â€™-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo Research Paper

Concurrent gene alterations with EGFR mutation and treatment efficacy of EGFR-TKIs in Chinese patients with non-small cell lung cancer Research Paper

PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases Research Paper

ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer Research Paper

Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing Research Paper

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3 Clinical Research Papers

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience Research Paper

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma Review

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer Research Paper

Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells Research Paper

Whole-exome sequencing identified mutational profiles of high-grade colon adenomas Research Paper

Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing Research Paper

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer Research Paper