The Oncosearch | Oncotarget

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

Maria Sofia Fernandes, Soraia Melo, SÃ©rgia Velho, PatrÃcia Carneiro, FÃ¡tima Carneiro, Raquel Seruca

Published Sep 2, 2016 · Vol. 7, No. 42 · pp. 68546-68558

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways Research Paper

Xin Kong, Fengchao Liu, Jian Gao

Published Sep 1, 2016 · Vol. 7, No. 40 · pp. 66051-66060

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

Fei Ma, Wenjie Zhu, Yanfang Guan, Ling Yang, Xuefeng Xia, Shanshan Chen, Qiao Li, Xiuwen Guan, Zongbi Yi, Haili Qian, Xin Yi, Binghe Xu

Published Sep 1, 2016 · Vol. 7, No. 40 · pp. 66020-66031

DMBA induced mouse mammary tumors display high incidence of activating Pik3ca^H1047 and loss of function Pten mutations Research Paper

MartÃn C. Abba, Yi Zhong, Jaeho Lee, Hyunsuk Kil, Yue Lu, Yoko Takata, Melissa S. Simper, Sally Gaddis, Jianjun Shen, C. Marcelo Aldaz

Published Aug 31, 2016 · Vol. 7, No. 39 · pp. 64289-64299

Gene-gene interactions in gastrointestinal cancer susceptibility Review

Jineun Kim, Seoyun Yum, Changwon Kang, Suk-Jo Kang

Published Aug 30, 2016 · Vol. 7, No. 41 · pp. 67612-67625

Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer Research Paper

Jianchang Qian, Yaqing Chen, Tao Meng, Lanping Ma, Lanfang Meng, Xin Wang, Ting Yu, Arie Zask, Jingkang Shen, Ker Yu

Published Aug 22, 2016 · Vol. 7, No. 41 · pp. 67071-67086

Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm (IPMN) associated with disease progression Research Paper

Sandra Durante, Silvia Vecchiarelli, Annalisa Astolfi, Elisa Grassi, Riccardo Casadei, Donatella Santini, Riccardo Panzacchi, Claudio Ricci, Salvatore Serravalle, Giuseppe Tarantino, Mirella Falconi, Gabriella Teti, Valentina Indio, Andrea Pession, Francesco Minni, Guido Biasco, Mariacristina Di Marco

Published Aug 22, 2016 · Vol. 7, No. 46 · pp. 74797-74806

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Ying Jin, Yang Shao, Xun Shi, Guangyuan Lou, Yiping Zhang, Xue Wu, Xiaoling Tong, Xinmin Yu

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61755-61763

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer Research Paper

Joost H. van Ginkel, Wendy W.J. de Leng, Remco de Bree, Robert J.J. van Es, Stefan M. Willems

Published Aug 11, 2016 · Vol. 7, No. 38 · pp. 61575-61586

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells Research Paper

Wani Arjumand, Cole D. Merry, Chen Wang, Elias Saba, John B. McIntyre, Shujuan Fang, Elizabeth Kornaga, Prafull Ghatage, Corinne M. Doll, Susan P. Lees-Miller

Published Jul 30, 2016 · Vol. 7, No. 50 · pp. 82424-82439

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

Xiaochuan Liu, Aoli Wang, Xiaofei Liang, Juanjuan Liu, Fengming Zou, Cheng Chen, Zheng Zhao, Yuanxin Deng, Hong Wu, Ziping Qi, Beilei Wang, Li Wang, Feiyang Liu, Yunhe Xu, Wenchao Wang, Stacey M. Fernandes, Richard M. Stone, Ilene A. Galinsky, Jennifer R. Brown, Teckpeng Loh, James D. Griffin, Shanchun Zhang, Ellen L. Weisberg, Xin Zhang, Jing Liu, Qingsong Liu

Published Jul 18, 2016 · Vol. 7, No. 33 · pp. 53515-53525

Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation Research Paper

Marina Saisana, S. Michael Griffin, Felicity E.B. May

Published Jul 17, 2016 · Vol. 7, No. 34 · pp. 54445-54462

Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival Research Paper

Kosuke Mima, Jonathan A. Nowak, Zhi Rong Qian, Yin Cao, Mingyang Song, Yohei Masugi, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Tsuyoshi Hamada, Xuehong Zhang, Kana Wu, Jeffrey A. Meyerhardt, Hideo Baba, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino, Reiko Nishihara

Published Jul 4, 2016 · Vol. 7, No. 34 · pp. 55098-55109

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers Research Paper

Rana Hatem, Rania El Botty, Sophie Chateau-Joubert, Jean-Luc Servely, Dalila Labiod, Ludmilla de Plater, Franck Assayag, Florence Coussy, CÃ©line Callens, Sophie Vacher, Fabien Reyal, Sabina Cosulich, VÃ©ronique DiÃ©ras, Ivan BiÃ¨che, Elisabetta Marangoni

Published Jun 21, 2016 · Vol. 7, No. 30 · pp. 48206-48219

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas Research Paper

Marie-Paule Sablin, Coraline Dubot, Jerzy Klijanienko, Sophie Vacher, Lamia Ouafi, Walid Chemlali, Martial Caly, Xavier Sastre-Garau, Emmanuelle Lappartient, Odette Mariani, JosÃ© Rodriguez, Thomas Jouffroy, AngÃ©lique Girod, Valentin Calugaru, Caroline Hoffmann, Rosette Lidereau, FrÃ©dÃ©rique Berger, Maud Kamal, Ivan Bieche, Christophe Le Tourneau

Published Jun 18, 2016 · Vol. 7, No. 30 · pp. 47418-47430

Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1 Research Paper

Qian Zhang, Hai-Bo Yan, Jie Wang, Shu-Jian Cui, Xiao-Qing Wang, Ying-Hua Jiang, Li Feng, Peng-Yuan Yang, Feng Liu

Published Jun 15, 2016 · Vol. 7, No. 29 · pp. 46127-46141

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma Research Paper

Deborah A. Belchis, Li-Hui Tseng, Thomas Gniadek, Lisa Haley, Parvez Lokhandwala, Peter Illei, Christopher D. Gocke, Patrick Forde, Julie Brahmer, Frederic B. Askin, James R. Eshleman, Ming-Tseh Lin

Published Jun 9, 2016 · Vol. 7, No. 29 · pp. 45237-45248

Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance Research Paper

Orsolya MÃ³dos, Henning Reis, Christian Niedworok, Herbert RÃ¼bben, Attila SzendrÃ¶i, Marcell A. SzÃ¡sz, JÃ³zsef TÃmÃ¡r, KornÃ©lia Baghy, Ilona Kovalszky, Tomasz Golabek, Piotr Chlosta, Krzysztof Okon, Benoit Peyronnet, Romain Mathieu, Shahrokh F. Shariat, PÃ©ter HollÃ³si, PÃ©ter NyirÃ¡dy, Tibor Szarvas

Published Jun 5, 2016 · Vol. 7, No. 26 · pp. 39293-39301

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

Maurice P.H.M. Jansen, John W.M. Martens, Jean C.A. Helmijr, Corine M. Beaufort, Ronald van Marion, Niels M.G. Krol, Kim Monkhorst, Anita M.A.C. Trapman- Jansen, Marion E. Meijer-van Gelder, Marjolein J.A. Weerts, Diana E. Ramirez- Ardila, Hendrikus Jan Dubbink, John A. Foekens, Stefan Sleijfer, Els M.J.J. Berns

Published May 30, 2016 · Vol. 7, No. 28 · pp. 43412-43418

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma Research Paper

Breanna M. Javier, Rona Yaeger, Lu Wang, Francisco Sanchez-Vega, Ahmet Zehir, Sumit Middha, Justyna Sadowska, Efsevia Vakiani, Jinru Shia, David Klimstra, Marc Ladanyi, Christine A. Iacobuzio-Donahue, Jaclyn F. Hechtman

Published May 29, 2016 · Vol. 7, No. 32 · pp. 50875-50882

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Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways Research Paper

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

DMBA induced mouse mammary tumors display high incidence of activating Pik3ca^H1047 and loss of function Pten mutations Research Paper

Gene-gene interactions in gastrointestinal cancer susceptibility Review

Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer Research Paper

Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm (IPMN) associated with disease progression Research Paper

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer Research Paper

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells Research Paper

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation Research Paper

Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival Research Paper

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers Research Paper

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas Research Paper

Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1 Research Paper

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma Research Paper

Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance Research Paper

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers Research Paper

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways Research Paper

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy Research Paper

DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations Research Paper

Gene-gene interactions in gastrointestinal cancer susceptibility Review

Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer Research Paper

Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm (IPMN) associated with disease progression Research Paper

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer Research Paper

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells Research Paper

Simultaneous inhibition of Vps34 kinase would enhance PI3KÎ´ inhibitor cytotoxicity in the B-cell malignancies Research Paper

Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation Research Paper

Tumor LINE-1 methylation level and colorectal cancer location in relation to patient survival Research Paper

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers Research Paper

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas Research Paper

Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1 Research Paper

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma Research Paper

Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance Research Paper

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen Research Paper

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma Research Paper

DMBA induced mouse mammary tumors display high incidence of activating Pik3ca^H1047 and loss of function Pten mutations Research Paper