The Oncosearch | Oncotarget

Single cell whole genome sequencing reveals that NFKB1 mutation affects radiotherapy sensitivity in cervical cancer Research Paper

Dong Yang, Weiyuan Zhang, JunQing Liang, Kexin Ma, Peng Chen, Danni Lu, Wenjing Hao

Published Dec 21, 2017 · Vol. 9, No. 7 · pp. 7332-7340

Copy number profiles of paired primary and metastatic colorectal cancers Research Paper

Futoshi Kawamata, Ann-Marie Patch, Katia Nones, Catherine Bond, Diane McKeone, Sally-Ann Pearson, Shigenori Homma, Cheng Liu, Lochlan Fennell, Troy Dumenil, Gunter Hartel, Nozomi Kobayasi, Hideki Yokoo, Moto Fukai, Hiroshi Nishihara, Toshiya Kamiyama, Matthew E. Burge, Christos S. Karapetis, Akinobu Taketomi, Barbara Leggett, Nicola Waddell, Vicki Whitehall

Published Dec 15, 2017 · Vol. 9, No. 3 · pp. 3394-3405

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway Research Paper

Yue-Xing Tu, Shi-Bing Wang, Luo-Qin Fu, Shuang-Shuang Li, Qian-Peng Guo, Yi Wu, Xiao-Zhou Mou, Xiang-Min Tong

Published Dec 14, 2017 · Vol. 9, No. 3 · pp. 3267-3277

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma Research Paper

Wulfran Cacheux, Virginie Dangles-Marie, Etienne Rouleau, Julien Lazartigues, Elodie Girard, Adrien Briaux, Pascale Mariani, Sophie Richon, Sophie Vacher, Bruno Buecher, Marion Richard-Molard, Emmanuelle Jeannot, Nicolas Servant, Fereshteh Farkhondeh, Odette Mariani, Thomas Rio-Frio, Sergio Roman-Roman, Emmanuel Mitry, Ivan Bieche, Astrid LiÃ¨vre

Published Dec 8, 2017 · Vol. 9, No. 1 · pp. 464-476

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Tomotaka Shimura, Yuichiro Tada, Hideaki Hirai, Daisuke Kawakita, Satoshi Kano, Kiyoaki Tsukahara, Akira Shimizu, Soichiro Takase, Yorihisa Imanishi, Hiroyuki Ozawa, Kenji Okami, Yuichiro Sato, Yukiko Sato, Chihiro Fushimi, Hideaki Takahashi, Takuro Okada, Hiroki Sato, Kuninori Otsuka, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Takafumi Togashi, Yushi Ueki, Hisayuki Ota, Mizuo Ando, Shinji Kohsaka, Toyoyuki Hanazawa, Hideaki Chazono, Yoshiyuki Kadokura, Hitome Kobayashi, Toshitaka Nagao

Published Dec 4, 2017 · Vol. 9, No. 2 · pp. 1852-1867

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma Research Paper

Young-Gyu Eun, Dongjin Lee, Young Chan Lee, Bo Hwa Sohn, Eui Hyun Kim, Sun Young Yim, Kee Hwan Kwon, Ju-Seog Lee

Published Nov 27, 2017 · Vol. 8, No. 67 · pp. 111130-111143

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

Doris Helbig, Alexander Quaas, Cornelia Mauch, Sabine Merkelbach-Bruse, Reinhard BÃ¼ttner, Michael Emberger, Marion Wobser, Vanessa RÃ¼sseler, Katharina PÃ¼tz, Elke Binot, Jan Rehker, Jan Budczies, Michaela Angelika Ihle

Published Nov 25, 2017 · Vol. 8, No. 65 · pp. 109457-109467

The macro-evolutionary events in esophageal squamous cell carcinoma Research Paper

Bin Yang, Ting Yan, Heyang Cui, Enwei Xu, Yanchun Ma, Caixia Cheng, Ling Zhang, Pengzhou Kong, Fang Wang, Yu Qian, Jian Yang, Yaoping Li, Hongyi Li, Yanghui Bi, Xiaoling Hu, Juan Wang, Bin Song, Jie Yang, Wei Gao, Jing Liu, Binbin Zou, Ruyi Shi, Yanyan Zhang, Haiyan Liu, Yiqian Liu, Yuanfang Zhai, Lu Chang, Yi Wang, Yingchun Zhang, Zhiwu Jia, Xing Chen, Yanfeng Xi, Guodong Li, Jianfang Liang, Jiansheng Guo, Shiping Guo, Rongsheng Zhang, Xiaolong Cheng, Yongping Cui

Published Nov 15, 2017 · Vol. 8, No. 68 · pp. 112770-112782

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing Research Paper

Masaoki Ito, Yoshihiro Miyata, Shoko Hirano, Shingo Kimura, Fumiko Irisuna, Kyoko Ikeda, Kei Kushitani, Yasuhiro Tsutani, Daisuke Ueda, Norifumi Tsubokawa, Yukio Takeshima, Morihito Okada

Published Nov 14, 2017 · Vol. 8, No. 65 · pp. 108936-108945

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors Research Paper

Meenakshi Mehrotra, Rajesh R. Singh, Sanam Loghavi, Dzifa Yawa Duose, Bedia A. Barkoh, Carmen Behrens, Keyur P. Patel, Mark J. Routbort, Scott Kopetz, Russell R. Broaddus, L. Jeffrey Medeiros, Ignacio I. Wistuba, Rajyalakshmi Luthra

Published Oct 24, 2017 · Vol. 9, No. 12 · pp. 10259-10271

PIK3CA^H1047R-induced paradoxical ERK activation results in resistance to BRAF^V600E specific inhibitors in BRAF^V600E PIK3CA^H1047R double mutant thyroid tumors Research Paper

Matthias A. Roelli, DorothÃ©e Ruffieux-DaidiÃ©, Amandine Stooss, Oussama ElMokh, Wayne A. Phillips, Matthias S. Dettmer, Roch-Philippe Charles

Published Oct 11, 2017 · Vol. 8, No. 61 · pp. 103207-103222

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study Clinical Research Papers

Renwang Liu, Jinghao Liu, Tao Shi, Xiongfei Li, Dian Ren, Gang Chen, Ying Li, Hongyu Liu, Song Xu, Jun Chen

Published Oct 11, 2017 · Vol. 8, No. 59 · pp. 100754-100763

Genes with mutation significance were highly associated with the clinical pattern of patients with breast cancer Research Paper

Wan-Jun Ding, Tao Zeng, Li-Jun Wang, Hong-Bo Lei, Wei Ge, Zhi Wang

Published Oct 3, 2017 · Vol. 8, No. 58 · pp. 98094-98102

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN Research Paper

Jean-FranÃ§ois Laes, Sebastien Sauvage, Gregori Ghitti

Published Sep 28, 2017 · Vol. 8, No. 48 · pp. 84426-84433

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine Research Paper

Helei Hou, Dong Liu, Chuantao Zhang, Yanxia Jiang, Guifang Lu, Na Zhou, Xiaonan Yan, Xiaoping Zhang, Zhuokun Li, Hongmei Zhu, Zhaoyang Qian, Xiaochun Zhang

Published Sep 27, 2017 · Vol. 8, No. 62 · pp. 105072-105080

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers Research Paper

Mohamed E. Salem, Benjamin A. Weinberg, Joanne Xiu, Wafik S. El-Deiry, Jimmy J. Hwang, Zoran Gatalica, Philip A. Philip, Anthony F. Shields, Heinz-Josef Lenz, John L. Marshall

Published Sep 21, 2017 · Vol. 8, No. 49 · pp. 86356-86368

Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells Research Paper

Mancang Gu, Reiko Nishihara, Yang Chen, Wanwan Li, Yan Shi, Yohei Masugi, Tsuyoshi Hamada, Keisuke Kosumi, Li Liu, Annacarolina da Silva, Jonathan A. Nowak, Tyler Twombly, Chunxia Du, Hideo Koh, Wenbin Li, Jeffrey A. Meyerhardt, Brian M. Wolpin, Marios Giannakis, Andrew J. Aguirre, Adam J. Bass, David A. Drew, Andrew T. Chan, Charles S. Fuchs, Zhi Rong Qian, Shuji Ogino

Published Sep 18, 2017 · Vol. 8, No. 50 · pp. 87379-87389

Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer Research Paper

Yoshifumi Shimada, Hitoshi Kameyama, Masayuki Nagahashi, Hiroshi Ichikawa, Yusuke Muneoka, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Masato Nakano, Jun Sakata, Takashi Kobayashi, Hitoshi Nogami, Satoshi Maruyama, Yasumasa Takii, Tetsu Hayashida, Hiromasa Takaishi, Yuko Kitagawa, Eiji Oki, Tsuyoshi Konishi, Fumio Ishida, Shin-ei Kudo, Jennifer E. Ring, Alexei Protopopov, Stephen Lyle, Yiwei Ling, Shujiro Okuda, Takashi Ishikawa, Kohei Akazawa, Kazuaki Takabe, Toshifumi Wakai

Published Aug 24, 2017 · Vol. 8, No. 55 · pp. 93567-93579

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer Research Paper

Pi-Yueh Chang, Jinn-Shiun Chen, Shih-Cheng Chang, Mei-Chia Wang, Nai-Chung Chang, Ying-Hao Wen, Wen-Sy Tsai, Wei-Hsiu Liu, Hsiu-Ling Liu, Jang-Jih Lu

Published Aug 21, 2017 · Vol. 8, No. 42 · pp. 72352-72362

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma Research Paper

Wenli Cui, Mingfu Ma, Shutao Zheng, Zhiping Ma, Liping Su, Wei Zhang

Published Aug 3, 2017 · Vol. 8, No. 39 · pp. 66237-66247

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Single cell whole genome sequencing reveals that NFKB1 mutation affects radiotherapy sensitivity in cervical cancer Research Paper

Copy number profiles of paired primary and metastatic colorectal cancers Research Paper

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway Research Paper

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma Research Paper

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma Research Paper

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

The macro-evolutionary events in esophageal squamous cell carcinoma Research Paper

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing Research Paper

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors Research Paper

PIK3CA^H1047R-induced paradoxical ERK activation results in resistance to BRAF^V600E specific inhibitors in BRAF^V600E PIK3CA^H1047R double mutant thyroid tumors Research Paper

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study Clinical Research Papers

Genes with mutation significance were highly associated with the clinical pattern of patients with breast cancer Research Paper

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN Research Paper

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine Research Paper

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers Research Paper

Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells Research Paper

Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer Research Paper

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer Research Paper

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Single cell whole genome sequencing reveals that NFKB1 mutation affects radiotherapy sensitivity in cervical cancer Research Paper

Copy number profiles of paired primary and metastatic colorectal cancers Research Paper

Ovatodiolide targets chronic myeloid leukemia stem cells by epigenetically upregulating hsa-miR-155, suppressing the BCR-ABL fusion gene and dysregulating the PI3K/AKT/mTOR pathway Research Paper

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma Research Paper

Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas Research Paper

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma Research Paper

Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas Research Paper

The macro-evolutionary events in esophageal squamous cell carcinoma Research Paper

Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing Research Paper

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors Research Paper

PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors Research Paper

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study Clinical Research Papers

Genes with mutation significance were highly associated with the clinical pattern of patients with breast cancer Research Paper

Tumor-biopsy stratification based on mTOR-pathway activity and functional mutations in the upstream genes PIK3CA and PTEN Research Paper

Targeted next generation sequencing in Chinese colorectal cancer patients guided anti-EGFR treatment and facilitated precision cancer medicine Research Paper

Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers Research Paper

Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells Research Paper

Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer Research Paper

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer Research Paper

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma Research Paper

PIK3CA^H1047R-induced paradoxical ERK activation results in resistance to BRAF^V600E specific inhibitors in BRAF^V600E PIK3CA^H1047R double mutant thyroid tumors Research Paper