|
| BRAF vs RAS oncogenes: Are mutations of the same pathway equal Differential signalling and therapeutic implications |
|
https://doi.org/10.18632/oncotarget.2555
Eftychia Oikonomou, Evangelos Koustas, Maria Goulielmaki, and Alexander Pintzas
|
| 11752-11777 |
|
| BclxL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation |
|
https://doi.org/10.18632/oncotarget.2634
Ulrike Keitel, Andreas Scheel, Jürgen Thomale, Rovena Halpape, Silke Kaulfuß, Christina Scheel, and Matthias Dobbelstein
|
| 11778-11791 |
|
| WW domaincontaining oxidoreductase in neuronal injury and neurological diseases |
|
https://doi.org/10.18632/oncotarget.2961
Hsin-Tzu Chang, Chan-Chuan Liu, Shur-Tzu Chen, Ye Vone Yap, Nan-Shang Chang, and Chun-I Sze
|
| 11792-11799 |
|
| ROS production intracellular HSP70 levels and their relationship in human neutrophils: effects of age |
|
https://doi.org/10.18632/oncotarget.2856
Elena I. Kovalenko, Anna A. Boyko, Victor F. Semenkov, Gennady V. Lutsenko, Maria V. Grechikhina, Leonid M. Kanevskiy, Tatyana L. Azhikina, William G. Telford, and Alexander M. Sapozhnikov
|
| 11800-11812 |
|
| A microRNA signature profile in EBV+ diffuse large Bcell lymphoma of the elderly |
|
https://doi.org/10.18632/oncotarget.2952
Tathiana Azevedo de Andrade, Adriane Feijo Evangelista, Antonio Hugo Froes Campos, Wagner Augusto Poles, Natalia Morais Borges, Claudia Malheiros Coutinho Camillo, Fernando Augusto Soares, Jose Vassallo, Roberto Pinto Paes, Maria Claudia Zerbini, Cristovam Scapulatempo, Antonio Correa Alves, Ken H. Young, and Gisele Wally Braga Colleoni
|
| 11813-11826 |
|
| Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stemlike cells |
|
https://doi.org/10.18632/oncotarget.2582
Itay Pickholtz, Shira Saadyan, Gilmor I. Keshet, Victor S. Wang, Rachel Cohen, Peter Bouwman, Jos Jonkers, Stephen W. Byers, Moshe Z. Papa, and Ronit I. Yarden
|
| 11827-11846 |
|
| The antiHER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells |
|
https://doi.org/10.18632/oncotarget.2663
Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, and Kazuhiko Nakagawa
|
| 11847-11856 |
|
| Phospholipase D1 protein coordinates dynamic assembly of HIF1αPHDVHL to regulate HIF1α stability |
|
https://doi.org/10.18632/oncotarget.2613
Mi Hee Park, Kang-Yell Choi, Yunjin Jung, and Do Sik Min
|
| 11857-11872 |
|
| Reduced miR126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGFA |
|
https://doi.org/10.18632/oncotarget.2662
Hongxia Chen, Lingmin Li, Shaojun Wang, Yupeng Lei, Qi Ge, Nonghua Lv, Xiaodong Zhou, and Changyan Chen
|
| 11873-11885 |
|
| Different effects of LDHA inhibition by oxamate in nonsmall cell lung cancer cells |
|
https://doi.org/10.18632/oncotarget.2620
Yang Yang, Dan Su, Lin Zhao, Dan Zhang, Jiaying Xu, Jianmei Wan, Saijun Fan, and Ming Chen
|
| 11886-11896 |
|
| Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has antioxidant and antiapoptotic effects on tumor cells |
|
https://doi.org/10.18632/oncotarget.2472
Giulia Guzzo, Marco Sciacovelli, Paolo Bernardi, and Andrea Rasola
|
| 11897-11908 |
|
| Ret finger proteinlike 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells |
|
https://doi.org/10.18632/oncotarget.2557
Wangbing Chen, Jianjun Lu, Yu Qin, Jingshu Wang, Yun Tian, Dingbo Shi, Shusen Wang, Yao Xiao, Meng Dai, Lu Liu, Guo Wei, Taihua Wu, Bilian Jin, Xiangsheng Xiao, Tie-Bang Kang, Wenlin Huang, and Wuguo Deng
|
| 11909-11923 |
|
| Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53related sarcomas |
|
https://doi.org/10.18632/oncotarget.2650
Lorena Landuzzi, Marianna L. Ianzano, Giordano Nicoletti, Arianna Palladini, Valentina Grosso, Dario Ranieri, Massimiliano Dall’Ora, Elena Raschi, Roberta Laranga, Marco Gambarotti, Piero Picci, Carla De Giovanni, Patrizia Nanni, and Pier-Luigi Lollini
|
| 11924-11938 |
|
| Transcriptomic profiling of taxolresistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response |
|
https://doi.org/10.18632/oncotarget.2654
Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu, and Chuck C.-K. Chao
|
| 11939-11956 |
|
| MBLII141 a chromone derivative enhances irinotecan CPT11 anticancer efficiency in ABCG2positive xenografts |
|
https://doi.org/10.18632/oncotarget.2566
Mylène Honorat, Jérôme Guitton, Charlotte Gauthier, Charlotte Bouard, Florine Lecerf-Schmidt, Basile Peres, Raphaël Terreux, Héloïse Gervot, Catherine Rioufol, Ahcène Boumendjel, Alain Puisieux, Attilio Di Pietro, and Léa Payen
|
| 11957-11970 |
|
| Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo |
|
https://doi.org/10.18632/oncotarget.2647
Xiao-kun Wang, Kenneth Kin Wah To, Li-yan Huang, Jing-hong Xu, Ke Yang, Fang Wang, Zhen-cong Huang, Sheng Ye, and Li-wu Fu
|
| 11971-11985 |
|
| NEK2 mediates ALDH1A1dependent drug resistance in multiple myeloma |
|
https://doi.org/10.18632/oncotarget.2388
Ye Yang, Wen Zhou, Jiliang Xia, Zhimin Gu, Erik Wendlandt, Xin Zhan, Siegfried Janz, Guido Tricot, and Fenghuang Zhan
|
| 11986-11997 |
|
| The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases |
|
https://doi.org/10.18632/oncotarget.2426
Jie Shen, Juan Lu, Liyuan Sui, Dan Wang, Meizhen Yin, Inka Hoffmann, Anne Legler, and Gert O. Pflugfelder
|
| 11998-12015 |
|
| Role of p53 in the progression of gastric cancer |
|
https://doi.org/10.18632/oncotarget.2434
Rita A. Busuttil, Giada V. Zapparoli, Sue Haupt, Christina Fennell, Stephen Q. Wong, Jia-Min B. Pang, Elena A. Takeno, Catherine Mitchell, Natasha Di Costanzo, Stephen Fox, Ygal Haupt, Alexander Dobrovic, and Alex Boussioutas
|
| 12016-12026 |
|
| Melanomainitiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation |
|
https://doi.org/10.18632/oncotarget.2482
Muly Tham, Kar Wai Tan, Jo Keeble, Xiaojie Wang, Sandra Hubert, Luke Barron, Nguan Soon Tan, Masashi Kato, Armelle Prevost-Blondel, Veronique Angeli, and Jean-Pierre Abastado
|
| 12027-12042 |
|
| PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells |
|
https://doi.org/10.18632/oncotarget.2658
Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg Schäfer, Stephan Geley, Isabel Heidegger, Helmut Klocker, and Zoran Culig
|
| 12043-12056 |
|
| AGK enhances angiogenesis and inhibits apoptosis via activation of the NFκB signaling pathway in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2666
Yanmei Cui, Chuyong Lin, Zhiqiang Wu, Aibin Liu, Xin Zhang, Jinrong Zhu, Geyan Wu, Jueheng Wu, Mengfeng Li, Jun Li, and Libing Song
|
| 12057-12069 |
|
| Acidosis promotes invasiveness of breast cancer cells through ROSAKTNFκB pathway |
|
https://doi.org/10.18632/oncotarget.2514
Subash C. Gupta, Ramesh Singh, Radhika Pochampally, Kounosuke Watabe, and Yin-Yuan Mo
|
| 12070-12082 |
|
| MicroRNA638 inhibits cell proliferation invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma |
|
https://doi.org/10.18632/oncotarget.2499
Jiwei Zhang, Bojian Fei, Qifeng Wang, Mingxu Song, Yuan Yin, Binbin Zhang, Shujuan Ni, Weijie Guo, Zehua Bian, Chao Quan, Zhihui Liu, Yugang Wang, Jian Yu, Xiang Du, Dong Hua, and Zhaohui Huang
|
| 12083-12096 |
|
| Eselectin ligand1 controls circulating prostate cancer cell rolling/adhesion and metastasis |
|
https://doi.org/10.18632/oncotarget.2503
Sayeda Yasmin-Karim, Michael R. King, Edward M. Messing, and Yi-Fen Lee
|
| 12097-12110 |
|
| Cooperative interactions between p53 and NFκB enhance cell plasticity |
|
https://doi.org/10.18632/oncotarget.2545
Alessandra Bisio, Judit Zámborszky, Sara Zaccara, Mattia Lion, Toma Tebaldi, Vasundhara Sharma, Ivan Raimondi, Federica Alessandrini, Yari Ciribilli, and Alberto Inga
|
| 12111-12125 |
|
| The cylindromatosis gene product CYLD interacts with MIB2 to regulate notch signalling |
|
https://doi.org/10.18632/oncotarget.2573
Neil Rajan, Richard J.R. Elliott, Alice Smith, Naomi Sinclair, Sally Swift, Christopher J. Lord, and Alan Ashworth
|
| 12126-12140 |
|
| MiR520d5p directly targets TWIST1 and downregulates the metastamiR miR10b |
|
https://doi.org/10.18632/oncotarget.2559
Pinchas Tsukerman, Rachel Yamin, Einat Seidel, Saleh Khawaled, Dominik Schmiedel, Tomer Bar-Mag, and Ofer Mandelboim
|
| 12141-12150 |
|
| GLI inhibitor GANT61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKTmTOR axis |
|
https://doi.org/10.18632/oncotarget.2569
Ritesh K. Srivastava, Samer Zaid Kaylani, Nayf Edrees, Changzhao Li, Sarang S. Talwelkar, Jianmin Xu, Komaraiah Palle, Joseph G. Pressey, and Mohammad Athar
|
| 12151-12165 |
|
| Molecular profiling and computational network analysis of TAZmediated mammary tumorigenesis identifies actionable therapeutic targets |
|
https://doi.org/10.18632/oncotarget.2570
Costa Frangou, Ying-Wei Li, He Shen, Nuo Yang, Kayla E. Wilson, Maxime Blijlevens, Jin Guo, Norma J. Nowak, and Jianmin Zhang
|
| 12166-12176 |
|
| Downregulation of microRNA100 enhances the ICMTRac1 signaling and promotes metastasis of hepatocellular carcinoma cells |
|
https://doi.org/10.18632/oncotarget.2601
Hui-Chao Zhou, Jian-Hong Fang, Xu Luo, Lei Zhang, Jine Yang, Chong Zhang, and Shi-Mei Zhuang
|
| 12177-12188 |
|
| EBVdriven LMP1 and IFNγ upregulate PDL1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy |
|
https://doi.org/10.18632/oncotarget.2608
Wenfeng Fang, Jianwei Zhang, Shaodong Hong, Jianhua Zhan, Nan Chen, Tao Qin, Yanna Tang, Yaxiong Zhang, Shiyang Kang, Ting Zhou, Xuan Wu, Wenhua Liang, Zhihuang Hu, Yuxiang Ma, Yuanyuan Zhao, Ying Tian, Yunpeng Yang, Cong Xue, Yue Yan, Xue Hou, Peiyu Huang, Yan Huang, Hongyun Zhao, and Li Zhang
|
| 12189-12202 |
|
| CD151α3β1 integrin complexes suppress ovarian tumor growth by repressing slugmediated EMT and canonical Wnt signaling |
|
https://doi.org/10.18632/oncotarget.2622
Lauren A. Baldwin, John T. Hoff, Jason Lefringhouse, Michael Zhang, Changhe Jia, Zeyi Liu, Sonia Erfani, Hongyan Jin, Mei Xu, Qing-Bai She, John R. van Nagell, Chi Wang, Li Chen, Rina Plattner, David M. Kaetzel, Jia Luo, Michael Lu, Dava West, Chunming Liu, Fred R. Ueland, Ronny Drapkin, Binhua P. Zhou, and Xiuwei H. Yang
|
| 12203-12217 |
|
| A recessive variant of XRCC4 predisposes to non BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization |
|
https://doi.org/10.18632/oncotarget.2623
Min He, Xin Hu, Li Chen, A-Yong Cao, Ke-Da Yu, Ting-Yan Shi, Xia-Ying Kuang, Wen-Biao Shi, Hong Ling, Shan Li, Feng Qiao, Ling Yao, Qingyi Wei, Gen-Hong Di, and Zhi-Ming Shao
|
| 12218-12232 |
|
| Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein HBx in HBVrelated advanced hepatocellular carcinomas |
|
https://doi.org/10.18632/oncotarget.2625
Mi-Young Cho, Jae Youn Cheong, Wonchung Lim, Sujin Jo, Youngsoo Lee, Hee-Jung Wang, Kyou-Hoon Han, and Hyeseong Cho
|
| 12233-12246 |
|
| GALNT2 suppresses malignant phenotypes through IGF1 receptor and predicts favorable prognosis in neuroblastoma |
|
https://doi.org/10.18632/oncotarget.2627
Wan-Ling Ho, Chih-Hsing Chou, Yung-Ming Jeng, Meng-Yao Lu, Yung-Li Yang, Shiann-Tarng Jou, Dong-Tsamn Lin, Hsiu-Hao Chang, Kai-Hsin Lin, Wen-Ming Hsu, and Min-Chuan Huang
|
| 12247-12259 |
|
| ZNF282 Zinc finger protein 282 a novel E2F1 coactivator promotes esophageal squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.2630
So-Young Yeo, Sang Yun Ha, Eun Ji Yu, Keun-Woo Lee, Jeong Hoon Kim, and Seok-Hyung Kim
|
| 12260-12272 |
|
| Wnt5A regulates ABCB1 expression in multidrugresistant cancer cells through activation of the noncanonical PKA/βcatenin pathway |
|
https://doi.org/10.18632/oncotarget.2631
Tsai-Hsien Hung, Sheng-Chi Hsu, Ching-Yi Cheng, Kong-Bung Choo, Ching-Ping Tseng, Tse-Ching Chen, Ying-Wei Lan, Tsung-Teng Huang, Hsin-Chih Lai, Chuan-Mu Chen, and Kowit-Yu Chong
|
| 12273-12290 |
|
| MiR373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer |
|
https://doi.org/10.18632/oncotarget.2577
Yue Zhang, Fu-Jun Zhao, Li-Lan Chen, Luo-Qiao Wang, Kenneth P. Nephew, Ying-Li Wu, and Shu Zhang
|
| 12291-12303 |
|
| Targeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B AKT and cell proliferation |
|
https://doi.org/10.18632/oncotarget.2639
Zhong Zheng, Xiangyi He, Chanlu Xie, Sheng Hua, Jianfang Li, Tingfeng Wang, Mu Yao, Soma Vignarajan, Ying Teng, Leila Hejazi, Bingya Liu, and Qihan Dong
|
| 12304-12316 |
|
| The novel IκB kinase β inhibitor IMD0560 prevents bone invasion by oral squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.2640
Yukiyo Tada, Shoichiro Kokabu, Goro Sugiyama, Chihiro Nakatomi, Kazuhiro Aoki, Hidefumi Fukushima, Kenji Osawa, Yasutaka Sugamori, Keiichi Ohya, Masato Okamoto, Tomoyuki Fujikawa, Akiko Itai, Kou Matsuo, Seiji Watanabe, and Eijiro Jimi
|
| 12317-12330 |
|
| Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloidderived suppressor cells |
|
https://doi.org/10.18632/oncotarget.2589
Bo-Ra Lee, Sun-Young Chang, Eun-Hye Hong, Bo-Eun Kwon, Hong Min Kim, Yeon-Jeong Kim, Jongkook Lee, Hyun-Jong Cho, Jae-Hee Cheon, and Hyun-Jeong Ko
|
| 12331-12345 |
|
| Efficacy of tumortargeting Salmonella typhimurium A1R in combination with antiangiogenesis therapy on a pancreatic cancer patientderived orthotopic xenograft PDOX and cell line mouse models |
|
https://doi.org/10.18632/oncotarget.2641
Yukihiko Hiroshima, Yong Zhang, Takashi Murakami, Ali Maawy, Shinji Miwa, Mako Yamamoto, Shuya Yano, Sho Sato, Masashi Momiyama, Ryutaro Mori, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Yasushi Ichikawa, Michael Bouvet, Itaru Endo, Ming Zhao, and Robert M. Hoffman
|
| 12346-12357 |
|
| Bortezomib induces AMPKdependent autophagosome formation uncoupled from apoptosis in drug resistant cells |
|
https://doi.org/10.18632/oncotarget.2590
Sajjeev Jaganathan, Ehsan Malek, Subrahmanya Vallabhapurapu, Sivakumar Vallabhapurapu, and James J. Driscoll
|
| 12358-12370 |
|
| Preclinical efficacy of maternal embryonic leucinezipper kinase MELK inhibition in acute myeloid leukemia |
|
https://doi.org/10.18632/oncotarget.2642
Houda Alachkar, Martin B.G. Mutonga, Klaus H. Metzeler, Noreen Fulton, Gregory Malnassy, Tobias Herold, Karsten Spiekermann, Stefan K. Bohlander, Wolfgang Hiddemann, Yo Matsuo, Wendy Stock, and Yusuke Nakamura
|
| 12371-12382 |
|
| Expansion of CTCs from early stage lung cancer patients using a microfluidic coculture model |
|
https://doi.org/10.18632/oncotarget.2592
Zhuo Zhang, Hiroe Shiratsuchi, Jules Lin, Guoan Chen, Rishindra M. Reddy, Ebrahim Azizi, Shamileh Fouladdel, Andrew C. Chang, Lin Lin, Hui Jiang, Meghna Waghray, Gary Luker, Diane M. Simeone, Max S. Wicha, David G. Beer, Nithya Ramnath, and Sunitha Nagrath
|
| 12383-12397 |
|
| Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues |
|
https://doi.org/10.18632/oncotarget.2643
Rongwei Sun, Xudong Wang, Huijun Zhu, Haijun Mei, Wei Wang, Shu Zhang, and Jianfei Huang
|
| 12398-12409 |
|
| Tamoxifen represses alcoholinduced transcription of RNA polymerase IIIdependent genes in breast cancer cells |
|
https://doi.org/10.18632/oncotarget.2678
Qian Zhong, Ganggang Shi, Qingsong Zhang, Lei Lu, Daniel Levy, and Shuping Zhong
|
| 12410-12417 |
|
| Therapeutic vaccination against fibronectin EDA attenuates progression of metastatic breast cancer |
|
https://doi.org/10.18632/oncotarget.2628
Julia Femel, Elisabeth J.M. Huijbers, Falk Saupe, Jessica Cedervall, Lei Zhang, Pernilla Roswall, Erik Larsson, Helena Olofsson, Kristian Pietras, Anna Dimberg, Lars Hellman, and Anna-Karin Olsson
|
| 12418-12427 |
|
| TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR |
|
https://doi.org/10.18632/oncotarget.2660
Kun Wang, Tiantian Liu, Nan Ge, Li Liu, Xiaotian Yuan, Jikai Liu, Feng Kong, Chang Wang, Hongbo Ren, Keqiang Yan, Sanyuan Hu, Zhonghua Xu, Magnus Björkholm, Yidong Fan, Shengtian Zhao, Cheng Liu, and Dawei Xu
|
| 12428-12439 |
|
| Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases |
|
https://doi.org/10.18632/oncotarget.2574
Zoran Gatalica, Sherri Z. Millis, Semir Vranic, Ryan Bender, Gargi D. Basu, Andreas Voss, and Daniel D. Von Hoff
|
| 12440-12447 |
|
| Early outcome prediction on 18Ffluorocholine PET/CT in metastatic castrationresistant prostate cancer patients treated with abiraterone |
|
https://doi.org/10.18632/oncotarget.2558
Ugo De Giorgi, Paola Caroli, Salvatore L. Burgio, Cecilia Menna, Vincenza Conteduca, Emanuela Bianchi, Francesca Fabbri, Elisa Carretta, Dino Amadori, Giovanni Paganelli, and Federica Matteucci
|
| 12448-12458 |
|
| Increased number of negative lymph nodes is associated with improved cancer specific survival in pathological IIIB and IIIC rectal cancer treated with preoperative radiotherapy |
|
https://doi.org/10.18632/oncotarget.2560
Qingguo Li, Changhua Zhuo, Guoxiang Cai, Dawei Li, Lei Liang, and Sanjun Cai
|
| 12459-12471 |
