Vol 5, No 17

mTORC2 takes the longevity stAGE

TWIST and ovarian cancer stem cells: implications for chemoresistance and metastasis

Altered Mucins (MUC) Trafficking in Benign and Malignant Conditions

The structural basis for cancer treatment decisions

AP4 is required for mitogen- and c-MYC-induced cell cycle progression

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas

Clinical outcomes of a novel combination of lenalidomide and rituximab followed by stem cell transplantation for relapsed/refractory aggressive B-cell non-hodgkin lymphoma

¹⁸ FDG-PET/CT for prognostic stratification of patients with multiple myeloma relapse after stem cell transplantation

Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma

Applicability of the methylated CpG sites of paired box 5 (PAX5) promoter for prediction the prognosis of gastric cancer

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk

TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma

High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression

Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo

EMT and EGFR in CTCs cytokeratin negative non-metastatic breast cancer

Aurora kinase a suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells

Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair

Beclin-1-independent autophagy positively regulates internal ribosomal entry site-dependent translation of hypoxia-inducible factor 1α under nutrient deprivation

Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells

Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells

Osteoblast-derived WISP-1 increases VCAM-1 expression and enhances prostate cancer metastasis by down-regulating miR-126

MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer

Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma

N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation

Selective targeting of KRAS-Mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-Mutant cells

MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape

CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma

A central role for TRPS1 in the control of cell cycle and cancer development

Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

Expression and functions of galectin-7 in ovarian cancer

Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense

Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment

The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer

Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494

Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner

The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma

Neddylation pathway is up-regulated in human intrahepatic cholangiocarcinoma and serves as a potential therapeutic target

Co-ordination of cell cycle, migration and stem cell-like activity in breast cancer

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice

­Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer

Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics

miR-200c overexpression is associated with better efficacy of EGFR-TKIs in non-small cell lung cancer patients with EGFR wild-type

Estrogen Receptor Alpha Prevents Bladder Cancer Development via INPP4B inhibited Akt Pathway in vitro and in vivo

Mutant NRAS^Q61 shares signaling similarities across various cancer types – potential implications for future therapies

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity