The Oncosearch | Oncotarget

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Athira Narayan, Yu Yan, Ala Lisok, Mary Brummet, Martin G. Pomper, Wojciech G. Lesniak, Robert F. Dannals, Vanessa F. Merino, Babak Behnam Azad

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5731-5744

Keywords: FDOPA, PET, neuroendocrine tumors, Fluorine-18, molecular imaging

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Nathan D. Seligson, Colin W. Stets, Bryce W. Demoret, Achal Awasthi, Nicholas Grosenbacher, Reena Shakya, John L. Hays, James L. Chen

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5671-5679

Keywords: dedifferentiated liposarcomas, MDM2, HDAC2, romidepsin, MI-192

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Jui-Wen Ma, Chao-Ming Hung, Ying-Chao Lin, Chi-Tang Ho, Jung-Yie Kao, Tzong-Der Way

Published Sep 26, 2019 · Vol. 10, No. 55 · pp. 5727-5729

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Balaji Krishnamachary, Dharmalingam Subramaniam, Prasad Dandawate, Sivapriya Ponnurangam, Pugazhendhi Srinivasan, Prabhu Ramamoorthy, Shahid Umar, Sufi Mary Thomas, Animesh Dhar, Seth Septer, Scott J. Weir, Thomas Attard, Shrikant Anant

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5576-5591

Keywords: Wnt signaling, beta-catenin, natural product, tumor xenograft, preventive agent

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

Hidehiko Hishikawa, Masaki Kaibori, Takumi Tsuda, Kosuke Matsui, Tadayoshi Okumura, Eiichi Ozeki, Kengo Yoshii

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5622-5631

Keywords: near infrared fluorescence imaging, photodynamic therapy, indocyanine green, lactosome, gall bladder cancer

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Jamie M. Aye, Laura L. Stafman, Adele P. Williams, Evan F. Garner, Jerry E. Stewart, Joshua C. Anderson, Smitha Mruthyunjayappa, Mary G. Waldrop, Caroline D. Goolsby, Hooper R. Markert, Colin Quinn, Raoud Marayati, Elizabeth Mroczek-Musulman, Christopher D. Willey, Karina J. Yoon, Kimberly F. Whelan, Elizabeth A. Beierle

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5534-5548

Keywords: kinase inhibition, Wilms tumor

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

Caitlin D. Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V. Perez, Jennifer Stephens, Bronislaw Pytowski, Heather Wasserstrom, Louis F. Stancato, Beverly Falcon

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5523-5533

Keywords: angiogenesis, pediatric cancer, VEGFR2, ramucirumab, DC101

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

Fan Yang, Wenwu Xiao, Yanlei Liu, Ruiwu Liu, Randall Kramer, Xiaocen Li, Yousif Ajena, Christopher M. Baehr, Tatu Rojalin, Hongyong Zhang, Kit S. Lam

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5468-5479

Keywords: oral squamous cancer, α3 integrin, optical imaging, cancer-targeting peptide, orthotopic xenograft model

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Michelle M. Williams, David L. Elion, Bushra Rahman, Donna J. Hicks, Violeta Sanchez, Rebecca S. Cook

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5389-5402

Keywords: Mcl-1, ABT-263 resistance, mTORC1 signaling, luminal breast cancers

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Jennifer Bourn, Sony Pandey, Jashim Uddin, Lawrence Marnett, Maria Cekanova

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5168-5180

Keywords: bladder cancer, TKIs, RTKIs, COX-2, targeted therapies

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Jennifer Bryant, Nikolaos Batis, Anna Clara Franke, Gabriella Clancey, Margaret Hartley, Gordon Ryan, Jill Brooks, Andrew D. Southam, Nicholas Barnes, Joanna Parish, Sally Roberts, Farhat Khanim, Rachel Spruce, Hisham Mehanna

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5229-5244

Keywords: head and neck cancer, drug repurposing, drug repositioning, quinacrine, mepacrine

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

Jingbo Qiao, Eric J. Rellinger, Kwang Woon Kim, Camille M. Powers, Sora Lee, Hernan Correa, Dai H. Chung

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5028-5040

Keywords: neuroblastoma, tumor suppressor, CTNNA2 (α-N-catenin), NF-κB

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Nicci Owusu-Brackett, Kurt W. Evans, Argun Akcakanat, Erkan Yuca, Coya Tapia, Yasmeen Qamar Rizvi, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5011-5019

Keywords: breast cancer, TAK228, PI3K, PTEN, TNBC

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Simon Durand, Cécile Pierre-Eugène, Olivier Mirabeau, Caroline Louis-Brennetot, Valérie Combaret, Léo Colmet-Daage, Orphée Blanchard, Angela Bellini, Estelle Daudigeos-Dubus, Virginie Raynal, Gudrun Schleiermacher, Sylvain Baulande, Olivier Delattre, Isabelle Janoueix-Lerosey

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4937-4950

Keywords: neuroblastoma, ALK mutations, heterogeneity, clonal evolution, ALK inhibitors

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Manabu Sasada, Takuya Iyoda, Tatsufumi Asayama, Yusuke Suenaga, Shunsuke Sakai, Naoya Kase, Hiroaki Kodama, Sana Yokoi, Yoichiro Isohama, Fumio Fukai

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4960-4972

Keywords: integrin, Myc, proteasomal degradation, fibronectin, neuroblastoma

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Omkara Lakshmi Veeranki, Zhimin Tong, Rashmi Dokey, Alicia Mejia, Jianhu Zhang, Yawei Qiao, Pankaj Kumar Singh, Riham Katkhuda, Barbara Mino, Ramesh Tailor, Jaime Rodriguez Canales, Roland Bassett, Jaffer Ajani, Ji Yuan Wu, Scott Kopetz, Mariela Blum, Wayne Hofstetter, Michael Tetzlaff, Sunil Krishnan, Steven H. Lin, Dipen Maru

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4703-4718

Keywords: CDK 9 Inhibitor, esophageal adenocarcinoma, radiation, Axl

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Daniel Bug, Friedrich Feuerhake, Eva Oswald, Julia Schüler, Dorit Merhof

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4587-4597

Keywords: deep learning, digital pathology, histology, non small cell lung cancer, xenograft

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Feng-Mao Lin, Susan E. Yost, Wei Wen, Paul H. Frankel, Daniel Schmolze, Pei-Guo Chu, Yate-Ching Yuan, Zheng Liu, John Yim, Zhen Chen, Yuan Yuan

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4356-4368

Keywords: AKT, differential expression, AKT targeting, TNBC

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

Elgilda Musi, Gary K. Schwartz, Jae Hyuk Yoo, Shannon J. Odelberg, Dean Y. Li, Michael Y. Bonner, Ponniah Selvakumar, Shikha Rao, Linda C. Gilbert, Justin Elsey, Jack L. Arbiser

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4424-4436

Keywords: melanoma, chemotherapy

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A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A side-by-side evaluation of [18F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Correction: Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells Correction

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosomes has antineoplastic effects for gallbladder cancer Research Paper

The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor Research Paper

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy Research Paper

One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer Research Paper

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma Research Paper

Semi-automated analysis of digital whole slides from humanized lung-cancer xenograft models for checkpoint inhibitor response prediction Research Paper

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo Research Paper

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper