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AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Marie-Anne Goyette, Rebecca Cusseddu, Islam Elkholi, Afnan Abu-Thuraia, Nehme El-Hachem, Benjamin Haibe-Kains, Jean-Philippe Gratton, Jean-François Côté

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2055-2067

Keywords: triple-negative breast cancer, drug repurposing, AXL, phenothiazines, metastasis

Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models Research Paper

Katsumi Kozasa, Seiji Mabuchi, Yuri Matsumoto, Hiromasa Kuroda, Eriko Yokoi, Naoko Komura, Mahiru Kawano, Ryoko Takahashi, Tomoyuki Sasano, Kotaro Shimura, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Kazunori Nagasaka, Tadashi Kimura

Published Mar 8, 2019 · Vol. 10, No. 20 · pp. 1887-1902

An oncolytic adenovirus 11p vector expressing adenovirus death protein in the E1 region showed significant apoptosis and tumour-killing ability in metastatic prostate cells Research Paper

Haidong Wu, Ya-Fang Mei

Published Mar 8, 2019 · Vol. 10, No. 20 · pp. 1957-1974

A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Research Paper

Alice Gerges Geagea, Manfredi Rizzo, Abdo Jurjus, Francesco Cappello, Angelo Leone, Giovanni Tomasello, CÃ©line Gracia, Sahar Al Kattar, Liliane Massaad-Massade, Assaad Eid

Published Feb 12, 2019 · Vol. 10, No. 13 · pp. 1284-1305

Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer Research Paper

Ramona Graves-Deal, Galina Bogatcheva, Saba Rehman, Yuanyuan Lu, James N. Higginbotham, Bhuminder Singh

Published Feb 12, 2019 · Vol. 10, No. 13 · pp. 1320-1333

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft Research Paper

Siddesh V. Hartimath, Ayman El-Sayed, Amal Makhlouf, Wendy Bernhard, Carolina Gonzalez, Wayne Hill, Angel Casaco Parada, Kris Barreto, Clarence Ronald Geyer, Humphrey Fonge

Published Feb 1, 2019 · Vol. 10, No. 10 · pp. 1031-1044

Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells Research Paper

Austin R. Dosch, Xizi Dai, Alexander A. Gaidarski III, Chanjuan Shi, Jason A. Castellanos, Michael N. VanSaun, Nipun B. Merchant, Nagaraj S. Nagathihalli

Published Feb 1, 2019 · Vol. 10, No. 10 · pp. 1056-1069

Andrographolide induces DNA damage in prostate cancer cells Research Paper

Ingrid S. Forestier-RomÃ¡n, AndrÃ©s LÃ³pez-Rivas, MarÃa M. SÃ¡nchez-VÃ¡zquez, Krizia Rohena-Rivera, Gretchen Nieves-Burgos, Humberto Ortiz-Zuazaga, Carlos A. Torres-Ramos, Magaly MartÃnez-Ferrer

Published Feb 1, 2019 · Vol. 10, No. 10 · pp. 1085-1101

Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles Research Paper

Harold W. Davis, Subrahmanya D. Vallabhapurapu, Zhengtao Chu, Swarajya L. Vallabhapurapu, Robert S. Franco, Michelle Mierzwa, William Kassing, William L. Barrett, Xiaoyang Qi

Published Jan 25, 2019 · Vol. 10, No. 8 · pp. 856-868

Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy Research Paper

Tomoki Yamano, Shuji Kubo, Aya Yano, Tomoko Kominato, Shino Tanaka, Masataka Ikeda, Naohiro Tomita

Published Jan 8, 2019 · Vol. 10, No. 3 · pp. 352-367

Implication of calcium activated RasGRF2 in Annexin A6-mediated breast tumor cell growth and motility Research Paper

Diva S. Whalen, Sarrah E. Widatalla, Olga Y. Korolkova, Gladys S. Nangami, Heather K. Beasley, Stephen D. Williams, Carlos Virgous, Brian D. Lehmann, Josiah Ochieng, Amos M. Sakwe

Published Jan 4, 2019 · Vol. 10, No. 2 · pp. 133-151

piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo Research Paper

Daniel I. Jacobs, Qin Qin, Alan Fu, Zeming Chen, Jiangbing Zhou, Yong Zhu

Published Dec 28, 2018 · Vol. 9, No. 102 · pp. 37616-37626

Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001 Research Paper

Cristina L. Abrahams, Xiaofan Li, Millicent Embry, Abigail Yu, Stellanie Krimm, Sarah Krueger, Nancy Y. Greenland, Kwun Wah Wen, Chris Jones, Venita DeAlmeida, Willy A. Solis, Shannon Matheny, Toni Kline, Alice Y. Yam, Ryan Stafford, Arun P. Wiita, Trevor Hallam, Mark Lupher, Arturo Molina

Published Dec 28, 2018 · Vol. 9, No. 102 · pp. 37700-37714

TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas Research Paper

Giovanna Casili, Maria Caffo, Michela Campolo, Valeria Barresi, Gerardo Caruso, Salvatore M. Cardali, Marika Lanza, Raffaella Mallamace, Alessia Filippone, Alfredo Conti, Antonino GermanÃ², Salvatore Cuzzocrea, Emanuela Esposito

Published Dec 25, 2018 · Vol. 9, No. 101 · pp. 37564-37580

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

Jayati Chakrabarti, Loryn Holokai, LiJyun Syu, Nina G. Steele, Julie Chang, Jiang Wang, Syed Ahmed, Andrzej Dlugosz, Yana Zavros

Published Dec 21, 2018 · Vol. 9, No. 100 · pp. 37439-37457

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Jonathan C. DeLong, Siamak Amirfakhri, Filemoni Filemoni, Sang Nam Yoon, Paul J. Yazaki, John E. Shivley, Brian Datnow, Bryan M. Clary, Robert M. Hoffman, Michael Bouvet

Published Dec 18, 2018 · Vol. 9, No. 99 · pp. 37333-37342

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

Abdul Khalid Siraj, Poyil Pratheeshkumar, Sandeep Kumar Parvathareddy, Sasidharan Padmaja Divya, Fouad Al-Dayel, Asma Tulbah, Dahish Ajarim, Khawla S. Al-Kuraya

Published Dec 18, 2018 · Vol. 9, No. 99 · pp. 37319-37332

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models Research Paper

Kaiming Sun, Keith Mikule, Zebin Wang, Grace Poon, Aparajitha Vaidyanathan, Gillian Smith, Zhi-Yi Zhang, Jeffrey Hanke, Sridhar Ramaswamy, Jing Wang

Published Dec 14, 2018 · Vol. 9, No. 98 · pp. 37080-37096

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

James L. Figarola, Jyotsana Singhal, Sharad Singhal, Jyotirmoy Kusari, Arthur Riggs

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 36945-36965

TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase Research Paper

Elena Brin, Katherine Wu, Eleanor Dagostino, Mario Meng-Chiang Kuo, Yudou He, Wei-Jong Shia, Li-Chang Chen, Mariusz Stempniak, Richard Hickey, Robert Almassy, Richard Showalter, James Thomson

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 36914-36928

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AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models Research Paper

An oncolytic adenovirus 11p vector expressing adenovirus death protein in the E1 region showed significant apoptosis and tumour-killing ability in metastatic prostate cells Research Paper

A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Research Paper

Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer Research Paper

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft Research Paper

Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells Research Paper

Andrographolide induces DNA damage in prostate cancer cells Research Paper

Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles Research Paper

Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy Research Paper

Implication of calcium activated RasGRF2 in Annexin A6-mediated breast tumor cell growth and motility Research Paper

piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo Research Paper

Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001 Research Paper

TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas Research Paper

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models Research Paper

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models Research Paper

An oncolytic adenovirus 11p vector expressing adenovirus death protein in the E1 region showed significant apoptosis and tumour-killing ability in metastatic prostate cells Research Paper

A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Research Paper

Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer Research Paper

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft Research Paper

Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells Research Paper

Andrographolide induces DNA damage in prostate cancer cells Research Paper

Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles Research Paper

Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy Research Paper

Implication of calcium activated RasGRF2 in Annexin A6-mediated breast tumor cell growth and motility Research Paper

piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo Research Paper

Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001 Research Paper

TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas Research Paper

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer Research Paper

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment Research Paper

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models Research Paper

Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas Research Paper

TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase Research Paper