The Oncosearch | Oncotarget

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Louie Semaan, Qingning Zeng, Yong Lu, Yi Zhang, Mehdi Mohamad Zreik, Mohamad Baqer Chamseddine, Michael Chopp, Zheng Gang Zhang, Dilip Moonka

Published Jan 25, 2021 · Vol. 12, No. 3 · pp. 185-198

Keywords: hepatocellular carcinoma (HCC), human cerebral endothelial cells-derived exosomes, microRNA-214, therapeutic efficacy, anti-cancer drug

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Tess A. O’Meara, Sara M. Tolaney

Published Jan 23, 2021 · Vol. 12, No. 5 · pp. 394-400

Keywords: breast cancer, immunotherapy, tumor mutational burden

Unravelling actionable biology using transcriptomic data to integrate mitotic index and Ki-67 in the management of lung neuroendocrine tumors Research Paper

Venkata S.K. Manem, Olga Sazonova, Andréanne Gagné, Michèle Orain, Babak Khoshkrood-Mansoori, Nathalie Gaudreault, Yohan Bossé, Philippe Joubert

Published Jan 22, 2021 · Vol. 12, No. 3 · pp. 209-220

Keywords: mitotic index, Ki-67, transcriptomics, lung neuroendocrine tumors, pathway analysis

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Shuichi Matsumura, Mikihito Nakamori, Toshiaki Tsuji, Tomoya Kato, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue

Published Jan 22, 2021 · Vol. 12, No. 4 · pp. 344-354

Keywords: oncolytic virus, herpes simplex virus, gastric cancer

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Francesco Jacopo Romano, Carmela Barbato, Maria Biglietto, Vincenzo Di Lauro, Dario Arundine, Roberto Fiorentino, Francesca Ambrosio, Maresa Cammarota, Bruno Chiurazzi, Livio Puglia, Sarah Scagliarini, Raffaella Ruocco, Carmen Mocerino, Ivana Cerillo, Maria Fiorella Brangi, Ferdinando Riccardi

Published Jan 19, 2021 · Vol. 12, No. 3 · pp. 221-229

Keywords: colorectal cancer, folinic acid, sodium levofolinate, thymidylate synthase, non oncogene addiction

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Rolando Pérez-Lorenzo, Stephanie O. Erjavec, Angela M. Christiano, Raphael Clynes

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 66-80

Keywords: anti-tumor antibodies, targeted therapy, immunotherapy, combination therapies, melanoma

Glioma immunoediting, a driver of tumor evolution, and the next battle for immunotherapy Editorial

Adam M. Sonabend, Roger Stupp, Catalina Lee-Chang, Hideho Okada

Published Dec 30, 2020 · Vol. 12, No. 1 · pp. 8-9

Keywords: immunoediting, glioma, glioblastoma, immunotherapy, resistance

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Jordan L. Kohlmeyer, David J. Gordon, Munir R. Tanas, Rebecca D. Dodd, Varun Monga, Benjamin W. Darbro, Dawn E. Quelle

Published Dec 26, 2020 · Vol. 12, No. 1 · pp. 10-14

Keywords: MPNST, RABL6A-RB1 signaling, CDK4/6 and MEK inhibitors, Ras, targeted cancer therapy

Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors Editorial

Erika J. Crosby, H. Kim Lyerly, Zachary C. Hartman

Published Dec 26, 2020 · Vol. 12, No. 1 · pp. 1-3

Keywords: breast cancer, tumor immunology animal models, T cell exhaustion, immune responses to cancer, tumor antigens/neoantigens

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Karim Abid, Maja Beck Popovic, Katia Balmas Bourloud, Jacqueline Schoumans, Joana Grand-Guillaume, Eric Grouzmann, Annick Mühlethaler-Mottet

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 49-60

Keywords: neuroblastoma, metanephrine, patient-derived xenograft, mouse model, Phenylethanolamine N-Methyltransferase

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Gerrit Spanier, Daniela Weidt, Dirk Hellwig, Johannes K.H. Meier, Torsten E. Reichert, Jirka Grosse

Published Dec 22, 2020 · Vol. 12, No. 1 · pp. 37-48

Keywords: FDG PET/CT, TLG, MTV, oral squamous cell carcinoma, prognostic value

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

Ahmed Elhassanny, Rene Escobedo, Daniel Ladin, Colin Burns, Rukiyah Van Dross

Published Dec 22, 2020 · Vol. 11, No. 52 · pp. 4788-4802

Keywords: calreticulin, endoplasmic reticulum stress, dendritic cells, endocannabinoid metabolite

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Krastan B. Blagoev, Roumen Iordanov, Mengxi Zhou, Tito Fojo, Susan E. Bates

Published Dec 19, 2020 · Vol. 12, No. 1 · pp. 15-21

Keywords: drug resistance, metastatic prostate cancer, exponential growth, tumor kinetics, cancer stem cells

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana, Reinhard Dummer

Published Dec 18, 2020 · Vol. 12, No. 2 · pp. 125-130

Keywords: spitzoid nevi, melanocytic lesion, dermatopathology, pediatric dermatology, diagnostic algorithm

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Alexandros Diamantis, Athina A. Samara, Dimitrios Symeonidis, Ioannis Baloyiannis, Dionysia Vasdeki, Maria Tolia, Georgios Volakakis, Georgios Mavrovounis, Konstantinos Tepetes

Published Dec 17, 2020 · Vol. 11, No. 52 · pp. 4813-4821

Keywords: gastrointestinal stromal tumor, mesenchymal tumors, synchronous malignancies

Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma Research Paper

Yuji Morine, Tohru Utsunomiya, Yu Saito, Shinichiro Yamada, Satoru Imura, Tetsuya Ikemoto, Akihiro Kitagawa, Yuta Kobayashi, Seiichiro Takao, Keisuke Kosai, Koshi Mimori, Yasuhito Tanaka, Mitsuo Shimada

Published Dec 16, 2020 · Vol. 11, No. 52 · pp. 4803-4812

Keywords: genome-wide analysis, methylation, tumor suppressor gene, prognostic biomarker, hepatocellular carcinoma

Harmonized pretreatment quantitative volume-based FDG-PET/CT parameters for prognosis of stage I–III breast cancer: Multicenter study Research Paper

Kazuhiro Kitajima, Yasuo Miyoshi, Tetsuro Sekine, Hiroyuki Takei, Kimiteru Ito, Akihiko Suto, Hayato Kaida, Kazunari Ishii, Hiromitsu Daisaki, Koichiro Yamakado

Published Dec 16, 2020 · Vol. 12, No. 2 · pp. 95-105

Keywords: breast cancer, survival, fluorodeoxyglucose (FDG), positron emission tomography-computed tomography (PET-CT), harmonization

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Hector A. Cuello, Gretel M. Ferreira, Cynthia A. Gulino, Alejandro Gomez Toledo, Valeria I. Segatori, Mariano R. Gabri

Published Dec 16, 2020 · Vol. 11, No. 52 · pp. 4822-4835

Keywords: glioma, glioblastoma, Lewis glycans, histone acetylation, N-glycans

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Divya Bhagirath, Thao Ly Yang, Theresa Akoto, Nikhil Patel, Laura Z. Tabatabai, Sharanjot Saini

Published Dec 15, 2020 · Vol. 11, No. 51 · pp. 4681-4692

Keywords: miR-4287, prostate cancer, chromosome 8p, EMT, SLUG

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MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Unravelling actionable biology using transcriptomic data to integrate mitotic index and Ki-67 in the management of lung neuroendocrine tumors Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Glioma immunoediting, a driver of tumor evolution, and the next battle for immunotherapy Editorial

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors Editorial

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma Research Paper

Harmonized pretreatment quantitative volume-based FDG-PET/CT parameters for prognosis of stage I–III breast cancer: Multicenter study Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs Research Paper

Tumor mutational burden as a predictor of immunotherapy response in breast cancer Research Perspective

Unravelling actionable biology using transcriptomic data to integrate mitotic index and Ki-67 in the management of lung neuroendocrine tumors Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Glioma immunoediting, a driver of tumor evolution, and the next battle for immunotherapy Editorial

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors Editorial

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ12,14 prostamide J2 Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma Research Paper

Harmonized pretreatment quantitative volume-based FDG-PET/CT parameters for prognosis of stage I–III breast cancer: Multicenter study Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper