The Oncosearch | Oncotarget

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, George Ansstas

Published Dec 13, 2020 · Vol. 11, No. 52 · pp. 4836-4844

Keywords: metastatic melanoma, immune checkpoint inhibitor, temozolomide, acquired resistance, beta-2 microglobulin

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

Shawn Sun, Florent L. Besson, Binsheng Zhao, Lawrence H. Schwartz, Laurent Dercle

Published Dec 13, 2020 · Vol. 11, No. 51 · pp. 4677-4680

Keywords: positron emission tomography, computed tomography, prognosis, lung cancer, immunotherapy

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Yvonne Cornejo, Min Li, Thanh H. Dellinger, Rachael Mooney, Masmudur M. Rahman, Grant McFadden, Karen S. Aboody, Mohamed Hammad

Published Dec 8, 2020 · Vol. 11, No. 51 · pp. 4693-4698

Keywords: oncolytic virotherapy, myxoma, NSCs, ovarian cancer

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Jan Roška, Lenka Wachsmannová, Lenka Hurbanová, Zuzana Šestáková, Thomas Mueller, Dana Jurkovičová, Miroslav Chovanec

Published Dec 5, 2020 · Vol. 11, No. 51 · pp. 4735-4753

Keywords: gene expression array, cisplatin, testicular germ cell tumors, prognostic biomarkers, pluripotency factors

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Katarina Reis, Jack L. Arbiser, Anders Hjerpe, Katalin Dobra, Pontus Aspenström

Published Dec 4, 2020 · Vol. 11, No. 50 · pp. 4637-4647

Keywords: malignant mesothelioma, actin dynamics, vimentin, cytoskeleton, imipramine blue

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Vishnu S. Mishra, Naveen Kumar, Masoom Raza, Seema Sehrawat

Published Dec 2, 2020 · Vol. 11, No. 51 · pp. 4754-4769

Keywords: precision neuroOncology, combination therapy, glioblastoma multiforme, pharmacological intervention, cytokine based proteomics

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Ahmad A. Nazem, Jacob Ruzevick, Manuel J. Ferreira Jr

Published Dec 2, 2020 · Vol. 11, No. 49 · pp. 4544-4553

Keywords: meningioma, skull base, NGS, sequencing, biomarker

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published Dec 1, 2020 · Vol. 11, No. 51 · pp. 4699-4721

Keywords: miR-708-5p, miR-708, erlotinib, paclitaxel, chemoresistance

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Adilson Kleber Ferreira, Brunella Cristofaro, Milene Cristina Menezes, Ana Karina de Oliveira, Alexandre Keiji Tashima, Robson Lopes de Melo, Cristiane Castilho Fernandes Silva, Miryam Guillermina Palomino Rodriguez, Daniela Cajado de Oliveira Souza Carvalho, Ricardo Alexandre de Azevedo, Paulo Luiz de Sá Junior, Lisley Inata Mambelli, Fernanda Vieira Portaro, Luc Pardanaud, Anne Eichmann, Osvaldo Augusto Sant’Anna, Mxarcella Faria

Published Nov 30, 2020 · Vol. 11, No. 51 · pp. 4770-4787

Keywords: alphastatin-C, angiogenesis, peptides, melanoma, angiostatic

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Jerusha Boyineni, Simone T. Sredni, Naira V. Margaryan, Lusine Demirkhanyan, Michael Tye, Robert Johnson, Fernando Gonzalez-Nilo, Mary J.C. Hendrix, Evgeny Pavlov, Marcelo B. Soares, Eleonora Zakharian, Sergey Malchenko

Published Nov 28, 2020 · Vol. 11, No. 50 · pp. 4613-4624

Keywords: polyphosphate, energy source, OXPHOS, glycolysis, metabolism

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Dileep Kumar M. Guruswamy, Kyathegowdana Doddi Srivinavasa Balaji, Kattepura Krishnappa Dharmappa, Shankar Jayarama

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4661-4676

Keywords: novel chalcone, Bcl2, caspase 3, BAX, receptor tyrosine kinase inhibitor

The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment Research Paper

Yuma Wada, Kazunori Tokuda, Yuji Morine, Shohei Okikawa, Shoko Yamashita, Tetsuya Ikemoto, Satoru Imura, Yu Saito, Shinichiro Yamada, Mitsuo Shimada

Published Nov 27, 2020 · Vol. 11, No. 49 · pp. 4593-4604

Keywords: CRLM, TU-100, HSC, CRC, IL-6

Immune-stimulatory (TK/Flt3L) gene therapy opens the door to a promising new treatment strategy against brainstem gliomas Research Perspective

Syed M. Faisal, Flor M. Mendez, Fernando Nunez, Maria G. Castro, Pedro R. Lowenstein

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4607-4612

Keywords: immunotherapy, gene therapy, thymidine kinase, Flt3L, DIPG

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

Madhav Sankunny, Charis Eng

Published Nov 25, 2020 · Vol. 11, No. 50 · pp. 4625-4636

Keywords: KLLN, nuclear export, NES, proteasomal degradation

High-fat diet-fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adipose tissue inflammation, local insulin-like growth factor release, and tumor associated macrophages Research Paper

Jackie Bader, Meredith Carson, Reilly Enos, Kandy Velazquez, Alexander Sougiannis, Udai Singh, William Becker, Mitzi Nagarkatti, Daping Fan, Angela Murphy

Published Nov 24, 2020 · Vol. 11, No. 49 · pp. 4554-4569

Keywords: colorectal cancer, obesity, metabolism, macrophage, inflammation

Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent Research Paper

Anastasia Kariagina, Elena Morozova, Reyhane Hoshyar, Mark D. Aupperlee, Mitchell A. Borin, Sandra Z. Haslam, Richard C. Schwartz

Published Nov 24, 2020 · Vol. 11, No. 48 · pp. 4465-4478

Keywords: oxybenzone, benzophenone-3, mammary tumorigenesis, dietary animal fat, breast cancer

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Bart Vanderborght, Kevin De Muynck, Sander Lefere, Anja Geerts, Helena Degroote, Xavier Verhelst, Hans Van Vlierberghe, Lindsey Devisscher

Published Nov 24, 2020 · Vol. 11, No. 48 · pp. 4504-4520

Keywords: hepatocellular carcinoma, hypoxia-inducible factor, antisense oligonucleotides, tumor microenvironment, experimental mouse model

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Paloma Bragado, Patricia Fernández-Nogueira, Neus Carbó, Pere Gascón

Published Nov 23, 2020 · Vol. 11, No. 49 · pp. 4541-4543

Keywords: breast cancer, TAFs, FGFR2, FGF5, trastuzumab

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper

Judith E. den Ouden, Guido J.R. Zaman, Jelle Dylus, Antoon M. van Doornmalen, Winfried R. Mulder, Yvonne Grobben, Wilhelmina E. van Riel, Joanne A. de Hullu, Rogier C. Buijsman, Anne M. van Altena

Published Nov 20, 2020 · Vol. 11, No. 49 · pp. 4570-4581

Keywords: ovarian cancer, chemotherapy sensitivity, prediction, ascites, proliferation assays

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Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment Research Paper

Immune-stimulatory (TK/Flt3L) gene therapy opens the door to a promising new treatment strategy against brainstem gliomas Research Perspective

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

High-fat diet-fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adipose tissue inflammation, local insulin-like growth factor release, and tumor associated macrophages Research Paper

Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent Research Paper

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Successful administration of sequential TVEC and pembrolizumab followed by Temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation Case Report

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment Research Paper

Immune-stimulatory (TK/Flt3L) gene therapy opens the door to a promising new treatment strategy against brainstem gliomas Research Perspective

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

High-fat diet-fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adipose tissue inflammation, local insulin-like growth factor release, and tumor associated macrophages Research Paper

Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent Research Paper

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper