The Oncosearch | Oncotarget

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Julin Shuxian Wong, Emma Warbrick, Borek Vojtesek, Jeffrey Hill, David Philip Lane

Published Jun 29, 2013 · Vol. 4, No. 7 · pp. 1019-1036

Keywords: c-Met, seeMet 2, monoclonal antibody, temperature sensitive & cryptic epitope

Radiation therapy induces the DNA damage response in peripheral blood Research Paper

Christopher J Bakkenist, R Kenneth Czambel, David A Clump, Joel S Greenberger, Jan H Beumer, John C Schmitz

Published Jun 26, 2013 · Vol. 4, No. 8 · pp. 1143-1148

Keywords: DNA damage response, ATM

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Jennifer J. Wheler, David Hong, Stephen G. Swisher, Gerald S. Falchook, Apostolia Maria Tsimberidou, Thorunn Helgason, Aung Naing, Bettzy Stephen, Filip Janku, Philip J. Stephens, Roman Yelensky, Razelle Kurzrock

Published Jun 10, 2013 · Vol. 4, No. 6 · pp. 890-898

Keywords: advanced thymoma, mTOR inhibitors, targeted therapy, thymic carcinoma

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Yunyun Jiang, Filip Janku, Vivek Subbiah, Laura S. Angelo, Aung Naing, Peter M. Anderson, Cynthia E. Herzog, Siqing Fu, Robert S. Benjamin, Razelle Kurzrock

Published Jun 5, 2013 · Vol. 4, No. 6 · pp. 884-889

Keywords: Ewing sarcoma, PTPRD, mutation, germline

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Jennifer Wheler, Gerald Falchook, Apostolia M. Tsimberidou, David Hong, Aung Naing, Sarina Piha-Paul, Su S. Chen, John Heymach, Siqing Fu, Su S. Chen, Bettzy Stephen, Jansina Y. Fok, Filip Janku, Razelle Kurzrock

Published Jun 4, 2013 · Vol. 4, No. 5 · pp. 772-784

Keywords: EGFR mutation, EGFR wild-type, non-small cell lung cancer, phase I trials, resistance, squamous cell

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong-Dong Wang, Geoffrey Neale, Susan Ragsdale, Virginia Valentine, Armita Bahrami, Jamshid Temirov, Stanley Pounds, Jinghui Zhang, Michael A. Dyer

Published Jun 1, 2013 · Vol. 4, No. 6 · pp. 844-859

Keywords: retinoblastoma, RB1, epigenetics

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

Ilia A. Droujinine, Mark A Eckert, Weian Zhao

Published May 31, 2013 · Vol. 4, No. 5 · pp. 651-664

Keywords: mesenchymal stem cells, cell therapy, stroma, microenvironment, tumor associated fibroblasts

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou, Razelle Kurzrock

Published May 1, 2013 · Vol. 4, No. 5 · pp. 705-714

Keywords: P53 mutations, PTEN loss, bevacizumab, Li-Fraumeni syndrome

A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal Research Paper

Filip Janku, Helen J. Huang, Laura S. Angelo, Razelle Kurzrock

Published Mar 23, 2013 · Vol. 4, No. 3 · pp. 463-473

Keywords: IGF-1R, OSI-906, intracellular glucose, autophagy, MCF7, HEK293

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Khoi Chu, Kimberkey M. Boley, Ricardo Moraes, Sanford H. Barsky, Fredika M. Robertson

Published Mar 21, 2013 · Vol. 4, No. 3 · pp. 446-462

Keywords: E-Cadherin, Inflammatory Breast Cander, Mesenchymal-Epithelial transition (MET), HIF-1Î±, Metabolism, Glycolysis

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal Research Paper

Hae-Kyung Lee, Susan Finniss, Simona Cazacu, Efrat Bucris, Amotz Ziv-Av, Cunli Xiang, Kevin Bobbitt, Sandra Rempel, Laura Hasselbach, Tom Mikkelsen, Shimon Slavin, Chaya Brodie

Published Feb 28, 2013 · Vol. 4, No. 2 · pp. 346-361

Keywords: miRNA delivery, mesenchymal stem cells, glioma, exosomes

BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance Research Paper

Gerald S. Falchook, Jonathan C. Trent, Michael C. Heinrich, Carol Beadling, Janice Patterson, Christel C. Bastida, Samuel C. Blackman, Razelle Kurzrock

Published Feb 25, 2013 · Vol. 4, No. 2 · pp. 310-315

Keywords: Gastrointestinal stromal tumor, Dabrafenib, GSK2118436, BRAF mutation, BRAF inhibition, V600E

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Joshua E. Allen, Wafik S. El-Deiry

Published Feb 18, 2013 · Vol. 4, No. 2 · pp. 184-191

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Ishwaria Subbiah, Vivek Subbiah, Apostolia M Tsimberidou, Aung Naing, Ahmed Kaseb, Javle Milind, Siqing Fu, David S Hong, Sarina Piha-Paul, Jenifer Wheler, Kenneth Hess, Filip Janku, Gerald Falchook, Robert A Wolff, Razelle Kurzrock

Published Jan 27, 2013 · Vol. 4, No. 1 · pp. 153-162

Keywords: Gallbladder Cancer, Cholangiocarcinoma, Phase 1 trials

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Gerald S. Falchook, Aung Naing, David S. Hong, Ralph G. Zinner, Siqing Fu, Sarina A. Piha-Paul, Apostolia M. Tsimberidou, Sonia K. Morgan-Linnell, Yunfang Jiang, Christel C. Bastida, Jennifer J. Wheler, Razelle Kurzrock

Published Jan 14, 2013 · Vol. 4, No. 1 · pp. 118-127

Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer Research Paper

W. Nathaniel Brennen, Shuangling Chen, Samuel R. Denmeade, John T. Isaacs

Published Jan 13, 2013 · Vol. 4, No. 1 · pp. 106-117

Keywords: Mesenchymal Stem Cells, MSC, Inflammation, Prostate Cancer, Drug Delivery, CAF

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes Research Paper

Filip Janku, Jennifer J. Wheler, Aung Naing, Vanda M. T. Stepanek, Gerald S. Falchook, Siqing Fu, Ignacio Garrido-Laguna, Apostolia M. Tsimberidou, Sarina A. Piha-Paul, Stacy L. Moulder, J. Jack Lee, Rajyalakshmi Luthra, David S. Hong, Razelle Kurzrock

Published Nov 30, 2012 · Vol. 3, No. 12 · pp. 1566-1575

Keywords: PIK3CA mutation, phenotypic taxonomy, clinical outcome

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Nicola Amodio, Marzia Leotta, Dina Bellizzi, Maria Teresa Di Martino, Patrizia D'Aquila, Marta Lionetti, Fernanda Fabiani, Emanuela Leone, Anna Maria GullÃ, Giuseppe Passarino, Michele Caraglia, Massimo Negrini, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone

Published Oct 21, 2012 · Vol. 3, No. 10 · pp. 1246-1258

Keywords: miRNA, miR-29b, multiple myeloma, DNMT

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Luigi Aurisicchio, Emanuele Marra, Giuseppe Roscilli, Rita Mancini, Gennaro Ciliberto

Published Aug 10, 2012 · Vol. 3, No. 8 · pp. 744-758

Keywords: cancer, ErbB3, monoclonal antibodies, mechanism of action, clinical trials

Regulation of p53: a collaboration between Mdm2 and Mdmx Review

Dongsheng Pei, Yanping Zhang, Junnian Zheng

Published Mar 10, 2012 · Vol. 3, No. 3 · pp. 228-235

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Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Radiation therapy induces the DNA damage response in peripheral blood Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal Research Paper

BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance Research Paper

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer Research Paper

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes Research Paper

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Regulation of p53: a collaboration between Mdm2 and Mdmx Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Research Paper

Radiation therapy induces the DNA damage response in peripheral blood Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Analysis of an MD Anderson Cancer Center Phase I Population Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal Research Paper

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism Research Paper

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal Research Paper

BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance Research Paper

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Dual EGFR inhibition in combination with anti-VEGF treatment: A phase I clinical trial in non-small cell lung cancer Research Paper

Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer Research Paper

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes Research Paper

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

The promise of anti-ErbB3 monoclonals as new cancer therapeutics Review

Regulation of p53: a collaboration between Mdm2 and Mdmx Review