The Oncosearch | Oncotarget

Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-ÎºB signaling pathway Research Paper

Ning Zhang, Eagle S. H. Chu, Jingwan Zhang, Xiaoxing Li, Qiaoyi Liang, Jie Chen, Minhu Chen, Narci Teoh, Geoffrey Farrell, Joseph J. Y. Sung, Jun Yu

Published Jul 13, 2014 · Vol. 5, No. 18 · pp. 8330-8340

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype Research Paper

Katia Beider, Hanna Bitner, Merav Leiba, Odit Gutwein, Maya Koren-Michowitz, Olga Ostrovsky, Michal Abraham, Hanna Wald, Eithan Galun, Amnon Peled, Arnon Nagler

Published Jul 12, 2014 · Vol. 5, No. 22 · pp. 11283-11296

The NF1 gene revisited â€“ from bench to bedside Review

Yoon-Sim Yap, John R. McPherson, Choon-Kiat Ong, Steven G. Rozen, Bin-Tean Teh, Ann S. G. Lee, David F. Callen

Published Jul 9, 2014 · Vol. 5, No. 15 · pp. 5873-5892

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer Research Paper

Chunsheng Li, Junying Wang, Jia Hu, Yi Feng, Kosei Hasegawa, Xiaohui Peng, Xingmei Duan, Aizhi Zhao, John L. Mikitsh, Vladimir R. Muzykantov, Ann-Marie Chacko, Daniel A. Pryma, Steven M. Dunn, George Coukos

Published Jul 8, 2014 · Vol. 5, No. 16 · pp. 6994-7012

Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer Research Paper

Janet Mendonca, Anup Sharma, Hae-Soo Kim, Hans Hammers, Alan Meeker, Angelo De Marzo, Michael Carducci, Michael Kauffman, Sharon Shacham, Sushant Kachhap

Published Jul 7, 2014 · Vol. 5, No. 15 · pp. 6102-6112

Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Peng Liu, Zhipeng Wang, Sarah Brown, Vinodh Kannappan, Patricia Erebi Tawari, Wenguo Jiang, Juan M. Irache, James Z. Tang, Stephen Britland, Angel L. Armesilla, John L. Darling, Weiguang Wang, Weiguang Wang Wang

Published Jul 4, 2014 · Vol. 5, No. 17 · pp. 7471-7485

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Christopher T. Cummings, Rachel M.A. Linger, Rebecca A. Cohen, Susan Sather, Gregory D. Kirkpatrick, Kurtis D. Davies, Deborah DeRyckere, H. Shelton Earp, Douglas K. Graham

Published Jun 26, 2014 · Vol. 5, No. 21 · pp. 10434-10445

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth Research Paper

Ningning Liu, Xiaofen Li, Hongbiao Huang, Chong Zhao, Siyan Liao, Changshan Yang, Shouting Liu, Wenbin Song, Xiaoyu Lu, Xiaoying Lan, Xin Chen, Songgang Yi, Li Xu, Lili Jiang, Canguo Zhao, Xiaoxian Dong, Ping Zhou, Shujue Li, Shunqing Wang, Xianping Shi, Ping Q. Dou, Xuejun Wang, Jinbao Liu

Published Jun 18, 2014 · Vol. 5, No. 14 · pp. 5453-5471

Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin Research Paper

Chakrapani Tripathi, Brij Nath Tewari, Ranjana Kumari Kanchan, Khemraj Singh Baghel, Naveen Nautiyal, Richa Shrivastava, Harbeer Kaur, Madan Lal Bramha Bhatt, Smrati Bhadauria

Published Jun 17, 2014 · Vol. 5, No. 14 · pp. 5350-5368

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Orkhan Isayev, Vanessa Rausch, Nathalie Bauer, Li Liu, Pei Fan, Yiyao Zhang, Jury Gladkich, Clifford C. Nwaeburu, JÃ¼rgen Mattern, Martin Mollenhauer, Felix RÃ¼ckert, Sebastian Zach, Uwe Haberkorn, Wolfgang Gross, Frank SchÃ¶nsiegel, Alexandr V. Bazhin, Ingrid Herr

Published Jun 15, 2014 · Vol. 5, No. 13 · pp. 5177-5189

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia Research Paper

Yuh-Ying Yeh, Rong Chen, Joshua Hessler, Emilia Mahoney, Amy M. Lehman, Nyla A. Heerema, Michael R. Grever, William Plunkett, John C. Byrd, Amy J. Johnson

Published Jun 12, 2014 · Vol. 6, No. 5 · pp. 2667-2679

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Nianli Liu, Chaohui Zuo, Xiaohong Wang, Tianran Chen, Darong Yang, Jing Wang, Haizhen Zhu

Published Jun 6, 2014 · Vol. 5, No. 13 · pp. 4959-4971

Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells Research Paper

Bruna Corominas-Faja, Elisabet CuyÃ s, Juan Gumuzio, Joaquim Bosch-Barrera, Olatz Leis, Ãngel G. Martin, Javier A. Menendez

Published Jun 5, 2014 · Vol. 5, No. 18 · pp. 8306-8316

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding Research Paper

Akwasi Agyeman, Babal K. Jha, Tapati Mazumdar, Janet A. Houghton

Published May 31, 2014 · Vol. 5, No. 12 · pp. 4492-4503

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

Filip Janku, Ahmed O. Kaseb, Apostolia M. Tsimberidou, Robert A. Wolff, Razelle Kurzrock

Published May 30, 2014 · Vol. 5, No. 10 · pp. 3012-3022

Keywords: hepatocellular carcinoma, PI3K, AKT, mTOR, next generation sequencing

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Wenqiang Cao, Xiaoling Li, Shanyuan Zheng, Wenjie Zheng, Yum-shing Wong, Tianfeng Chen

Published May 26, 2014 · Vol. 5, No. 17 · pp. 7431-7445

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection Research Paper

Jie Shen, Qiang Hu, Michael Schrauder, Li Yan, Dan Wang, Leonardo Medico, Yuqing Guo, Song Yao, Qianqian Zhu, Biao Liu, Maochun Qin, Matthias W. Beckmann, Peter A. Fasching, Reiner Strick, Candace S. Johnson, Christine B. Ambrosone, Hua Zhao, Song Liu

Published May 26, 2014 · Vol. 5, No. 14 · pp. 5284-5294

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

Rabih Said, Yang Ye, David S. Hong, Filip Janku, Siqing Fu, Aung Naing, Jennifer J. Wheler, Razelle Kurzrock, Christoforos Thomas, Gary A. Palmer, Kenneth R. Hess, Kenneth Aldape, Apostolia M. Tsimberidou

Published May 25, 2014 · Vol. 5, No. 11 · pp. 3871-3879

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

Stephen P. Hack, Jean-Marie Bruey, Hartmut Koeppen

Published May 24, 2014 · Vol. 5, No. 10 · pp. 2866-2880

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper

Filip Janku, Cecile Rose T. Vibat, Karena Kosco, Veronica R. Holley, Goran Cabrilo, Funda Meric-Bernstam, Vanda M. Stepanek, Patrick P. Lin, Lorieta Leppin, Latifa Hassaine, Jason C. Poole, Razelle Kurzrock, Mark G. Erlander

Published May 13, 2014 · Vol. 5, No. 11 · pp. 3607-3610

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Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-ÎºB signaling pathway Research Paper

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype Research Paper

The NF1 gene revisited â€“ from bench to bedside Review

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer Research Paper

Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer Research Paper

Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth Research Paper

Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin Research Paper

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia Research Paper

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells Research Paper

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding Research Paper

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection Research Paper

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-ÎºB signaling pathway Research Paper

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype Research Paper

The NF1 gene revisited â€“ from bench to bedside Review

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer Research Paper

Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer Research Paper

Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth Research Paper

Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin Research Paper

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia Research Paper

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells Research Paper

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding Research Paper

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection Research Paper

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease Research Paper