The Oncosearch | Oncotarget

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Soo-Im Choi, Seo-Yeon Kim, Jaeha Lee, Eun-Wie Cho, In-Gyu Kim

Published Sep 8, 2014 · Vol. 5, No. 20 · pp. 9823-9837

Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes Research Paper

Xiaoping Su, Gabriel G. Malouf, Yunxin Chen, Jianping Zhang, Hui Yao, Vicente Valero, John N. Weinstein, Jean-Philippe Spano, Funda Meric-Bernstam, David Khayat, Francisco J. Esteva

Published Sep 8, 2014 · Vol. 5, No. 20 · pp. 9864-9876

Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities Review

Vivien LandrÃ©, Barak Rotblat, Sonia Melino, Francesca Bernassola, Gerry Melino

Published Sep 3, 2014 · Vol. 5, No. 18 · pp. 7988-8013

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper

Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Andreas Herrlich, Matthew J. Ellis, Brian A. Van Tine, Loren S. Michel

Published Sep 2, 2014 · Vol. 5, No. 19 · pp. 9281-9294

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Shalana Oâ€™Brien, Vita M. Golubovskaya, Jeffrey Conroy, Song Liu, Dan Wang, Biao Liu, William G. Cance

Published Aug 25, 2014 · Vol. 5, No. 17 · pp. 7945-7959

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Xin Chen, Xianping Shi, Chong Zhao, Xiaofen Li, Xiaoying Lan, Shouting Liu, Hongbiao Huang, Ningning Liu, Siyan Liao, Dan Zang, Wenbin Song, Quentin Liu, Bing Z. Carter, Ping Q. Dou, Xuejun Wang, Jinbao Liu

Published Aug 22, 2014 · Vol. 5, No. 19 · pp. 9118-9132

Keywords: Auranofin, proteasome, chronic myelogenous leukemia, imatinib resistance, Bcr-Abl

Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer Research Paper

Zachary C. Dobbin, Ashwini A. Katre, Adam D. Steg, Britt K. Erickson, Monjri M. Shah, Ronald D. Alvarez, Michael G. Conner, David Schneider, Dongquan Chen, Charles N. Landen

Published Aug 19, 2014 · Vol. 5, No. 18 · pp. 8750-8764

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Burhan Hassan, Argun Akcakanat, Takafumi Sangai, Kurt W. Evans, Farrell Adkins, Agda Karina Eterovic, Hao Zhao, Ken Chen, Huiqin Chen, Kim-Anh Do, Shelly M. Xie, Ashley M. Holder, Aung Naing, Gordon B. Mills, Funda Meric-Bernstam

Published Aug 10, 2014 · Vol. 5, No. 18 · pp. 8544-8557

Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials Clinical Research Papers

Rabih Said, Yang Ye, Gerald Steven Falchook, Filip Janku, Aung Naing, Ralph Zinner, George R. Blumenschein Jr, Siqing Fu, David S. Hong, Sarina Anne Piha-Paul, Jennifer J. Wheler, Razelle Kurzrock, Gary A. Palmer, Kenneth Aldape, Kenneth . R Hess, Apostolia Maria Tsimberidou

Published Aug 10, 2014 · Vol. 5, No. 19 · pp. 8937-8946

Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer Research Paper

Anna Lena Ress, Verena Stiegelbauer, Daniela Schwarzenbacher, Alexander Deutsch, Samantha Perakis, Hui Ling, Cristina Ivan, George Adrian Calin, Beate Rinner, Armin Gerger, Martin Pichler

Published Aug 8, 2014 · Vol. 5, No. 18 · pp. 8492-8502

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Cecilia Evangelisti, Camilla Evangelisti, Gabriella Teti, Francesca Chiarini, Mirella Falconi, Fraia Melchionda, Andrea Pession, Alice Bertaina, Franco Locatelli, James A. McCubrey, Dong Jae Beak, Robert Bittman, Susan Pyne, Nigel J. Pyne, Alberto M. Martelli

Published Aug 6, 2014 · Vol. 5, No. 17 · pp. 7886-7901

Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model Research Paper

Young-Eun Kim, Sanghoon Kwon, Guang Wu, Dongbum Kim, Byoung Kwon Park, Jeong-A Park, Kyung-Chan Choi, Doo-Sik Kim, Hyung-Joo Kwon, Younghee Lee

Published Aug 4, 2014 · Vol. 5, No. 18 · pp. 8402-8415

A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling Research Paper

Romain Boidot, Samuel Branders, Thibault Helleputte, Laila Illan Rubio, Pierre Dupont, Olivier Feron

Published Jul 31, 2014 · Vol. 5, No. 16 · pp. 6947-6963

CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma Research Paper

Lei Jiang, Yi-Dong Yang, Li Fu, Weiqi Xu, Dabin Liu, Qiaoyi Liang, Xiang Zhang, Lixia Xu, Xin-Yuan Guan, Bin Wu, Joseph J.Y. Sung, Jun Yu

Published Jul 31, 2014 · Vol. 5, No. 17 · pp. 7663-7676

MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer Research Paper

Sheema Khan, Mara C. Ebeling, Mohd S. Zaman, Mohammed Sikander, Murali M. Yallapu, Neeraj Chauhan, Ashley M. Yacoubian, Stephen W. Behrman, Nadeem Zafar, Deepak Kumar, Paul A. Thompson, Meena Jaggi, Subhash C. Chauhan

Published Jul 30, 2014 · Vol. 5, No. 17 · pp. 7599-7609

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma Research Paper

Laia Rosich, Arnau Montraveta, SÃlvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Jocabed RoldÃ¡n, Marta Aymerich, Itziar Salaverria, SÃlvia BeÃ, ElÃas Campo, Patricia PÃ©rez-GalÃ¡n, GaÃ«l RouÃ©, Dolors Colomer

Published Jul 25, 2014 · Vol. 5, No. 16 · pp. 6788-6800

Structural basis of nSH2 regulation and lipid binding in PI3KÎ± Priority Research Paper

Michelle S. Miller, Oleg Schmidt-Kittler, David M. Bolduc, Evan T. Brower, Daniele Chaves-Moreira, Marc Allaire, Kenneth W. Kinzler, Ian G. Jennings, Philip E. Thompson, Philip A. Cole, L. Mario Amzel, Bert Vogelstein, Sandra B. Gabelli

Published Jul 25, 2014 · Vol. 5, No. 14 · pp. 5198-5208

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis Research Paper

Sze Ue Iris Luk, Hui Xue, Hongwei Cheng, Dong Lin, Peter W. Gout, Ladan Fazli, Colin C. Collins, Martin E. Gleave, Yuzhuo Wang

Published Jul 17, 2014 · Vol. 5, No. 16 · pp. 6896-6908

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Jeffrey Wojton, Walter Hans Meisen, Naduparambil K. Jacob, Amy Haseley Thorne, Jayson Hardcastle, Nicholas Denton, Zhengtao Chu, Nina Dmitrieva, Rachel Marsh, Erwin G. Van Meir, Chang-Hyuk Kwon, Arnab Chakravarti, Xiaoyang Qi, Balveen Kaur

Published Jul 17, 2014 · Vol. 5, No. 20 · pp. 9703-9709

Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome Research Paper

Emily L. Putiri, Rochelle L. Tiedemann, Chunsheng Liu, Jeong-Hyeon Choi, Keith D. Robertson

Published Jul 14, 2014 · Vol. 5, No. 15 · pp. 6338-6352

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TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes Research Paper

Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities Review

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials Clinical Research Papers

Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer Research Paper

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model Research Paper

A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling Research Paper

CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma Research Paper

MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer Research Paper

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma Research Paper

Structural basis of nSH2 regulation and lipid binding in PI3KÎ± Priority Research Paper

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis Research Paper

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1 Research Paper

Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes Research Paper

Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities Review

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Research Paper

FAK Inhibition with Small Molecule Inhibitor Y15 Decreases Viability, Clonogenicity, and Cell Attachment in Thyroid Cancer Cell Lines and Synergizes with Targeted Therapeutics Research Paper

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms Research Paper

Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials Clinical Research Papers

Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer Research Paper

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics Research Paper

Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model Research Paper

A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling Research Paper

CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma Research Paper

MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer Research Paper

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma Research Paper

Structural basis of nSH2 regulation and lipid binding in PI3KÎ± Priority Research Paper

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis Research Paper

SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma Research Paper

Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome Research Paper