The Oncosearch | Oncotarget

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Bart Vanderborght, Kevin De Muynck, Sander Lefere, Anja Geerts, Helena Degroote, Xavier Verhelst, Hans Van Vlierberghe, Lindsey Devisscher

Published Nov 24, 2020 · Vol. 11, No. 48 · pp. 4504-4520

Keywords: hepatocellular carcinoma, hypoxia-inducible factor, antisense oligonucleotides, tumor microenvironment, experimental mouse model

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Alec J. Kacew, Harita Dharaneeswaran, Gabriel J. Starrett, Manisha Thakuria, Nicole R. LeBoeuf, Ann W. Silk, James A. DeCaprio, Glenn J. Hanna

Published Nov 17, 2020 · Vol. 11, No. 47 · pp. 4401-4410

Keywords: cancer, genomics, immunotherapy, Merkel cell carcinoma, precision medicine

Immune profiling of the bone marrow microenvironment in patients with high-risk localized prostate cancer Research Paper

Erika Heninger, Nan Sethakorn, David Kosoff, Peiman Hematti, Morgan D. Kuczler, Kenneth J. Pienta, Joshua M. Lang

Published Nov 10, 2020 · Vol. 11, No. 46 · pp. 4253-4265

Keywords: prostate cancer, bone marrow, tumor microenvironment, immune profiling, immune landscape

RNA sequencing analyses reveal differentially expressed genes and pathways as Notch2 targets in B-cell lymphoma Research Paper

Ashok Arasu, Pavithra Balakrishnan, Thirunavukkarasu Velusamy

Published Nov 4, 2020 · Vol. 11, No. 48 · pp. 4527-4540

Keywords: SMZL, Notch2, RNA sequencing, PI3K/AKT, NF-kB

T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma Research Perspective

Christie P.M. Verkleij, Kristine A. Frerichs, Marloes Broekmans, Saida Absalah, Patricia W.C. Maas-Bosman, Sandy Kruyswijk, Inger S. Nijhof, Tuna Mutis, Sonja Zweegman, Niels W.C.J. van de Donk

Published Oct 24, 2020 · Vol. 11, No. 45 · pp. 4076-4081

Keywords: multiple myeloma, bispecific antibody, immunotherapy, BCMA, CD38

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

Vic Hart, Hannah Gautrey, John Kirby, Alison Tyson-Capper

Published Oct 22, 2020 · Vol. 11, No. 46 · pp. 4338-4357

Keywords: HER2, Δ16-HER2, splice variant, breast cancer, trastuzumab

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Marion Dubuissez, Sonia Paget, Souhila Abdelfettah, Nathalie Spruyt, Vanessa Dehennaut, Gaylor Boulay, Ingrid Loison, Clementine de Schutter, Brian R. Rood, Martine Duterque-Coquillaud, Xavier Leroy, Dominique Leprince

Published Oct 21, 2020 · Vol. 11, No. 45 · pp. 4138-4154

Keywords: HIC1, CXCL12, SDF1, α-SMA, Acta2

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Michael R. Mortensen, Jacqueline Mock, Marco Bertolini, Marco Stringhini, Marco Catalano, Dario Neri

Published Oct 6, 2020 · Vol. 11, No. 44 · pp. 3972-3983

Keywords: immunotherapy, immunocytokines, EDB of fibronectin, antibody-cytokine fusion proteins, engineered cytokine

Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model Research Paper

Robert A. Kazmierczak, Bakul Dhagat-Mehta, Elke Gulden, Li Lee, Lixin Ma, Clintin P. Davis-Stober, Austen A. Barnett, Chiswili Yves Chabu

Published Oct 4, 2020 · Vol. 11, No. 44 · pp. 3943-3958

Keywords: salmonella, cancer targeting, prostate cancer, immunotherapy, TRAMP

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

Nicolai Skovbjerg Arildsen, Ingrid Hedenfalk

Published Sep 8, 2020 · Vol. 11, No. 40 · pp. 3660-3674

Keywords: ovarian clear cell cancer, simvastatin, CID-1067700, Rho GTPase, actin

Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism Research Paper

Archis Bagati, Timothy C. Hutcherson, Zethan Koch, Joseph Pechette, Hossein Dianat, Cory Higley, Lisa Chiu, Yesul Song, Jay Shah, Elana Chazen, Andrew Nicolais, Peter Casey, Kyle Thompson, Kevin Burke, Mikhail A. Nikiforov, Jennifer Zirnheld, Shoshanna N. Zucker

Published Aug 27, 2020 · Vol. 11, No. 37 · pp. 3443-3458

Keywords: non-thermal plasma, gap junction, tirapazamine, melanoma, intercellular communication

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

Tiziano Ongaro, Baptiste Gouyou, Marco Stringhini, Riccardo Corbellari, Dario Neri, Alessandra Villa

Published Aug 23, 2020 · Vol. 11, No. 41 · pp. 3698-3711

Keywords: tumor targeting, fibronectin, immunocytokines, interleukin-2, protein engineering

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Luigi Scotto, Xavier J. Serrano, Kelly Zullo, Cristina Kinahan, Changchun Deng, Ahmed Sawas, Susan Bates, Owen A. O’Connor

Published Aug 18, 2020 · Vol. 11, No. 37 · pp. 3432-3442

Keywords: lymphoma, HDAC inhibitor, ATM inhibitor, p21, cell cycle

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

Victor Hugo de Souza, Josiane Bazzo de Alencar, Bruna Tiaki Tiyo, Hugo Vicentin Alves, Evelyn Castillo Lima Vendramini, Ana Maria Sell, Jeane Eliete Laguila Visentainer

Published Aug 13, 2020 · Vol. 11, No. 36 · pp. 3405-3417

Keywords: cytokines, alleles, polymorphism, single nucleotide, inflammation

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

Adélia Mendes, Ramona Jühlen, Valérie Martinelli, Birthe Fahrenkrog

Published Aug 11, 2020 · Vol. 11, No. 36 · pp. 3371-3386

Keywords: CRM1, NUP214, leukemia, nuclear export, nucleoporin

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Angel Núñez-Marrero, Nelly Arroyo, Lenin Godoy, Mohammad Zillur Rahman, Jaime L. Matta, Julie Dutil

Published Aug 5, 2020 · Vol. 11, No. 37 · pp. 3420-3431

Keywords: breast cancer, interleukin-12 (IL-12), IL-12 signaling, genetic association, single nucleotide polymorphisms

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

Christina Walter, Andreas Hartkopf, Andre Koch, Marion Klaumünzer, Martin Schulze, Eva-Maria Grischke, Florin-Andrei Taran, Sara Brucker, Florian Battke, Saskia Biskup

Published Aug 1, 2020 · Vol. 11, No. 35 · pp. 3279-3285

Keywords: breast cancer, genetics, next-generation sequencing, actionable mutations

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Guilherme Rossi Assis-Mendonça, André Fattori, Rafael Malagoli Rocha, Gustavo Jacob Lourenço, Márcia Torresan Delamain, Suely Nonogaki, Vladmir Cláudio Cordeiro de Lima, Gisele Wally Braga Colleoni, Cármino Antonio de Souza, Fernando Augusto Soares, Carmen Silvia Passos Lima, José Vassallo

Published Jul 25, 2020 · Vol. 11, No. 33 · pp. 3153-3173

Keywords: follicular lymphoma, tumor microenvironment, immunohistochemistry, single nucleotide polymorphisms, prognosis

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

Aman Chauhan, Riham El-Khouli, Timothy Waits, Rohitashva Agrawal, Fariha Siddiqui, Zachary Tarter, Millicent Horn, Heidi Weiss, Elizabeth Oates, B. Mark Evers, Lowell Anthony

Published Jul 22, 2020 · Vol. 11, No. 32 · pp. 3061-3068

Keywords: gallium-68 DOTATATE, neuroendocrine diagnosis, NET

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper

Simona Ruxandra Volovat, Tudor-Eliade Ciuleanu, Piotr Koralewski, Juneko E. Grilley Olson, Adina Croitoru, Krassimir Koynov, Stefano Stabile, Giulio Cerea, Atsushi Osada, Iulian Bobe, Constantin Volovat

Published Jul 15, 2020 · Vol. 11, No. 33 · pp. 3105-3117

Keywords: cisplatin, NC-6004, non-small cell lung cancer, biliary tract cancer, bladder cancer

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Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Immune profiling of the bone marrow microenvironment in patients with high-risk localized prostate cancer Research Paper

RNA sequencing analyses reveal differentially expressed genes and pathways as Notch2 targets in B-cell lymphoma Research Paper

T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma Research Perspective

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model Research Paper

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model Research Paper

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Immune profiling of the bone marrow microenvironment in patients with high-risk localized prostate cancer Research Paper

RNA sequencing analyses reveal differentially expressed genes and pathways as Notch2 targets in B-cell lymphoma Research Paper

T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma Research Perspective

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors Research Paper

Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model Research Paper

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism Research Paper

A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo Research Paper

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis Meta-Analysis

Targeted CRM1-inhibition perturbs leukemogenic NUP214 fusion proteins and exerts anti-cancer effects in leukemia cell lines with NUP214 rearrangements Research Paper

SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women Research Paper

Sequencing for an interdisciplinary molecular tumor board in patients with advanced breast cancer: experiences from a case series Research Paper

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course Research Paper

Post FDA approval analysis of 200 gallium-68 DOTATATE imaging: A retrospective analysis in neuroendocrine tumor patients Research Paper

A multicenter, single-arm, basket design, phase II study of NC-6004 plus gemcitabine in patients with advanced unresectable lung, biliary tract, or bladder cancer Research Paper