The Oncosearch | Oncotarget

Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma Research Paper

Sarah Adriana Scuderi, Giovanna Casili, Alessia Filippone, Marika Lanza, Rossella Basilotta, Raffaella Giuffrida, Stefania Munaò, Lorenzo Colarossi, Anna Paola Capra, Emanuela Esposito, Irene Paterniti

Published Dec 1, 2021 · Vol. 12, No. 25 · pp. 2459-2473

Keywords: oral squamous cell carcinoma (OSCC), tongue squamous cell carcinoma (TSCC), prolyl-oligopeptidase (POP), angiogenesis, apoptosis

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Vandana M. Sagar, Kathyrn Herring, Stuart Curbishley, James Hodson, Peter Fletcher, Salil Karkhanis, Homoyon Mehrzad, Pankaj Punia, Tahir Shah, Shishir Shetty, Yuk Ting Ma

Published Nov 16, 2021 · Vol. 12, No. 24 · pp. 2338-2350

Keywords: hepatocellular carcinoma, biomarker, PIVKA-II

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

Benny Zhitomirsky, Yehuda G. Assaraf

Published Oct 28, 2021 · Vol. 13, No. 1 · pp. 585-586

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Christina Schmitt, Anna-Alice Schulz, Ria Winkelmann, Kevin Smith, Peter J. Wild, Melanie Demes

Published Oct 5, 2021 · Vol. 12, No. 22 · pp. 2273-2282

Keywords: next-generation sequencing (NGS), non-small cell lung cancer (NSCLC), fluorescence in situ hybridization (FISH), MET amplification, routine diagnostics

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Shuai Zhao, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1970-1979

Keywords: Smurf2, CDK4/6 inhibition, HIF1alpha, hypoxia, cancer therapy

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Nicholas Cho, Sooah Ko, Monica Shokeen

Published Sep 7, 2021 · Vol. 12, No. 20 · pp. 2039-2050

Keywords: near-infrared (NIR) fluorescence, multiple myeloma (MM), cluster of differentiation 38 (CD38), antibody-drug conjugate (ADC), small animal optical imaging

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Ricardo Paz-Fumagalli, Jacob Core, Carlos Padula, Seyed Montazeri, John McKinney, Gregory Frey, Zlatko Devcic, Andrew Lewis, Charles Ritchie, Kabir Mody, Sunil Krishnan, Beau Toskich

Published Aug 21, 2021 · Vol. 12, No. 20 · pp. 2075-2088

Keywords: Yttrium-90, radioembolization, cholangiocarcinoma, angiography, radiation dosimetry

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

Role of microRNAs in glioblastoma Review

Ming Chen, Zdravka Medarova, Anna Moore

Published Jul 30, 2021 · Vol. 12, No. 17 · pp. 1707-1723

Keywords: glioblastoma, microRNA, miRNA-based therapies, miRNA delivery

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Miguel Vizoso, Jacco van Rheenen

Published Jul 29, 2021 · Vol. 12, No. 17 · pp. 1651-1662

Keywords: targeted DNA methylation, CRISPR/Cas9-based system, IGFBP2, epithelial-to-mesenchymal transition

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Nikolai Petrov, Hee-Sheung Lee, Mikhail Liskovykh, Marie-Paule Teulade-Fichou, Hiroshi Masumoto, William C. Earnshaw, Yves Pommier, Vladimir Larionov, Natalay Kouprina

Published Jun 27, 2021 · Vol. 12, No. 15 · pp. 1444-1456

Keywords: chromosome instability, CIN, platinum-derived G4-quadruplexes, telomere dysfunction, human artificial chromosome

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

The role of dynamic phenotypes in cancer Research Perspective

Luana S. Lenz, Guido Lenz

Published Jun 19, 2021 · Vol. 12, No. 19 · pp. 1962-1965

Keywords: dynamic phenotype, fitness, tumor resistance, tumor evolution, single cell

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Grace Fangmin Tan, Jason Yongsheng Chan

Published Jun 14, 2021 · Vol. 12, No. 19 · pp. 1953-1955

Keywords: rare cancer, single cell sequencing, chemoresistance, spatial transcriptomics

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

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Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma Research Paper

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Role of microRNAs in glioblastoma Review

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

The role of dynamic phenotypes in cancer Research Perspective

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma Research Paper

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Correction: Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Role of microRNAs in glioblastoma Review

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

The role of dynamic phenotypes in cancer Research Perspective

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper