The Oncosearch | Oncotarget

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Viola Ellison, George K. Annor, Clara Freedman, Gu Xiao, Devon Lundine, Elzbieta Freulich, Carol Prives, Jill Bargonetti

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1128-1146

Keywords: mutant p53, gain-of-function, oligomerization, DNA replication, frame-shift

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Lina Alhalhooly, Babak Mamnoon, Jiha Kim, Sanku Mallik, Yongki Choi

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1165-1177

Keywords: cellular stiffness, roughness, adhesion, drug resistance, hypoxia

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

Shweta Kishor Sonawane, Subashchandrabose Chinnathambi

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1083-1099

Keywords: Alzheimer’s disease, Tau protein, Tau PTMs, Tau glycation, Tau glycation inhibition

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper

Tracey White, Szabolcs Szelinger, Janine LoBello, Amy King, Jessica Aldrich, Nathan Garinger, Matthew Halbert, Ryan F. Richholt, Stephen D. Mastrian, Cody Babb, Audrey A. Ozols, Laurie J. Goodman, Gargi D. Basu, Thomas Royce

Published Apr 7, 2021 · Vol. 12, No. 8 · pp. 726-739

Keywords: comprehensive genomic profiling, whole exome sequencing, RNA sequencing, precision medicine, pan-cancer

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Matthew A.M. Devall, Graham Casey

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 767-782

Keywords: colorectal cancer, single-cell deconvolution, microsatellite instability, RNA-sequencing, enteroendocrine

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Jared Mamrot, Nathan E. Hall, Robyn A. Lindley

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 845-858

Keywords: innate immunity, biomarker, mutagenesis, oncogenesis, cancer progression

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Karamat Mohammad, Vladimir I. Titorenko

Published Mar 19, 2021 · Vol. 12, No. 7 · pp. 608-625

Keywords: cellular aging, geroprotectors, caloric restriction, metabolism, methionine

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

Balraj Singh, Vanessa N. Sarli, Anthony Lucci

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 626-637

Keywords: resistant TNBC, minimal residual disease, intratumor heterogeneity, breast cancer relapse, metastasis prevention

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Dorota Koczkodaj, Justyna Muzyka-Kasietczuk, Sylwia Chocholska, Monika Podhorecka

Published Mar 5, 2021 · Vol. 12, No. 7 · pp. 708-718

Keywords: isochromosome 17q, karyotype, FISH, hematologic malignancies, prognosis

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Jared A. Sninsky, Kumar S. Bishnupuri, Iván González, Nikolaos A. Trikalinos, Ling Chen, Brian K. Dieckgraefe

Published Feb 8, 2021 · Vol. 12, No. 4 · pp. 278-291

Keywords: Reg4, CD44, CD44ICD, colorectal cancer

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Ralf Bergmann, Constance Chollet, Sylvia Els-Heindl, Martin Ullrich, Nicole Berndt, Jens Pietzsch, Domokos Máthé, Michael Bachmann, Annette G. Beck-Sickinger

Published Feb 7, 2021 · Vol. 12, No. 5 · pp. 450-474

Keywords: cancer, prostate cancer, growth hormone secretagogue receptor (GHS-R), small animal imaging, copper-64

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Marieke Stegink, Marion T.J. van den Bosch, Mir Farshid Alemdehy, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot

Published Feb 7, 2021 · Vol. 12, No. 5 · pp. 422-439

Keywords: miR-193a-3p, microRNA mimic, microRNA delivery in vivo, pleiotropic mechanism of microRNA,

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

Julie Guibon, Pierre-Emmanuel Sugier, Om Kulkarni, Mojgan Karimi, Delphine Bacq-Daian, Céline Besse, Anne Boland, Elisabeth Adjadj, Frédérique Rachédi, Carole Rubino, Constance Xhaard, Claire Mulot, Pierre Laurent-Puig, Anne-Valérie Guizard, Claire Schvartz, Rosa Maria Ortiz, Yan Ren, Evgenia Ostroumova, Jean-François Deleuze, Marie-Christine Boutron-Ruault, Ausrele Kesminiene, Florent De Vathaire, Pascal Guénel, Fabienne Lesueur, Thérèse Truong

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 493-506

Keywords: thyroid cancer, cancer genetics, case-control study, fine-mapping study, single nucleotide polymorphism

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Taghi Manshouri, Ivo Veletic, Alessandra Ferrajoli, Prithviraj Bose, Phillip Thompson, Nitin Jain, Srdan Verstovsek, William Wierda, Michael J. Keating, Zeev Estrov

Published Jan 30, 2021 · Vol. 12, No. 5 · pp. 401-411

Keywords: CLL, STAT3, GLI1, apoptosis, transcription

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Rolando Pérez-Lorenzo, Stephanie O. Erjavec, Angela M. Christiano, Raphael Clynes

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 66-80

Keywords: anti-tumor antibodies, targeted therapy, immunotherapy, combination therapies, melanoma

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Juyeon Ko, April N. Meyer, Martin Haas, Daniel J. Donoghue

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 22-36

Keywords: metastatic castrate-resistant prostate cancer, spheroid culture, tyrosine kinase inhibitor

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Krastan B. Blagoev, Roumen Iordanov, Mengxi Zhou, Tito Fojo, Susan E. Bates

Published Dec 19, 2020 · Vol. 12, No. 1 · pp. 15-21

Keywords: drug resistance, metastatic prostate cancer, exponential growth, tumor kinetics, cancer stem cells

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana, Reinhard Dummer

Published Dec 18, 2020 · Vol. 12, No. 2 · pp. 125-130

Keywords: spitzoid nevi, melanocytic lesion, dermatopathology, pediatric dermatology, diagnostic algorithm

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Alexandros Diamantis, Athina A. Samara, Dimitrios Symeonidis, Ioannis Baloyiannis, Dionysia Vasdeki, Maria Tolia, Georgios Volakakis, Georgios Mavrovounis, Konstantinos Tepetes

Published Dec 17, 2020 · Vol. 11, No. 52 · pp. 4813-4821

Keywords: gastrointestinal stromal tumor, mesenchymal tumors, synchronous malignancies

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

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Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy Research Paper

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra® Research Paper

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

Prognostic significance of isochromosome 17q in hematologic malignancies Case Report

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Gastrointestinal stromal tumors (GISTs) and synchronous intra-abdominal malignancies: case series of a single institution’s experience Research Paper

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra^® Research Paper