The Oncosearch | Oncotarget

Phase 3 LILAC study sets standard for clinical evaluation of oncology biosimilars Editorial

Hans-Christian Kolberg, Gunter von Minckwitz, Vladimir Hanes

Published Dec 21, 2018 · Vol. 10, No. 1 · pp. 8-9

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition Priority Research Paper

Priya K. Gopalan, Andres Gordillo Villegas, Chunxia Cao, Mary Pinder-Schenck, Alberto Chiappori, Wei Hou, Maria Zajac-Kaye, Alison M. Ivey, Frederic J. Kaye

Published Dec 21, 2018 · Vol. 9, No. 100 · pp. 37352-37366

Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma Research Paper

Nicholas M. Szigetvari, Deepika Dhawan, JosÃ© A. Ramos-Vara, Christopher P. Leamon, Patrick J. Klein, A. Audrey Ruple, Hock Gan Heng, Michael R. Pugh, Satish Rao, Iontcho R. Vlahov, Pierre L. Deshuillers, Philip S. Low, Lindsey M. Fourez, Ashleigh M. Cournoyer, Deborah W. Knapp

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 37042-37053

Insight into the PTEN â€“ p85Î± interaction and lipid binding properties of the p85Î± BH domain Research Paper

Jeremy D.S. Marshall, Paul Mellor, Xuan Ruan, Dielle E. Whitecross, Stanley A. Moore, Deborah H. Anderson

Published Dec 11, 2018 · Vol. 9, No. 97 · pp. 36975-36992

Diagnostic performance of Gd-EOB-DTPA-enhanced MRI for evaluation of liver dysfunction: a multivariable analysis of 3T MRI sequences Research Paper

Niklas Verloh, Kirsten Utpatel, Florian Zeman, Claudia Fellner, Hans J. Schlitt, Martina MÃ¼ller, Christian Stroszczynski, Matthias Evert, Philipp Wiggermann, Michael Haimerl

Published Nov 20, 2018 · Vol. 9, No. 91 · pp. 36371-36378

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis Research Paper

Wei Sha, Yanfei Zhou, Zhi-Qiang Ling, Guiqin Xie, Xiaowu Pang, Paul Wang, Xinbin Gu

Published Nov 20, 2018 · Vol. 9, No. 91 · pp. 36331-36343

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study Research Paper

BegoÃ±a Martin-Castillo, Sonia Pernas, Joan Dorca, Isabel Ãlvarez, Susana MartÃnez, Jose Manuel PÃ©rez-Garcia, Norberto Batista-LÃ³pez, CÃ©sar A. RodrÃguez-SÃ¡nchez, Kepa Amillano, Severina DomÃnguez, Maria Luque, Agostina Stradella, Idoia Morilla, Gemma ViÃ±as, Javier CortÃ©s, Elisabet CuyÃ s, Sara Verdura, Ãlvaro FernÃ¡ndez-Ochoa, Salvador FernÃ¡ndez-Arroyo, Antonio Segura-Carretero, Jorge Joven, Elsa PÃ©rez, Neus Bosch, Margarita Garcia, Eugeni LÃ³pez-Bonet, Samiha Saidani, Maria BuxÃ³, Javier A. Menendez

Published Nov 2, 2018 · Vol. 9, No. 86 · pp. 35687-35704

A phase I pilot study evaluating the beneficial effects of black raspberries in patients with Barrettâ€™s esophagus Clinical Research Papers

Laura A. Kresty, John J. Fromkes, Wendy L. Frankel, Cynthia D. Hammond, Navindra P. Seeram, Maureen Baird, Gary D. Stoner

Published Oct 19, 2018 · Vol. 9, No. 82 · pp. 35356-35372

The transgenic expression of the β-subunit of human chorionic gonadotropin influences the growth of implanted tumor cells Research Paper

Poonam Singh, Moumita Sarkar, Usha Agrawal, Ilpo Huhtaniemi, Rahul Pal

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34670-34680

Does afatinib plus bevacizumab combination therapy induce positive conversion of T790M in previously-negative patients? Research Paper

Akito Hata, Nobuyuki Katakami, Reiko Kaji, Toshihide Yokoyama, Toshihiko Kaneda, Motohiro Tamiya, Takako Inoue, Hiromi Kimura, Yukihiro Yano, Daisuke Tamura, Satoshi Morita, Shunichi Negoro

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34765-34771

Everolimus (EVE) and exemestane (EXE) in patients with advanced breast cancer aged ≥ 65 years: new lessons for clinical practice from the EVA study Research Paper

Marina Cazzaniga, Claudio Verusio, Mariangela Ciccarese, Alberto Fumagalli, Donata Sartori, Maria Rosaria Valerio, Mario Airoldi, Gabriella Moretti, Corrado Ficorella, Valentina Arcangeli, Lucrezia Diodati, Alberto Zambelli, Antonio Febbraro, Daniele Generali, Mirco Pistelli, Ornella Garrone, Antonino Musolino, Patrizia Vici, Michela Maur, Lucia Mentuccia, Nicla La Verde, Giulia Bianchi, Salvatore Artale, Livio Blasi, Matilde Piezzo, Francesco Atzori, Anna Turletti, Chiara Benedetto, Maria Concetta Cursano, Alessandra Fabi, Vittorio Gebbia, Alessio Schirone, Raffaella Palumbo, Antonella Ferzi, Antonio Frassoldati, Claudio Scavelli, Luca Clivio, Valter Torri on behalf of The EVA Study Group

Published Oct 2, 2018 · Vol. 9, No. 61 · pp. 31877-31887

Surrogate endpoints in advanced sarcoma trials: a meta-analysis Meta-Analysis

Marion Savina, Saskia LitiÃ¨re, Antoine Italiano, Tomasz Burzykowski, Franck Bonnetain, Sophie Gourgou, Virginie Rondeau, Jean-Yves Blay, Sophie Cousin, Florence Duffaud, Hans Gelderblom, Alessandro Gronchi, Ian Judson, Axel Le Cesne, Paul Lorigan, Joan Maurel, Winette van der Graaf, Jaap Verweij, Simone Mathoulin-PÃ©lissier, Carine Bellera

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34617-34627

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2 Research Paper

Li Wang, Yujuan Zhang, Kangdong Liu, Hanyong Chen, Ran Yang, Xiaoli Ma, Hong-Gyum Kim, Ann M. Bode, Dong Joon Kim, Zigang Dong

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34200-34212

Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma Research Paper

Yoshinobu Shigekawa, Shinya Hayami, Masaki Ueno, Atsushi Miyamoto, Norihiko Suzaki, Manabu Kawai, Seiko Hirono, Ken-ichi Okada, Ryuji Hamamoto, Hiroki Yamaue

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34320-34335

Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents Research Paper

Emma J. Jordan, James Spicer, Debashis Sarker

Published Sep 21, 2018 · Vol. 9, No. 74 · pp. 33961-33971

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper

Francesca De Felice, Giancarlo Dâ€™Ambrosio, Daniela Musio, Franco Iafrate, Ilaria Benevento, Marco Marzo, Marialaura Mancini, Federica Urbano, Marcella Iannitti, Francesco Marampon, Nadia Bulzonetti, Enrico Cortesi, Vincenzo Tombolini

Published Sep 14, 2018 · Vol. 9, No. 72 · pp. 33702-33709

Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells Research Paper

Tasaduq H. Wani, Sreeraj Surendran, Vishnu S. Mishra, Jaya Chaturvedi, Goutam Chowdhury, Anindita Chakrabarty

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33589-33600

Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme Research Paper

Ramon Martinez-Olivera, Angeliki Datsi, Maren Stallkamp, Manfred KÃ¶ller, Isabelle Kohtz, Bogdan Pintea, Konstantinos Gousias

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33471-33481

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Yudong Wang, Zhijie Wang, Sarina Piha-Paul, Filip Janku, Vivek Subbiah, Naiyi Shi, Kenneth Hess, Russell Broaddus, Baoen Shan, Aung Naing, David Hong, Apostolia M. Tsimberidou, Daniel Karp, Charles Lu, Vali Papadimitrakopoulou, John Heymach, Funda Meric-Bernstam, Siqing Fu

Published Sep 7, 2018 · Vol. 9, No. 70 · pp. 33258-33270

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper

Shengwen Calvin Li, Andres Stucky, Xuelian Chen, Mustafa H. Kabeer, William G. Loudon, Ashley S. Plant, Lilibeth Torno, Chaitali S. Nangia, Jin Cai, Gang Zhang, Jiang F. Zhong

Published Sep 7, 2018 · Vol. 9, No. 70 · pp. 33290-33301

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Phase 3 LILAC study sets standard for clinical evaluation of oncology biosimilars Editorial

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition Priority Research Paper

Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma Research Paper

Insight into the PTEN â€“ p85Î± interaction and lipid binding properties of the p85Î± BH domain Research Paper

Diagnostic performance of Gd-EOB-DTPA-enhanced MRI for evaluation of liver dysfunction: a multivariable analysis of 3T MRI sequences Research Paper

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis Research Paper

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study Research Paper

A phase I pilot study evaluating the beneficial effects of black raspberries in patients with Barrettâ€™s esophagus Clinical Research Papers

The transgenic expression of the β-subunit of human chorionic gonadotropin influences the growth of implanted tumor cells Research Paper

Does afatinib plus bevacizumab combination therapy induce positive conversion of T790M in previously-negative patients? Research Paper

Everolimus (EVE) and exemestane (EXE) in patients with advanced breast cancer aged ≥ 65 years: new lessons for clinical practice from the EVA study Research Paper

Surrogate endpoints in advanced sarcoma trials: a meta-analysis Meta-Analysis

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2 Research Paper

Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma Research Paper

Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents Research Paper

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper

Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells Research Paper

Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme Research Paper

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Phase 3 LILAC study sets standard for clinical evaluation of oncology biosimilars Editorial

CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition Priority Research Paper

Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma Research Paper

Insight into the PTEN â€“ p85Î± interaction and lipid binding properties of the p85Î± BH domain Research Paper

Diagnostic performance of Gd-EOB-DTPA-enhanced MRI for evaluation of liver dysfunction: a multivariable analysis of 3T MRI sequences Research Paper

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis Research Paper

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study Research Paper

A phase I pilot study evaluating the beneficial effects of black raspberries in patients with Barrettâ€™s esophagus Clinical Research Papers

The transgenic expression of the β-subunit of human chorionic gonadotropin influences the growth of implanted tumor cells Research Paper

Does afatinib plus bevacizumab combination therapy induce positive conversion of T790M in previously-negative patients? Research Paper

Everolimus (EVE) and exemestane (EXE) in patients with advanced breast cancer aged ≥ 65 years: new lessons for clinical practice from the EVA study Research Paper

Surrogate endpoints in advanced sarcoma trials: a meta-analysis Meta-Analysis

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2 Research Paper

Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma Research Paper

Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents Research Paper

Induction chemotherapy followed by neoadjuvant chemoradiotherapy and surgery in locally advanced rectal cancer: preliminary results of a phase II study Research Paper

Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells Research Paper

Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme Research Paper

Outcome analysis of Phase I trial patients with metastatic KRAS and/or TP53 mutant non-small cell lung cancer Research Paper

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper