The Oncosearch | Oncotarget

Biomarkers of reactive resistance and early disease progression during chemotherapy plus bevacizumab treatment for colorectal carcinoma Research Paper

Hidetoshi Hayashi, Tokuzo Arao, Kazuko Matsumoto, Hideharu Kimura Kimura, Yosuke Togashi, Yoshinori Hirashima, Yosuke Horita, Satoru Iwasa, Natsuko Tsuda Okita, Yoshitaka Honma, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Yasuhiro Shimada, Kazuhiko Nakagawa, Kazuto Nishio, Yasuhide Yamada

Published Mar 22, 2014 · Vol. 5, No. 9 · pp. 2588-2595

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Ken Maes, Eva De Smedt, Miguel Lemaire, Hendrik De Raeve, Eline Menu, Els Van Valckenborgh, Steve McClue, Karin Vanderkerken, Elke De Bruyne

Published Mar 22, 2014 · Vol. 5, No. 10 · pp. 3115-3129

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus Research Paper

Sarina A. Piha-Paul, Jennifer J. Wheler, Siqing Fu, Charles Levenback, Karen Lu, Gerald S. Falchook, Aung Naing, David S. Hong, Apostolia M. Tsimberidou, Razelle Kurzrock

Published Mar 20, 2014 · Vol. 5, No. 7 · pp. 1846-1855

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

Denis L. Fontes Jardim, Debora de Melo Gagliato, Gerald S. Falchook, Filip Janku, Ralph Zinner, Jennifer J. Wheler, Vivek Subbiah, Sarina A. Piha-Paul, Siqing Fu, Mariela Blum Murphy, Jaffer Ajani, Chad Tang, Kenneth Hess, Stanley R. Hamilton, Sinchita Roy-Chowdhuri, Razelle Kurzrock, Funda Meric-Bernstam, David S. Hong

Published Mar 16, 2014 · Vol. 5, No. 7 · pp. 1837-1845

miR-34: from bench to bedside Review

Massimiliano Agostini, Richard A. Knight

Published Mar 15, 2014 · Vol. 5, No. 4 · pp. 872-881

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Jennifer J. Wheler, Stacy L. Moulder, Aung Naing, Filip Janku, Sarina A. Piha-Paul, Gerald S. Falchook, Ralph Zinner, Apostolia M. Tsimberidou, Siqing Fu, David S. Hong, Johnique T. Atkins, Roman Yelensky, Philip J. Stephens, Razelle Kurzrock

Published Mar 14, 2014 · Vol. 5, No. 10 · pp. 3029-3038

Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate Research Paper

Jayabal Panneerselvam, Anna Pickering, Bing Han, Liantao Li, Junnian Zheng, Jun Zhang, Yanbin Zhang, Peiwen Fei

Published Mar 13, 2014 · Vol. 5, No. 5 · pp. 1326-1337

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Joshua Armenia, Linda Fabris, Francesca Lovat, Stefania Berton, Ilenia Segatto, Sara Dâ€™Andrea, Cristina Ivan, Luciano Cascione, George A. Calin, Carlo M. Croce, Alfonso Colombatti, Andrea Vecchione, Barbara Belletti, Gustavo Baldassarre

Published Mar 4, 2014 · Vol. 5, No. 5 · pp. 1185-1197

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Shigeru Kawabata, Chun-Te Chiang, Junji Tsurutani, Hideaki Shiga, Matthew L. Arwood, Takefumi Komiya, Joell J. Gills, Regan M. Memmott, Phillip A. Dennis

Published Feb 16, 2014 · Vol. 5, No. 4 · pp. 1062-1070

Keywords: Rapamycin, Pemetrexed, Drug synergy, mTOR, Thymidylate Synthase, Lung Cancer

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Arnau Montraveta, Silvia Xargay-Torrent, MÃ³nica LÃ³pez-Guerra, Laia Rosich, Patricia PÃ©rez-GalÃ¡n, Itziar Salaverria, Silvia BeÃ, Susana G. Kalko, MercÃ¨ de Frias, Clara CampÃ s, GaÃ«l RouÃ©, Dolors Colomer

Published Jan 25, 2014 · Vol. 5, No. 3 · pp. 726-739

Keywords: Acadesine, rituximab, mantle cell lymphoma, xenograft mouse model

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

Enrica Borsi, Giulia Perrone, Carolina Terragna, Marina Martello, Angela F Dico, Giancarlo Solaini, Alessandra Baracca, Gianluca Sgarbi, Gianandrea Pasquinelli, Sabrina Valente, Elena Zamagni, Paola Tacchetti, Giovanni Martinelli, Michele Cavo

Published Jan 23, 2014 · Vol. 5, No. 7 · pp. 1779-1792

Keywords: HIF-1Î±, Multiple Myeloma, Cell cycle, Mitochondria, Warburg effect

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

Catherine A. Vaughan, Swati P. Deb, Sumitra Deb, Brad Windle

Published Jan 2, 2014 · Vol. 5, No. 2 · pp. 417-427

Keywords: mutant p53, ChIP-Seq, ETS1, bi-directional promoter

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

Rebecca Dunbar Schroeder, Laura S. Angelo, Razelle Kurzrock

Published Dec 17, 2013 · Vol. 5, No. 1 · pp. 67-77

Keywords: NF2, Nuerofibromatosis 2, Cancer, Mutations

mTOR pathway in colorectal cancer: an update Review

Maria Giovanna Francipane, Eric Lagasse

Published Dec 5, 2013 · Vol. 5, No. 1 · pp. 49-66

Keywords: mTOR, colorectal cancer, cancer stem-like cells, personalized medicine

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

Vivek Subbiah, Robert E. Brown, Mary F. McGuire, Jamie Buryanek, Filip Janku, Anas Younes, David Hong

Published Nov 19, 2013 · Vol. 5, No. 1 · pp. 95-102

Keywords: Hodgkin's lymphoma, mTOR, HDAC, Sirolimus, Vorinostat, Targeted therapy

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Xiaoping Wu, Huixian Huang, Cong Wang, Shaoqiang Lin, Yadong Huang, Yi Wang, Guang Liang, Qiuxia Yan, Jian Xiao, Jianzhang Wu, Yongguang Yang, Xiaokun Li

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1819-1828

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Duane H. Hamilton, Mary T. Litzinger, Alessandra Jales, Bruce Huang, Romaine I. Fernando, James W. Hodge, Andressa Ardiani, David Apelian, Jeffrey Schlom, Claudia Palena

Published Sep 26, 2013 · Vol. 4, No. 10 · pp. 1777-1790

Keywords: epithelial-mesenchymal transition, brachyury, T-box transcription factor, cancer vaccine, T-cell immunotherapy

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper

Jing Liu, Zhijie Xiao, Sunny Kit-Man Wong, Vicky Pui-Chi Tin, Ka-Yan Ho, Junwen Wang, Mai-Har Sham, Maria Pik Wong

Published Aug 30, 2013 · Vol. 4, No. 10 · pp. 1698-1711

Keywords: lung cancer, tumor initiating cell, aldehyde dehydrogenase, CD44, drug resistance

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Biomarkers of reactive resistance and early disease progression during chemotherapy plus bevacizumab treatment for colorectal carcinoma Research Paper

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus Research Paper

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

miR-34: from bench to bedside Review

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate Research Paper

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

mTOR pathway in colorectal cancer: an update Review

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Biomarkers of reactive resistance and early disease progression during chemotherapy plus bevacizumab treatment for colorectal carcinoma Research Paper

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma Research Paper

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus Research Paper

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

miR-34: from bench to bedside Review

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate Research Paper

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner Priority Research Paper

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites Research Paper

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

mTOR pathway in colorectal cancer: an update Review

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDHhi CD44hi tumor initiating cells Research Paper

Lung cancer tumorigenicity and drug resistance are maintained through ALDH^hi CD44^hi tumor initiating cells Research Paper