The Oncosearch | Oncotarget

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

Chuan Bian Lim, Cecilia M. PrÃªle, Svetlana Baltic, Peter G. Arthur, Jenette Creaney, D. Neil Watkins, Philip J. Thompson, Steven E. Mutsaers

Published Jan 3, 2015 · Vol. 6, No. 3 · pp. 1519-1530

Keywords: Apoptosis, mesothelioma, GANT61, Hedgehog, mitochondria, reactive oxygen species

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

Sandra Liekens, Sam Noppen, Sofie Gijsbers, Rebecca Sienaert, Roberto Ronca, Chiara Tobia, Marco Presta

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4633-4648

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Elizabeth J. McConnell, Bharat Devapatla, Kavitha Yaddanapudi, Keith R. Davis

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4649-4662

Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

Jiang-Jiang Qin, Wei Wang, Sukesh Voruganti, Hui Wang, Wei-Dong Zhang, Ruiwen Zhang

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2623-2640

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Wafa Hassen, Alboukadel Kassambara, Thierry Reme, Surinder Sahota, Anja Seckinger, Laure Vincent, Guillaume Cartron, JÃ©rÃ´me Moreaux, Dirk Hose, Bernard Klein

Published Dec 26, 2014 · Vol. 6, No. 8 · pp. 6431-6447

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

Jonathan Vosper, Alessia Masuccio, Michael Kullmann, Christian Ploner, Stephan Geley, Ludger Hengst

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2889-2902

MYC is a critical target of FBXW7 Research Paper

Mai Sato, Ruth Rodriguez-Barrueco, Jiyang Yu, Catherine Do, Jose M. Silva, Jean Gautier

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3292-3305

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

Carmen Ruggiero, Giorgia Fragassi, Mauro Grossi, Benedetta Picciani, Rosaria Di Martino, Mirco Capitani, Roberto Buccione, Alberto Luini, Michele Sallese

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3375-3393

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, Guojun Zhang

Published Dec 11, 2014 · Vol. 6, No. 2 · pp. 1020-1030

Keywords: CXCR4, triple-negative breast cancer, cisplatin, chemosensitivity, apoptosis

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

Salvatore Delogu, Chunmei Wang, Antonio Cigliano, Kirsten Utpatel, Marcella Sini, Thomas Longerich, Nina Waldburger, Kai Breuhahn, Lijie Jiang, Silvia Ribback, Frank Dombrowski, Matthias Evert, Xin Chen, Diego F. Calvisi

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2222-2234

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Soo Jung Kim, Kyung Hee Jung, Hong Hua Yan, Mi Kwon Son, Zhenghuan Fang, Ye-Lim Ryu, Hyunseung Lee, Joo Han Lim, Jun-Kyu Suh, JinHee Kim, Soyoung Lee, Sungwoo Hong, Soon-Sun Hong

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1507-1518

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Francesca Grasso, Vitalba Ruggieri, Gabriele De Luca, Paola Leopardi, Maria Teresa Mancuso, Ida Casorelli, Pietro Pichierri, Peter Karran, Margherita Bignami

Published Dec 2, 2014 · Vol. 6, No. 10 · pp. 7481-7492

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Itay Pickholtz, Shira Saadyan, Gilmor I. Keshet, Victor S. Wang, Rachel Cohen, Peter Bouwman, Jos Jonkers, Stephen W. Byers, Moshe Z. Papa, Ronit I. Yarden

Published Nov 26, 2014 · Vol. 5, No. 23 · pp. 11827-11846

Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia Research Paper

Minran Zhou, Jiping Zeng, Xiaoming Wang, Xiangyu Wang, Tao Huang, Yue Fu, Ting Sun, Jihui Jia, Chunyan Chen

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1249-1261

Androgen receptors beyond prostate cancer: an old marker as a new target Review

Javier Munoz, Jennifer J. Wheler, Razelle Kurzrock

Published Nov 15, 2014 · Vol. 6, No. 2 · pp. 592-603

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition Priority Research Paper

Rebecca Lamb, Hannah Harrison, James Hulit, Duncan L. Smith, Michael P. Lisanti, Federica Sotgia

Published Nov 15, 2014 · Vol. 5, No. 22 · pp. 11029-11037

Axl as a mediator of cellular growth and survival Review

Haley Axelrod, Kenneth J. Pienta

Published Nov 11, 2014 · Vol. 5, No. 19 · pp. 8818-8852

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1 Research Paper

Arun Bhardwaj, Sanjeev K. Srivastava, Seema Singh, Sumit Arora, Nikhil Tyagi, Joel Andrews, Steven McClellan, James E. Carter, Ajay P. Singh

Published Nov 11, 2014 · Vol. 5, No. 22 · pp. 11490-11500

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Gerald S. Falchook, Jennifer J. Wheler, Aung Naing, Edward F. Jackson, Filip Janku, David Hong, Chaan S. Ng, Nizar M. Tannir, Kristie N. Lawhorn, Mei Huang, Laura S. Angelo, Deeksha Vishwamitra, Kenneth Hess, Adrienne N. Howard, Kristin L. Parkhurst, Hesham M. Amin, Razelle Kurzrock

Published Nov 8, 2014 · Vol. 5, No. 21 · pp. 10280-10292

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer Priority Research Paper

Catherine Burkhart, Daria Fleyshman, Rachael Kohrn, Mairead Commane, Jennifer Garrigan, Vadim Kurbatov, Ilya Toshkov, Rajesh Ramachandran, Laura Martello, Katerina V. Gurova

Published Nov 6, 2014 · Vol. 5, No. 22 · pp. 11038-11053

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Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

MYC is a critical target of FBXW7 Research Paper

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia Research Paper

Androgen receptors beyond prostate cancer: an old marker as a new target Review

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition Priority Research Paper

Axl as a mediator of cellular growth and survival Review

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1 Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation Priority Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

MYC is a critical target of FBXW7 Research Paper

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia Research Paper

Androgen receptors beyond prostate cancer: an old marker as a new target Review

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition Priority Research Paper

Axl as a mediator of cellular growth and survival Review

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1 Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer Priority Research Paper