The Oncosearch | Oncotarget

The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines Research Paper

Huimin Bai, Haixia Li, Weihua Li, Ting Gui, Jiaxin Yang, Dongyan Cao, Keng Shen

Published Jul 14, 2015 · Vol. 6, No. 28 · pp. 25520-25532

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Andrew K. Kwegyir-Afful, Senthilmurugan Ramalingam, Puranik Purushottamachar, Vidya P. Ramamurthy, Vincent C. O. Njar

Published Jul 14, 2015 · Vol. 6, No. 29 · pp. 27440-27460

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

Anil Belur Nagaraj, Peronne Joseph, Olga Kovalenko, Sareena Singh, Amy Armstrong, Raymond Redline, Kimberly Resnick, Kristine Zanotti, Steven Waggoner, Analisa DiFeo

Published Jun 29, 2015 · Vol. 6, No. 27 · pp. 23720-23734

Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibition Research Paper

Lisa Lange, Peter Hemmerich, Birgit SpÃ¤nkuch

Published Jun 26, 2015 · Vol. 6, No. 28 · pp. 25801-25814

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Ishwaria M. Subbiah, Gerald S. Falchook, Ahmed O. Kaseb, Kenneth R. Hess, Apostolia M. Tsimberidou, Siqing Fu, Vivek Subbiah, David S. Hong, Aung Naing, Sarina A. Piha-Paul, Owais Akmal, Filip Janku, Razelle Kurzrock

Published Jun 23, 2015 · Vol. 6, No. 29 · pp. 28453-28462

Long-term results of a randomized phase III trial of TPF induction chemotherapy followed by surgery and radiation in locally advanced oral squamous cell carcinoma Clinical Research Papers

Lai-ping Zhong, Chen-ping Zhang, Guo-xin Ren, Wei Guo, William N. William Jr, Christopher S. Hong, Jian Sun, Han-guang Zhu, Wen-yong Tu, Jiang Li, Yi-li Cai, Qiu-ming Yin, Li-zhen Wang, Zhong-he Wang, Yong-jie Hu, Tong Ji, Wen-jun Yang, Wei-min Ye, Jun Li, Yue He, Yan-an Wang, Li-qun Xu, Zhengping Zhuang, J. Jack Lee, Jeffrey N. Myers, Zhi-yuan Zhang

Published Jun 19, 2015 · Vol. 6, No. 21 · pp. 18707-18714

TRIM66 overexpresssion contributes to osteosarcoma carcinogenesis and indicates poor survival outcome Research Paper

Yu Chen, Yongfei Guo, Haisong Yang, Guodong Shi, Guohua Xu, Jiangang Shi, Na Yin, Deyu Chen

Published Jun 17, 2015 · Vol. 6, No. 27 · pp. 23708-23719

The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells Research Paper

Ying Gao, Renbin Huang, Yixuan Gong, Hyo Sim Park, Qingwei Wen, Nadin Marwan Almosnid, Uma D. Chippada-Venkata, Najlaa Abdulrhman Hosain, Eric Vick, Anthony Farone, Elliot Altman

Published Jun 15, 2015 · Vol. 6, No. 27 · pp. 24304-24319

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy Priority Research Paper

Rebecca Lamb, Marco Fiorillo, Amy Chadwick, Bela Ozsvari, Kimberly J. Reeves, Duncan L. Smith, Robert B. Clarke, Sacha J. Howell, Anna Rita Cappello, Ubaldo E. Martinez-Outschoorn, Maria Peiris-PagÃ¨s, Federica Sotgia, Michael P. Lisanti

Published Jun 13, 2015 · Vol. 6, No. 16 · pp. 14005-14025

Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1 Research Paper

Shuai Lu, Helga-Paula TÃ¶rÃ¶k, Eike Gallmeier, Frank T. Kolligs, Antonia Rizzani, Sabrina Arena, Burkhard GÃ¶ke, Alexander L. Gerbes, Enrico N. De Toni

Published Jun 10, 2015 · Vol. 6, No. 26 · pp. 22167-22178

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

Christophe Deben, An Wouters, Ken Op de Beeck, Jolien van Den Bossche, Julie Jacobs, Karen Zwaenepoel, Marc Peeters, Jan Van Meerbeeck, Filip Lardon, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels

Published Jun 10, 2015 · Vol. 6, No. 26 · pp. 22666-22679

rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis Research Paper

Sandeep S. Negi, Patrick Brown

Published Jun 5, 2015 · Vol. 6, No. 20 · pp. 18094-18104

Efficacy and safety analysis of trastuzumab and paclitaxel based regimen plus carboplatin or epirubicin as neoadjuvant therapy for clinical stage II-III, HER2-positive breast cancer patients: a phase 2, open-label, multicenter, randomized trial Clinical Research Papers

Liang Huang, Sheng Chen, Wentao Yang, Binghe Xu, Tao Huang, Hongjian Yang, Hong Zheng, Yongsheng Wang, Erwei Song, Jin Zhang, Shude Cui, Da Pang, Lili Tang, Yutao Lei, Cuizhi Geng, Zhiming Shao

Published Jun 2, 2015 · Vol. 6, No. 21 · pp. 18683-18692

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

Michal Podrazil, Rudolf Horvath, Etienne Becht, Daniela Rozkova, Pavla Bilkova, Hana Hromadkova, Jana Kayserova, Katerina Vavrova, Jan Lastovicka, Petra Vrabcova, Katerina Kubackova, Zdenka Gasova, Ladislav Jarolim, Marek Babjuk, Radek Spisek, Jirina Bartunkova, Jitka Fucikova

Published May 29, 2015 · Vol. 6, No. 20 · pp. 18192-18205

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Mounia Guerram, Zhen-Zhou Jiang, Bashir Alsiddig Yousef, Aida Mejda Hamdi, Hozeifa Mohamed Hassan, Zi-Qiao Yuan, Hou-Wei Luo, Xiong Zhu, Lu-Yong Zhang

Published May 28, 2015 · Vol. 6, No. 26 · pp. 21865-21877

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Jia-Jie Chen, Nan Cai, Guan-Zhong Chen, Chang-Chang Jia, Dong-Bo Qiu, Cong Du, Wei Liu, Yang Yang, Zi-Jie Long, Qi Zhang

Published May 27, 2015 · Vol. 8, No. 11 · pp. 17593-17609

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns Research Paper

Ingrid Cifola, Marta Lionetti, Eva Pinatel, Katia Todoerti, Eleonora Mangano, Alessandro Pietrelli, Sonia Fabris, Laura Mosca, Vittorio Simeon, Maria Teresa Petrucci, Fortunato Morabito, Massimo Offidani, Francesco Di Raimondo, Antonietta Falcone, Tommaso Caravita, Cristina Battaglia, Gianluca De Bellis, Antonio Palumbo, Pellegrino Musto, Antonino Neri

Published May 25, 2015 · Vol. 6, No. 19 · pp. 17543-17558

PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21 Research Paper

Fei-Ran Gong, Meng-Yao Wu, Meng Shen, Qiaoming Zhi, Ze-Kuan Xu, Rong Wang, Wen-Jie Wang, Yang Zong, Zeng-Liang Li, Yadi Wu, Binhua P. Zhou, Kai Chen, Min Tao, Wei Li

Published May 25, 2015 · Vol. 6, No. 21 · pp. 18469-18483

Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells Research Paper

Lixia Wang, Xiantao Ye, Xingming Cai, Jingna Su, Renqiang Ma, Xuyuan Yin, Xiuxia Zhou, Huabin Li, Zhiwei Wang

Published May 23, 2015 · Vol. 6, No. 20 · pp. 18027-18037

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

Rute Loureiro, Silvia MagalhÃ£es-Novais, Katia A. Mesquita, Ines Baldeiras, Isabel S. Sousa, Ludgero C. Tavares, Ines A. Barbosa, Paulo J. Oliveira, Ignacio Vega-Naredo

Published May 20, 2015 · Vol. 6, No. 19 · pp. 17081-17096

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The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines Research Paper

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibition Research Paper

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Long-term results of a randomized phase III trial of TPF induction chemotherapy followed by surgery and radiation in locally advanced oral squamous cell carcinoma Clinical Research Papers

TRIM66 overexpresssion contributes to osteosarcoma carcinogenesis and indicates poor survival outcome Research Paper

The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells Research Paper

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy Priority Research Paper

Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1 Research Paper

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis Research Paper

Efficacy and safety analysis of trastuzumab and paclitaxel based regimen plus carboplatin or epirubicin as neoadjuvant therapy for clinical stage II-III, HER2-positive breast cancer patients: a phase 2, open-label, multicenter, randomized trial Clinical Research Papers

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns Research Paper

PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21 Research Paper

Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines Research Paper

Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo Research Paper

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibition Research Paper

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials Clinical Research Papers

Long-term results of a randomized phase III trial of TPF induction chemotherapy followed by surgery and radiation in locally advanced oral squamous cell carcinoma Clinical Research Papers

TRIM66 overexpresssion contributes to osteosarcoma carcinogenesis and indicates poor survival outcome Research Paper

The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells Research Paper

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy Priority Research Paper

Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1 Research Paper

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis Research Paper

Efficacy and safety analysis of trastuzumab and paclitaxel based regimen plus carboplatin or epirubicin as neoadjuvant therapy for clinical stage II-III, HER2-positive breast cancer patients: a phase 2, open-label, multicenter, randomized trial Clinical Research Papers

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer Clinical Research Papers

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns Research Paper

PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21 Research Paper

Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells Research Paper

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells Research Paper