The Oncosearch | Oncotarget

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype Research Paper

Verena Rohnalter, Katrin Roth, Florian Finkernagel, Till Adhikary, Julia Obert, Kristina Dorzweiler, Maike Bensberg, Sabine MÃ¼ller-BrÃ¼sselbach, Rolf MÃ¼ller

Published Oct 19, 2015 · Vol. 6, No. 37 · pp. 40005-40025

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

David S. Hong, Razelle Kurzrock, Gerald S. Falchook, Corina Andresen, Jennifer Kwak, Min Ren, Lucy Xu, Goldy C. George, Kevin B. Kim, Ly M. Nguyen, James P. Oâ€™Brien, John Nemunaitis

Published Oct 15, 2015 · Vol. 6, No. 40 · pp. 43127-43134

Arenobufagin intercalates with DNA leading to G₂ cell cycle arrest via ATM/ATR pathway Research Paper

Li-Juan Deng, Qun-Long Peng, Long-Hai Wang, Jun Xu, Jun-Shan Liu, Ying-Jie Li, Zhen-Jian Zhuo, Liang-Liang Bai, Li-Ping Hu, Wei-Min Chen, Wen-Cai Ye, Dong-Mei Zhang

Published Oct 13, 2015 · Vol. 6, No. 33 · pp. 34258-34275

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Sandeep S. Negi, Patrick Brown

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34846-34858

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

Yi-Hsien Hsieh, Shu-Ching Hsieh, Chien-Hsing Lee, Shun-Fa Yang, Chun-Wen Cheng, Meng-Ju Tang, Chia-Liang Lin, Chu-Liang Lin, Ruey-Hwang Chou

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34859-34874

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers

Hyo Song Kim, Sung-Moo Kim, Hyunki Kim, Kyoung-Ho Pyo, Jong-Mu Sun, Myung-Ju Ahn, Keunchil Park, Bhumsuk Keam, Nak-Jung Kwon, Hwan Jung Yun, Hoon-Gu Kim, Ik-Joo Chung, Jong Seok Lee, Kyung Hee Lee, Dae Joon Kim, Changâ€‘Geol Lee, Jin Hur, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Hye Ryun Kim, Yong Wha Moon, Yong Chan Lee, Joo Hang Kim, Soonmyung Paik, Byoung Chul Cho

Published Oct 9, 2015 · Vol. 6, No. 42 · pp. 44971-44984

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma Research Paper

Jonathan J. Lee, Martin Cook, Martin C. Mihm, Shuyun Xu, Qian Zhan, Thomas J. Wang, George F. Murphy, Christine G. Lian

Published Oct 9, 2015 · Vol. 6, No. 35 · pp. 37995-38004

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Diana Spiegelberg, Adrian Dascalu, Anja C. Mortensen, Andris Abramenkovs, Gamze Kuku, Marika Nestor, Bo StenerlÃ¶w

Published Oct 6, 2015 · Vol. 6, No. 34 · pp. 35652-35666

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Chun-Han Chen, Chia-Hwa Lee, Jing-Ping Liou, Che-Ming Teng, Shiow-Lin Pan

Published Oct 5, 2015 · Vol. 6, No. 34 · pp. 35991-36002

Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine Research Paper

Qi-Wei Jiang, Ke-Jun Cheng, Xiao-Long Mei, Jian-Ge Qiu, Wen-Ji Zhang, You-Qiu Xue, Wu-Ming Qin, Yang Yang, Di-Wei Zheng, Yao Chen, Meng-Ning Wei, Xu Zhang, Min Lv, Mei-Wan Chen, Xing Wei, Zhi Shi

Published Oct 5, 2015 · Vol. 6, No. 32 · pp. 32790-32804

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Valentina Restelli, Rosaria ChilÃ, Monica Lupi, Andrea Rinaldi, Ivo Kwee, Francesco Bertoni, Giovanna Damia, Laura Carrassa

Published Oct 2, 2015 · Vol. 6, No. 35 · pp. 37229-37240

Dietary NiCl₂ causes G₂/M cell cycle arrest in the broilerâ€™s kidney Research Paper

Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen, Jie Deng

Published Sep 30, 2015 · Vol. 6, No. 34 · pp. 35964-35977

Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors Priority Research Paper

Elisa Baldelli, Guido Bellezza, Eric B. Haura, Lucio CrinÃ³, W. Douglas Cress, Jianghong Deng, Vienna Ludovini, Angelo Sidoni, Matthew B. Schabath, Francesco Puma, Jacopo Vannucci, Annamaria Siggillino, Lance A. Liotta, Emanuel F. Petricoin III, Mariaelena Pierobon

Published Sep 30, 2015 · Vol. 6, No. 32 · pp. 32368-32379

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2 Research Paper

Atanasio Pandiella, Francisco MorÃs, Alberto OcaÃ±a, Luz-Elena NÃºÃ±ez, Juan C. Montero

Published Sep 30, 2015 · Vol. 6, No. 32 · pp. 32856-32867

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Yizhu Li, Priyanka Saini, Anusha Sriraman, Matthias Dobbelstein

Published Sep 29, 2015 · Vol. 6, No. 32 · pp. 32339-32352

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Da Eun Jeong, Hye Jin Song, Sharon Lim, Se Jeong Lee, Joung Eun Lim, Do-Hyun Nam, Kyeung Min Joo, Byong Chang Jeong, Seong Soo Jeon, Han Yong Choi, Hye Won Lee

Published Sep 28, 2015 · Vol. 6, No. 32 · pp. 33046-33064

Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9 Research Paper

Daren Low, Renuka Subramaniam, Li Lin, Tomoki Aomatsu, Atsushi Mizoguchi, Aylwin Ng, Arianna K. DeGruttola, Chun Geun Lee, Jack A. Elias, Akira Andoh, Mari Mino-Kenudson, Emiko Mizoguchi

Published Sep 28, 2015 · Vol. 6, No. 34 · pp. 36535-36550

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

Enrico Bronte, Giuseppe Bronte, Giuseppina Novo, Fabrizio Bronte, Maria Grazia Bavetta, Giuseppe Lo Re, Giuseppe Brancatelli, Viviana Bazan, Clara Natoli, Salvatore Novo, Antonio Russo

Published Sep 28, 2015 · Vol. 6, No. 34 · pp. 35589-35601

Multistep, effective drug distribution within solid tumors Research Paper

Amotz Shemi, Elina Zorde Khvalevsky, Rachel Malka Gabai, Abraham Domb, Yechezkel Barenholz

Published Sep 22, 2015 · Vol. 6, No. 37 · pp. 39564-39577

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

Meichun Xing, Xiaohui Wang, Timea Palmai-Pallag, Huahao Shen, Thomas Helleday, Ian D. Hickson, Songmin Ying

Published Sep 22, 2015 · Vol. 6, No. 35 · pp. 37638-37646

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A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype Research Paper

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

Arenobufagin intercalates with DNA leading to G₂ cell cycle arrest via ATM/ATR pathway Research Paper

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma Research Paper

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine Research Paper

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Dietary NiCl₂ causes G₂/M cell cycle arrest in the broilerâ€™s kidney Research Paper

Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors Priority Research Paper

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2 Research Paper

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9 Research Paper

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

Multistep, effective drug distribution within solid tumors Research Paper

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype Research Paper

Phase 1b study of lenvatinib (E7080) in combination with temozolomide for treatment of advanced melanoma Clinical Research Papers

Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway Research Paper

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells Research Paper

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma Clinical Research Papers

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma Research Paper

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells Research Paper

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Research Paper

Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine Research Paper

Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736 Research Paper

Dietary NiCl2 causes G2/M cell cycle arrest in the broilerâ€™s kidney Research Paper

Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors Priority Research Paper

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2 Research Paper

Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitors Priority Research Paper

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis Research Paper

Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9 Research Paper

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

Multistep, effective drug distribution within solid tumors Research Paper

Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response Research Paper

Arenobufagin intercalates with DNA leading to G₂ cell cycle arrest via ATM/ATR pathway Research Paper

Dietary NiCl₂ causes G₂/M cell cycle arrest in the broilerâ€™s kidney Research Paper