The Oncosearch | Oncotarget

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer Research Paper

MarÃa Dolores Cuenca-LÃ³pez, Gemma Serrano-Heras, Juan Carlos Montero, VerÃ³nica Corrales-SÃ¡nchez, MÃ³nica Gomez-Juarez, Maria JosÃ© GascÃ³n-Escribano, Jorge Carlos Morales, Veronique Voisin, Luz Elena NÃºÃ±ez, Francisco Moris, Gary D. Bader, Atanasio Pandiella, Alberto OcaÃ±a

Published Aug 12, 2015 · Vol. 6, No. 29 · pp. 27923-27937

miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1 Research Paper

Yonglei Liu, Yutong Wang, Xiangjun Sun, Chuanzhong Mei, Liying Wang, Zengxia Li, Xiliang Zha

Published Aug 12, 2015 · Vol. 7, No. 12 · pp. 13491-13501

Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway Research Paper

Wei Geng, Chung-Mau Lo, Kevin T.P. Ng, Chang-Chun Ling, Xiang Qi, Chang-Xian Li, Yuan Zhai, Xiao-Bing Liu, Yuen-Yuen Ma, Kwan Man

Published Aug 12, 2015 · Vol. 6, No. 29 · pp. 28042-28056

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

Jason M. Beckta, Seth M. Dever, Nisha Gnawali, Ashraf Khalil, Amrita Sule, Sarah E. Golding, Elizabeth Rosenberg, Aarthi Narayanan, Kylene Kehn-Hall, Bo Xu, Lawrence F. Povirk, Kristoffer Valerie

Published Aug 12, 2015 · Vol. 6, No. 29 · pp. 27674-27687

A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel Research Paper

Or Bida, Moriah Gidoni, Diana Ideses, Sol Efroni, Doron Ginsberg

Published Aug 11, 2015 · Vol. 6, No. 29 · pp. 27880-27890

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease Clinical Research Papers

Frits van Rhee, Corey Casper, Peter M. Voorhees, Luis E. Fayad, Helgi van de Velde, Jessica Vermeulen, Xiang Qin, Ming Qi, Brenda Tromp, Razelle Kurzrock

Published Aug 3, 2015 · Vol. 6, No. 30 · pp. 30408-30419

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy Clinical Research Papers

Sheng Zhang, Yao Zhu, Dingwei Ye

Published Jul 30, 2015 · Vol. 6, No. 31 · pp. 32212-32219

A long noncoding RNA AB073614 promotes tumorigenesis and predicts poor prognosis in ovarian cancer Research Paper

Zhongping Cheng, Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu

Published Jul 30, 2015 · Vol. 6, No. 28 · pp. 25381-25389

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

Mingming Liu, Zihao Qi, Bingzhi Liu, Yi Ren, Hanbin Li, Gong Yang, Qian Zhang

Published Jul 30, 2015 · Vol. 6, No. 28 · pp. 25281-25294

Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial Clinical Research Papers

Antonio Avallone, Biagio Pecori, Franco Bianco, Luigi Aloj, Fabiana Tatangelo, Carmela Romano, Vincenza Granata, Pietro Marone, Alessandra Leone, Gerardo Botti, Antonella Petrillo, Corradina CaracÃ², Vincenzo R. Iaffaioli, Paolo Muto, Giovanni Romano, Pasquale Comella, Alfredo Budillon, Paolo Delrio

Published Jul 30, 2015 · Vol. 6, No. 30 · pp. 30394-30407

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Filip Janku, Bart Claes, Helen J. Huang, Gerald S. Falchook, Benoit Devogelaere, Mark Kockx, Isabelle Vanden Bempt, Martin Reijans, Aung Naing, Siqing Fu, Sarina A. Piha-Paul, David S. Hong, Veronica R. Holley, Apostolia M. Tsimberidou, Vanda M. Stepanek, Sapna P. Patel, E. Scott Kopetz, Vivek Subbiah, Jennifer J. Wheler, Ralph G. Zinner, Daniel D. Karp, Rajyalakshmi Luthra, Sinchita Roy-Chowdhuri, Erwin Sablon, Funda Meric-Bernstam, Geert Maertens, Razelle Kurzrock

Published Jul 27, 2015 · Vol. 6, No. 29 · pp. 26886-26894

Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK Research Paper

Furong Xie, Xin Bao, Jingshuang Yu, Wantao Chen, Lizhen Wang, Zhiyuan Zhang, Qin Xu

Published Jul 27, 2015 · Vol. 6, No. 28 · pp. 25660-25676

Reduced rate of copy number aberrations in mucinous colorectal carcinoma Research Paper

Niek Hugen, Femke Simmer, Leonie J.M. Mekenkamp, Miriam Koopman, Evert van den Broek, Johannes H.W. de Wilt, Cornelis J.A. Punt, Bauke Ylstra, Gerrit A. Meijer, Iris D. Nagtegaal

Published Jul 25, 2015 · Vol. 6, No. 28 · pp. 25715-25725

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

Mike I. Walton, Paul D. Eve, Angela Hayes, Alan T. Henley, Melanie R. Valenti, Alexis K. De Haven Brandon, Gary Box, Kathy J. Boxall, Matthew Tall, Karen Swales, Thomas P. Matthews, Tatiana McHardy, Michael Lainchbury, James Osborne, Jill E. Hunter, Neil D. Perkins, G. Wynne Aherne, John C. Reader, Florence I. Raynaud, Suzanne A. Eccles, Ian Collins, Michelle D. Garrett

Published Jul 22, 2015 · Vol. 7, No. 3 · pp. 2329-2342

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy Clinical Research Papers

Chang-Jiang Qin, Xin-Ming Song, Zhi-Hui Chen, Xue-Qun Ren, Kai-Wu Xu, Hong Jing, Yu-Long He

Published Jul 22, 2015 · Vol. 6, No. 31 · pp. 32193-32204

Positive feedback loop of hepatoma-derived growth factor and Î²-catenin promotes carcinogenesis of colorectal cancer Research Paper

Jiayan Lian, Jianming Tang, Huijuan Shi, Hui Li, Tiantian Zhen, Wenlin Xie, Fenfen Zhang, Yang Yang, Anjia Han

Published Jul 22, 2015 · Vol. 6, No. 30 · pp. 29357-29374

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

Giorgia Montano, Karina Vidovic, Chiara Palladino, Elena Cesaro, Gaetano Sodaro, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Fabrizio Pane, Paola Izzo, Michela Grosso, Urban Gullberg, Paola Costanzo

Published Jul 22, 2015 · Vol. 6, No. 29 · pp. 28223-28237

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

Xiao Zhi, Wei Chen, Fei Xue, Chao Liang, Bryan Wei Chen, Yue Zhou, Liang Wen, Liqiang Hu, Jian Shen, Xueli Bai, Tingbo Liang

Published Jul 21, 2015 · Vol. 6, No. 28 · pp. 26230-26241

Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway Research Paper

Liping Wang, Zhufang Tian, Qi Yang, Heng Li, Haixia Guan, Bingyin Shi, Peng Hou, Meiju Ji

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 25917-25931

CCDC34 is up-regulated in bladder cancer and regulates bladder cancer cell proliferation, apoptosis and migration Research Paper

Yanqing Gong, Wei Qiu, Xianghui Ning, Xinyu Yang, Libo Liu, Zicheng Wang, Jian Lin, Xuesong Li, Yinglu Guo

Published Jul 16, 2015 · Vol. 6, No. 28 · pp. 25856-25867

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Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer Research Paper

miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1 Research Paper

Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway Research Paper

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel Research Paper

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease Clinical Research Papers

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy Clinical Research Papers

A long noncoding RNA AB073614 promotes tumorigenesis and predicts poor prognosis in ovarian cancer Research Paper

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial Clinical Research Papers

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK Research Paper

Reduced rate of copy number aberrations in mucinous colorectal carcinoma Research Paper

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy Clinical Research Papers

Positive feedback loop of hepatoma-derived growth factor and Î²-catenin promotes carcinogenesis of colorectal cancer Research Paper

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway Research Paper

CCDC34 is up-regulated in bladder cancer and regulates bladder cancer cell proliferation, apoptosis and migration Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer Research Paper

miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1 Research Paper

Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway Research Paper

Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining Research Paper

A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel Research Paper

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease Clinical Research Papers

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy Clinical Research Papers

A long noncoding RNA AB073614 promotes tumorigenesis and predicts poor prognosis in ovarian cancer Research Paper

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial Clinical Research Papers

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK Research Paper

Reduced rate of copy number aberrations in mucinous colorectal carcinoma Research Paper

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy Clinical Research Papers

Positive feedback loop of hepatoma-derived growth factor and Î²-catenin promotes carcinogenesis of colorectal cancer Research Paper

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

OSI-027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo Research Paper

Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway Research Paper

CCDC34 is up-regulated in bladder cancer and regulates bladder cancer cell proliferation, apoptosis and migration Research Paper