The Oncosearch | Oncotarget

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Pharavee Jaiprasart, Samrita Dogra, Deepika Neelakantan, Bharat Devapatla, Sukyung Woo

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 99-114

Keywords: anti-VEGF resistance, angiogenesis, bevacizumab, next-generation sequencing (NGS), apelin

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 6, 2020

Keywords: SHP2, FGFR, resistance, feedback activation

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Brandi L. Carofino, Kayla M. Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M. Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W. Wong, Vishal Koparde, Stuart H. Yuspa

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7251-7275

Keywords: in situ hybridization, single-cell RNA-sequencing, stroma, miRNA, immune infiltration

Prognostic role of microRNAs in breast cancer: A systematic review Review

Eleni Zografos, Flora Zagouri, Despoina Kalapanida, Roubini Zakopoulou, Anastasios Kyriazoglou, Kleoniki Apostolidou, Maria Gazouli, Meletios-Athanasios Dimopoulos

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7156-7178

Keywords: breast cancer, microRNAs, prognosis, biomarkers

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Ewa M. Kosciuczuk, Aroop K. Kar, Gavin T. Blyth, Mariafausta Fischietti, Sameem Abedin, Alain A. Mina, Rebekah Siliezar, Tomasz Rzymski, Krzysztof Brzozka, Elizabeth A. Eklund, Elspeth M. Beauchamp, Frank Eckerdt, Diana Saleiro, Leonidas C. Platanias

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7112-7121

Keywords: acute myeloid leukemia, MNK, eIF4E, kinase inhibitor, SEL201

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

Hideyuki Matsushima, Masaki Kaibori, Masahiko Hatta, Morihiko Ishizaki, Richi Nakatake, Tadayoshi Okumura, Kengo Yoshii, Tomoki Todo

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7132-7141

Keywords: oncolytic virus, herpes simplex virus, neuroendocrine tumor, mouse xenograft model

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

Ali C. Ravanpay, Juliane Gust, Adam J. Johnson, Lisa S. Rolczynski, Michelle Cecchini, Cindy A. Chang, Virginia J. Hoglund, Rithun Mukherjee, Nicholas A. Vitanza, Rimas J. Orentas, Michael C. Jensen

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7080-7095

Keywords: glioblastoma, CAR T cell, EGFR, immunotherapy, mAb806

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Shlomit Brodie, Hae Kyung Lee, Wei Jiang, Simona Cazacu, Cunli Xiang, Laila M. Poisson, Indrani Datta, Steve Kalkanis, Doron Ginsberg, Chaya Brodie

Published Dec 11, 2019 · Vol. 12, No. 26 · pp. 2546-2547

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

Walter Blum, Thomas Henzi, László Pecze, Kim-Long Diep, Christian G. Bochet, Beat Schwaller

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6944-6956

Keywords: malignant mesothelioma, septin cytoskeleton, septin 7, forchlorfenuron, FCF

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

Sylvie Carmona, Jean-Michel Brunel, Rénaté Bonier, Véronique Sbarra, Stéphane Robert, Patrick Borentain, Dominique Lombardo, Eric Mas, René Gerolami

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6651-6667

Keywords: aminosterol, pancreas, liver, PTP1B, cancer

The impact of systemic precision medicine and immunotherapy treatments on brain metastases Review

Rowland H. Han, Gavin P. Dunn, Milan G. Chheda, Albert H. Kim

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6739-6753

Keywords: brain metastases, targeted therapy, precision medicine, immunotherapy, systemic therapy

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Andro Košec, Ruđer Novak, Paško Konjevoda, Vladimir Trkulja, Vladimir Bedeković, Lovorka Grgurević

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6713-6722

Keywords: melanoma, early stage, proteomics, tissue, biomarkers

Correction: A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Correction

Jingyu Zhu, Man Wang, Yang Yu, Huixin Qi, Kunkun Han, Juan Tang, Zubin Zhang, Yuanying Zeng, Biyin Cao, Chunhua Qiao, Hongjian Zhang, Tingjun Hou, Xinliang Mao

Published Nov 15, 2019 · Vol. 10, No. 65 · pp. 7010-7011

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Jolein Mijnes, Janina Tiedemann, Julian Eschenbruch, Janina Gasthaus, Sarah Bringezu, Dirk Bauerschlag, Nicolai Maass, Norbert Arnold, Jörg Weimer, Tobias Anzeneder, Peter A. Fasching, Matthias Rübner, Benjamin Bruno, Uwe Heindrichs, Jennifer Freres, Hanna Schulz, Ralf-Dieter Hilgers, Nadina Ortiz-Brüchle, Sonja von Serenyi, Ruth Knüchel, Vera Kloten, Edgar Dahl

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6494-6508

Keywords: liquid biopsy, breast cancer, early detection, hypermethylation, discriminative CpG dinucleotides

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Johannes Fänder, Heike Kielstein, Maximilian Büttner, Peter Koelblinger, Reinhard Dummer, Marcus Bauer, Diana Handke, Claudia Wickenhauser, Barbara Seliger, Simon Jasinski-Bergner

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6509-6525

Keywords: CD44, CD44v6, melanoma, microRNA, immune cell infiltration

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

Shelli R. Kesler, Rebecca A. Harrison, Melissa L. Petersen, Vikram Rao, Hannah Dyson, Kristin Alfaro-Munoz, Shiao-Pei Weathers, John de Groot

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6484-6493

Keywords: MRI, IDH, glioma, machine learning, connectomics

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Sean M. Flynn, Jacqueline Lesperance, Andrew Macias, Nikki Phanhthilath, Megan Rose Paul, Jong Wook Kim, Pablo Tamayo, Peter E. Zage

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6323-6333

Keywords: neuroblastoma, RXDX-105, CEP-32496, RET, BRAF

Correction: A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Correction

Alice Gerges Geagea, Manfredi Rizzo, Abdo Jurjus, Francesco Cappello, Angelo Leone, Giovanni Tomasello, Céline Gracia, Sahar Al Kattar, Liliane Massaad-Massade, Assaad Eid

Published Oct 23, 2019 · Vol. 10, No. 60 · pp. 6538-6539

Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Correction

Tsung-I Hsu, Ying-Jung Chen, Chia-Yang Hung, Yi-Chang Wang, Sin-Jin Lin, Wu-Chou Su, Ming-Derg Lai, Sang-Yong Kim, Qiang Wang, Keduo Qian, Masuo Goto, Yu Zhao, Yoshiki Kashiwada, Kuo-Hsiung Lee, Wen-Chang Chang, Jan-Jong Hung

Published Oct 23, 2019 · Vol. 10, No. 60 · pp. 6536-6537

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli, Andrew E. Hendifar

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6260-6268

Keywords: pancreatic neuroendocrine tumors, genomic profiling, proteomic profiling, molecular pathways, co-occurring alterations

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Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Prognostic role of microRNAs in breast cancer: A systematic review Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

The impact of systemic precision medicine and immunotherapy treatments on brain metastases Review

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Correction: A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Correction

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Correction: A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Correction

Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Correction

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Prognostic role of microRNAs in breast cancer: A systematic review Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

The impact of systemic precision medicine and immunotherapy treatments on brain metastases Review

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Correction: A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Correction

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Correction: A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin Correction

Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Correction

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper