The Oncosearch | Oncotarget

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

Sangeeta Ray Banerjee, Mrudula Pullambhatla, Hassan Shallal, Ala Lisok, Ronnie C. Mease, Martin G. Pomper

Published Dec 29, 2011 · Vol. 2, No. 12 · pp. 1244-1253

Keywords: Prostate-specific membrane antigen (PSMA), NAALADase, bivalent urea inhibitor, molecular imaging, multivalency, SPECT imaging

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

Paul M. Neilsen, Jacqueline E. Noll, Rachel J. Suetani, Renee B Schulz, Fares Al-Ejeh, Andreas Evdokiou, David P. Lane, David F. Callen

Published Dec 25, 2011 · Vol. 2, No. 12 · pp. 1203-1217

Keywords: mutant p53, p63, secretome, invasion

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Ming Wang, Andrei L. Gartel

Published Dec 25, 2011 · Vol. 2, No. 12 · pp. 1218-1226

Keywords: FOXM1, siRNA, breast cancer, Aurora B kinase

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Michal Sheffer, Amos J. Simon, Jasmine Jacob-Hirsch, Gideon Rechavi, Eytan Domany, David Givol, Gabriella D'Orazi

Published Dec 24, 2011 · Vol. 2, No. 12 · pp. 1191-1202

Keywords: hypoxia, cobalt, pathway analysis, Principal Component Analysis (PCA), cDNA microarray, colon cancer

Metformin: Multi-faceted protection against cancer Review

Sonia Del Barco, Alejandro Vazquez-Martin, SÃlvia CufÃ, Cristina Oliveras-Ferraros, Joaquim Bosch-Barrera, Jorge Joven, BegoÃ±a Martin-Castillo, Javier A Menendez

Published Dec 24, 2011 · Vol. 2, No. 12 · pp. 896-917

Keywords: Diabetes, cancer, metformin, cancer stem cells, senescence

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Paula Vainio, Laura Lehtinen, Tuomas Mirtti, Mika Hilvo, Tuulikki SeppÃ¤nen-Laakso, Johannes Virtanen, Anna Sankila, Stig Nordling, Johan Lundin, Antti Rannikko, Matej OreÅ¡iÄ, Olli Kallioniemi, Kristiina Iljin

Published Dec 22, 2011 · Vol. 2, No. 12 · pp. 1176-1190

Keywords: Prostate cancer, PLA2G7, drug target, biomarker, statins

Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis Research Paper

Patricia Alexandra Madureira, Richard Hill, Victoria Ann Miller, Carman Giacomantonio, Patrick WK Lee, David Morton Waisman

Published Dec 20, 2011 · Vol. 2, No. 12 · pp. 1075-1093

Keywords: ANXA2, reactive oxygen species (ROS), redox regulation, oxidative stress, tumorigenesis

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death Research Paper

Richard Hill, Patricia A. Madureira, David M. Waisman, Patrick W.K. Lee

Published Dec 20, 2011 · Vol. 2, No. 12 · pp. 1094-1108

Keywords: DNA-PKCS, p53, p21 transcription suppression

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors Research Paper

Valeria G. Antico Arciuch, Marika A. Russo, Mariavittoria Dima, Kristy S. Kang, Florence Dasrath, Xiao-Hui Liao, Samuel Refetoff, Cristina Montagna, Antonio Di Cristofano

Published Dec 20, 2011 · Vol. 2, No. 12 · pp. 1109-1126

Keywords: thyroid cancer, mouse model, anaplastic, glycolysis, PI3K, Pten, p53

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Dannis Gilbert Van Vuurden, Esther Hulleman, Olga L.M. Meijer, Laurine E. Wedekind, Marcel Kool, Hendrik Witt, W. Peter Vandertop, Thomas WÃ¼rdinger, David P. Noske, Gertjan J.L. Kaspers, Jacqueline Cloos

Published Dec 15, 2011 · Vol. 2, No. 12 · pp. 984-996

Keywords: PARP, radiation, medulloblastoma, ependymoma, glioma, pediatric

A Novel Dual Signaling Axis for NSP 5a3a induced apoptosis in Head and Neck Carcinoma Research Paper

Luca D'Agostino, Antonio Giordano

Published Dec 14, 2011 · Vol. 2, No. 12 · pp. 1055-1074

Keywords: NSP 5a3a, p73, TRAF2, DAXX, TRADD, Apoptosis, Cancer

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells Research Paper

Maeva Dufies, Arnaud Jacquel, Nathalie Belhacene, Guillaume Robert, Thomas Cluzeau, FrÃ©deric Luciano, Jill Patrice Cassuto, Sophie Raynaud, Patrick Auberger

Published Nov 30, 2011 · Vol. 2, No. 11 · pp. 874-885

Keywords: CML, Imatinib resistance, AXL, ERK1/2, PKC

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Hong Zhao, Jian wang, Yongqing Han, Zhen Huang, Jianming Ying, Xinyu Bi, Jianjun Zhao, Yi Fang, Haitao Zhou, Jianguo Zhou, Zhiyu Li, Yefan Zhang, Xue Yang, Tao Yan, Linfang Wang, Michael S Torbenson, Jianqiang Cai

Published Nov 16, 2011 · Vol. 2, No. 11 · pp. 886-891

Keywords: Hepatocellular Carcinoma, Hepatitis C Virus, ARID2, Tumor Suppressor, Interferon

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Akshal S. Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael J. Glantz, Wafik S. El-Deiry

Published Oct 8, 2011 · Vol. 2, No. 10 · pp. 752-760

Keywords: circulating tumor cells, carcinomatous meningitis, breast cancer, brain metastases, intrathecal chemotherapy, cancer monitoring

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Jean-Claude Chomel, Ali G. Turhan

Published Sep 22, 2011 · Vol. 2, No. 9 · pp. 713-727

Keywords: CML, tyrosine kinase inhibitors, leukemic stem cells, persistency, quiescence, undetectable molecular disease

Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers Methodological Reports

Benjamin R. Waterhouse, Merel Gijsen, Paul R. Barber, Iain D.C. Tullis, Borivoj Vojnovic, Anthony Kong

Published Sep 8, 2011 · Vol. 2, No. 9 · pp. 728-736

Keywords: HER (ErbB) receptors, EGFR, HER2 (ErbB2), dimerization, FRET, FLIM

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective

Lorena Nogueira, Patricia Ruiz-OntaÃ±on, Alfonso Vazquez-Barquero, Francisco Moris, Jose L. Fernandez-Luna

Published Sep 5, 2011 · Vol. 2, No. 8 · pp. 646-653

Keywords: NFÎºB, glioblastoma, senescence, IKK inhibitor

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer Research Perspective

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi, Janet A. Houghton

Published Aug 21, 2011 · Vol. 2, No. 8 · pp. 638-645

Keywords: Hedgehog signaling, Colon carcinoma, DNA damage

Targeting invadopodia to block breast cancer metastasis Research Perspective

Mark A Eckert, Jing Yang

Published Jun 30, 2011 · Vol. 2, No. 7 · pp. 562-568

Keywords: Twist1, PDGFR, Src, MMP, MT1-MMP, SFK, metastasis, invasion, breast cancer, invadopodia, podosomes

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells Research Perspective

Weibo Luo, Gregg L. Semenza

Published Jun 25, 2011 · Vol. 2, No. 7 · pp. 551-556

Keywords: HIF-1, hypoxia, metabolism, glycolysis, Warburg effect

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A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Metformin: Multi-faceted protection against cancer Review

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis Research Paper

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death Research Paper

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors Research Paper

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

A Novel Dual Signaling Axis for NSP 5a3a induced apoptosis in Head and Neck Carcinoma Research Paper

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers Methodological Reports

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer Research Perspective

Targeting invadopodia to block breast cancer metastasis Research Perspective

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA) Research Paper

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Metformin: Multi-faceted protection against cancer Review

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis Research Paper

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death Research Paper

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors Research Paper

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

A Novel Dual Signaling Axis for NSP 5a3a induced apoptosis in Head and Neck Carcinoma Research Paper

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells Research Paper

ARID2: A new tumor suppressor gene in hepatocellular carcinoma Research Perspective

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers Methodological Reports

The NFÎºB pathway: a therapeutic target in glioblastoma Research Perspective

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer Research Perspective

Targeting invadopodia to block breast cancer metastasis Research Perspective

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells Research Perspective