The Oncosearch | Oncotarget

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Stefanie Schlager, Carina Salomon, Sabine Olt, Christoph Albrecht, Anja Ebert, Oliver Bergner, Johannes Wachter, Francesca Trapani, Daniel Gerlach, Tilman Voss, Anna Traunbauer, Julian Jude, Matthias Hinterndorfer, Martina Minnich, Norbert Schweifer, Sophia M. Blake, Vittoria Zinzalla, Barbara Drobits, Darryl B. McConnell, Norbert Kraut, Mark Pearson, Johannes Zuber, Manfred Koegl

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 875-890

Keywords: BCL6, DLBCL, lymphoma, inducible CRISPR/Cas9, in vivo xenograft

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Ajay Kale, Afaf Aldahish, Girish Shah

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 858-874

Keywords: calcitonin receptor, T-antigen, tumor growth, PTEN, prostate cancer

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

Atsushi Tanaka, Yihua Zhou, Jinru Shia, Fiona Ginty, Makiko Ogawa, David S. Klimstra, Ronald C. Hendrickson, Julia Y. Wang, Michael H. Roehrl

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 813-824

Keywords: P4HA1, colorectal cancer, biomarker, prognosis, pathology

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Ryan P. Gilley, Peter H. Dube

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 740-754

Keywords: cancer immunotherapy, cancer vaccination, checkpoint blockade, melanoma, listeria

Prognostic value of a three-scale grading system based on combining molecular imaging with ⁶⁸Ga-DOTATATE and ¹⁸F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias Research Paper

Ioannis Karfis, Gwennaëlle Marin, Hugo Levillain, Stylianos Drisis, Raoul Muteganya, Gabriela Critchi, Loubna Taraji-Schiltz, Carlos Artigas Guix, Leila Shaza, Meriem Elbachiri, Laura Mans, Godelieve Machiels, Alain Hendlisz, Patrick Flamen

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 589-599

Keywords: gastroenteropancreatic neuroendocrine neoplasias, molecular imaging, prognostic biomarkers, ⁶⁸Ga-DOTATATE PET/CT, ¹⁸F-FDG PET/CT

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Rizwanul Haque, Shamsuzzama, Lalit Kumar, Tanuj Sharma, Soobiya Fatima, Pooja Jadiya, Mohammad I. Siddiqi, Aamir Nazir

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 634-649

Keywords: Parkinson’s, human insulin, aggregation, Daf-2, Caenorhabditis elegans (C. elegans)

Risk factors for breast cancer brain metastases: a systematic review Review

Lola Koniali, Andreas Hadjisavvas, Anastasia Constantinidou, Kyproula Christodoulou, Yiolanda Christou, Christiana Demetriou, Andreas S. Panayides, Constantinos Pitris, Constantinos S. Pattichis, Eleni Zamba-Papanicolaou, Kyriacos Kyriacou

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 650-669

Keywords: breast cancer, brain metastases, risk factors, biomarkers

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Richard K. Yang, Yun Qing, Fatima Zahra Jelloul, Mark J. Routbort, Peng Wang, Kenna Shaw, Jiexin Zhang, Jack Lee, L. Jeffrey Medeiros, Scott Kopetz, Michael T. Tetzlaff, Russell R. Broaddus

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 600-618

Keywords: biomarkers, immunotherapy, mutations, TMB, histology

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Raquel Carvalho Montenegro, Alison Howarth, Alessandro Ceroni, Vita Fedele, Batoul Farran, Felipe Pantoja Mesquita, Martin Frejno, Benedict-Tilman Berger, Stephanie Heinzlmeir, Heba Z. Sailem, Roberta Tesch, Daniel Ebner, Stefan Knapp, Rommel Burbano, Bernhard Kuster, Susanne Müller

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 535-549

Keywords: gastric cancer, dasatinib, biomarker, SRC-kinases, SIK2

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Manish Charan, Piyush Dravid, Maren Cam, Bhuvana Setty, Ryan D. Roberts, Peter J. Houghton, Hakan Cam

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 510-522

Keywords: pre-metastatic niche formation, osteosarcoma, ANGPTL2, tumor microenvironment, neutrophils

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luca Zammataro, Aranzazu Manzano, Paola Manara, Elena Ratner, Dan-Arin Silasi, Gloria S. Huang, Masoud Azodi, Peter E. Schwartz, Francesco Raspagliesi, Roberto Angioli, Natalia Buza, Pei Hui, Heather M. Bond, Alessandro D. Santin

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 560-570

Keywords: sacituzumab govitecan, IMMU-132, uterine carcinosarcoma, trop-2

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

James Jabalee, Rebecca Towle, James Lawson, Christopher Dickman, Cathie Garnis

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 523-534

Keywords: oral squamous cell carcinoma, DNA methylation, SMPD3, erlotinib, cancer progression

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Chie Nakashima, Kazuhiko Yamamoto, Shingo Kishi, Takamitsu Sasaki, Hitoshi Ohmori, Rina Fujiwara-Tani, Shiori Mori, Isao Kawahara, Yukiko Nishiguchi, Takuya Mori, Masuo Kondoh, Yi Luo, Tadaaki Kirita, Hiroki Kuniyasu

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 309-321

Keywords: clostridium perfringens enterotoxin, claudin-4, YAP, Hippo signal, oral squamous cell carcinoma, Pathology

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Henri Montaudié, Julien Viotti, Patrick Combemale, Caroline Dutriaux, Nicolas Dupin, Caroline Robert, Laurent Mortier, Régis Kaphan, Anne-Bénédicte Duval-Modeste, Stéphane Dalle, Julie De Quatrebarbes, Andrea Stefan, Florence Brunet-Possenti, Maria Kogay, Alexandra Picard-Gauci, Gilles Poissonnet, Frédéric Peyrade

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 378-385

Keywords: cutaneous squamous cell carcinoma, cetuximab, epidermal growth factor receptor

FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary Research Paper

Francois Kraus, Julie Dremaux, Wajd Altakfi, Magalie Goux, Léa Pontois, Henri Sevestre, Stéphanie Trudel

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 419-428

Keywords: granulosa cell tumor, recurrence, FOXL2, array comparative genomic hybridization, chromosome instability

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Evan A. Clayton, Shareef Khalid, Dongjo Ban, Lu Wang, I. King Jordan, John F. McDonald

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 462-479

Keywords: allele-specific expression, alternative splicing, antisense RNA, cancer, tumor-suppressor genes

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Verena Schmitt, Gunther Wennemuth, Alexej Schmidt, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 429-439

Keywords: carcinoembryonic antigen, CEACAM, colon cancer, fluorescence, near-infrared

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew J. LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 265-281

Keywords: SHP2, FGFR, resistance, feedback activation

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report

Dmitry M. Ponomarenko, Vladimir L. Gabai, Albert A. Sufianov, Sergey I. Kolesnikov, Alexander M. Shneider

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 294-299

Keywords: cancer immunotherapy, cancer chemotherapy, p62 plasmid, cancer vaccine

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. McNulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 216-236

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

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Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Prognostic value of a three-scale grading system based on combining molecular imaging with ⁶⁸Ga-DOTATATE and ¹⁸F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Risk factors for breast cancer brain metastases: a systematic review Review

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Prognostic value of a three-scale grading system based on combining molecular imaging with 68Ga-DOTATATE and 18F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Risk factors for breast cancer brain metastases: a systematic review Review

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Prognostic value of a three-scale grading system based on combining molecular imaging with ⁶⁸Ga-DOTATATE and ¹⁸F-FDG PET/CT in patients with metastatic gastroenteropancreatic neuroendocrine neoplasias Research Paper