The Oncosearch | Oncotarget

The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

Francesca Coperchini, Laura Croce, Marco Denegri, Oriana Awwad, Samuel Tata Ngnitejeu, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6432-6443

Keywords: phenformin, tumor-microenvironment, thyroid cancer, CXCL8

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Jolein Mijnes, Janina Tiedemann, Julian Eschenbruch, Janina Gasthaus, Sarah Bringezu, Dirk Bauerschlag, Nicolai Maass, Norbert Arnold, Jörg Weimer, Tobias Anzeneder, Peter A. Fasching, Matthias Rübner, Benjamin Bruno, Uwe Heindrichs, Jennifer Freres, Hanna Schulz, Ralf-Dieter Hilgers, Nadina Ortiz-Brüchle, Sonja von Serenyi, Ruth Knüchel, Vera Kloten, Edgar Dahl

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6494-6508

Keywords: liquid biopsy, breast cancer, early detection, hypermethylation, discriminative CpG dinucleotides

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

Shelli R. Kesler, Rebecca A. Harrison, Melissa L. Petersen, Vikram Rao, Hannah Dyson, Kristin Alfaro-Munoz, Shiao-Pei Weathers, John de Groot

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6484-6493

Keywords: MRI, IDH, glioma, machine learning, connectomics

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Karina Juhl, Anders Christensen, Niclas Rubek, Kirstine Kim Schmidt Karnov, Christian von Buchwald, Andreas Kjaer

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6308-6316

Keywords: optical imaging, near-infrared imaging (NIR), NIR-I, urokinase plasminogen activator receptor (uPAR), cancer

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Gozde Uzunalli, Alexandra M. Dieterly, Chinyere M. Kemet, Hsin-Yi Weng, Arvin H. Soepriatna, Craig J. Goergen, Aparna B. Shinde, Michael K. Wendt, L. Tiffany Lyle

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6334-6348

Keywords: blood-brain barrier, blood-tumor barrier, non-small cell lung cancer, brain metastasis, aquaporin-4

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Inayatullah Shaikh, Afzal Ansari, Garima Ayachit, Monika Gandhi, Priyanka Sharma, Shivarudrappa Bhairappanavar, Chaitanya G. Joshi, Jayashankar Das

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6168-6183

Keywords: tobacco, head and neck squamous cell carcinoma (HNSCC), differentially expressed genes, hub gene, miRNA

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli, Andrew E. Hendifar

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6260-6268

Keywords: pancreatic neuroendocrine tumors, genomic profiling, proteomic profiling, molecular pathways, co-occurring alterations

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Abbas Hadji, Greta K. Schmitt, Mathew R. Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell, James L. LaBelle

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6219-6233

Keywords: MCL-1, BIM, BH3 mimetic, stapled peptides, apoptosis

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Bruna M. Sugita, Silma R. Pereira, Rodrigo C. de Almeida, Mandeep Gill, Akanksha Mahajan, Anju Duttargi, Saurabh Kirolikar, Paolo Fadda, Rubens S. de Lima, Cicero A. Urban, Kepher Makambi, Subha Madhavan, Simina M. Boca, Yuriy Gusev, Iglenir J. Cavalli, Enilze M.S.F. Ribeiro, Luciane R. Cavalli

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6184-6203

Keywords: microRNA, triple-negative breast cancer, copy number, latinas, disparities

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Shatha Albattal, Meshael Alswailem, Yosra Moria, Hindi Al-Hindi, Majed Dasouki, Mohamed Abouelhoda, Hala Aba Alkhail, Entissar Alsuhaibani, Ali S. Alzahrani

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5919-5931

Keywords: pheochromocytoma, paraganglioma, mutations, NGS, SDHB

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Pascale Ribaux, Aurore Britan, Gabriele Thumann, Florence Delie, Patrick Petignat, Marie Cohen

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5894-5905

Keywords: ascites, PEDF, sleeping beauty transposon, ovarian cancer, tumor development

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

Mark R. Woodford, Michael Hughes, Rebecca A. Sager, Sarah J. Backe, Alexander J. Baker-Williams, Michael S. Bratslavsky, Joseph M. Jacob, Oleg Shapiro, Michael Wong, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5824-5834

Keywords: tuberous sclerosis complex (TSC), Tsc1 (Hamartin), Tsc2 (Tuberin), heat shock protein (Hsp90), bladder cancer

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Athira Narayan, Yu Yan, Ala Lisok, Mary Brummet, Martin G. Pomper, Wojciech G. Lesniak, Robert F. Dannals, Vanessa F. Merino, Babak Behnam Azad

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5731-5744

Keywords: FDOPA, PET, neuroendocrine tumors, Fluorine-18, molecular imaging

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

Aimee T. Farria, Lisa Maria Mustachio, Zeynep H. Coban Akdemir, Sharon Y.R. Dent

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5847-5858

Keywords: GCN5, MYC, lymphoma, BCR

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Luana de O. Lopes, Jersey H. Maués, Hygor Ferreira-Fernandes, France K. Yoshioka, Severino C. Sousa Júnior, Alcemir R. Santos, Helem F. Ribeiro, Juan A. Rey, Paulo C. Soares, Rommel R. Burbano, Giovanny R. Pinto

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5768-5779

Keywords: stomach neoplasms, MYC oncogene, transcriptome, gene expression profiling, prognosis

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

Noura J. Choudhury, Mansooreh Eghtesad, Sabah Kadri, John Cursio, Lauren Ritterhouse, Jeremy Segal, Aliya Husain, Jyoti D. Patel

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5817-5823

Keywords: non-small cell lung cancer, healthcare disparities, targeted therapies, immunotherapies, biomarkers

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

Belen Alvarez-Palomo, Carme Barrot-Feixat, Helena Sarret, Jordi Requena, Montserrat Pau, Jose-Manuel Vidal-Taboada, Rafael Oliva, Josep-Lluis Ballesca, Michael J. Edel, Jovita Mezquita-Pla

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5871-5887

Keywords: ligand-independent intracellular iVEGFR-1 isoforms, mature testis, spermiogenesis, SRC activation, fertility

Clinicopathological correlation of immune response in human cancers Research Paper

Yuexin Liu

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5859-5870

Keywords: clinicopathological characteristics, immune response, immunogenicity, cancer

Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing Research Paper

Anna Streubel, Albrecht Stenzinger, Susann Stephan-Falkenau, Jens Kollmeier, Daniel Misch, Torsten Gerriet Blum, Torsten Bauer, Olfert Landt, Alexander Am Ende, Peter Schirmacher, Thomas Mairinger, Volker Endris

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5690-5702

Keywords: lung cancer, liquid biopsy, cfDNA, molecular diagnostics, T790M

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The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

Clinicopathological correlation of immune response in human cancers Research Paper

Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection Research Paper

Pre-surgical connectome features predict IDH status in diffuse gliomas Research Paper

Improved surgical resection of metastatic pancreatic cancer using uPAR targeted in vivo fluorescent guidance: comparison with traditional white light surgery Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Integrated copy number and miRNA expression analysis in triple negative breast cancer of Latin American patients Research Paper

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

A side-by-side evaluation of [18F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

Two novel ligand-independent variants of the VEGFR-1 receptor are expressed in human testis and spermatozoa, one of them with the ability to activate SRC proto-oncogene tyrosine kinases Research Paper

Clinicopathological correlation of immune response in human cancers Research Paper

Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing Research Paper

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper