The Oncosearch | Oncotarget

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Inês Gomes, Bernardo P. de Almeida, Sara Dâmaso, André Mansinho, Inês Correia, Sara Henriques, Raquel Cruz-Duarte, Guilherme Vilhais, Pedro Félix, Patrícia Alves, Patrícia Corredeira, Nuno L. Barbosa-Morais, Luis Costa, Sandra Casimiro

Published Apr 18, 2020 · Vol. 11, No. 19 · pp. 1714-1728

Keywords: RANKL-RANK pathway, ER+ breast cancer, resistance to chemo and hormone therapy, stemness, metastization

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuwei Liu, Kazuhiro Ooe, Takahiro Teramoto, Atsushi Toyoshima, Eku Shimosegawa, Takashi Nakano, Yoshikatsu Kanai, Atsushi Shinohara, Jun Hatazawa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1388-1398

Keywords: alpha therapy, astatine, glioma, LAT1, phenylalanine

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Apr 11, 2020 · Vol. 11, No. 18 · pp. 1618-1628

Keywords: squamous cell carcinoma of head and neck, immunotherapy, programmed cell death 1 receptor, kinetics

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal, Angshuman Sarkar

Published Apr 6, 2020 · Vol. 11, No. 18 · pp. 1603-1617

Keywords: quinacrine, NSCLC, RhoGTPases, apoptosis, cell cycle

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Nerymar Ortiz-Otero, Andrea B. Clinch, Jacob Hope, Wenjun Wang, Cynthia A. Reinhart-King, Michael R. King

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1037-1050

Keywords: metastasis, cancer associated fibroblasts, circulating tumor cells, cytoprotection, collective migration

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper

Anna Huo-Chang Mei, Kaity Tung, Jessie Han, Deepak Perumal, Alessandro Laganà, Jonathan Keats, Daniel Auclair, Ajai Chari, Sundar Jagannath, Samir Parekh, Hearn Jay Cho

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 727-739

Keywords: MAGE-A3, multiple myeloma, apoptosis, cell cycle regulation, DNA repair

Correction: Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth Correction

Lu-Lu Wang, Hui-Hui Guo, Yun Zhan, Chen-Lin Feng, Shuai Huang, Yan-Xing Han, Wen-Sheng Zheng, Jian-Dong Jiang

Published Feb 13, 2020

Risk factors for breast cancer brain metastases: a systematic review Review

Lola Koniali, Andreas Hadjisavvas, Anastasia Constantinidou, Kyproula Christodoulou, Yiolanda Christou, Christiana Demetriou, Andreas S. Panayides, Constantinos Pitris, Constantinos S. Pattichis, Eleni Zamba-Papanicolaou, Kyriacos Kyriacou

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 650-669

Keywords: breast cancer, brain metastases, risk factors, biomarkers

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Orly Ben-Nun-Shaul, Rohit Srivastava, Sharona Elgavish, Shashi Gandhi, Yuval Nevo, Hadar Benyamini, Arieh Eden, Ariella Oppenheim

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 574-588

Keywords: sepsis, empty SV40 capsids, RNAseq, signaling, cellular functions

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Richard K. Yang, Yun Qing, Fatima Zahra Jelloul, Mark J. Routbort, Peng Wang, Kenna Shaw, Jiexin Zhang, Jack Lee, L. Jeffrey Medeiros, Scott Kopetz, Michael T. Tetzlaff, Russell R. Broaddus

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 600-618

Keywords: biomarkers, immunotherapy, mutations, TMB, histology

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

Beatrice Aramini, Federico Banchelli, Stefania Bettelli, Samantha Manfredini, Roberto D’Amico, Valentina Masciale, Massimo Pinelli, Margherita Moretti, Alessandro Stefani, Federica Bertolini, Massimo Dominici, Uliano Morandi, Antonino Maiorana

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 550-559

Keywords: somatic mutations, non-small cell lung cancer (NSCLC), lung cancer treatment, overall survival, target therapy

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luca Zammataro, Aranzazu Manzano, Paola Manara, Elena Ratner, Dan-Arin Silasi, Gloria S. Huang, Masoud Azodi, Peter E. Schwartz, Francesco Raspagliesi, Roberto Angioli, Natalia Buza, Pei Hui, Heather M. Bond, Alessandro D. Santin

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 560-570

Keywords: sacituzumab govitecan, IMMU-132, uterine carcinosarcoma, trop-2

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Devakumar Sundaravinayagam, Hye Rim Kim, TingTing Wu, Hyun Hee Kim, Hyun-Seo Lee, Semo Jun, Jeong-Heon Cha, Younghoon Kee, Ho Jin You, Jung-Hee Lee

Published Jan 30, 2020 · Vol. 11, No. 21 · pp. 2024-2025

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer Research Paper

Vanita Noronha, Vijay Maruti Patil, Amit Joshi, Manoj Mahimkar, Usha Patel, Manish Kumar Pandey, Arun Chandrasekharan, Hollis Dsouza, Atanu Bhattacharjee, Abhishek Mahajan, Nilesh Sabale, Jai Prakash Agarwal, Sarbani Ghosh-Laskar, Ashwini Budrukkar, Anil K. D’Cruz, Pankaj Chaturvedi, Prathamesh S. Pai, Devendra Chaukar, Sudhir Nair, Shivakumar Thiagarajan, Shripad Banavali, Kumar Prabhash

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 399-408

Keywords: HPV negative, oropharynx, nimotuzumab, weekly, cisplatin

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Verena Schmitt, Gunther Wennemuth, Alexej Schmidt, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 429-439

Keywords: carcinoembryonic antigen, CEACAM, colon cancer, fluorescence, near-infrared

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew J. LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 265-281

Keywords: SHP2, FGFR, resistance, feedback activation

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Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper

Correction: Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth Correction

Risk factors for breast cancer brain metastases: a systematic review Review

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Targeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21Cip1 Research Paper

Correction: Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth Correction

Risk factors for breast cancer brain metastases: a systematic review Review

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies Research Paper

Overall survival in patients with lung adenocarcinoma harboring “niche” mutations: an observational study Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Correction: miR146a-mediated targeting of FANCM during inflammation compromises genome integrity Correction

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer Research Paper

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models Research Paper

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper