The Oncosearch | Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Lanlan Zhou, Kelsey Huntington, Shengliang Zhang, Lindsey Carlsen, Eui-Young So, Cassandra Parker, Ilyas Sahin, Howard Safran, Suchitra Kamle, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Kerry S. Campbell, Mandar T. Naik, Walter J. Atwood, Emile Youssef, Jonathan A. Pachter, Arunasalam Navaraj, Attila A. Seyhan, Olin Liang, Wafik S. El-Deiry

Published Oct 28, 2020

Keywords: ACE2, TMPRSS2, SARS-CoV-2, COVID-19, pseudovirus

Glasgow prognostic score is a better predictor of the long-term survival in patients with gastric cancer, compared to the modified Glasgow prognostic score or high-sensitivity modified Glasgow prognostic score Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yasunari Kawabata, Ryoji Hyakudomi, Tetsu Yamamoto, Yuki Uchida, Kazunari Ishitobi, Kiyoe Takai, Yoshitsugu Tajima

Published Oct 27, 2020 · Vol. 11, No. 45 · pp. 4169-4177

Keywords: glasgow prognostic score (GPS), modified GPS (mGPS), high-sensitivity mGPS (HS-mGPS), C-reactive protein, gastric cancer

Significance of mesothelin expression in preoperative endoscopic biopsy specimens for colorectal cancer prognosis Research Paper

Takehiro Shiraishi, Eiji Shinto, Masato Yamadera, Ken Nagata, Hitoshi Tsuda, Satsuki Mochizuki, Yoshiki Kajiwara, Koichi Okamoto, Takahiro Einama, Yoji Kishi, Hideki Ueno

Published Oct 6, 2020 · Vol. 11, No. 43 · pp. 3807-3817

Keywords: colorectal cancer, mesothelin, endoscopic biopsy specimen, immunohistochemistry, Pathology

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Thomas M. Cardillo, Diane L. Rossi, Maria B. Zalath, Donglin Liu, Roberto Arrojo, Robert M. Sharkey, Chien-Hsing Chang, David M. Goldenberg

Published Oct 1, 2020 · Vol. 11, No. 43 · pp. 3849-3862

Keywords: sacituzumab govitecan, Trop-2, biomarker, RAD51, triple-negative breast cancer

Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis Research Paper

Myoung Sook Kim, Ramkishore Gernapudi, Yessenia Cedeño Cedeño, Brian M. Polster, Ramon Martinez, Paul Shapiro, Santosh Kesari, Elmar Nurmemmedov, Antonino Passaniti

Published Sep 3, 2020 · Vol. 11, No. 43 · pp. 3863-3885

Keywords: mitochondrial ATP synthase, oxygen consumption rate, ATP synthesis, reactive oxygen species,

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, Shantaram S. Joshi

Published Jul 30, 2020 · Vol. 11, No. 40 · pp. 3633-3645

Keywords: exosomes, hypoxia, Ewing’s sarcoma, stemness, miR-210

Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers Research Paper

Takeyuki Suzuki, Tetsutaro Suzuki, Yukino Yoshimura, Mitsunori Yahata, Poh Yin Yew, Tetsuya Nakamura, Yusuke Nakamura, Jae-Hyun Park, Ryota Matsuo

Published Jul 15, 2020 · Vol. 11, No. 34 · pp. 3198-3207

Keywords: ctDNA, early detection, liquid biopsy, mutation, recurrence

Geriatric nutritional risk index as a prognostic marker of pTNM-stage I and II esophageal squamous cell carcinoma after curative resection Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Yusuke Fujii, Shunsuke Kaji, Ryoji Hyakudomi, Tetsu Yamamoto, Yuki Uchida, Yoshiko Miyazaki, Kazunari Ishitobi, Yasunari Kawabata, Yoshitsugu Tajima

Published Jun 29, 2020 · Vol. 11, No. 29 · pp. 2834-2846

Keywords: geriatric nutritional risk index, esophageal squamous cell carcinoma, curative esophagectomy, cancer-specific survival, pathological tumor-node-metastasis

Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma Research Paper

Pavitra Murali, Blake P. Johnson, Zhongpeng Lu, Leslie Climer, Danielle A. Scott, Francois Foulquier, Gabriela Oprea-Ilies, Vladimir Lupashin, Richard R. Drake, Karen L. Abbott

Published Jun 27, 2020 · Vol. 11, No. 28 · pp. 2747-2762

Keywords: TMEM165, migration, invasion, breast cancer, glycosylation

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer Research Paper

Takemasa Tsuji, Kevin H. Eng, Junko Matsuzaki, Sebastiano Battaglia, J. Brian Szender, Anthony Miliotto, Sacha Gnjatic, Wiam Bshara, Carl D. Morrison, Shashikant Lele, Ryan O. Emerson, Jianmin Wang, Song Liu, Harlan Robins, Amit A. Lugade, Kunle Odunsi

Published Jun 23, 2020 · Vol. 11, No. 27 · pp. 2669-2683

Keywords: T-cell repertoire, ovarian cancer, tumor immunity

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Abhay Kumar Singh, Vaishali Kapoor, Dinesh Thotala, Dennis E. Hallahan

Published Jun 22, 2020 · Vol. 11, No. 27 · pp. 2647-2659

Keywords: TAF15, radiation inducible, lung cancer, antibody

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Yusuke Fujii, Shunsuke Kaji, Yasunari Kawabata, Ryoji Hyakudomi, Tetsu Yamamoto, Takahito Taniura, Yoshitsugu Tajima

Published Jun 12, 2020 · Vol. 11, No. 27 · pp. 2625-2635

Keywords: gastric cancer, systemic immune-inflammation index, CRP, overall survival

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

Joshua T. Rose, Eliana Moskovitz, Joseph R. Boyd, Jonathan A. Gordon, Nicole A. Bouffard, Andrew J. Fritz, Anuradha Illendula, John H. Bushweller, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi, Gary S. Stein

Published May 30, 2020 · Vol. 11, No. 26 · pp. 2512-2530

Keywords: mammary epithelial phenotype, epithelial phenotype, RUNX1, CBFβ, mitotic gene bookmarking

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published May 22, 2020 · Vol. 11, No. 26 · pp. 2464-2483

Keywords: miR-708-5p, miR-708, lung cancer, COX-2, mPGES-1

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

Silvia P. Corona, Fabiola Giudici, Guy Jerusalem, Eva Ciruelos, Carla Strina, Marianna Sirico, Ottavia Bernocchi, Manuela Milani, Martina Dester, Nicoletta Ziglioli, Giuseppina Barbieri, Valeria Cervoni, Filippo Montemurro, Daniele Generali

Published May 19, 2020 · Vol. 11, No. 23 · pp. 2172-2181

Keywords: BMI, weight, everolimus, metastatic breast cancer, outcomes

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Anke Vermehren-Schmaedick, Paulette Mhawech-Fauceglia, Byung S. Park, Tanja Pejovic, Shiuh-Wen Luoh

Published May 1, 2020 · Vol. 11, No. 24 · pp. 2273-2289

Keywords: GRB7 expression, breast cancer, ovarian cancer, immunohistochemistry, prognosis

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini

Published Apr 22, 2020 · Vol. 11, No. 19 · pp. 1737-1748

Keywords: protein-protein interaction, leukaemia, T-ALL, drug discovery, LMO2

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

Ayushi Vashishtha, Tae Jin Lee, Ashok Sharma, John J. Wallbillich

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1435-1447

Keywords: uveal melanoma, metastasis, survival, microRNA, biomarker

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Mei Zhang, Angela M. Hong

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1417-1426

Keywords: radiosensitivity, oropharyngeal cancer, human papillomavirus, double-strand break, radiobiology

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Anindita Tripathy, Sudhir Thakurela, Manoj Kumar Sahu, Kanishka Uthansingh, Ayaskanta Singh, Jimmy Narayan, Amrendra Kumar Ajay, Vinay Singh, Ratna Kumari

Published Apr 20, 2020

Keywords: hepatocellular carcinoma, adiposity, SHH-E2F1 pathway, lipogenic molecules, adiponectin

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Glasgow prognostic score is a better predictor of the long-term survival in patients with gastric cancer, compared to the modified Glasgow prognostic score or high-sensitivity modified Glasgow prognostic score Research Paper

Significance of mesothelin expression in preoperative endoscopic biopsy specimens for colorectal cancer prognosis Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers Research Paper

Geriatric nutritional risk index as a prognostic marker of pTNM-stage I and II esophageal squamous cell carcinoma after curative resection Research Paper

Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma Research Paper

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Glasgow prognostic score is a better predictor of the long-term survival in patients with gastric cancer, compared to the modified Glasgow prognostic score or high-sensitivity modified Glasgow prognostic score Research Paper

Significance of mesothelin expression in preoperative endoscopic biopsy specimens for colorectal cancer prognosis Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers Research Paper

Geriatric nutritional risk index as a prognostic marker of pTNM-stage I and II esophageal squamous cell carcinoma after curative resection Research Paper

Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma Research Paper

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Comparison of the prognostic value of immunoinflammation-based biomarkers in patients with gastric cancer Research Paper

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

The prognostic significance of GRB7 protein expression and localization in human breast and ovarian cancers Research Paper

Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Research Paper

Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper